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Porphyria in Medical News

QLT announces 12-month results from Novartis sponsored MONT BLANC study evaluating standard-fluence Visudyne(R) combination therapy

... than the standard light dose used in this study. After treatment, patients should avoid direct sunlight for five days to prevent sunburn. People with porphyria should not be treated with Visudyne. About QLT QLT Inc. is a global biopharmaceutical company dedicated to the discovery, development and co...

QLT announces positive results from the evaluation of Visudyne(R) combination therapy

...ed to lower light doses being used in this study. After treatment, patients should avoid direct sunlight for five days to prevent sunburn. People with porphyria should not be treated with Visudyne. About QLT QLT Inc. is a global biopharmaceutical company dedicated to the discovery, development and co...

QLT announces interim results of radical study evaluating Visudyne combination therapy

...ed to lower light doses being used in this study. After treatment, patients should avoid direct sunlight for five days to prevent sunburn. People with porphyria should not be treated with Visudyne. About QLT QLT Inc. is a global biopharmaceutical company dedicated to the discovery, developmen...

New book by UCR biologist discusses 12 diseases that impacted humanity

...he book , Sherman argues that the following dozen diseases shaped history and illuminated the paths taken in finding measures to control them: porphyria and hemophilia , which influenced the political fortunes of England, Germany, Russia and the United States Late blight , which spawned a wave of...

ABCB6 Is Key to Production of Heme in Hemoglobin

...hat triggers pain in the chest, abdomen, limbs or back, as well as paralysis, cramping and personality changes or mental disorders. 'Also, people with porphyria can suffer sudden, acute attacks if they take certain tranquilizers and other drugs that interfere with this system,' Schuetz said. 'So our work contr...

Colour Of Urine Can Reveal The Health Status Of The Patients

...ages. And gout can produce pink urine. This diagnostic tool goes back many centuries. The ancient Greeks first diagnosed the rare blood disorder porphyria by observing colourful urine and even named the illness after the Greek word for purple. Then in the Middle Ages, when urine analysis enjoyed it...

Study Unveils New Insight To The Madness Of King George III

...the journal Cell that the nutritional component of porphyria involves a key master metabolic molecule, PGC-1 al...ge III’s hair contained arsenic, which can provoke porphyria attacks. PGC-1 alpha is a “transcriptional c...yria. The findings suggest that patients with porphyria should avoid any drugs or foods that turn on PGC-1...

Arsenic May Have Been Responsible For The Madness Of King George III Of England

...and contamination of his antimonial medications is the probable source of the arsenic. We propose that exposure to arsenic would exacerbate attacks of porphyria in a genetically predisposed individual. King George III was diagnosed to have suffered from Porphyria- a genetic defect leading to the faulty sy...
Porphyria in Medical Technology

AMT Receives EMEA Orphan Drug Designation for Acute Intermittent Porphyria

AMSTERDAM, May 28 /PRNewswire-FirstCall/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, announced today that the European Medicines Agency has granted Orphan Drug Designation to AMT's gene therapy product AMT-021 for the treatment of acute int...

Amsterdam Molecular Therapeutics BV to present preclinical proof-of-concept data on its gene therapy AMT-020 to treat acute intermittent porphyria

The research, done in collaboration with the Centro de Investigación Médica Aplicada (CIMA) at the University of Navarra, Pamplona, Spain, is being presented at Porphyrins and Porphyrias Congress, Rotterdam, the Netherlands. AMSTERDAM, the Netherlands, May 1st 2007 - Amsterdam Mole...
Porphyria in Medical Products

Acute Intermittent Porphyria Enzyme

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Porphyria in Medical Dictionary

Porphyria

Patients with acute porphyria (PCT, AIP, HCP, VP) are at increased risk over ... Porphyria is diagnosed through spectroscopy and biochemical analysis of blood, ... Discusses the types, causes, symptoms, diagnosis, and treatment of porphyria . ... Each type of porphyria is due to ...

Acute porphyria

The acute , or hepatic, porphyrias primarily affect the nervous system, resulting ... Patients with acute porphyria (PCT, AIP, HCP, VP) are at increased risk over ... Acute intermittent porphyria (AIP) is a rare autosomal dominant metabolic disorder affecting the production o...

Systemic

...formation management, with a special focus on large-scale long term program evaluation and assessment. ... signs of systemic disease. Variegate porphyria ... (reaction to light), systemic symptoms arising from neurological problems, or both. ... Systemic symptoms ... Pronunciation of systemic ...

Porphyrias

... does Porphyrias mean? ... Porphyria's Lover. porphyria , acute intermittent. porphyria , acute intermittent ... In erythropoietic ...tionary and glossary with medical definitions ... porphyria is derived from the Greek word " ... All forms of...

Gene

... gene provides instructions for producing a protein that is located on ... Researchers suspect that HFE gene mutations may trigger this type of porphyria ... Sometimes not enough is known about a gene to assign it to an established family. ... No formal guidelines define the criteria for grouping...
Porphyria in Biological News

ABCB6 is key to production of heme in hemoglobin

...hat triggers pain in the chest, abdomen, limbs or back, as well as paralysis, cramping and personality changes or mental disorders. "Also, people with porphyria can suffer sudden, acute attacks if they take certain tranquilizers and other drugs that interfere with this system," Schuetz said. "So our work contr...

Attacks of King George III's madness linked to key metabolism molecule

...C-1 mediates effects of nutrition on blood disease porphyria Dana-Farber Cancer Institute researchers say th...26 issue of Cell that the nutritional component of porphyria involves a key master metabolic molecule, PGC-1 al...hin, PhD, is lead author. "We've explained how porphyria symptoms can occur in episodic attacks triggered b...
Porphyria in Biological Technology

Amsterdam Molecular Therapeutics Reports Full Year Results 2007

...e-registration trial in Canada on track - Appointment of Ferdinand Verdonck as chairman of supervisory board. - Global rights for acute intermittent porphyria treatment - Exclusive license to all gene therapy products from CIMA - Agreement with CIMA/Digna Biotech for AAV-mediated IGF-I treatment of late ...

Amsterdam Molecular Therapeutics Reports Half Year Results 2007

...- Appointment of Ferdinand Verdonck as chairman of supervisory board. - Global rights for our product AMT 020 for the treatment of acute intermittent porphyria Results comparison Total revenues for the six months ended June 30, 2007, were EUR 50,000 compared to EUR 208,000 for the same period in 2006. The d...
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