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Peroxidase in Medical News

A potential drug for ischemia/reperfusion related liver injury

...han in the I-R/Resveratrol group. Malondialdehyde levels and the hepatic injury score decreased, while superoxide dismutase, catalase, and glutathione peroxidase levels increased in group 4 compared to group 3. In group 4, histopathological changes were significantly attenuated in resveratrol treated livers. ...

Parkinsons Disease Mechanism Identified

... In their new studies, the researchers analyzed neurons to determine that Cdk5 regulates yet another enzyme called Prx2. This enzyme is known as a peroxidase and acts to render harmless the chemically active reactive oxygen species that are produced inside mitochondria in the process of generating energy fo...

Alteon Initiates Phase 2 Trial of ALT-2074 in Diabetes and Haptoglobin 2-2

... Alteon Inc. announced today that it has dosed its first patient in a 60-patient Phase 2 clinical trial (Study 201) of ALT-2074, its lead glutathione peroxidase mimetic, in diabetic patients with a variant of haptoglobin that renders them at high risk for cardiovascular complications. This dose escalati...

National Institute Of Health & Family Welfare To Commercialize Its Products

...e value in those Elisa kits that are based on the use of enzyme horseradish peroxidase as label. The imported kits wherein horseradish peroxidase enzyme used are not thermo stable (can not with stand higher temperature of...

Molecular Computer Developed To perform Calculations From Within Human Body

...cal applications and could, in the future, be implanted into humans. The researchers used two enzymes, glucose dehydrogenase (GDH) and horseradish peroxidase (HRP), to trigger two interconnected chemical reactions, the online edition of New Scientist reported. According to the report, enzymes are alread...
Peroxidase in Medical Products

Thyroid Peroxidase (TPO) Antibody

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Thyroid Peroxidase (TPO) Autoantibody - ELISA

Description: ELISA kit for the quantitative determination of autoantibodies to thyroid peroxidase (TPO) in serum...
Company:KRONUS

Thyroid Peroxidase (TPO) Autoantibody - RIA

Description: RIA kit for the quantitative determination of autoantibodies to thyroid peroxidase (TPO) in serum....
Company:KRONUS

Kallestad Anti-Thyroid Peroxidase (TPO)

Description: Anti-Tg and Anti-TPO are two major autoantibodies implicated in autoimmune related thyroiditis and aid in the differential diagnosis of Hashimoto's thyroiditis and Graves' disease....
Company:Bio-Rad Laboratories

TPO (Ab) EIA Thyroid Function 012-MDKAM-1 Thyroid Peroxidase

Description: The anti-TPO test kit is a solid phase enzyme immunometric assay (ELISA) in microplate format. It is designed for the quantitative measurement of autoantibodies directed against thyroid peroxidase (TPO) in serum or plasma. The microplate is coated with human thyroid-peroxidase. Phase 1: Calibrat...
Company:ALPCO Diagnostics

TPO (Ab) RIA Thyroid Function 014-HD-90.1 Thyroid Peroxidase

Description: DYNOtest anti-TPOn is a competitive radioimmunoassay for the quantitative determination of autoantibodies to thyroid peroxidase (TPO) in human serum using the coated tube technique. For the DYNOtest anti-TPOn BRAHMS employs exclusively enzymatic active native TPO from human thyroi...
Company:ALPCO Diagnostics

ImmunoDOT Thyroid Autoimmunity Test

Description:...roid Autoimmunity Test is an enzyme immunoassay (EIA) test for screening and detection of autoantibodies against human thyroglobulin and human thyroid peroxidase (microsome) in serum and heparinized whole blood and is used as an aid in the diagnosis of thyroid disorders. Autoimmune thyroid gland disorders are c...
Company:GenBio

ImmunoWELL TPO IgG Quantitative Test

Description:...he ImmunoWELL TPO IgG Quantitative Test is a quantitative enzyme immunoassay (EIA) for screening and detection of autoantibodies against human thyroid peroxidase (microsome) in serum and is used as an aid in the diagnosis of thyroid disorders....
Company:GenBio

DHEA-S ELISA

Description:...n principle and the microplate separation. An unknown amount of DHEA-S present in the sample and a fixed amount of DHEA-S conjugated with horse-radish peroxidase compete for the binding sites of a polyclonal DHEA-S antiserum coated onto the wells. After one hour incubation the microtiterplate is washed to stop ...
Company:Calbiotech, Inc.

Free Estriol (E3) EIA Reproductive Markers 020-DR-1612

Description:...precoated in the microwells. After one hour, the free estriol horseradish peroxidase and unbound estriol are washed from the wells with buffer. Substrate is added to the antibody bound estriol horseradish peroxidase which is immobilized in the wells. After a brief incubation period a stop...
Company:ALPCO Diagnostics

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Peroxidase in Biological News

Pitt researchers create non-toxic clean-up method for potentially toxic nano materials

...ucts, from electronics to plastics. A Pitt research team has found that carbon nanotubes deteriorate when exposed to the natural enzyme horseradish peroxidase (HRP), according to a report published recently in Nano Letters coauthored by Alexander Star, an assistant professor of chemistry in Pitt's School o...

