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Mitochondrial DNA mutations play significant role in prostate cancer

Mutations in mitochondrial DNA (mtDNA) playan important role in the development of prostate cancer, according toresearch by scientists at Emory University School of Medicine and theUniversity of California, Irvine. The findings are published onlinethis week in the Proceedings of the National Academy of Sciences(PNAS). Mitochondrial DNA, which is separate from nuclear DNA, is foundin the hun...

Female sex hormones play a vital role in defense against sexually transmitted diseases

Two McMaster University studies, to be published in the Journal of Virology, show that sex hormones have a profound effect on susceptibility of female mice to the herpes simplex virus, type 2 (HSV-2 ), one of the most common sexually transmitted diseases. Charu Kaushic, assistant professor and supervisor of the studies, says the implication of this work is quite significant. "The research...

An HIV Protein Plays a Surprising Role in Gene Activation

Retroviruses are expert manipulators when it comes to co-opting their host's cellular resources. A great deal of human complexity stems from the vast repertoire of proteins and mechanisms dedicated to the business of regulating gene expression, and retroviruses like HIV have evolved myriad ways of redirecting that machinery to their own benefit. Humans and other eukaryotes have three type...

White blood cell waste disposal system plays critical regulatory role

A new research study identifies a critical inhibitory step that is a key component of the feedback circuit regulating the balance between neutrophil production and destruction. The research, published in the March issue of Immunity, suggests that the process for disposal of dying neutrophils is actively linked to neutrophil production. A clear understanding of the processes that control neutrophi...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

Gastric and colorectal cancers account for more than 1 million deaths worldwide every year and several research groups have been working to identify the molecular events that result in the initiation and progression of these tumors. It has been established that interfering with the function of one gene, called Adenomatous Polyposis Coli (APC) has a profound effect on the cells lining the innermos...

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Ph.D. Peptide Display Cloning System from New England Biolabs

Description:The Ph.D. Peptide Display Cloning System facilitates the display of custom peptide libraries on the surface of bacteriophage M13 as coat protein fusions, creating a physical linkage between each displayed peptide and its encoding DNA sequence. Peptide ligands for a variety of targets can then be selected by the straightforward method of biopanning. The supplied display vector M13KE is an M13 deri...
Company:New England Biolabs

pYD1 Yeast Display Vector from Invitrogen

Description:The pYD1 Yeast Display Vector is specifically designed to target and display recombinant proteins on the surface of Saccharomyces cerevisiae. Displayed proteins can be analyzed for their ability to interact with known or putative ligands. pYD1 uses the a-agglutinin yeast adhesion receptor which consists of two domains, Aga1 and Aga2, to display recombinant protein on the surface of S. cerevisiae....
Company:Invitrogen

Phage Display cDNA Library Screening Kit from Spring Bioscience

Description:Spring offers a large collection of phage display libraries, human adult tissues, fetal tissuea, cell lines, and mouse tissues. All cDNA libraries are constructed in pHD9 vector. The size of cDNA inserts has been verified to be from 200bp to 1000bp by gel electrophoresis of DNA prepared from the amplified libraries....
Company:Spring Bioscience

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Fractionating DNA Fragments Generated by Differential Display PCR

Pfizer Central Research, Sandwich, UK. 01304 618482 Differential display PCR (DDPCR) is a widely used technique foridentifying genes differentially expressed between cell types. Application ofDDPCR to allergic disease provides a potential means for elucidating themechanisms involved in allergic...

Flat panel displays

One of the fastest-growing segments of the semiconductor industry is concerned with a new generation of graphic displays for communications and high-definition television sets. For phosphors that might be used as the active medium in such displays, the critical characteristics are the lifetimes and wavelengths of their emissions....

To be a player in the "Knowledge Economy," Wisconsin needs more tech workers

Wisconsin's assets in the 21st century knowledge economy are impressive when compared with other states of its size. But its weaknesses are intimidating, especially when it comes to training and retaining a skill...

