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Phosphate in Medical News

Sagent Pharmaceuticals Announces Launch of First Two Oncolytic Products: Fludarabine Phosphate for Injection, USP and Epirubicin Hydrochloride Injection

SCHAUMBURG, Ill., Aug. 5 /PRNewswire/ -- Sagent Pharmaceuticals, Inc., a privately-held specialty pharmaceutical company, today announced that it has launched fludarabine phosphate for injection, USP and epirubicin hydrochloride injection. IMS data indicates the combined U.S. market...

PharmaForce Inc. Receives FDA Approval for First Generic of Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension, USP

COLUMBUS, Ohio, July 31 /PRNewswire/ -- PharmaForce, Inc., announced today that it has received approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension, USP, a ...

High-normal phosphate levels linked to early atherosclerosis

Healthy adults with higher levels of phosphate in the blood are more likely to have increased levels of calcium in the coronary arteriesa key indicator of atherosclerosis and future cardiovascular disease risk, reports a study in the February 2009 issue of the Journal of the American Society of N...

Bowel prep oral sodium phosphate equal to fasting before capsule endoscopy for obscure GI bleeding

OAK BROOK, Ill. JUNE 18, 2008 According to a new study from researchers in France, bowel preparation with oral sodium phosphate for capsule endoscopy in patients with obscure gastrointestinal (GI) bleeding is no better at cleansing the small bowel than the standard method of preparation, which ...

How does sodium phosphate combined with bisacodyl affect small intestine?

Capsule endoscopy is a well accepted tool for evaluation of small bowel pathologies (e.g., bleeding sources). However, it has some limitations due to restricted recording time and reduced visibility by air and residual material. Several forms of preparation (e.g., prokinetic drugs, laxatives and ...

Cutting Phosphate May Protect Kidney Patients From Heart Trouble

High levels are major source of cardiovascular death risk in those with chronic disease WEDNESDAY, April 23 (HealthDay News) -- Readily available phosphate-binding drugs could help prevent heart disease in people with chronic kidney disease (CKD), a new study finds. Researchers at ...
Phosphate in Medical Technology

BioCryst Pharmaceuticals Reports Positive Results of Shionogi & Co. Sponsored Phase 3 Studies of i.v. Peramivir for Influenza

...dy of i.v. peramivir that compared the efficacy and safety of a single dose of peramivir (either 300 mg or 600 mg) and treatment with oral oseltamivir phosphate 75 mg (Tamiflu((R))) twice a day for five days. A total of 1,099 patients were enrolled at 146 centers (Japan:100; Korea:25; Taiwan:21). Both the 300...

Keryx Biopharmaceuticals, Inc. Commences Phase 1 Study of KRX-0401 (Perifosine) in Recurrent Pediatric Solid Tumors at Memorial Sloan-Kettering Cancer Center

...ric citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. The Company is also devel...

Keryx Biopharmaceuticals Announces Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

...ric citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. The Company is also devel...

Keryx Biopharmaceuticals Reports Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

...ric citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. The Company is also deve...

Keryx Biopharmaceuticals Reports Single Agent Phase 2 Data of KRX-0401 (Perifosine) Further Demonstrating KRX-0401's Activity in the Treatment of Advanced Metastatic Renal Cell Cancer

...ric citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. The Company is also devel...

Kensey Nash Announces Presentations on its Cartilage Repair Device at the International Cartilage Repair Society Meeting

...oncluded. The CRD is a composite of several resorbable biomaterials, utilizing the Company's proprietary collagen technology, and beta-tricalcium phosphate mineral suspended in a synthetic polymer Porous Tissue Matrix (PTM). This device architecture is designed to repair damaged articular cartilage. The C...
Phosphate in Medical Products

SICKLEDEX

Description:... reconstituted solubility buffer and 20l of anticoagulated whole blood or 20l of sickle cell hemoglobin control. Each test kit contains two bottles of phosphate buffer with Saponin, two buffer dispensing caps and two vials of Sodium Hydrosulfite reagent powder. Reconstituted solution has an open-vial stability...
Company:Streck

Zyderm® and Zyplast® Injectable Collagen Implants

Description:...derm® or Zyplast® collagen implants. Zyderm and Zyplast implants are composed of highly purified bovine dermal collagen that is dispersed in phosphate buffered physiological saline containing 0.3% lidocaine....
Company:INAMED Aesthetics

Immersion Oil, BTL

Description:... Immersion oil composed on polyester polyol, diphenyl cresyl phosphate and tricyclodecane dimethanol....
Company:Carl Zeiss MicroImaging, Inc.

