Molecule plays early role in nonsmoking lung cancer
COLUMBUS, Ohio The cause of lung cancer in never-smokers is poorly understood, but a study led by investigators at the Ohio State University Comprehensive Cancer Center and at the National Cancer Institute has identified a molecule believed to play an early and important role in its development. ...Penn State plays integral role in $35 million stress project
How employees manage stress at work and in their homes is the focus of Penn State's portion of a $35 million National Institutes of Health grant that will also test the efficacy of a workplace intervention designed to reduce employee stress and promote well-being. "We're seeing that stress in th...Family History Plays Key Role in Blood Clot Risk
Study finds odds more than doubled, especially if kin was diagnosed at young age MONDAY, March 23 (HealthDay News) -- Children and siblings of people who develop blood clots in the veins may be more than twice as likely as those without a family history to develop the condition, Dutch ...Exercise plays large role in recovery from knee replacement and the occurrence of osteoarthritis
Two new studies found that exercise may be a factor in recovering from a total knee replacement (total knee arthroplasty or TKA) and knee osteoarthritis (OA). One study involving a progressive quadriceps strengthening program after total knee replacement found that it enhanced clinical improvement...Gene plays dual role in breast cancers with poor prognosis
A new study reveals that the metadherin gene (MTDH) plays a role in both cancer metastasis and resistance to chemotherapy. The research, published by Cell Press in the January 6th issue of the journal Cancer Cell , identifies MTDH as a promising therapeutic target for high risk breast cancers. ...PTSD Associated With Higher Alzheimer's/Dementia Risk; Moderate Alcohol Consumption May Lower it
...rans with post-traumatic stress disorder (PTSD), and lower Alzheimer's risk among adults who consume moderate amounts of alcohol. "Your brain plays a critical role in almost everything you do: thinking, feeling, remembering, working, and playing - even sleeping," said Maria Carrillo, PhD, Director...Gene Findings Unlocking Reasons for Neuroblastoma Risk
... A second genome-wide study found that a copy number variation (CNV) -- a missing stretch of DNA -- along a structurally weak location on chromosome 1 plays an important role in the development of neuroblastoma. Although CNVs have received much attention from genetics researchers over the last several year...Cordex Signs European Development Partnership for ATPotent(TM) Sperm Motility Drug
...ubiquitous purine nucleotide found in every cell of the human body where it plays a critical role in cellular metabolism and constitutes the source of energy...by activating cell surface receptors called P2 receptors. Extracellular ATP plays an important role in sperm maturation in the male reproductive tract and is...WORLD'S First Robotic Assisted Kidney Transplant Performed at Saint Barnabas Medical Center
...n Medical School . A talented surgeon, he is a published author and has made several presentations at national surgical conferences. Dr. Geffner plays an active role in the community and is involved with "Live from Kidney Transplant," a series of live video telecasts of transplant surgery to high sch...3M Avagard D Instant Hand Antiseptic with Moisturizers
Description:... Hand antisepsis plays a significant role in preventing nosocomial infections and the associated morbidity, mortality and costs. 3M offers healthcare providers effective han...Scripps-led study shows ocean health plays vital role in coral reef recovery
The new research study led by scientists at Scripps Institution of Oceanography at UC San Diego suggests that by improving overall ocean health, corals are better able to recover from bleaching events, which occur when rising sea temperatures force corals to expel their symbiotic algae, known as z...Newly discovered gene plays vital role in cancer
[PRESS RELEASE, 27 February 2009] Gene p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously unknown gene, Wrap53, controls the activity of p53...NYU Langone Medical Center researchers find micro RNA plays a key role in melanoma metastasis
NEW YORK CITY (February 5, 2009)Scientists have long wondered how melanoma cells travel from primary tumors on the surface of the skin to the brain, liver and lungs, where they become more aggressive, resistant to therapy, and deadly. Now, scientists from NYU Langone Medical Center have identifi...Compromised skin barrier function plays a role in psorasis development
Researchers at the Genome Institute of Singapore (GIS) and the Anhui Medical University, China, have identified genes that play an important role in the development of psoriasis, a common chronic skin disease. The research, led by GIS Human Genetics Group Leader and Associate Prof. Liu Jianjun,...Queen's University Belfast plays leading role in Europe-wide tests for safer food
A top food scientist at Queen's University Belfast is playing a major role in a 4m European project to develop new techniques to detect chemical contaminants in food and animal feed. Professor Chris Elliott, Director of the Institute of Agri-Food and Land Use at Queen's, will lead a team of...Master gene plays key role in blood sugar levels
When mice that lack steroid receptor-2 (SRC-2) a master regulator gene called a coactivator fast for a day, their blood sugar levels plummet. If they go another day without food, they will die. The severity of the hypoglycemia (low blood sugar) was unexpected, said Dr. Bert W. O'Malley, chai...Midwest plays key role in developing new medical device companies
CHICAGO -Last week, we talked about the size and growth of the medical device industry and some of the key market segments. This week's column will focus on the leading players in this $100 billion industry. Before we comment on some trends from this table, here are a couple interestin...Midwest plays small role in VC investment, angel groups to the rescue
A few weeks ago, we talked about Venture Capital investments during 2005 in the biotech and medical device sectors, and how these investments compared against the general VC landscape. I also promised to provide you with information on U.S. Venture Capital investments by region and stage of devel...Plastics that convert light to electricity could have a big impact
... standard. Such testing can be accomplished using a very small tool called an atomic force microscope, which uses a needle similar to the one that plays records on an old-style phonograph to make a nanoscale image of the solar cell. The microscope, developed in Ginger's lab to record photocurrent, come...Rabbit Anti-SKAP55 Polyclonal Antibody, Unconjugated from ABR-Affinity BioReagents
Description:...of LFA1 and TCR ligation. TCR engagement induces the translocation of SKAP55 to lipid rafts, where the interactions with Fyn take place. CD45 also plays a very important role in SKAP55/TCR-mediated signaling. SKAP55 involvement in the TCR signaling pathway is the subject of current research in murine a...Glycoprotein Isolation Kit WGA from Pierce Biotechnology, Inc.
Description:... Glycosylation is a post-translational modification that plays an important role in biological functions, including immune regulation, inflammation, cell-to-cell adhesion, and cell signaling. Pierce Biotechnology ...Apoptosis Pathway SpliceArrays from ExonHit Therapeutics Inc.
Description:... Alternative Splicing plays an important role in the regulation of signaling pathways involved in apoptosis and cell death. Splice variants have been reported that affect both th...Mouse Anti-CDX-2 Monoclonal Antibody, Unconjugated, Clone CDX2-88 from BioGenex
Description:...omeobox family, is an intestine-specific transcription factor that regulates both proliferation and differentiation in intestinal epithelial cells. It plays an important role in triggering cells towards the phenotype of differentiated villus enterocytes as well as in the maintenance of the phenotype. Clone...Human Topoisomerase I Wild Type from Calbiochem
Description:...d negative supercoiled DNAs without the requirement of energy. In addition to DNA replication and transcriptional activation, DNA topoisomerase I also plays a major role in pre-mRNA splicing, cell cycle and other gene regulatory pathways during cell growth and development. Since Topo I can cause large amou...