Beyond lithium for bipolar disorder
While lithium treatment has proven to be a godsend for many of the two million Americans with bipolar disorder, it is not without its downside. People on the drug may develop hypothyroidism, tremors, cognitive impairment, and excessive thirst and urination and gain weight. However, better treatments for bipolar disorder depend on a better understanding of the still-mysterious mechanism by...Field of beams - Novel system uses polarized light pulses to reveal crop health
Mathematical models have become invaluable decision-making tools for public health officials. As demonstrated during the United Kingdom's foot-and-mouth epidemic of 2001, models can be useful in two ways: they can reveal the underlying characteristics of an infection and they can allow the comparison of alternative control measures. Often, however, such models make implicit assumptions that may s...Clock molecule's sensitivity to lithium sheds light on bipolar disorder
Researchers at the University of Pennsylvania School of Medicine discovered that a key receptor protein is a critical component of the internal molecular clock in mammals. What's more, this molecule –called Rev-erb?is sensitive to lithium and may help shed light on circadian rhythm disorders, including bipolar disorder. The findings, which also provide insight into clock-controlled aspects of met...Scientists to employ Arctic ice and polar bears to protect diversity of world's crops
Scientists at St. Jude Children's Research Hospital have announced that a vaccine they developed a few years ago against one antigenic variant of the avian influenza virus H5N1 may protect humans against future variants of the virus. Vaccines based on this model might therefore be suitable for stockpiling for use during a pandemic (worldwide epidemic) until a new vaccine could be developed specif...Scientists use an 'ice lolly' to find polar bacteria in their own backyard
To study the bacteria which survive in extreme cold, scientists no longer have to go to extreme environments, such as Antarctic lakes and glaciers. Bacteria previously isolated from polar climates, and have properties which allow them to survive in extreme cold, have been isolated from soil in temperate environments. Professor Virginia Walker and her colleagues at Queen's University, Canad...Complete 2 channel polarographic oxygen monitoring system from Instech Solomon
Description:The SYS203 is a complete, flexible system designed specifically for oxygen measurement in small samples, as is frequently required in biological research. The system is designed around Instechs miniature Clark-style polarographic electrode. Measuring only 1/8 of an inch in diameter (3.2 mm), it is ideal for metabolic studies of mitochondria, cell suspensions, and enzyme assays....PolarScreen Androgen Receptor Competitor Assay Kit, Red from Molecular Probes (Invitrogen)
Description:The PolarScreen Androgen Receptor (AR) Competitor Assay Kits provide a sensitive and efficient method for studying and screening potential AR ligands using fluorescence polarization (FP). The kits contain rat AR ligand binding domain protein tagged with His and GST [AR-LBD (His-GST)], and a novel, selective fluorescent androgen ligand (Fluormone AL Green in the green assay kit or Fluormone AL Red...PolarScreen Progesterone Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)
Description:PolarScreen Progesterone Receptor (PR) Competitor Assay Kits are ideal for studying or screening novel progesterone receptor binding compounds using fluorescence polarization (FP). The homogenous assay utilizes a fusion of glutathione transferase to the ligand binding domain of human progesterone receptor [PR-LBD(GST)] and a proprietary, fluorescently tagged progesterone ligand, Fluormone PL Gree...PolarScreen Glucocorticoid Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)
Description:PolarScreen Glucocorticoid Receptor (GR) Competitor Assay Kits are ideal for studying or screening novel GR binding compounds. The PolarScreen GR Competitor Assay Kits contain partially purified GR protein, stabilizing peptide, buffer, and one of the following proprietary fluorescent glucocorticoid Fluormone ligands: GS1 (green assay kit), GS Red (red assay kit), or GS Far Red (far red assay kit)...PolarScreen PPARGamma-Competitor Assay Kit, Red from Molecular Probes (Invitrogen)
Description:The PolarScreen Peroxisome Proliferator-Activated Receptor-gamma (PPARGamma) Competitor Assay Kits provide a sensitive and efficient method for studying and screening potential PPARGamma ligands using fluorescence polarization (FP). The kit contains human PPARGamma-Ligand binding domain (PPARGamma-LBD) with an N-terminal His-tag and a novel, selective fluorescent PPARGamma ligand: Fluormone PPARG...Receptor Binding Assays using Fluorescence Polarization Detection: the [FP]2TM Characterized Tracers
. The process is typically highly automated and can provide screening rates over 100,000 samples in a 24 hour period. To achieve this, assays must be simple, p...cAMP DataFile: Homogenous Cyclic AMP detection using High Efficiency Fluorescence Polarization