MM-PTH RIA Test

Description:...fold higher than Intact or N-terminal PTH concentrations. PTH acts directly on bone and kidney and indirectly on the intestine to alter calcium and phosphate concentrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and nonparath...
Company:Diagnostic Systems Laboratories, Inc.

C-PTH RIA Test

Description:...fold higher than Intact or N-terminal PTH concentrations. PTH acts directly on bone and kidney and indirectly on the intestine to alter calcium and phosphate concentrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and nonparath...
Company:Diagnostic Systems Laboratories, Inc.

I-PTH IRMA Test

Description:...fold higher than Intact or N-terminal PTH concentrations. PTH acts directly on bone and kidney and indirectly on the intestine to alter calcium and phosphate concentrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and nonparath...
Company:Diagnostic Systems Laboratories, Inc.
Phosphate in Medical Dictionary

Calcium phosphate

Calcium phosphate is the name given to a family of minerals containing calcium ions (Ca2+) together with orthophosphates (PO43-), metaphosphates or pyrophosphates (P2O74-) and occasionally hydrogen or hydroxide ions. Monocalcium phosphate is a chemical compound with the formula Ca(H2PO4...

Vitamin B6

... Vitamin B6 is a water-soluble vitamin and is part of the vitamin B complex group. Pyridoxal phosphate (PLP) is the active form and is a cofactor in many reactions of amino acid metabolism, including transamination,... ... Dietary Allowance for v...

Tissue

... Tissue from the human ascending aorta was harvested from pediatric patients ... After harvesting, the arterial tissue was rinsed of blood with phosphate ... Find a reliable & professional Tissue Paper manufacturer or supplier. ... Paper Napkins & Serviettes (691) Tissue Boxes (483) Spec...

Thiamine

... Thiamine , or thiamin, sometimes called aneurin, is a water-soluble vitamin of the B complex (vitamin B1), whose phosphate derivatives are involved in many cellular processes. The best characterized form is thiamine ... thiamine ( ) also thiamin n. A vitamin, C 12 H...

Sucrose

...pages to find the most relevant information on sucrose , and allows you to compare prices on... Learn about the prescription medication Codeine phosphate (Codeine Phosphate), drug uses, dosage, side ... These tablets also contain lactose and sucrose . ... ... separately conditioned to associate...

Serum phosphorus

...e serum phosphorus test measures the amount of phosphate in the blood. ... The serum phosphorus test measures the amount of phosphate in the blood. Alternative Names ... Phosphorus -...e serum phosphorus test measures the amount of phosphate in the blood. ... Serum phosphorus - Overv...
Phosphate in Biological News

New study reveals the protein that makes phosphate chains in yeast

It can be found in all life forms, and serves a multitude of purposes, from energy storage to stress response to bone calcification. This molecular jack-of-all trades is polyphosphate, a long chain of phosphate molecules. Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelber...

Discovery that bacterium is phosphate gourmet key clue to what makes it most social of bacteria

New research into one of the world's most social bacteria - Myxococcus xanthus, has discovered that it has a gourmet style approach to its consumption of phosphates, which provides a key clue to what makes it the most "social" of bacteria. Myxococcus xanthus is amazingly social and co-operative f...

NIH stimulus funding supports Emory biomedical scientists

...les for manipulating the immune system. Dietary phosphate and prostate cancer: The nutrient phosphate is an additive in products ranging from soft drink...on. This project monitors the influence of dietary phosphate on a mouse model of prostate cancer. Understand...

Grant supports LSUHSC research on how like cell receptor systems determine very different functions

... and Reinvestment Act and will be used to help retain key personnel needed to identify and characterize ERK phosphorylation targets proteins to which phosphate groups can be added, increasing or decreasing protein function specified by the scaffold. These phosphorylation targets are involved in the developme...

