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Postmenopausal in Medical News

QuatRx Announces Further Positive Phase 3 Results For Ophena(TM) (Ospemifene Tablets) in Postmenopausal Vaginal Atrophy

ANN ARBOR, Mich., July 29 /PRNewswire/ -- QuatRx Pharmaceuticals Company, a privately-held biopharmaceutical company, today announced positive top-line efficacy results from the first of two patient cohorts in its second pivotal Phase 3 trial of the investigational compound, Ophe...

FDA Approves Reclast(R) to Prevent Osteoporosis in Postmenopausal Women With Convenient Less Frequent Dosing

- Single infusion of Reclast increases bone mass for two years in postmenopausal women with osteopenia, a condition that can lead to osteoporosis(1) - Approximately 22 million women in US have osteopenia, or low bone mass, putting them at increased risk of fractures of hip, spine and wrist(2,...

Wyeth's CONBRIZA Approved in the European Union for Treatment of Postmenopausal Osteoporosis in Women at Increased Risk of Fracture

COLLEGEVILLE, Pa., April 27 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), announced today that the European Commission has granted marketing authorization for CONBRIZA(TM) (bazedoxifene), a selective estrogen receptor modulator (SERM), for the treatment of po...

CONBRIZA Receives Positive CHMP Opinion for the Treatment of Postmenopausal Osteoporosis in Women at Increased Risk of Fracture

COLLEGEVILLE, Pa., Feb. 19 /PRNewswire-FirstCall/ -- The Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European Medicines Agency (EMEA), today adopted a positive opinion recommending to grant a marketing authorization for CONBRIZA(TM) (bazedoxifene) for the...

Exercise Boosts Quality of Life in Postmenopausal Women

Study finds even without weight loss, general health, functioning improve FRIDAY, Feb. 13 (HealthDay News) -- Even if it doesn't help them lose weight, exercise can improve postmenopausal women's quality of life, a U.S. study shows. It included 430 sedentary postmenopausal women (a...

Multivitamin use may offer no benefit in postmenopausal women

February 9, 2009 (BRONX, NY) The largest study ever conducted on postmenopausal women shows that multivitamins may offer no benefit in reducing the risk of common cancers, cardiovascular disease or overall mortality. The study, published today in Archives of Internal Medicine , also shows that ...

UNC study: Postmenopausal women's loss of sexual desire affects health, quality of life

CHAPEL HILL Women with low levels of sexual desire, often as a result of menopause, are more likely to be depressed and to suffer physical symptoms such as back pain and memory problems than women who report higher levels of desire, according to a new study by researchers at the University of Nor...

High insulin levels raise risk of breast cancer in postmenopausal women

January 9, 2009 (BRONX, NY) Higher-than-normal levels of insulin place postmenopausal women at increased risk of breast cancer, researchers at Albert Einstein College of Medicine of Yeshiva University report. Their findings, published in the January 7 issue of the Journal of the National Canc...

FDA Approves Low-dose Regimen of PREMARIN Vaginal Cream to Treat Moderate to Severe Postmenopausal Dyspareunia – Painful Sexual Intercourse : Agency Grants New Indication for Bothersome Vaginal Symptom Associated with Menopause

PREMARIN (conjugated estrogens) Vaginal Cream 0.5 g has been approved by the U.S. Food and Drug Administration (FDA) for a new indication and a new less frequent twice-weekly dosing regimen to treat moderate to severe postmenopausal dyspareunia (painful sexual intercourse) announced Wyeth Pharmac...

FDA Approves Low-dose Regimen of PREMARIN Vaginal Cream to Treat Moderate to Severe Postmenopausal Dyspareunia - Painful Sexual Intercourse

Agency Grants New Indication for Bothersome Vaginal Symptom Associated With Menopause COLLEGEVILLE, Pa., Nov. 13 /PRNewswire-FirstCall/ -- PREMARIN(R) (conjugated estrogens) Vaginal Cream 0.5 g has been approved by the U.S. Food and Drug Administration (FDA) for a new indication and a new le...