Oxidative stress: Mechanism of cell death clarified

...ve stress, mice and cells were generated that specifically lack glutathione peroxidase 4 (GPx4), which is emerging as one of the most important GSH dependent enzy...were amazed to find that in cells lacking either glutathione or glutathione peroxidase 4, a distinctive signaling pathway is engaged, which causes cell death. The...

Rice University researchers create 'nanorice'

...trigger Alzheimer's disease. The discovery of the formation of amyloid-beta peroxidase provides a clear picture of why cells die in the brain of Alzheimer's patie...enge is to develop drugs that directly and selectively target the excessive peroxidase of amyloid-beta, which could lead to the first significant therapy for Alzh...

Alzheimer's study first to explain death of brain cells

...trigger Alzheimer's disease. The discovery of the formation of amyloid-beta peroxidase provides a clear picture of why cells die in the brain of Alzheimer's patie...enge is to develop drugs that directly and selectively target the excessive peroxidase of amyloid-beta, which could lead to the first significant therapy for Alzh...
Peroxidase in Biological Technology

High Sensitivity, Wide Dynamic Range, Horseradish Peroxidase (HRP) ELISA Using the LMax Microplate Luminometer (MaxLine Application Note #41)

Evelyn McGown, Ph.D. and Michael Su, M.S. Molecular Devices Corporation, 8/00 INTRODUCTION Immunoassays have traditionally employed colorimetric indicators. As such, multiple dilutions of samples were necessary to ensure that they fell within the dynam...

Pitt researchers create nontoxic clean-up method for potentially toxic nano materials

...ucts, from electronics to plastics. A Pitt research team has found that carbon nanotubes deteriorate when exposed to the natural enzyme horseradish peroxidase (HRP), according to a report published recently in Nano Letters coauthored by Alexander Star, an assistant professor of chemistry in Pitt's School o...

Synvista Therapeutics Posts Letter to Stockholders on Web Site

... SYI-2074 in the treatment of psoriasis. -- Chosen a lead Glutathione peroxidase mimetic generated in a discovery collaboration with Provid Pharmaceuti... area in October 2008. We also have developed a new family of glutathione peroxidase mimetics with properties that may be more attractive than SYI-2074 in treat...

New Tools for Making and Processing Protein Microarrays.

...y-based assays1,2. These multi-step protocols provide for signal amplification through the use of tyramide derivatives as a substrate for horse radish peroxidase (HRP). This catalyzes a reaction to form activated tyramides which rapidly bind to multiple tyrosine residues in any proteins that are immediately adj...

Bio-Plex Cytokine Immunoassays and ELISA: Comparison of Two Methodologies in Testing Samples From Asthmatic and Healthy Children, Rev A

...1 and a polyclonal detection antibody (goat anti-human). The detection antibodies were biotinylated and streptavidin-horseradish peroxidase was the enzyme label reagent. Results and Discussion Correlation between the Bio-Plex assay and ELISA was evaluate...

Detection of mRNAs on Cryosections of the Cardiovascular System Using DIG-Labeled RNA Probes

... performed on a shaking platform. The peroxidase staining procedure was performed according to the manufacturers recommend...ial cells: von Willebrand factor, Sigma; macrophages: CD68, DAKO) and a peroxidase staining procedure (Vectastain Elite Kit, Vector Laboratories). Approxima...

Genetic Reporter Systems

... is detected in two steps via a digoxigenin- coupled anti-hGH antibody and a peroxidase-coupled anti-digoxigenin antibody. Bound peroxidase is quantified by incubation with a substrate. Another secreted reporter protein is the SEAP (secreted alkaline phosphatase). ...

Genetic Reporter Systems

... is detected in two steps via a digoxigenin- coupled anti-hGH antibody and a peroxidase-coupled anti-digoxigenin antibody. Bound peroxidase is quantified by incubation with a substrate. Another secreted reporter protein is the SEAP (secreted alkaline phosphatase). ...

Enzyme Immunoassay for Studying Intracellular Levels of cAMP

...AMP antibodies are combined with the sample and cAMP-horseradish peroxidase conjugate (tracer) and applied to the microtiter well. Samples c...ric plate reader at 450 nm. Since the amount of cAMP-horseradish peroxidase bound to rabbit anti-cAMP antibody is inversely proportional to ...
Peroxidase in Biological Products

Rabbit Anti-pCrosstide Polyclonal Antibody, Horseradish Peroxidase Conjugated from Abcam

Description: Rabbit polyclonal to pCrosstide (HRP) ( Abpromise for all tested applications)....
Company:Abcam

Rabbit Anti-Shigella Polyclonal Antibody, Horseradish Peroxidase Conjugated from Abcam