Baylor researchers unravel mystery of DNA conformation

...reate, the late Dr. Linus Pauling, who asked how the information encoded by the bases could be read if it is sequestered inside the DNA molecular with phosphate molecules on the outside. It's easy to explain when the cell divides because the double-stranded DNA also divides at the behest of a special enzyme...

Protein can help cells or cause cancer, Purdue researcher finds

...tic approach to treating that cancer." During cell growth, Plk1 uses its protein kinase activity called phosphorylation, which consists of adding a phosphate group to a protein called Topors. Topors binds itself to p53 molecules during the ubiquitination process. Phosphorylation is basically an instruction ...
Phosphate in Biological Technology

Awareness of Genzyme's Renvela(R) (Sevelamer Carbonate) is High, Although Uptake of this New Phosphate Binding Agent has Been Slower than Nephrologists and Renal Dietitians Initially Expected

EXTON, Pa., May 23 /PRNewswire/ -- BioTrends Research Group, Inc. released Wave 1 of its LaunchTrends(TM): Renvela report, the second in a multi-phase syndicated market research project tracking the launch of Renvela from baseline awareness through the first six months of product availability....

Genzyme to Participate in FDA Advisory Committee Meeting on the Use of Phosphate Binders in Chronic Kidney Disease

CAMBRIDGE, Mass., Oct. 12 /PRNewswire-FirstCall/ -- Genzyme Corporation (Nasdaq: GENZ ) announced that the U.S. Food and Drug Administration's Cardiovascular and Renal Products Advisory Committee will meet Tuesday to consider the use of phosphate binders in patients with chronic kidney diseas...

Keryx Biopharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results

...ric citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. Keryx is also developing ...

Shire plc: Core Portfolio of Products Delivers 20% Sales Growth

...sed as the product entered new countries, and continued to grow in countries entered in the last two years. In the US, FOSRENOL's average share of the phosphate binder market in Q2 2009 declined to 7.8% (2008: 8.2%) due to a 3% decrease in prescriptions. However, US product sales grew 15% as price increases of...

Keryx Biopharmaceuticals, Inc. to Hold Conference Call on Second Quarter 2009 Financial Results on Thursday, August 6, 2009 at 8:30am EDT

...ric citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. Keryx is also developing ...

Keryx Biopharmaceuticals Reports Positive Phase 2 Study Results of Zerenex (Ferric Citrate) for the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients

...ence to that reported for other currently marketed phosphate binders. There was no increase in serum calcium n...s, suggest that Zerenex is an effective, tolerated phosphate binder that will potentially make a significant cl...s significant market potential for the drug in the phosphate binder space." Mr. Bentsur continued, "We're excit...
Phosphate in Biological Products

Rabbit Anti-Human Lipid Phosphate Phosphohydrolase 2 Polyclonal Antibody, Unconjugated from Exalpha Biologicals, Inc.

Description: Lipid Phosphate Phosphohydrolase 2...
Company:Exalpha Biologicals, Inc.

Calcium Phosphate Transfection Kit from Invitrogen

Description: Invitrogen's Calcium Phosphate Transfection Kit provides high-quality reagents to enable the introduction of DNA into tissue culture cells via calcium phosphate co-precipitation....
Company:Invitrogen

Rabbit Anti-Lipid Phosphate Phosphatase 2 (LPP2) Antibody, Unconjugated from Sigma-Aldrich

Description: Anti-Lipid Phosphate Phosphatase 2 (LPP2) fractionated antiserum buffered aqueous solution Solution in phosphate buffered saline containing 0.08% sodium azide. unique peptide derived from the human LPP2 protein. The amount of the reagent is sufficient for 10 blots....
Company:Sigma-Aldrich

Dulbecco's Phosphate Buffered Saline (DPBS) from Sigma-Aldrich

Description: ...
Company:Sigma-Aldrich

Dulbecco's Phosphate Buffered Saline (DPBS) from Sigma-Aldrich

Description: With 36 mg/L sodium pyruvate, 50 mg/L streptomycin sulfate, 100 mg/L kanamycin monosulfate, 1000 mg/L glucose, calcium chloride, and magnesium chloride. The use of a balanced salt solution (BSS) in tissue culture is generally attributed to early workers in the field. In 1885, Sydney Ringer develope...
Company:Sigma-Aldrich

