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Peripherally in Medical News

Following CMS Cuts to Reimbursement for Medical Errors, New Devices Aimed at Reducing Nosocomial Infections Emerge

...dwelling CVCs and dialysis catheters, which are associated with higher risks of infection, 2009 saw the introduction of the first antimicrobial-coated peripherally inserted central venous catheter (PICC) from Cook Medical. The launch of the first antimicrobial PICC is the latest development in a more widespread t...

New PICC Mimics Nature

... A novel coating being used on a new peripherally inserted central catheter (PICC) from r4 Vascular mimics the cell layer fou...ple Grove, MN (Vocus) July 1, 2009 -- A novel coating being used on a new peripherally inserted central catheter (PICC) from r4 Vascular mimics the cell layer f...

New Vascular Access Medical Devices Launched by Navilyst Medical

...focus for the PICC Convenience Kitting program is on the bedside placement segment which accounts for over two-thirds of the approximately two million peripherally Inserted Central Catheters (PICCs) that are sold in the U.S. annually. The program provides clinicians and hospitals the catheter and accessory choice...

The Endocrine Society Publishes White Paper Calling for Greater Minority Participation in Clinical Research

...dical schools should offer training in Good Clinical Research Practice and Cultural Competencies to all trainees and staff members who may directly or peripherally engage in clinical research. This activity, including development of the white paper, was funded by a grant from the Robert Wood Johnson Foundatio...

Neuromed Appoints Jeffrey Arcara and Gene Wright to Senior Management Team

... Executive Director of Marketing at Wyeth, where he was leading a commercial launch team for the investigational drug subcutaneous methylnaltrexone, a peripherally acting mu-opioid receptor antagonist for the treatment of opioid-induced constipation in patients receiving palliative care. Prior to Wyeth, Mr. Arcar...

Nektar's Leading PEGylation and Pulmonary Technology Platforms Featured at R&D Day in New York

...rapy to treat opioid-bowel dysfunction (OBD), including opioid- induced constipation, in patients using opioids for management of pain. NKTR- 118 is a peripherally acting opiod receptor antagonist. PEGylation of naloxol was designed to alleviate constipation while reducing it's entrance into the CNS and preservin...

Genaera Announces Formation of Scientific Advisory Board for Obesity Drug Candidate Trodusquemine (MSI-1436)

...tabolism and clinical pharmacology. About Trodusquemine (MSI-1436) Trodusquemine (MSI-1436) is the first drug candidate that acts both centrally and peripherally to selectively inhibit the established and validated enzyme target, protein tyrosine phosphatase 1B (PTP-1B). The dual locations of MSI-1436 action ma...

Ambiguous Efficacy Of Opioid Drugs In Chronic Inflammatory Joint Pain Relief

...he therapy did, however, provoke a dramatic reduction in short-term joint hypersensitivity. These findings begin to explain the ambiguous efficacy of peripherally administered -opioid drugs in controlling chronic inflammatory joint pain. ...
Peripherally in Medical Technology

Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions

...We are looking forward to expanding our metabolic disease pipeline by adding antisense drugs to treat obesity, an area with great unmet need where our peripherally acting drugs could have significant therapeutic utility without the potential for central nervous system toxicities that plague many centrally acting ...

Genaera Begins Phase 1b Trial of Trodusquemine (MSI-1436) in Overweight and Obese Type 2 Diabetics

...) in overweight and obese type 2 diabetics. MSI-1436 is a novel therapeutic for the treatment of type 2 diabetes and obesity which works centrally and peripherally to regulate insulin and leptin pathways through the highly selective inhibition of its novel target enzyme, PTP-1B. Study 102 will establish ...

Isis Highlights Robust Drug Portfolio for Diabetes and Obesity at ADA Conference

...o quickly validate novel targets that provide exciting new approaches to treat metabolic diseases. In particular, obesity is an area where we feel our peripherally acting drugs rather than centrally acting drugs could have a profound impact on the activity and tolerability of anti-obesity therapy. Furthermore, ou...

Wyeth and Progenics Announce Preliminary Clinical Trial Results for RELISTOR Oral and Intravenous Formulations

...STOR," says Gary L. Stiles, M.D., Executive Vice President, Chief Medical Officer, Wyeth Pharmaceuticals. About RELISTOR and Opioids RELISTOR is a peripherally acting mu-opioid receptor antagonist that counteracts the constipating effects of opioid pain medications in the gastrointestinal tract without affect...

Genaera Begins Dosing Second Phase 1 Trial of Type 2 Diabetes and Obesity Compound Trodusquemine (MSI-1436)

..., in overweight and obese type 2 diabetics. MSI-1436 is a novel therapeutic for the treatment of type 2 diabetes and obesity which works centrally and peripherally to regulate insulin and leptin receptor signaling through inhibition of its novel target enzyme PTP-1B. Study 103 is similar in design to the previo...

