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Phagocytosis in Medical News

Developing gene therapy to fight blindness

...de the retina that closely interacts with photoreceptors in the maintenance of visual function. Patients with loss of MERTK function have a defect in phagocytosis a mechanism used to remove pathogens and cell debris. As a result of this defect, debris accumulates between the photoreceptors and retinal pigment ...

St. Jude finds link between cellular defense processes, showing how cancer cells survive

...er using a common set of signals. The processes of phagocytosis and autophagy enclose various cellular structures ...t orchestrate autophagy and uses them to supervise phagocytosis and the formation of the digestive sac called the ...eds. Immune system cells called phagocytes use phagocytosis for the outside job of environmental cleanup, engu...

St. Jude Finds Link Between Cellular Defense Processes, Showing How Cancer Cells Survive

...er using a common set of signals. The processes of phagocytosis and autophagy enclose various cellular structures ...t orchestrate autophagy and uses them to supervise phagocytosis and the formation of the digestive sac called the ...or of the report. "Now that we discovered that phagocytosis uses some of the same biochemical signals as autop...

Adherence of Nanoparticles to RBC- Very Effective Drug Delivery Method

...ch chemicals to the exposed surface for targeting applications. The researchers have learned that particles adhered to red blood cells can escape phagocytosis because red blood cells have a knack for evading macrophages. Nanoparticles arent the first to be piggybacking on red blood cells; the strategy has al...

Montreal Researchers And US Develop Model Of Key Immune-System Component

...he phagosome. They then constructed a detailed map of the interactions among these proteins and were able to identify previously unknown regulators of phagocytosis and potential molecular pathways of immune defense. "Phagocytosis is very similar in many organisms, so we are able to learn about this process by...

Link between Fish and Mammal Immune Systems Revealed by Killer B cells

...ammals, where B cells produce antibodies to fight infection, to the more primitive innate immunity in fish, where they found that B cells take part in phagocytosis (literally: cell eating), the process by which cells of the immune system ingest foreign particles and microbes. The finding, which appears in the ...

Molecule aids fight E. Coli Infections

...Using a cutting-edge technique that allowed them to turn off specific genes, Ezekowitz and his team identified 36 macrophage proteins essential to the phagocytosis process. One, called PGRP-LC, is a cell surface receptor that sits on the outer membrane and receives chemical signals. When the scientists deactivate...
Phagocytosis in Medical Dictionary

Macrophage

... Macrophage recognition of cells undergoing programmed cell death (apoptosis) ... Role for the class A macrophage scavenger receptor in the phagocytosis of ... Information about macrophage in the free online English dictionary and ... histiocyte - a macrophage that is found in connective tis...

Immune response

...f ... 3 Vaccines and the immune response to vaccination. 4 Maintaining good bird health ... The mosquito cellular immune response includes phagocytosis and encapsulation by ... These differences in the immune responses mounted against different pathogens ... ... cancer vaccines, scientists m...
Phagocytosis in Biological News

Immunity stronger at night than during day

... Drosophila melanogaster, reveal that the specific immune response known as phagocytosis oscillates with the body's circadian rhythm, according to Stanford research...roy the bacteria invading the body. In humans, immune responses such as phagocytosis not only are involved in clearing bacterial infection but also are implicat...

Proteomics study yields clues as to how tuberculosis might be thwarting the immune system

...utophagy was suppressed. This indicates cross-talking between autophagy and phagocytosis that may play an important role in the response of the immune system." ..., until now there has been no direct biochemical evidence of a link between phagocytosis and autophagy. Working with latex bead-containing phagosomes isolated in...

Discovery in the evolution of the immune system absorbing cells

...ish as well as in amphibians are capable of strong phagocytosis both in in vivo and in vitro experiments. The work...e of fish and amphibians makes the preservation of phagocytosis an evolutionary advantage to B cells in their defe... design of vaccines for fish in order to stimulate phagocytosis in antibodies for B cells, increasing the effectiv...

Researchers in Montréal and the US create model of key immune-system component

...e phagosome. They then constructed a detailed map of the interactions among these proteins and were able to identify previously unknown regulators of phagocytosis and potential molecular pathways of immune defense. "Phagocytosis is very similar in many organisms, so we are able to learn about this process b...

'Killer' B cells demonstrate evolutionary link between fish and mammal immune systems

...ammals, where B cells produce antibodies to fight infection, to the more primitive innate immunity in fish, where they found that B cells take part in phagocytosis (literally: cell eating), the process by which cells of the immune system ingest foreign particles and microbes. The finding, which appears in the ...

Case Western Reserve University researchers find protein associated with brain cell death

...lular Signaling Cascades Require Vav for Induction of Respiratory Burst and phagocytosis in Monocytes and Microglia." The researchers discuss the role that the ...mulate intercellular signaling cascades as well as initiate a novel type of phagocytosis (cell death) in microglia." "Vav has been found to be the key regulato...

UCSB researchers discover shape matters to macrophages

... Researchers at UC Santa Barbara have made a surprising discovery: phagocytosis depends more on particle shape than size. The research, which has far-reach...was believed that the ability of a macrophage to process a particle through phagocytosis was dependent solely on its size. Previous studies have been performed only...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

...siderably. The researchers conclude that a major mechanism for regulation of neutrophil production involves secretion of IL-23 that is regulated by phagocytosis of apoptotic neutrophils. "The discovery of neutrophil-regulating cells suggests new ways to manipulate the inflammatory system and neutrophil product...

