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Phenytoin in Medical News

Two Studies at AACE 2009 Annual Meeting Highlight Effects of Welchol(R) (colesevelam HCl) on Blood Glucose and LDL-C in Patients with Type 2 Diabetes

... establish a causal relationship. Increased seizure activity or decreased phenytoin levels have been reported in patients receiving phenytoin concomitantly with Welchol. Reduced International Normalized Ratio (INR) ...

Guidelines: Pregnancy Safe with Epilepsy, but Valproate Should be Avoided

...nd the pregnant woman seizure free." The guidelines also state that physicians of women with epilepsy should consider avoiding the epilepsy drugs phenytoin and phenobarbital in order to prevent the possibility of decreased thinking skills in children. In addition, the guidelines recommend women with epile...

Pregnant Women With Epilepsy Should Avoid Valproate

...the time to experiment with different medications is before you get pregnant. While it's best to avoid certain drugs, such as valproate and also phenytoin and phenobarbital, according to the guidelines, it's not always possible to do so. Some women must use these medications to control their seizures. ...

Epilepsy Drug Impairs Baby's Intelligence

...ly lower IQ scores than the children exposed to the other medications. The average IQ for children exposed in the womb to lamotrigine was 101, for phenytoin it was 99, and for carbamazepine it was 98. Children exposed to valproate in the womb scored an average of 92 on the IQ test, according to the study. ...

New research suggests common anti-seizure medications may increase risk of cardiovascular problems

...ti-seizure medications that will not adversely affect cardiovascular health. The study involved two of the most widely-prescribed anticonvulsants phenytoin (Dilantin) and carbamazepine (Tegretol, Carbatrol) which have potent effects on many enzymes in the body involved in different areas of metabolism. ...

Treadmill Desks: A Healthy Alternative on the Heels of FDA Warnings of 25 Weight Loss Products

...fits as well: treadmill desks . Potentially harmful ingredients contained in these products marketed as "herbal and/or natural" include phenytoin (which is an antiseizure drug), sibutramine (a controlled substance), rimonabant (not approved in the US), and phenolphthalein (suspected carcinogen)....

FDA Warns About Weight Loss Products

...gredients in some of these products include sibutramine (a controlled substance), rimonabant (a drug not approved for marketing in the United States), phenytoin (an anti-seizure medication), and phenolphthalein (a solution used in chemical experiments and a suspected cancer-causing agent). Some of the amounts ...

FDA Adds Suicide Warning to Epilepsy Drugs

...rugs, which includes widely used medications such as clonazepam (Klonopin), phenytoin (Dilantin) and topiramate (Topamax). "Patients being treated with antiep...s and refer them to psychiatrists," he added. In addition to clonazepam, phenytoin and topiramate, the drugs covered by the new FDA-mandated labeling are: car...

Data from Pooled Analyses Demonstrates Welchol, Combined with Metformin- or Sulfonylurea-Based Therapy, Significantly Lowers Blood Glucose in Adults with Type 2 Diabetes

...or establish a causal relationship. Increased seizure activity or decreased phenytoin levels have been reported in patients receiving phenytoin concomitantly with Welchol. Reduced International Normalized Ratio (INR) ha...

Breast-Feeding While on Seizure Meds Doesn't Harm Babies

... meeting, in Chicago. The cognitive development of 187 2-year-old children whose mothers were taking the epilepsy drugs lamotrigine, carbamazepine, phenytoin or valproate were tested in the study. Of these children, 41 percent were breast-fed. The children of mothers who breast-fed while on the epilepsy ...
Phenytoin in Medical Technology

New Discovery of Key Difference in Bile Acid Metabolism in Patients with Type 2 Diabetes May Suggest Underlying Disorder

...or establish a causal relationship. Increased seizure activity or decreased phenytoin levels have been reported in patients receiving phenytoin concomitantly with Welchol. Reduced International Normalized Ratio (INR) ha...

Welchol(TM) Lowered A1C by a Mean 1 Percent or Greater When Added to Metformin-, Insulin-, or Sulfonylurea-Based Therapy in 47 Percent of Patients Evaluated

...or establish a causal relationship. Increased seizure activity or decreased phenytoin levels have been reported in patients receiving phenytoin concomitantly with Welchol. Reduced International Normalized Ratio (INR) ha...

Photo: Welchol(TM) (colesevelam HCl) Receives FDA Approval to Reduce Blood Glucose in Adults with Type 2 Diabetes

...or establish a causal relationship. Increased seizure activity or decreased phenytoin levels have been reported in patients receiving phenytoin concomitantly with Welchol. Reduced International Normalized Ratio (INR) ha...