Getting noticed in Genetown: Wisconsin biotech on display

That's not the case in...

Podcasts time, place, and player shifted media

Podcasts are becoming increasingly popular am...

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Medias Plays Vital Role In Sexual Behavior Of Teenagers

According to Pediatrics journal, a new study states that teenagers who use the media with high sexual content have twice the chance to have sex by the time they are 16 than// those kids who use the media lesser. There seems to be a marked increased of sexual activity among the teenagers between 12 and 14, who are more exposed to media. Researchers at the University of North Carolina at...

Diet plays a role in kidney stones

According to a few researchers, lessening calcium in the diet does not help prevent the return of kidney stones. Kidney stones are made of a chemical called calcium oxalate and one approach to preventing this painful condition// is to reduce the amount of calcium in the diet. But since calcium is important for keeping a healthy level of bone density and controlling blood pressure, there n...

Treadmill test displays hidden heart disease

Researchers at Hopkins University have found that treadmill testing is a useful way of pinpointing those at risk of heart problems. Many people who develop// heart disease have no obvious symptoms like chest pain or breathlessness. According to researchers, treadmill testing can show up hidden weaknesses long before heart problems become obvious. They report on a study of nearly 2,000...

Clotting Protein plays a role in nerve repair

According to a new study, fibrin, a protein that helps form blood clots, may also be involved in regulating the repair of nerve damage. The discovery could lead to new strategies for repairing diseases of the nervous system, such as multiple sclerosis, although the research is still on the basic science level.// In multiple sclerosis, the slow destruction of myelin--the thin, protecti...

Heart patients should play Golf

Researchers have observed that, people suffering from heat diseases are better off playing golf which provides safe and effective exercise, but for a few it might prove too much.People who are diagnosed with heart problems may wonder if it is still safe to enjoy a game of golf.// Researchers at the Hopkins University have now addressed this question. They followed 15 male golfers, aged b...

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Near PT Test Card/Child Recog/Playing Cards - BC2207

Description:Near PT test card/child recog/ playing cards 5 1/2" X 8"....
Company:Bernell

MDS Inc Display System

Description:MDS display system provides maximum impact for the marketing of optical frames and products. This unique approach to displaying frames allows your retail area to maximize frame attributes and create appealing, flexible and eye-catching displays. The products are shown at their best and your patients are motivated. Removable holders. Variable number of frames displayed (on a typical 48" x 48" pane...
Company:Modular Design Systems Inc.

1 Frame Eye Vee 2.0 Clear Display

Description:1 Frame clear base post with transparent Eyevee 2.0 Clip....
Company:Delectable Display

12 Frame Locking Rod Display

Description:Stainless steel lockable wall display for up to 12 frames....
Company:Delectable Display

The Wiggler Display

Description:69" 5 shelves electric rotating display with gunmetal grey frame. Lead time 6-8 weeks....
Company:Delectable Display

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Aeolus Pharmaceuticals' AEOL 10113 May Play an Important Role Regulating the Oxidative Damage Induced by Ionizing Radiation

LAGUNA NIGUEL, Calif.--(BUSINESS WIRE)--Apr 23, 2007 - AeolusPharmaceuticals, Inc. (OTCBB:AOLS) announced the presentation ofdata by researchers at Loma Linda University Medical Center showingthat one of the Company's metalloporphyrin antioxidants, AEOL10113, may play an important role regulating the oxidative damageinduced by ionizing radiation. Radiation therapy is used alone or in comb...

MedImmune Publishes New Data in Nature Immunology Demonstrating The Role HMGB1 May Play in Systemic Autoimmune Diseases

- Preclinical Data Support Rationale for Targeting Pro-InflammatoryProtein - GAITHERSBURG, Md., April 18, 2007 /PRNewswire-FirstCall/ --MedImmune, Inc. today announced the publication of preclinicalstudy data demonstrating a role for high mobility group boxprotein-1 (HMGB1), a nuclear DNA-binding protein, in the pathologyof systemic autoimmune diseases such as systemic lupuserythematosus...