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Pharmacogenomic in Medical News

GeneGo Awarded NIH Grant to Develop Pharmacogenomics Software Suite

...Inc., the leading systems biology company, today announced that it has been awarded a grant to develop an integrated systems pharmacology platform for pharmacogenomic research. The SBIR grant, funded through the innovations in biomedical computational science and technology initiative, will be used to develop a data...

Cascade of Studies, New Clinical Tests Build the Case for Genetic Testing in Pharmacy Care Says Medco Expert

...ospital admissions and less waste, Frueh said. He predicts that the use of pharmacogenomic testing will become increasingly popular over the next several years as cli...r Atlantic Information Services, Inc., Frueh - who prior to leading Medco's pharmacogenomic research efforts led a core genomics review team at the U.S. Food and Drug ...

UC San Diego to lead nationwide program in pharmacogenomics

... knowledge and the expectations of patients regarding pharmacogenomics testing. A major aim of the program is to increase awareness of the use of pharmacogenomic testing and its potential implications. "Typing major genes affecting drug action has become cost effective and various genetic tests have been develo...

InHealth awards grants to study impact of medical diagnostics and devices on patients, health care

...y of Houston, will examine patient preferences when it comes to personalized medicine and the trade-offs that patients make in deciding whether to use pharmacogenomic testing, which identifies patients who are likely to have the most (or least) toxicity from a drug. The findings are expected to contribute to underst...

Singulex Advances Conversation on Personalized Medicine

... HALF MOON BAY, Calif., May 13 /PRNewswire/ -- Personalized medicine is changing the face of healthcare. Currently, pharmacogenomic tests can help physicians determine the right dosing schedule for warfarin or to predict the potential for adverse drug reactions. In the near future,...

Medco Breaks Ground For World's Largest Automated Pharmacy

...ating with Mayo Clinic on a comprehensive community-based study of more than 1,000 patients taking warfarin. The study involves research on the use of pharmacogenomic testing for the proper dosing of warfarin, a blood thinner that is notoriously difficult to administer, and is evaluating savings from the safer use o...

Scientific poster abstracts from the 24th annual meeting of the American Academy of Pain Medicine

...Pain Associated with Muscle Spasms: A Pooled Analysis of Two Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multicenter Studies 207 pharmacogenomic Evaluation of Methadone Toxicity in a Therapeutic Pain Management Patient: A Case Report 209 Efficacy of a Single, Percutaneous, Across Midline, O...

Anticancer Drugs Targeting the ErbB (EGFr/HEr2) Pathway Alone Generated Global Sales of Nearly $5 Billion in the First Nine Months of 2007

...rgeted agents in development are ushering in the age of personalized medicine. There is pressing need for better diagnostic, theragnostic, prognostic, pharmacogenomic and disease monitoring methodologies for patient selection and optimized treatment. The source, mechanisms of action, and preclinical and clinical s...

Response Genetics Reports Third Quarter 2007 Financial Results

...rs as clinical results become available. About Response Genetics, Inc. Response Genetics, Inc. ("RGI") is engaged in the research and development of pharmacogenomic cancer diagnostic tests based on its proprietary and patented technologies. RGI's technologies enable extraction and analysis of genetic information f...

Response Genetics to Announce Third Quarter 2007 Financial Results on Wednesday, November 14, 2007

...release on Wednesday, November 14, 2007. About Response Genetics, Inc. Response Genetics, Inc. ("RGI") is engaged in the research and development of pharmacogenomic cancer diagnostic tests based on its proprietary and patented technologies. RGI's technologies enable extraction and analysis of genetic information f...
Pharmacogenomic in Medical Technology

Sirius Genomics Announces New Collaboration with Assistance Publique-Hopitaux de Paris

... 13 /PRNewswire/ - Sirius Genomics, a developer of pharmacogenomic diagnostics, announced today that it has signed a ...nt focuses on the continued development of Sirius' pharmacogenomic diagnostic intended to assess responsiveness to re... Genomics is a drug-enabling company that develops pharmacogenomic (PGx) diagnostics that lead to better patient outc...