A Sensitive, Robust, Homogenous, and Rapid Assay Uses High Efficiency Fluorescence Polarization (HEFP) detection method Detects pmol amounts of cAMP Optimized for cell extract and enzyme preparations Requires no separation or wash steps Available in a kit and in bulk packaging ...Immunoassay of Theophylline by fluorescence polarisation
Fluorescence immunoassay is applied to the detection of theophylline, a drug used for myocardial stimulation. Interference from other sample components is limited by use of polarization measurements, which discriminate between bound and unbound fluorophores. The detection system includes a T-format sampling module mounting two emissio...Survey shows how bipolar disorder affects the quality of life for patients
A global survey on bipolar disorder conducted by the World Federation for Mental Health reveals that patients of the // disease feel that their quality of life suffers because of their disease. Bipolar disorder is a psychotic disorder characterized by successive feelings of elation and depression. Also known as manic-depressive illness that affects 3 to 4 5 of the global adult populati...Single drug for bipolar disorder
Researchers have pointed out that on a short term a single drug may be used to treat both the phases of bipolar disorder //. Bipolar disorder is a psychotic disorder characterized by successive feelings of elation and depression. Also known as manic-depressive illness that affects 3 to 4 5 of the global adult population. This is a chronic condition and most of the sufferers have multi...Psychosocial Disability Varies In Accordance With Bipolar Symptom Changes
A decrease or increase in psychosocial disability in patients who suffer from bipolar disorder has been noticed with every decrease or increase in their depressive symptom severity//. This has been revealed in the December 2005 issue of the Archives of General Psychiatry. Bipolar disorder is associated with suicidal behavior, and cycles of mania, abnormal elation, and depression are characterized...Seroquel to Treat Depression In Case Of Bipolar Disorder
AstraZeneca the Head of the Anglo-Swedish Company has come out with the results of the drug Seroquel stating that it be used in the treatment of // both maniac behaviour and mental depression in people suffering with bipolar disorders. He has asked US to consider his drug as a sole treatment for maniac and depression symptoms related to bipolar disorder. AstraZeneca, the dr...Disposable Bipolar Pencil - 18 Gauge Curved
Description:18 gauge curved. Fine tip. Lightweight design offers precise hemostasis. Pencil design minimizes tissue trauma and induced astigmatism. Knurled handle provides a sure grip and better manipulation....Disposable Bipolar Pencil - 18 Gauge Straight
Description:18 gauge straight. Fine tip. Lightweight design offers precise hemostasis. Pencil design minimizes tissue trauma and induced astigmatism. Knurled handle provides a sure grip and better manipulation....Disposable Bipolar Pencil - 23 Gauge Tapered Tip
Description:18 gauge tapered fine tip. Lightweight design offers precise hemostasis. Pencil design minimizes tissue trauma and induced astigmatism. Knurled handle provides a sure grip and better manipulation....McPherson Straight Bipolar Forceps
Description:Straight shafts with 4 mm jaws. Serrated handle with dull finish. Jaws straight....Bipolar Disorder in Children Difficult to Diagnose, Reports the Harvard Mental Health Letter
BOSTON, April 25, 2007 /PRNewswire-USNewswire/ -- At leastone-third of the time, the symptoms of bipolar disorder firstappear in childhood or adolescence. However, in children, it can bedifficult to distinguish bipolar symptoms from those of otherdisorders, notes the May 2007 issue of the Harvard Mental HealthLetter. Children, especially young children, usually do not show theadul...UCLA: Lithium Builds Gray Matter in Bipolar Brains, UCLA Study Shows
Novel brain imaging technique suggests how lithium works as atherapeutic LOS ANGELES, April 12, 2007--Neuroscientists at UCLA have shownthat lithium, long the standard treatment for bipolar disorder,increases the amount of gray matter in the brains of patients withthe illness. The research is featured in the July issue of the journalBiological Psychiatry and is curren...Latest NIMH Study on Bipolar Disorder
Statement of Ken Duckworth, M.D., Medical Director NationalAlliance on Mental Illness (NAMI) ARLINGTON, Va., April 02, 2007 /PRNewswire-USNewswire/ -- Todaythe Archives of General Psychiatry published a study on theeffectiveness of psychosocial treatments for bipolar disorder,"Psychosocial Treatments for Bipolar Disorder." This is a follow upstudy to one released last Thursday in the New...Study Sheds Light on Medication Treatment Options for Bipolar Disorder
BETHESDA, Md., March 29, 2007--For depressed people with bipolardisorder who are taking a mood stabilizer, adding an antidepressantmedication is no more effective than a placebo (sugar pill),according to results published online on March 28, 2007 in the NewEngland Journal of Medicine. The results are part of thelarge-scale, multi-site Systematic Treatment Enhancement Programfor Bipolar D...