Coating Stabilizer from ScyTek Laboratories

Description:...of the dried immunoassay components. Product is filtered at 0.2 microns. Contents: Aqueous, protein-containing stabilizer and blocking solution in phosphate buffer for dried protein components in immunoassays. Preservative: 0.02% Bromonitrodioxane, 0.02% 2-Methyl-4-isothiazolin-3-one. pH 7.2 - 7.7...
Company:ScyTek Laboratories

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Phosphate in Biological Definition

Adenosine triphosphate

...Chemically, ATP consists of adenosine and three phosphate groups. It has the empirical formula C 10 H 16 N ... cell. Also, the hydrolysis yields free inorganic phosphate and adenosine diphosphate , which can be broken down further to another phosphate ion and adenosine monophosphate . ATP can also be...

ATP synthase

...( EC 3.6.3.14) is a general term for an enzyme that can synthesize adenosine triphosphate (ATP) from adenosine diphosphate (ADP) and inorganic phosphate by utilizing some form of energy. The overall reaction sequence is: ADP + P i → ATP ATP synthase in E. coli These enz...

ATPase

...denosine triphosphate (ATP) into adenosine diphosphate (ADP) and a free phosphate ion . This dephosphorylation reaction releases energy , which the enz...ransmembrane proton gradient as an energy source for adding an inorganic phosphate group to a molecule of adenosine diphosphate (ADP) to form a molecule of...

Bone

...ht composite material , formed mostly of calcium phosphate (in the chemical arrangement termed calcium hydrox...les containing alkaline phosphatase. This cleaves phosphate groups and acts as the foci for calcium and phosphate deposition. The vesicles then rupture and act as a...

Biopolymer

...5' end to the 3' end of the polymer chain , where 5' and 3' refer to the numbering of carbons around the ribose ring which participate in forming the phosphate diester linkages of the chain. Such a sequence is called the primary structure of the biopolymer. There are a number of biophysical techniques f...

Carbohydrate

...tric acid cycle oxidative phosphorylation See also Biochemistry Macromolecules Glycolysis Gluconeogenesis Pentose phosphate pathway External links IUPAC-IUBMB Joint Commission on Biochemical Nomenclature (JCBN): Carbohydrate Nomenclature Carbohydrates detail...
Phosphate in Biological Dictionary

Transient transfection

...al students and researchers ... 4. Transient transfection using calcium phosphate ... Transient Transfection of Procyclic form T. brucei. Notes: 1. .....he protocol for transient transfection of adherent cells with calcium phosphate ... Transient . transfection often results in high ... Transient t...

Ribonucleotides

... ribonucleotide in living beings. Ribonucleotides have one, two, or three phosphate groups attached to the... Disodium 5'- ribonucleotides , E number E6...tains ribose as its sugar and ... Ribonucleotides have one, two, or three phosphate groups attached to the ribose sugar. ... RNA ( ) n. A polymeric constitu...

Primary root

...seedling ... contains the primary root or radicle, ... The Effect of phosphate Availability on Cell Length at the Primary Root Tip ... The effect of phosphate availability on cell length at the primary root tip. ... 1. Unders...

Pre-mRNA

...nd a closed complex in which pre - mRNA is sequestered at an early stage of spliceosome assembly. ... ... the structure is a good mimic of the phosphate group of the pre - mRNA substrate. ... Polyadenylation factor CPSF-73 is the pre - mRNA 3'-end-processing endonuclease. ... Pre mRNA infor...

Polynucleotide Kinase

...buffer. Alkaline Phosphatase, shrimp; ... T4 Polynucleotide Kinase is also a 3'-phosphatase. ... · T4 polynucleotide kinase is inhibited by phosphate and ammonium ions. ... T4 Polynucleotide Kinase . BioChain. 500 units. Inquire. Inquire ... Biomolecule Products : Polynucleotide Kinase (cl...

Phosphorylation

... Phosphorylation is the addition of a phosphate (PO4) group to a protein or other organic molecule. Phosphorylation turns many protein enzymes on and off, causing or preventing the mechanism...
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