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Postmenopausal in Medical Technology

Radius' Investigational Bone Anabolic Agent, BA058, Increased Bone Mineral Density (BMD) at Key Fracture Sites in Phase 2 Clinical Trial in Postmenopausal Osteoporosis

CAMBRIDGE, Mass., Aug. 5 /PRNewswire/ -- Radius Health ("Radius") today announced topline Phase 2 data demonstrating that in women with osteoporosis, BA058 -- the company's novel PTHrP (parathyroid hormone-related protein) analog -- significantly increased bone mineral density (BM...

QuatRx Completes Enrollment of Ophena(TM)(Ospemifene Tablets) Final Pivotal Phase 3 Study in Women with Postmenopausal Vaginal Atrophy

ANN ARBOR, Mich., March 31 /PRNewswire/ -- QuatRx Pharmaceuticals, a privately-held biopharmaceutical company, today announced that it has completed enrollment in the Company's second pivotal Phase 3 clinical trial of Ophena(TM) (ospemifene tablets). Together with the previously completed firs...

Phase III Trial Showed Investigational Compound Arzoxifene Was Superior to Evista(R) (raloxifene HCl) in Increasing BMD in Postmenopausal Women with Osteoporosis

Results from the "NEXT" Study Also Showed Arzoxifene Significantly Suppressed Bone Turnover Markers versus Raloxifene in Postmenopausal Women with Osteoporosis ATHENS, Greece, March 23 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY ) presented new data showing arzoxifene, an inv...

New Analyses Indicate that Divigel(R) (estradiol gel) 0.1% Is a Valuable Option for Certain Postmenopausal Women With Hot Flashes

- Transdermal Estrogen Analyses Continue to Show Benefits of Hormone Therapy Use in Menopausal Women - MAPLE GROVE, Minn., Sept. 25 /PRNewswire/ -- Upsher-Smith Laboratories, Inc. today announced that clinical abstracts featuring Divigel(R) (estradiol gel) 0.1% were present...

QuatRx Initiates Second Phase 3 Study of Ophena(TM) (Ospemifene Tablets) in Women With Postmenopausal Vaginal Syndrome

Pivotal Study Seeks to Enroll 750 Women at More Than 100 Sites in the U.S. ANN ARBOR, Mich., Sept. 4 /PRNewswire/ -- QuatRx Pharmaceuticals, a privately-held biopharmaceutical company focused on development and commercialization of compounds to treat endocrine, metabolic and cardiovascular diso...

Wyeth Receives Approvable Letter From FDA for Bazedoxifene for the Treatment of Postmenopausal Osteoporosis

COLLEGEVILLE, Pa., May 23 /PRNewswire/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), announced today that the U.S. Food and Drug Administration (FDA) issued an approvable letter on May 21 for bazedoxifene, a selective estrogen receptor modulator, for the treatment of postmenopau...

Phase III Data Published for Once Monthly Dose of Risedronate to Treat Postmenopausal Osteoporosis

BRIDGEWATER, N.J. and CINCINNATI, Jan. 14 /PRNewswire-FirstCall/ -- Results from a Phase III clinical trial evaluating the efficacy and safety of risedronate 150 mg once monthly for the treatment of postmenopausal osteoporosis were published this month in the January issue of the peer- reviewe...

QuatRx Pharmaceuticals Announces Positive Phase 3 Results for Study of Ophena(TM) (ospemifene) to Treat Postmenopausal Vaginal Syndrome

Novel non-estrogen oral therapy in development for menopausal symptoms ANN ARBOR, Mich., Jan. 3 /PRNewswire/ -- QuatRx Pharmaceuticals Company today announced positive results from a pivotal Phase 3 study of Ophena(TM) (ospemifene) to treat postmenopausal women with vulvovaginal atrophy, a co...

