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Photoreceptors in Medical News

The ABC Of Photoreceptors In The Eye

Researchers at the University of Michigan Kellogg Eye Center have been able to observe how an embryonic retina cell develops into a mature one and then goes about doing the task assigned to it.// Scientists were able to catch the cell when it had been assigned a particular task, but had not yet beg...

Developing gene therapy to fight blindness

...ust outside the retina that closely interacts with photoreceptors in the maintenance of visual function. Patients w...ult of this defect, debris accumulates between the photoreceptors and retinal pigment epithelium, resulting in death of photoreceptors and loss of vision. The researchers plan to de...

Stemedica Discovers Significant Breakthrough in the Use of Stem Cells and Stem Cell Factors for the Treatment of Retinal Degeneration

...E stem cells injected into the suprachoroidal space prevented the animal's RPE cell's degeneration as well as preventing degeneration of the overlying photoreceptors proven by very objective ERG testing and histopathology. Secondarily, and even more interesting, is that the fellow contra lateral eye also showed a b...

New Insight Into Primate Eye Evolution

...aking them effective for nighttime vision. The owl monkey's nocturnal retina is also larger and lacks a fovea, the central region of high-density cone photoreceptors that gives the diurnal eye high acuity and daytime color vision. For both owl and capuchin monkeys, the specialized cell types in the eye all dev...

Sirion Therapeutics Announces Positive Results From Interim Analysis of Phase II Trial and Receives FDA Fast Track Designation for Fenretinide

... vision loss in conditions such as GA. About Geographic Atrophy Geographic atrophy (GA) is characterized by confluent areas of cell death in photoreceptors and retinal pigment epithelium (RPE). GA is bilateral in more than half of afflicted patients and largely the cause of legal blindness from age-relate...

Eye Cells Believed to Be Retinal Stem Cells Are Misidentified

...less, the previous finding was met with a tremendous amount of enthusiasm because of the promise of introducing these cells into the eye to regenerate photoreceptors lost to blindness." In their studies, Dyer and his colleagues analyzed the sphere-forming cells in detail to determine whether they were really ...

3-D snapshots of eyes reveal details of age-related blindness

... between the layers of the retina. 3-D OCT provides a more accurate estimate of the volume of fluids leaked by these faulty vessels, which damages the photoreceptors in the eye and leads to blindness. The MIT group is publishing the electronic data in these 3-D images in order to make it available to the image ...

'Dark cells' of living retina imaged for the first time

... they are exposed to light, Williams explains. The photoreceptors contain molecules called photopigments. When light...e photopigment molecules and send them back to the photoreceptors to start the process again. In addition, the RPE layer keeps the photoreceptors healthy by collecting and storing toxic waste prod...

Taurine: Key to the visual toxicity of an anti-epileptic drug for children?

...cy of the organism in taurine (amino acid) triggers the degeneration of the photoreceptors (cells of the retina converting light into nervous signals), the researcher... in the plasma. This marked fall is responsible for the degeneration of the photoreceptors and thus for the retinal toxicity in the animals exposed to light. Pendin...

Team led by Scripps Scientists increases understanding of two types of blindness

...ce the risk of developing bleeding from the more common type of neovascular macular degeneration in humans, but the concept of maintaining functioning photoreceptors in the face of continuing vascular abnormalities has not been shown previously." An Attractive Alternative The second option the group explore...
Photoreceptors in Medical Technology

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting

...n pathway by Palomid 529 may be neuroprotective to photoreceptors and perhaps represents a novel therapy for other r..., a condition that can prevent the regeneration of photoreceptors following successful retinal reattachment surgery....suggest that Palomid 529 may be neuroprotective to photoreceptors and reduce the incidence of subretinal fibrosis wi...

Pregnant Women Need Omega-3 to Boost Infant Development

...cord is a good indicator of intra-uterine exposure to omega-3s during the last trimester of pregnancy, a crucial period for the development of retinal photoreceptors and neurons," said study supervisor Dr. Eric Dewailly.** After testing the infants at six and 11 months, the researchers discovered visual acuity, c...
Photoreceptors in Medical Dictionary

Retinitis pigmentosa

...sa is a disorder in which the cells in the eye that sense ... Retinitis pigmentosa (RP) is a rare, hereditary disease that causes the rod photoreceptors in the retina to gradually degenerate. Retinitis pigmentosa is a term that refers to group of hereditary disorders that affect the retina?s ...

