Potentiates

A new Eph receptor tyrosine kinase overexpressed in gastric cancer was found

...dly forms a hetero receptor complex with FGFR1 and that EphA4/FGFR1 complex potentiates FGFR-mediated downstream signal transduction. However, alterations of EphA4...forms a hetero receptor complex with FGFR1 and that the EphA4/FGFR1 complex potentiates FGFR-mediated downstream signal transduction. FGFR1 expression was correlat...

Ancient mechanism for coping with stresses also gives cancer a boost

... "Strikingly, our data now make clear that HSF1 plays opposite roles in the complex diseases that plague aging populations," she said. "It powerfully potentiates the development of cancers. But it has also been implicated in protection against ischemia/re-perfusion injury, neurodegenerative disorders and in oth...

New Strategy for the Treatment of CML

... is a clear priority, resistance of leukemia cells to these novel agents may also develop,” said Grant. “Addition of a second, targeted agent that potentiates the activity of dasatinib may reduce the leukemic burden further, and thereby reduce, or possibly even prevent the emergence of drug resistance. If va...

Potentiates in Medical Technology

Cardium Reports on Applicability of Corgentin to Stem Cell Therapies: Independent Studies Indicate that Ad5IGF-1 Potentiates Stem Cells to Improve Cardiac Function After Heart Attack

SAN DIEGO, March 27 /PRNewswire-FirstCall/ -- Cardium Therapeutics (NYSE Amex: CXM ) today reported on an NIH-funded, pre-clinical study conducted by independent researchers at the University of Cincinnati entitled IGF-1--Overexpressing Mesenchymal Stem Cells Accelerate Bone Marrow Stem Cell ...

YM BioSciences Announces Preclinical Data Confirming Nimotuzumab Binds to the EGF Receptor and Potentiates Radiotherapy

MISSISSAUGA, ON, July 09, 2007 /PRNewswire-FirstCall/ - YM BioSciences Inc. , an oncology company that identifies, develops and commercializes differentiated products for patients worldwide, today announced that a study presented by investigators from Kinki University School of Medicine and Kyoto ...

Romark Announces Presentation of New Data for Nitazoxanide in Chronic Hepatitis C at EASL 2008

...cated that treatment with nitazoxanide alone prior to adding interferon potentiates the activity of combination therapy with nitazoxanide plus peginterfero... also demonstrated that treatment of HCV replicon cells with tizoxanide potentiates the antiviral effect of subsequent treatment with interferon (8-fold ...

Potentiates in Biological News

Study links nicotine with breast cancer growth and spread

...AChR and that nicotine, possibly through perturbing cell cycle checkpoints, potentiates tumorigenesis in mammary cancer-prone or cancer cells," Chen said. In v...icotine alone," said Chen. "At this point we can only suggest that nicotine potentiates the growth-related process." Chen hopes to conduct more studies, in part...

Potentiates in Biological Technology

Sunesis Pharmaceuticals to Present Data at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

... multiple myeloma xenografts Wednesday, October 24, 2007 * Poster Session B - Other Small Molecule Therapeutics Abstract No. B285 SNS-595 potentiates the in vivo anti-tumor activity of carboplatin, cisplatin and gemcitabine in solid tumor xenografts All posters will be presented in the Moscone ...

YM BIOSCIENCES REPORTS 2007 YEAR END OPERATIONAL AND FINANCIAL RESULTS

...nufacturing of nimotuzumab. - YM reported preclinical data separately confirming that nimotuzumab binds to the EGF receptor and that it also potentiates radiotherapy in non-small-cell lung cancer cells. Subsequent to the end of the fiscal year: - YM USA was cleared by the US FDA to expand its ...

Your Data: Use of pSilencer 1.0-U6 siRNA Expression Vector in the Analysis of Synaptotagmin Location and Function

...that Syt V and Syt IX act as positive modulators of exocytosis. The addition of the phorbol ester PMA, which potentiates insulin exocytosis distal to the increase of cytosolic Ca 2+ showed that both proteins are directly involve...

RT-PCR Primers for the Study of Apoptosis

...r the Fas ligand or the anti-Fas antibody rapidly stimulates the proteolytic activity of ICE proteins. Overexpression of the ICE proteins strongly potentiates Fas-mediated cell death; inhibitors of ICE proteins inhibit the apoptotic process. Thus, determining the expression of ICE family proteins is an i...

Potentiates in Biological Dictionary

Myosin

...ractile units (sarcomeres) of skeletal ... External link: Myosin Homepage. Neuromuscular junction. Presynaptic. Postsynaptic. Smooth muscle ... potentiates actin- myosin interaction at low Ca++ levels ... Definition and other additional information on Myosin from Biology-Online.org dictionary. ... ...