New Study Shows Once-Monthly Boniva(R) is as Clinically Effective as Once-Weekly Fosamax(R) at Increasing Bone Mineral Density in Postmenopausal Women With Osteoporosis

HONOLULU, Sept. 19 /PRNewswire/ -- Women with postmenopausal osteoporosis receiving once-monthly Boniva(R) (ibandronate sodium) achieved clinically comparable increases in bone mineral density (BMD) to those receiving once-weekly Fosamax(R) (alendronate sodium), according to a new study presen...

New Phase III Data Presented for Once Monthly Dosing Regimen of Risedronate to Treat Postmenopausal Osteoporosis

HONOLULU, Sept. 19 /PRNewswire-FirstCall/ -- Results from a Phase III clinical trial evaluating the efficacy and safety of risedronate 150 mg once monthly for the treatment of postmenopausal osteoporosis were presented at the American Society for Bone and Mineral Research (ASBMR) 29th Annual M...
Postmenopausal in Medical Products

Estrone RIA Test

Description:... the adrenal cortex or gonads [1,2]. In premenopausal adult women, more than 50% of estrone is secreted by the ovary. In prepubertal children, men and postmenopausal women, the major portion of estrone is derived from peripheral tissue conversion of androstenedione. Interconversion of estrone and estradiol also occ...
Company:Diagnostic Systems Laboratories, Inc.

Estrone Sulfate, Ultra-Sensitive RIA Test

Description:...chusetts, Blackwell Scientific Publications, Inc. 1991, p.69. Levant SG & Barnes RB: Pharmacology of estrogen. IN: Lobo RA (ed.): Treatment of the postmenopausal Woman. New York: Raven Press, 1993, p.57. Buster JE: Estrogen metabolism. IN: Sciarra JJ (ed.): Endocrinology, Infertility, Genetics, Volume 5. Ph...
Company:Diagnostic Systems Laboratories, Inc.

Estrone Sulfate RIA Test

Description:...chusetts, Blackwell Scientific Publications, Inc. 1991, p.69. Levant SG & Barnes RB: Pharmacology of estrogen. IN: Lobo RA (ed.): Treatment of the postmenopausal Woman. New York: Raven Press, 1993, p.57. Buster JE: Estrogen metabolism. IN: Sciarra JJ (ed.): Endocrinology, Infertility, Genetics, Volume 5. Ph...
Company:Diagnostic Systems Laboratories, Inc.
Postmenopausal in Medical Dictionary

Weight gain

...ss and imbalance mean weight gain . ... Weight gain or loss can also be related to imbalance in our ... Calcium/vitamin D supplements slow postmenopausal weight gain in women who aren't getting enough ... Photos: Weight Gain Shockers. Health Benefits of Chocolate ... How do you explain weig...

Hormone replacement therapy

...to as "treatment" rather than therapy , is a system of medical treatment for surgically menopausal, perimenopausal and to a lesser extent postmenopausal women, based on the... Hormone replacement therapy (HRT) for transgender and transsexual people replaces the hormones naturally occurring in the...

Estrogen

...estrogen replacement were compared to control groups of women on other ... postmenopausal therapy with estrogen plus progestin puts women with coronary ... Lea...up of ... These secondary sources of estrogen are especially important in postmenopausal women. ... estrogen patch side effects replacement therapy symptom a...

Calcitonin

...citonin and parathyroid hormone? ... Drug information about Calcitonin -salmon (Miacalcin, Fortical, Calcimar) prescribed for the treatment of postmenopausal osteoporosis, Paget's disease of the bone, ... Learn about the prescription medication Miacalcin ( Calcitonin -Salmon), drug uses, dosage, s...

Atrophic vaginitis

...on including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. Up to 40 percent of postmenopausal women have symptoms of atrophic vaginitis . ... Atrophic vaginitis may be clinically diagnosed with the support of tests that ... Covers th...
Postmenopausal in Biological News

Vitamin K does not stem BMD decline in postmenopausal women with osteopenia

In a randomized controlled trial called the "Evaluate the Clinical use of vitamin K Supplementation in Postmenopausal Women with Osteopenia" (ECKO) trial, Angela Cheung and colleagues at the University of Toronto found that a high dose daily vitamin K1 supplement did not protect against age-relate...