Genaera Corporation Provides Highlights of Positive Phase 1 Trodusquemine (MSI-1436) Data from the North American Association for the Study of Obesity Annual Meeting

...ssion, "First in Human Use of MSI-1436 (Trodusquemine), a Centrally and peripherally Acting Selective PTP1B Inhibitor," demonstrated that the drug was safe ...quemine (MSI-1436) is the first drug candidate that acts both centrally and peripherally to selectively inhibit the established and validated enzyme target, protein...

Genaera Corporation Presents Phase 1 Data for Trodusquemine (MSI-1436) at the North American Association for the Study of Obesity Annual Meeting

...d at NAASO, "First in Human Use of MSI-1436 (Trodusquemine) a Centrally and peripherally Acting Selective PTP1B Inhibitor" will be presented today from 9:00 a.m. to...quemine (MSI-1436) is the first drug candidate that acts both centrally and peripherally to selectively inhibit the established and validated enzyme target, protein...

Genaera Corporation Presents Preclinical Trodusquemine (MSI-1436) Data at the North American Association for the Study of Obesity Annual Meeting

...:00 p.m. to 2:30 p.m. to answer any questions. About Trodusquemine Trodusquemine (MSI-1436) is the first drug candidate that acts both centrally and peripherally to selectively inhibit the established and validated enzyme target, protein tyrosine phosphatase 1B (PTP-1B). The dual locations of MSI-1436 action ma...

Genaera Corporation Presents Interim Phase 1 Data for Obesity Compound Trodusquemine (MSI-1436) at IBC Conference

...s progress to broader populations." About Trodusquemine (MSI-1436) Trodusquemine (MSI-1436) is the first drug candidate that acts both centrally and peripherally to selectively inhibit the established and validated enzyme target, protein tyrosine phosphatase 1B (PTP-1B). The dual locations of MSI-1436 action ma...

Genaera Presents Preclinical Data on Trodusquemine (MSI-1436) for the Treatment of Obesity at the American Diabetes Association 67th Scientific Session

... Remove the space if one exists.) About Trodusquemine (MSI-1436) Trodusquemine (MSI-1436) is the first drug candidate that acts both centrally and peripherally to selectively inhibit the established, validated enzyme target, protein tyrosine phosphatase 1B (PTP-1B), that is central to both insulin and leptin ...
Peripherally in Medical Products

Turbo-Flo Peripherally Inserted Central Venous Catheters (PICC)

Description: Used for venous pressure monitoring, blood sampling, and administration of drugs and fluids. Turbo-Flo polyurethane PICC line sets offer: Higher Flow Rates Micropuncture Introducer Needle Biocompatible Polyurethane Material Catheter may be trimmed to patient specific a...
Company:Cook Vascular, Inc.

Alio-Prats Irrigating "Stinger"

Description:...nger" tip for dividing and chopping the nucleus. In addition, the tip is ideal for retrieving fragments from underneath the iris which can be located peripherally inside the capsular bag. The large irrigation port is directed toward the posterior capsule to provide stable fluidic control during phaco....
Company:Katena Products, Inc.

Ghrelin, Total ELISA Test

Description:... properties comparable to growth hormone releasing hormone (1), it also has powerful growth hormone independent effects (2). Administration of Ghrelin peripherally or centrally into the cerebral ventricles induces weight gain in rodents (3) and in humans, Ghrelin levels peak prior to each meal and then fall to lo...
Company:Diagnostic Systems Laboratories, Inc.
Peripherally in Medical Dictionary

Thyroxine

...e in Patients with Hypothyroidism Thyroxine information including symptoms, causes, diseases, symptoms, treatments, and other ... Thyroxine is peripherally deiodinated to form ... Hypothyroidism ... Thyroxine converts to triiodothyronine (T3), which is a more biologically active ... When thyroxine ...
Peripherally in Biological News

Umbilical cord blood cell therapy in an animal model of Alzheimer's disease

...isruption of the CD40-CD40L interaction may alleviate the key pathologic changes in the brain associated with Alzheimers disease in a report entitled, peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice. Previously, challenging obse...
Peripherally in Biological Definition

Punctuated equilibrium

...nce [on the gene pool]. New and favorable mutations are diluted by the sheer bulk of the population through which they must spread....But [in] small, peripherally isolated groups [that] are cut off from their parental stock ... selective pressures are usually intense because peripheries mark the edge of ecologic...
Peripherally in Biological Dictionary

Skeletal muscle

... nervous system. ... Iris & Light Simulations: skeletal muscle , human, H&E. Self Assessment ... Skeletal muscle fibres contain many peripherally placed nuclei. ... The striated category is subdivided further into skeletal and cardiac muscle . ... The banding pattern of skeletal muscle ...
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