Halozyme Therapeutics Announces Peer-Reviewed Publications of the INFUSE-LR Clinical Trial Results and Clinical Practice Experience With Hylenex

...or stings. Hyaluronidase should not be used for intravenous injections because the enzyme is rapidly inactivated. Furosemide, the benzodiazepines, and phenytoin are incompatible with hyaluronidase. For more information about HYLENEX please visit http://www.HYLENEX.com or call 1-800-262-3784. HYLENEX is a tra...
Phenytoin in Medical Products

CEDIA® Phenytoin II

Description: Our high quality therapeutic drug monitoring reagents, calibrators and controls are available for most chemistry analyzers. Reproducible and accurate results for your laboratory needs....
Company:Microgenics Corporation

Emit® Phenytoin Assay

Description: The Emit Phenytoin Assay is a homogeneous enzyme immunoassay for use in the quantitative analysis of phenytoin in human serum or plasma....
Company:Dade Behring, Inc.

Emit®2000 Phenytoin Assay

Description: The Emit 2000 Phenytoin Assay is a homogeneous enzyme immunoassay intended for use in the quantitative analysis of phenytoin in human serum or plasma. Emit 2000 assays are designed for use with most chemistry analyzers....
Company:Dade Behring, Inc.

Emit® 2000 (Convenience Pack) Phenytoin Assay

Description: The Emit 2000 Phenytoin Assay is a homogeneous enzyme immunoassay intended for use in the quantitative analysis of phenytoin in human serum or plasma. Kits are packaged specifically for use on the Roche COBAS MIRA, COBAS MIRA S, and COBAS MIRA Plus chemistry systems...
Company:Dade Behring, Inc.

OSR Phenytoin Assay

Description: The Emit 2000 Phenytoin Assay is a homogeneous enzyme immunoassay for use in the quantitative analysis of phenytoin in human serum or plasma. Kits are conveniently packaged in Olympus Reagent Cartridges for use on the AUTM Series Chemistry Systems....
Company:Dade Behring, Inc.

Free Phenytoin

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

IMMULITE Phenytoin

Description: IMMULITE and IMMULITE 1000 assays are designed for use with the IMMULITE and IMMULITE 1000, continuous random access immunoassay analyzers which offer simplicity in both design and operation. IMMULITE systems can be found in a wide variety of immunoassay testing environments around the world....
Company:Siemens Medical Solutions Diagnostics

Phenytoin

Description:... For the quantitative in vitro determination of phenytoin in human serum....
Company:Randox Laboratories Ltd.

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Phenytoin in Medical Dictionary

Phenytoin overdose

... Historically, phenytoin has been used as an antidysrhythmic agent, ... phenytoin toxicity depends on the route of administration, duration, exposure, and dosage. ... phenytoin overdose . Contents of this page: Alternative Na...
Phenytoin in Biological News

UNC launches study of liver injury caused by drugs

...since 1994 developed severe liver injury due to one of four specific drugs. The four are the tuberculosis drug isoniazid, the anti-seizure medications phenytoin and valproic acid, and the antibiotic amoxicillin-clavulanate potassium. "Eligible patients from anywhere in North Carolina or neighboring states w...

Gene variations explain drug dose required to control seizures

...proximately 181,000 new cases diagnosed each year. phenytoin and carbamazepine are important first-line anti-ep...isions," he continued. Control of epilepsy with phenytoin can be a difficult and lengthy process because of ...a significant association with the maximum dose of phenytoin taken by patients with epilepsy. Moreover, a va...
Phenytoin in Biological Technology

Beyond Seizure Control in the Treatment of Epilepsy With New Anti-Epileptic Drug, Zebinix(TM)

... (12). WHO Atlas: Epilepsy Care in the World. WHO 2005 (13). Mattson, RH, Cramer, JA, et al. Comparison of carbamazepine, phenobarbital, phenytoin and primidone in partial and secondarily generalized tonic clonic seizures. New England Journal of Medicine 313:145-151, 1985. (14). Mattson, ...

Baxter and Halozyme Announce Collaboration for Development of Subcutaneous GAMMAGARD LIQUID(TM) Administration Using Enhanze(TM) Technology

...he cornea. Hyaluronidase should not be used for intravenous injections because the enzyme is rapidly inactivated. Furosemide, the benzodiazepines and phenytoin have been found to be incompatible with hyaluronidase. The most frequently reported adverse experiences have been local injection site reactions. Hyal...

Immunoassay of Theophylline by fluorescence polarisation

...nt drugs: gentamicin at 5 g/mL theophylline at 17.8 g/mL tobramycin at 6.5 g/mL quinidine at 2.6 g/mL phenytoin at 12 g/mL digoxin at 2.2 ng/mL salicylate at 220 g/mL acetaminophen at 217 g/mL lithium at 1.2 meq/L ...
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