EntreMed Presents MKC-1 and ENMD-1198 Preclinical Data at AACR Annual Meeting

...ulation of oncogenic proteins by ENMD-1198. In summary, data demonstrate that ENMD-1198 resistant 1A9 cells may provide a useful tool for evaluating a pharmacogenomic profile that can be correlated with clinical benefit. Dr. Bray commented on the presentations, "We continue to see encouraging potent preclinical an...

New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit

...he Translational Genomics Research Institute's Pharmaceutical Genomics Division located in Scottsdale, Arizona. "This study is an example of using a pharmacogenomic screening approach to find insights that guide the selection of specific contexts of vulnerability for brostallicin. These results provide information...

Oncology Drug Development Update - Molecular Profiling Redefines the Nature of Malignancy and Increases the Adoption of Targeted Therapeutics

... Authoritative cancer agencies are taking notice. The National Comprehensive Cancer Network (NCCN) has begun to incorporate diagnostic, prognostic and pharmacogenomic evaluations in their updated treatment guidelines. Targeted Agents in Combination are Entering Clinical Trials The validated association of aggres...

Accera, Inc. Announces Results of Phase II Study in Alzheimer's Disease at American Academy of Neurology Meeting

...rly well to treatment, as reflected in statistically significant improvement in AD Assessment Scale- Cognitive (ADAS-Cog) scores. Subjects underwent pharmacogenomic analysis for a variety of genetic markers and were evaluated through a battery of neuropsychometric tests at Day 0, 45, and 90. Compared to the placeb...

Accera, Inc. Announces Open-Label Data from Phase II Study in Alzheimer's Disease at International Conference on Prevention of Dementia

...rlier clinical and preclinical studies, AC-1202 was shown to be safe and to significantly improve the memory and cognition of subjects of a particular pharmacogenomic profile. The randomized, double-blinded, placebo-controlled Phase IIb trial evaluated 152 subjects that had previously been diagnosed with mild to m...

Response Genetics Announces Publication of a Phase III Clinical Trial Demonstrating That Low Levels of ERCC-1 Help to Predict Likelihood of Response to Cisplatin-Based Therapy in Lung Cancer

...sponse Genetics, Inc. ("RGI") is engaged in the research and development of pharmacogenomic cancer diagnostic tests based on its proprietary and patented technologies....ly generates revenue primarily from the sales of its proprietary analytical pharmacogenomic testing services of clinical trial specimens to the pharmaceutical industry...
Pharmacogenomic in Biological News

Researchers at UH explore patient preferences for personalized medicine

...ntify what types of trade-offs patients are willing to make when opting for pharmacogenomic testing, which uses genomic information to determine whether a drug is like...ficial or negative reactions. For instance, Issa said, patients considering pharmacogenomic testing must weigh out such things as the cost of the procedure and whether...

American College of Medical Genetics responds to new FDA labeling decision for warfarin

...co-chair of the expert group on Pharmacogenetic Testing of CYP2C9 and VKORC1 Alleles for Warfarin Use. This group is completing a report on the use of pharmacogenomic testing for warfarin and is based on a rapid-ACCE (Analytic validity, Clinical validity, Clinical utility and Ethical, legal and social implications) ...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

... understanding how tumors physiologically respond to therapy and a non-invasive technique for monitoring that response," Dr. Diaz said. Cellular pharmacogenomic to discover genetic determinants of Tykerb response: Abstract 5684 A new high-throughput genetic analysis technique can reveal gene markers ?by...

Genomics researchers discover protein deficit that causes drug toxicity

...ver 20 years ago. "From a clinical point of view, the genetic test we developed at Mayo to predict response to thiopurine drugs has been invaluable to pharmacogenomic medicine -- and now this finding is taking us in promising new directions because we believe our findings can be generalized to apply to many instance...

FDA Works To Speed The Advent Of New, More Effective Personalized Medicines

... "Pharmacogenomic Data Submissions," clarifies how pharmacogenomic data will be evaluated. The final guidance describ...information as we move into more advanced areas of pharmacogenomic research. The voluntary data, which will be review... will be able to familiarize themselves with novel pharmacogenomic approaches as they evolve. FDA's new pharmacoge...
Pharmacogenomic in Biological Technology

New Pharmacogenomic Approach: 454 Life Sciences and Perlegen to Collaborate in Drug Response Sequencing Study

BRANFORD, Conn., Oct. 2 /PRNewswire/ -- 454 Life Sciences, a Roche company, and Perlegen Sciences, Inc., today announced a collaboration to conduct large scale genetic re-sequencing in hundreds of DNA samples collected by Perlegen from humans with specific responses to a widely prescribed clas...