Description: Rabbit polyclonal to Shigella (HRP) ( Abpromise for all tested applications)....
Company:Abcam

Rabbit Anti-Phosphothreonine-X-Phosphotyrosine Polyclonal Antibody, Horseradish Peroxidase Conjugated from Abcam

Description: Rabbit polyclonal to Phosphothreonine-X-Phosphotyrosine (HRP) ( Abpromise for all tested applications)....
Company:Abcam

Donkey Anti-Human Lactoferrin Antibody, Horseradish Peroxidase Conjugated from Biomeda Corporation

Description: Anti-HumanLactoferrin...
Company:Biomeda Corporation

Sheep Anti-Human Factor XIII Antibody, Horseradish Peroxidase Conjugated from CEDARLANE Laboratories Limited

Description: Anti-Human Factor XIII HRPO (Polyclonal) (sheep IgG)...
Company:CEDARLANE Laboratories Limited

Ultrastreptavidin (USA) Horseradish peroxidase (HRP) 150 Test, Murine, Detection Kit (SIGNET) from Covance Research Products, Inc

Description: Each Signet Level 2 Detection System combines the indirect labeling technique, the avidin-biotin chemical bonding principle and Signets unique formulation of ultra Streptavidin to provide sensitivity, specificity and reliablility. Signet reagents will achieve excellent quality immunostaining in bot...
Company:Covance Research Products, Inc

Ultrastreptavidin (USA) Horseradish peroxidase (HRP) 500 Test, Rabbit, Detection Kit (SIGNET) from Covance Research Products, Inc

Description: Each Signet Level 2 Detection System combines the indirect labeling technique, the avidin-biotin chemical bonding principle and Signets unique formulation of ultra Streptavidin to provide sensitivity, specificity and reliablility. Signet reagents will achieve excellent quality immunostaining in bot...
Company:Covance Research Products, Inc

Ultrastreptavidin (USA) Horseradish peroxidase (HRP) 1000 Test, Multi-Species, DAB Detection Kit (SIGNET) from Covance Research Products, Inc

Description: Each Signet Level 2 Detection System combines the indirect labeling technique, the avidin-biotin chemical bonding principle and Signets unique formulation of ultra Streptavidin to provide sensitivity, specificity and reliablility. Signet reagents will achieve excellent quality immunostaining in bot...
Company:Covance Research Products, Inc

Ultrastreptavidin (USA) Horseradish peroxidase (HRP) 50 Test, Murine, DAB Detection Kit (SIGNET) from Covance Research Products, Inc

Description: Each Signet Level 2 Detection System combines the indirect labeling technique, the avidin-biotin chemical bonding principle and Signets unique formulation of ultra Streptavidin to provide sensitivity, specificity and reliablility. Signet reagents will achieve excellent quality immunostaining in bot...
Company:Covance Research Products, Inc

Ultrastreptavidin (USA) Horseradish peroxidase (HRP) 50 Test, Multi-Species, AEC Detection Kit (SIGNET) from Covance Research Products, Inc

Description: Each Signet Level 2 Detection System combines the indirect labeling technique, the avidin-biotin chemical bonding principle and Signets unique formulation of ultra Streptavidin to provide sensitivity, specificity and reliablility. Signet reagents will achieve excellent quality immunostaining in bot...
Company:Covance Research Products, Inc

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Peroxidase in Biological Definition

Down syndrome

... the hypothesis says that once SOD activity increases disproportionately to enzymes responsible for removal of hydrogen peroxide (e.g., glutathione peroxidase ), the cells will suffer from a peroxide damage. Some scientists believe that the treatment of Down syndrome neurons with free radical scavengers c...

Enzyme

...where oxygen is reduced to water Cytochrome c peroxidase takes reducing equivalents from cytochrome c an...eurotransmitter GABA in the brain Glutathione peroxidase : protects cells by converting hydrogen peroxide ...he first step in the production of polyamines peroxidase : the group of enzymes that can convert hydrogen ...
Peroxidase in Biological Dictionary

Streptavidin

...m the bacterium ... This Cell Signaling Technology product is useful for the detection of biotinylated proteins (1,2). Conjugation of horseradish peroxidase (HRP) to streptavidin is ... A 52.8 kDa non-glycosylated protein with a very high affinity for biotin. ... unit is defined as the amount of St...

Lysosomes

..., carbohydrates, proteins, and ... Lysosomes are often budded from the membrane of the Golgi apparatus, but in some ... Explain the importance of peroxidase generation and degradation in lysosomes ... They early endosomes (primary lysosomes ) may fuse with phagocytic or other ... Christian de Duve wa...

Base pair

...se pair ? Meaning of base pair as a legal term. What does base pair mean in law? ... A 20 base pair duplication in the human thyroid peroxidase gene ... Base pairs hold the actual information in DNA and RNA -- somewhat analogous to ... Every once in a while, a base pair substitut...
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