Cone

...op: right circular cone bottom: cones and rods of a human eye (Academy Artworks) (Precision Graphics) cone n cone cell n. One of the photoreceptors in the retina of the eye that is responsible for daylight and color vision; they are densely concentrated in Formulas for finding the height, ...
Photoreceptors in Biological News

Tips from the American Journal of Pathology

...kernagel M, Odermatt B, Samardzija M, Reichenbach A, Grimm C, Rem C: Cooperative phagocytes: resident microglia and bone marrow immigrants remove dead photoreceptors in retinal lesions. Am J Pathol 2009, 174: 2310-2323 ...

Eye cells believed to be retinal stem cells are misidentified

...less, the previous finding was met with a tremendous amount of enthusiasm because of the promise of introducing these cells into the eye to regenerate photoreceptors lost to blindness." In their studies, Dyer and his colleagues analyzed the sphere-forming cells in detail to determine whether they were really re...

Cats' eye diseases genetically linked to diseases in humans

...found in the eye's retina that is capable of phototransduction, or the process by which light is converted into electrical signals. The changes in the photoreceptors result in cell death, which lead to blindness. "Cats are excellent models because they have relatively large eyes that are comparable to those ...

Seasonal affective disorder may be linked to genetic mutation, study suggests

...rom many mutations, and we have found one that has a clear link." The melanopsin gene encodes a light-sensitive protein that is found in a class of photoreceptors in the retina that are not involved with vision, but are linked to many non-visual responses, such as the control of circadian rhythms, the control of...

Gene therapy restores vision to mice with retinal degeneration

...H team used the standard viral vector adeno-associated virus to deliver the gene encoding melanopsin throughout the retinas of mice whose rod and cone photoreceptors had degenerated from lack of a crucial protein. Four weeks after delivery of the gene, melanopsin normally produced in 1 percent of retinal gangli...

Atomic-resolution views suggest function of enzyme that regulates light-detecting signals in eye

...l to the way light entering the retina is converted into a cascade of signals to the brain. This particular form of the enzyme comes from the cone photoreceptors of the retina and has not been well-researched, in contrast to its rod form. Rods are involved in night vision and motion sensation; the cones are res...

Biologists identify genes controlling rhythmic plant growth

...lar level." The scientists said these disparate genes act together to regulate rhythmic plant growth much like a gate with its hinges controlled by photoreceptors and the biological clockopening in the predawn hours to allow a wave of multiple plant growth hormones to act within the cells, then closing the gate ...

A model photochemical compass for bird navigation

...ively, they are not completely understood. One existing theory is that photoreceptors in a bird's retina absorb light, which causes a chemical reaction that, in .... The photoreceptor theory is supported by the fact that blue light photoreceptors have been detected in retinas of migratory birds when they perform magnetic...

NYU scientists set stage for understanding how color vision is processed

...of color vision, which requires comparison between photoreceptors that are sensitive to different wavelengths of lig...rosophila, color vision is achieved by specialized photoreceptors that contain different rhodopsins, the photopigmen...osophilas medulla--the brain structure where color photoreceptors project--focusing on neurons likely to be involved...

Mantis shrimp vision reveals new way that animals can see

...nimals would use it for something. Using it required the stomatopods to evolve a kind of filter in their eyes oriented at a precise 45 degree angle to photoreceptors underneath that pick up on linearly polarized light. The filter turns the circularly polarized light into its linear form. Many animals make use of li...
Photoreceptors in Biological Technology

Results From Neurotech's NT-501 Phase 2 Retinitis Pigmentosa Studies Demonstrate Consistent Biological Effect on Photoreceptors

LINCOLN, R.I., May 28 /PRNewswire/ -- Neurotech Pharmaceuticals, Inc. today announced that the Company's product candidate, NT-501, demonstrated a strong biologic effect in two Phase 2 clinical trials for retinitis pigmentosa (RP). RP is a slowly developing condition that causes the progressiv...

Neurotech Announces the Opening of Its GMP Manufacturing Facility in Cumberland, Rhode Island

...blished neurotrophic factor, rescues dying retinal photoreceptors and protects them from degeneration. "We are ext...ited disease that causes the retina's rod and cone photoreceptors to gradually degenerate leading to loss of vision ...ter stages dry AMD can lead to the degeneration of photoreceptors and retinal pigment epithelial cells, a chronic co...
Photoreceptors in Biological Dictionary

Cone cells

...s a specialized type of neuron (nerve cell) found in the eye's retina that is capable of phototransduction. The great biological importance of photoreceptors is that as cells they... Cytokines & Cells Online Pathfinder Encyclopaedia ... Cone cells project from the outer retinal surface into a...
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