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Phosphoprotein in Medical News

Cell Biosciences Announces First UK System Sale

...leukaemic stem cells. The Cell Biosciences system will be used to study how phosphoprotein signaling processes in hematopoietic stem cells are affected during leukaem...omics. We develop instrumentation systems and assays for the measurement of phosphoprotein signaling and activation in extremely small biological samples. Our company...

Scripps Florida scientists develop a process to disrupt hepatitis C virion production

...sen, an assistant professor in the Department of Infectology at Scripps Florida, and his colleagues describe how they used mutations of the viral NS5A phosphoprotein to disrupt virus particle production at an early stage of assembly. NS5A has long been proposed as a regulator of events in the HCV life cycle, but ex...
Phosphoprotein in Medical Technology

Intra-Cellular Therapies Announces Successful Outcome of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

...e Company's first-in-class dual 5HT2A receptor antagonist/dopamine receptor phosphoprotein modulator (DPPM) for the treatment of schizophrenia. A low dose formulation...e Company's first-in-class dual 5HT2A receptor antagonist/dopamine receptor phosphoprotein modulator (DPPM) for the treatment of schizophrenia. ITI-007 has dual prope...

Intra-Cellular Therapies Announces the Discovery of Potent Antidepressant Activity in ITI-007

...onal preclinical data from its ongoing development programs for ITI-007, the Company's first-in-class dual 5HT2A receptor antagonist/dopamine receptor phosphoprotein modulator (DPPM), and ITI-722, a low-dose formulation of ITI-007, which are in development for schizophrenia and sleep disorders, respectively. These ...

Intra-Cellular Therapies Announces the Discovery of Potent Antidepressant Activity in ITI-007/ITI-722

...onal preclinical data from its ongoing development programs for ITI-007, the Company's first-in-class dual 5HT2A receptor antagonist/dopamine receptor phosphoprotein modulator (DPPM), and ITI-722, a low-dose formulation of ITI-007, which are in development for schizophrenia and sleep disorders, respectively. These ...

Intra-Cellular Therapies Presents Preclinical Data From Schizophrenia and Sleep Maintenance Programs

...re/ -- Intra-Cellular Therapies, Inc. (ITI) presented preclinical data on ITI-007, its first in class dual 5HT2A receptor antagonist/dopamine receptor phosphoprotein modulator (DPPM) at a major medical meeting last week. The Company is developing ITI-007 for the treatment of schizophrenia and other related psychiat...
Phosphoprotein in Biological Technology

Feasibility of Multiplexing Bio-Plex Total Target and Phosphoprotein Assays

Qian Gao, Joella Blas, and Efthalia Gerasimopoulos, Bio-Rad Laboratories, Inc., Hercules, CA 94547 USA Introduction Bio-Plex assays allow detection of mutiple target proteins in a small volume of sample. The assays are based on detect...

Cell Biosciences Closes $10 Million Series C Financing

... immunoassay system designed to analyze proteins in extremely small biological samples. Researchers use our products to discover subtle details about phosphoprotein signaling in a wide variety of biological systems. Cell Biosciences has sold systems and established direct distribution organizations in North Ameri...

Intra-Cellular Therapies Reports Positive Final Results of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

...at can act simultaneously as a 5HT2A receptor antagonist, dopamine receptor phosphoprotein modulator (DPPM), and inhibitor of serotonin reuptake. These additional act...e Company's first-in-class dual 5HT2A receptor antagonist/dopamine receptor phosphoprotein modulator (DPPM) for the treatment of schizophrenia. ITI-007 has dual prope...

Cell Biosciences Introduces Kits for Oncoprotein Analysis

...nt of Research and Development. "They enable robust analysis of MEK and ERK phosphoprotein signaling, and provide a unique window into the specific actions of kinase ...omics. We develop instrumentation systems and assays for the measurement of phosphoprotein signaling and activation in extremely small biological samples. Our company...

Cell Biosciences Delivers Next Generation System to Stanford University

... Cell Biosciences is a private life sciences company focused on nanoproteomics. We develop instrumentation systems and assays for the measurement of phosphoprotein signaling and activation in extremely small biological samples. Our company's lead product is a capillary-based nanofluidic immunoassay platform that...

deCODE genetics Announces First Quarter 2008 Financial Results

...as been shown to dramatically inhibit platelet aggregation as well as platelet activation mediated specifically through vasodilator-stimulated phosphoprotein (VASP), a biomarker useful for measuring platelet activity. These effects have been shown to be concentration-dependent and irrespective of wh...

deCODE Genetics Announces Full-year 2007 Financial Results

...041 was shown to dramatically inhibit platelet aggregation as well as platelet activation mediated specifically through vasodilator stimulated phosphoprotein (VASP), a biomarker useful for measuring platelet activity. These effects were concentration-dependent and were seen irrespective of whether p...

deCODE genetics Announces Third Quarter 2007 Financial Results

...demonstrated that in a concentration-dependent manner DG041 dramatically inhibits platelet activation mediated through vasodilator- stimulated phosphoprotein (VASP) as well as platelet aggregation. Moreover, the desired effect on VASP -- a biomarker useful for gauging platelet activation -- appears ...

Application of the Bio-Plex Cell Lysis Kit in Western Blot Analysis of Phosphoproteins, Rev A

...s by transitioning to Bio-Rads Bio-Plex phosphoprotein assays, which employ Luminex xMAP techn... or tissue sample lysates for analysis by Bio-Plex phosphoprotein assays. We recently evaluated the Bio-P...ins The western blot signals for each phosphoprotein were quantitated (AfCS protocol PP00000...

Detection of Phosphorylated and Total ERK and p38 MAPK by Bio-Plex Assay, ELISA, and Western Blotting, Rev A

...eins. These techniques include Bio-Plex phosphoprotein assays, which are multiplex bead-based ... study, commercially available Bio-Plex phosphoprotein and total target assays, and phosphoprotein and total ELISA assays, are compared wi...
Phosphoprotein in Biological Products

Rabbit Anti-NPM1 Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.

Description:... nucleophosmin (nucleolar phosphoprotein B23, numatrin), mRNA...
Company:Proteintech Group, Inc.

Rabbit Anti-SKAP55 Polyclonal Antibody, Unconjugated from ABR-Affinity BioReagents

Description:...immunoprecipitation and immunocytochemical procedures. PA1-525 antigen corresponds to amino acids 2-105 of human SKAP-55.Src kinase-associated phosphoprotein of 55 kDa (SKAP55) is expressed as a constitutively tyrosine phosphorylated 55-kD adapter protein that positively regulates TCR signaling. SKAP55 has...
Company:ABR-Affinity BioReagents
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(Date:9/16/2014)... chunk of rock hit the Yukatan peninsula near the site ... 100 teratons of TNT. It left a crater more than ... and volcanism are widely accepted to have wiped out the ... But what happened to the plants on which the dinosaurs ... University of Arizona reveals that the meteorite impact that spelled ...
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