Response Genetics Announces $4 Million Private Placement

...-fixed and paraffin-embedded specimens. In addition to diagnostic testing services, RGI generates revenue from the sales of its proprietary analytical pharmacogenomic testing services of clinical trial specimens to the pharmaceutical industry. The Company was founded in 1999 and its principal headquarters are locate...

Evidence for a New Genetic Link to Therapeutic Efficacy for Alzheimer's Disease

...ons in overall managed care expenditures. To further investigate pharmacogenomic responses of AC-1202 in AD, the effects of APOE4 carriage status and a poly... the number of potential responder patients is substantial. "This pharmacogenomic finding provides both insight into the mechanism of ketone-based therapies ...

Sirius Genomics Announces 2009 Board of Directors

... VANCOUVER, June 8 /PRNewswire/ - Sirius Genomics, a developer of pharmacogenomic diagnostics, announced that it has elected its 2009 Board of Directors at i...genomics.com Sirius Genomics is a drug-enabling company that develops pharmacogenomic (PGx) diagnostics that lead to better patient outcomes through personalized...

Transgenomic, Inc. Announces Appointment of New Board Members

...ccess in leading and running diagnostic reference laboratories. With our continued focus on growing Transgenomic's molecular diagnostic laboratory and pharmacogenomic services lab, plus focusing our WAVE system and related mutation detection technology for greater diagnostic and clinical value, their participation o...

Virco Lab, Inc. Enters Into Collaboration with SmartGene, Inc. Enhancing HIV Resistance Test Services for Laboratories and Physicians

...pany applies the latest technologies in molecular biology, medical virology, and bioinformatics to develop advanced diagnostic tools that are based on pharmacogenomic principles of individualized patient care. A pioneer in HIV resistance testing, Virco has one of the world's largest repositories of HIV clinical isol...

Speid & Associates Partners With Genizon BioSciences to Reduce Attrition Rates of New Drug Compounds

...ner', but which may hold promise as new medications." "We believe that we can add significant value to Speid & Associates' clients through pharmacogenomic studies and analyses using our gene discovery platform and expertise. These enable invaluable insights into drug response, and therefore improve clin...

Sirius Genomics to Present at Invest Northwest Conference

... VANCOUVER, Feb. 23 /PRNewswire/ - Sirius Genomics, a developer of a pharmacogenomic test to identify potential responders to recombinant activated Protein C (s... Sirius Genomics is a drug-enabling company that excels at developing pharmacogenomic (PGx) tests that lead to better patient outcomes through personalized medic...

Sirius Genomics Announces New Collaboration with UK Critical Care Genomics Group

.... 9 /PRNewswire/ - Sirius Genomics, a developer of pharmacogenomic tests, announced today that it has signed a collab...nt focuses on the continued development of Sirius' pharmacogenomic diagnostic for responsiveness to recombinant activ... a drug-enabling company that excels at developing pharmacogenomic (PGx) tests that lead to better patient outcomes t...

Transgenomic Awarded SBIR Grant to Support Development of SURVEYOR(R) Endonuclease Adaptor-ligated Libraries (SEAL) for Determining Whole Genome Sequence Variation

...echnology and its potential to meet unmet market needs. This supports our belief that SEAL will have a significant impact on whole genome analysis for pharmacogenomic studies in personalized medicine and bacterial drug resistance research." About SEAL SURVEYOR Endonuclease Adaptor-ligated Libraries (...
Pharmacogenomic in Biological Products

HS 4800 Hybridization Station from Tecan

Description:...ful tool with many applications in both industrial and academic settings. These applications range from gene expression profiling, gene regulation and pharmacogenomic studies up to the identification of new drug targets and toxicology studies. To serve these diverse areas, Tecans HS 4800 Hybridization Station is a...
Company:Tecan
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Breaking Biology News(10 mins):In lab studies, hydroxyethyl starch has direct harmful effects on kidney cells 2
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