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Porphobilinogen in Medical News

Could new discovery about a shape-shifting protein lead to a mighty 'morpheein' bacteria fighter?

...ithin living cells. The researchers discovered a small molecule, which they have named morphlock-1, binds the inactive form of a protein known as porphobilinogen synthase (PBGS), an enzyme used by nearly all forms of cellular life. The functioning form of PBGS is built from eight identical component parts in w...
Porphobilinogen in Medical Technology

Amsterdam Molecular Therapeutics BV to present preclinical proof-of-concept data on its gene therapy AMT-020 to treat acute intermittent porphyria

...suffering from recurrent porphyria attacks and/or neuropathy. AMT-020 is comprised of an Adeno-Associated Virus (AAV) vector delivering the gene for porphobilinogen deaminase (PBGD). The aim of this study, which was performed by Dr's Fontanellas, González-Aseguinolaza and Prieto at CIMA, was to investigate ...
Porphobilinogen in Medical Products

Porphyrins & Porphobilinogen (PBG), Urine

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Porphobilinogen in other areas

Porphobilinogen - Wikipedia, the free encyclopedia

cytosolic: Porphobilinogen · Hydroxymethylbilane · Uroporphyrinogen III ... Retrieved from "http://en.wikipedia.org /wiki/ Porphobilinogen" ...

Porphobilinogen synthase - Wikipedia, the free encyclopedia

Porphobilinogen synthase synthesizes porphobilinogen through the asymmetric condensation of two molecules of aminolevulinic acid. All natural tetrapyrroles, including hemes, chlorophylls and vitamin B12, share porphobilinogen as a common precursor.

Porphobilinogen: Definition from Answers.com

porphobilinogen An intermediary product in the biosynthesis of heme. ... What are the common interfering substances for porphobilinogen assay? ...

Acute Intermittent Porphyria: Porphyrias: Merck Manual Home Edition

... delta-aminolevulinic acid and porphobilinogen initially in the liver. ... Most people with a deficiency of porphobilinogen deaminase never develop symptoms. ...

Porphobilinogen Synthase

Porphobilinogen Synthase: A Novel Specific Inhibitor of Tetrapyrrole Biosynthesis in Plants ... Porphobilinogen synthase (PBGS) is a key enzyme in the biosynthesis of ...

Heme Synthesis

Synthesis of d-aminolevulinate & porphobilinogen ... PBG Synthase (Porphobilinogen Synthase), also called ALA Dehydratase, catalyzes ...
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