White blood cell waste disposal system plays critical regulatory role

...siderably. The researchers conclude that a major mechanism for regulation of neutrophil production involves secretion of IL-23 that is regulated by phagocytosis of apoptotic neutrophils. "The discovery of neutrophil-regulating cells suggests new ways to manipulate the inflammatory system and neutrophil product...
Phagocytosis in Biological Technology

Th1 and Th2 Balance, Regulation, and Involvement in Disease

...y cytokines like IFN-γ, IL-2, and TNF-β. Th1 cells are involved in cell-mediated immunity. The cytokines produced by Th1 cells stimulate the phagocytosis and destruction of microbial pathogens. Several chronic inflammatory diseases have been described as Th1 dominant diseases i.e. multiple scl...
Phagocytosis in Biological Definition

Alga

...nucleus . It has been suggested that the euglenid chloroplasts only have three membranes because they were acquired through myzocytosis rather than phagocytosis . The remaining algae all have chloroplasts containing chlorophylls a and c . The latter chlorophyll type is not known from any prokaryotes or p...

Antibody

... against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation (immunology) of their toxins. There are 4 subclasses: ... agglutination and precipitation of antibody-antigen products prime for phagocytosis by macrophages and other cells, block viral receptors and stimulate othe...

Antigen

...enous antigens are antigens that have entered the body, e.g., by inhalation, ingestion, or injection. These antigens are taken up by endocytosis or phagocytosis into the antigen presenting cells (APCs), and degraded into fragments. The fragments are then presented on the surface of APCs by class II histocom...

Immune system

...acrophages are thought to mature continuously from circulating monocytes. phagocytosis involves chemotaxis , where phagocytic cells are attracted to microorganis...tein , for example, binds to the C-protein of S. pneumoniae - enhances phagocytosis and activates complement), lysozyme and the complement system . Com...

Alga

...nucleus . It has been suggested that the euglenid chloroplasts only have three membranes because they were acquired through myzocytosis rather than phagocytosis . The remaining algae all have chloroplasts containing chlorophylls a and c . The latter chlorophyll type is not known from any prokaryotes or p...

Protist

...re traditionally divided based on similarities to the higher kingdoms. The animal-like protozoa are mostly single-celled, motile, and feed through phagocytosis , though there are numerous exceptions. They are usually only 0.01-0.5 mm in size, and are generally too small to be seen without a microscope. They...

Protist

...re traditionally divided based on similarities to the higher kingdoms. The animal-like protozoa are mostly single-celled, motile, and feed through phagocytosis , though there are numerous exceptions. They are usually only 0.01-0.5 mm in size, and are generally too small to be seen without a microscope. They...

Pseudopod

...flagella and cilia ). Sensory role Pseudopods also capture prey phagocytosis . phagocytosis pseudopods have arisen in a number of different protist groups, but also ...

Vacuole

...le 3 Vacuoles in budding yeast cells 4 References Vacuoles in protists Some protists and macrophages use food vacuoles in phagocytosis —the intake of large molecules, particles, or even other cells, by the cell for digestion . A contractile vacuole is used to pump excess wa...
Phagocytosis in Biological Dictionary

Phagocytosis

Phagocytosis is the cellular process of phagocytes and protists of engulfing solid particles by the cell membrane to form an internal phagosome. Phagocytosis is a specific form of endocytosis involving the vesicular... process by which certain living cells called phagocytes ingest ...

Plasmalemma

...and a trilaminar plasmalemma . ... and the midgut apical plasmalemma in these ... ... penetrating through the host cell plasmalemma or by phagocytosis (15, 54, 95, ... disappears, and its outer membrane becomes the plasmalemma of the progeny cells. ... Where present it was clearly limited to ...

Phagocytes

...hagocytes . Citations 1-10 of 972 total displayed. ... Phagocytes . Phagocytes , Granulocytes, and Myelopoiesis. Platelets and Thrombopoiesis ... phagocytosis Greek -phagos, one that eats; kytos, cell, process of ingestion of matter by cells known, in this context, as phagocytes ... (b) Included among ...

Endosymbiosis

... endosymbiosis from the Merriam-Webster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and word games. ... symbiosis phagocytosis microbiology endosymbiosis by idoerg on ... Did an ancient chlamydial endosymbiosis facilitate the establishment of primary plastids? ... Br...

Endocytosis

...endocytosis reduce our serum levels of cholesterol? ... There are two types of endocytosis : pinocytosis, the engulfing and digestion of ... phagocytosis - phagocytosis: phagocytosis: see endocytosis . ... Receptor-Mediated Endocytosis ... receptor is then engulfed by endocytosis . ... Recepto...

Cytoskeleton

...teins ... Cytoskeleton . Glycolysis. Microtubules. Microfilaments. Intermediate Filaments ... Dynamic Redistribution of the Cytoskeleton during phagocytosis - Provides a ... Nature Milestones in Cytoskeleton also comprises a Collection of selected ... The online-only Library contains cytoskeleton -re...

Apoptosis

.... Outlines the mechanisms of cell suicide. apoptosis n. Disintegration of cells into membrane-bound particles that are then eliminated by phagocytosis or by ... Apoptosis is a process by which cells in ... This chapter of the Promega Protocols and Applications Guide is a resource for the most...
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