Pathogens use previously undescribed mechanism to sabotage host immune system
...g OspF from Shigella and SpvC from Salmonella, are phosphothreonine
lyases that promote pathogenicity by directly targ...gnizing the phosphotyrosine and then maneuvers the phosphothreonine
into the enzyme active site. These data implicated...osphorylated MAPK substrates by the OspF family of phosphothreonine
lyases and explain the enzymes differential activi...