New Drug, Pleconaril speeds recovery from common cold
Colds are the single most frequent reason why people go to the doctor. Antibiotics are worthless against colds, though doctors often prescribe them anyway. Researchers have developed a drug that speeds recovery from the common cold -- a significant breakthrough for scientists who have been in pursu...FDA panel refuses anti-viral cold remedy
...e most common cause of the common cold. In clinical studies, the drug eased symptoms and cut the duration of colds by about a day. One concern is that pleconaril tablets must be taken within 24 hours of the first symptoms, making the drug's real-life usefulness questionable. Because colds are not serious illnes...Pleconaril - Wikipedia, the free encyclopedia
Pleconaril is an antiviral drug being developed by Schering-Plough for prevention of asthma exacerbations and common cold symptoms in asthmatic subjects exposed to picornavirus respiratory infections. Although the formulation used by Schering-Plough is a nasal spray,...Pleconaril for Treatment of the Common Cold? - February 1, 2004 ...
In November 2003, ViroPharma licensed pleconaril to Schering-Plough, who are ... Efficacy and safety of oral pleconaril for treatment of colds due to ...Mutation in Enterovirus 71 Capsid Protein VP1 Confers Resistance to the ...
Pleconaril, one of the WIN compounds with capsid-binding capability targeting ... However, pleconaril did not neutralize the cytopathic effect (CPE) induced by ...Pleconaril Enteroviral Sepsis Syndrome - Full Text View ...
The effects of pleconaril on measures of clinical outcome also will be evaluated. ... enterovirus, enteroviral sepsis, Pleconaril, infants ...Pleconaril Attenuates Cold Symptoms
PLECONARIL ... Pleconaril treatment significantly reduced viral RNA titers in ... "In laboratory studies, pleconaril is active only against ...