A 'heart healthy' diet and ongoing, moderate physical activity may protect against cognitive decline

... long-term strenuous and moderate activity levels and cognition in recently postmenopausal women. Study participants were 90 women aged 50-63 years, one to 10 year...trenuous activity may increase the risk of cognitive impairment in recently postmenopausal women," Tierney said. "On the other hand, moderate long-term physical acti...

Two dietary oils, two sets of benefits for older women with diabetes

...h oils, by themselves, can lower body fat in obese postmenopausal women with Type 2 diabetes. The two oils compar...y composition is both achievable and affordable to postmenopausal women in the United States who are managing the di...ken each day was approximately 1 2/3 teaspoons. postmenopausal women tend to lose muscle at the same time that bo...

Study finds link between hot flashes and lower bone density in women

...her women with vasomotor symptoms (VMS) which include hot flashes and night sweats had lower bone mineral density. The researchers found that postmenopausal women with VMS had lower lumbar and total hip bone mineral density than those without VMS. Premenopausal women and early perimenopausal women who had ...

Red wine vs. white? It makes no difference when it comes to breast-cancer risk

...tion (red wine, white wine, liquor and beer) and other breast-cancer risk factors, such as age at first pregnancy, family history of breast cancer and postmenopausal hormone use. The study participants, ages 20 to 69, were from Wisconsin, Massachusetts and New Hampshire. The frequency of alcohol consumption was sim...

Gene therapy demonstrates benefit in patients with rheumatoid arthritis

...six study subjects following severe adverse events in an unrelated gene therapy trial taking place elsewhere, according to Evans.) Both subjects were postmenopausal females under the age of 75 with a diagnosis of advanced rheumatoid arthritis. After tissue was removed from the subjects' knuckle joints, a harmless ...

Hormone therapy associated with reduced colorectal cancer risk

... among women who had completed use of estrogen plus progestin five or more years previously. Johnson and her colleagues extracted data from 56,733 postmenopausal women who participated in the Breast Cancer Detection Demonstration Project follow-up study. Hormone therapy use and other risk factors were ascertain...

Mayo Clinic research on tamoxifen leads to recommendation for CYP2D6 gene test

...c researchers to recommend CYP2D6 gene testing for postmenopausal women about to begin tamoxifen therapy. This data ...usly discovered that the drug is less effective in postmenopausal breast cancer patients who had a deficiency in the... Clinic, "and strongly suggest that going forward, postmenopausal patients being considered for tamoxifen therapy sh...

Birth control has long-term effect on hormone exposure

...emoved, making them surgically menopausal. The postmenopausal monkeys were then divided into three dietary inter...each monkey during the 35th and 36th months of the postmenopausal phase of the study and frozen for subsequent analy...n in 2OHE1 with oral contraceptive administration. postmenopausal dietary isoflavones induced fewer significant effe...

Growth factor predicts poor outcome in breast cancer

...the effects of an IGF receptor antibody combined with a drug called exemestane (Aromasin or an aromatase inhibitor that blocks estrogen production) in postmenopausal women. One group of women take the combination and the other takes exemestane. Bioinformatics the ability to analyze large amounts of data pro...
Postmenopausal in Biological Technology

Amgen to Collaborate With GlaxoSmithKline to Commercialize Denosumab in Europe for Postmenopausal Osteoporosis (PMO)

THOUSAND OAKS, Calif. and LONDON, July 27 /PRNewswire-FirstCall/ -- Amgen (Nasdaq: AMGN ) and GlaxoSmithKline (GSK) today announced a collaboration in which the companies will share commercialization of Amgen's monoclonal antibody denosumab for postmenopausal osteoporosi...

Reclast(R) Receives US FDA Approval as First and Only Once-Yearly Treatment for Women With Postmenopausal Osteoporosis

- Shown to be highly effective in strengthening bones and protecting against osteoporosis-related fractures, including spine and hip - Reclast reduced spine fractures by 70% and hip fractures by 41% compared to placebo in study published in New England Journal of Medicine - Unique once...

Amgen to Participate in Reproductive Health Drugs Advisory Committee Meeting in August

...s seeking approval for prevention and treatment of postmenopausal osteoporosis and prevention and treatment of bone ...ons of treatment and prevention of osteoporosis in postmenopausal women, and treatment and prevention of bone loss i...udied in a range of bone loss conditions including postmenopausal osteoporosis and bone loss in patients undergoing ...

Vermillion, Inc. Files a Voluntary Petition for Reorganization Relief Under Chapter 11 of the United States Bankruptcy Code

...proprietary OvaCalc algorithm to estimate the risk of malignancy in pre and postmenopausal women who were scheduled for surgery with an ovarian mass. The data demonst...g a greater than 90% negative predictive value among both premenopausal and postmenopausal patients. About Ovarian Cancer Commonly known as the "silent k...

Bionovo Announces Publication of Positive Phase 2 Trial Results for Menerba(TM)

...r uterine cancers. This Phase 2 trial of Menerba provided evidence that treatment with Menerba is effective for the treatment of hot flashes in postmenopausal women and the drug is very well tolerated without any significant side effects. "I am very encouraged and pleased by the findings of this clini...

FDA Accepts Amgen's Submission and Files Biologics License Application for Denosumab

...BLA) for denosumab, an investigational RANK Ligand inhibitor. The indications for which Amgen is seeking FDA approval are treatment and prevention of postmenopausal osteoporosis (PMO) in women and treatment and prevention of bone loss in patients undergoing hormone ablation therapy for either prostate or breast ca...

Amgen's Fourth Quarter 2008 Adjusted Earnings Per Share Increased 6 Percent to $1.06; Full Year 2008 Adjusted Earnings Per Share Increased 6 Percent to $4.55

...(FDA) for denosumab, an investigational RANK Ligand inhibitor. The indications for which Amgen is seeking FDA approval are treatment and prevention of postmenopausal osteoporosis (PMO) in women, and treatment and prevention of bone loss in patients undergoing hormone ablation for either prostate or breast cancer. T...

AIM Pharmakon (API) Announced a New Proprietary Premium-Quality Natural Concentrated Liquid Calcium and Mineral Supplement Now Available Direct to Consumers

...s to achieve peak bone mass, strong teeth, and prevents the bone loss. AimCa++DONAN is ideal for athletes, women concerned with menopause in peri- and postmenopausal phases, baby-boomers and seniors needing extra calcium supplementation. "The role of calcium in the pathogenesis of osteoporosis is significant...

Genomic Health to Present Multiple New Studies at 31st Annual San Antonio Breast Cancer Symposium

..., 2008, 10 a.m. - 10:15 a.m. Abstract #53 Oral presentation (General Session 5): "Risk of distant recurrence using Oncotype DX in postmenopausal primary breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study" Presenter: Mitch Dowsett, Ph.D., Royal Marsden ...

Genomic Health Announces Third Quarter 2008 Financial Results and Business Progress

...cepted for oral presentation at the San Antonio Breast Cancer Symposium in December 2008: -- "Risk of distant recurrence using Oncotype DX in postmenopausal primary breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study" -- "GRB7-dependent pathways are potentia...
Postmenopausal in Biological Definition

Nutrition

...y-related health risk. Am J Clin Nutr. 2004 Mar;79(3):379-84. J Mei, SSC Yeung et al "High dietary phytoestrogen intake and bone mineral density in postmenopausal women."Journal of Clinical Endocrinology and Metabolism, 2001, Vol 86, Iss 11 Merritt JC "Metabolic syndrome: soybean foods and serum lipids."J Natl...
Postmenopausal in Biological Dictionary

Estrogen

... Estrogens (alternative spellings: oestrogens or Ĺ“strogens) are a group of ... These secondary sources of estrogen are especially important in postmenopausal women. ... Learn about proper hormonal balance, estrogen dominance, progesterone cream, fibroid tumors, endometriosis, and more. ... Estriol is...
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