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Peptides in Medical News

Food peptides activate bitter taste receptors

PHILADELPHIA (January 22, 2008) -- Researchers from the Monell Center and Tokyo University of Agriculture have used a novel molecular method to identify chemical compounds from common foods that activate human bitter taste receptors. The findings, published in the journal Biochemical and Bioph...

Potent peptides inhibit HIV entry into cells

UPTON, NY -- Based in part on protein structures determined at the National Synchrotron Light Source (NSLS) at the U.S. Department of Energy's Brookhaven National Laboratory, scientists at the University of Utah have developed new peptides that appear to be significantly more effective at blocking...

Appetite-regulating Peptides Influence Alcohol Cravings

A new study has confirmed that appetite-regulating peptides leptin and ghrelin influence alcohol cravings for some alcoholics. Craving, a powerful urge to drink, is an important contributor to the development and maintenance of alcoholism. Professor Otto Lesch of the University of...

Specific Imbalance Between Two Peptides may Cause Alzheimer's

Researchers at Rensselaer Polytechnic Institute have challenged the current theory on the causes and prevention of Alzheimers disease , suggesting that a specific imbalance between two peptides may be responsible for preventing this form of dementia. "We have found that two peptides, AB42 a...

Photos: Lumixyl(TM) Enters the Market to Improve the Appearance of Hyperpigmentation without Irritation and Side Effects

...ermalinfusion(R) for deeper tissue delivery of active ingredients and better patient outcomes. Envy is also the exclusive licensor of skin brightening peptides including Lumixyl, developed at Stanford University. The Lumixyl peptide is now also available as a topical solution for SilkPeel procedures, addressi...

Reexamination of T. rex verifies disputed biochemical remains

...ound in collagen. "In summary, we find nothing obviously wrong with the Tyrannosaurus rex [analysis from 2007]," the report states. "The identified peptides seem consistent with a sample containing old, quite possibly very ancient, bird-like bone, contaminated with only fairly explicable proteins. Hemoglob...
Peptides in Medical Technology

Photos: Peptides Discovered to Alleviate Chemotherapy Side Effects

RIVERSIDE, Calif., Nov. 20 /PRNewswire/ -- Milk. It does a body good. And now it's doing it even better than originally thought. After years of research, scientists at OncoNutrition(TM) have discovered peptides found in cow's milk that stimulate the body's own production of antioxidants. ...

Are Muramyl Peptides the Magic Bullet in Probiotics?

BOULDER, Colo., Dec. 11 /PRNewswire/ -- Magazines like Time, Newsweek, and U.S. World and News are all buzzing about the latest health trend, probiotics. Researchers have found compelling evidence that these friendly bacteria are an important key to digestive and immune health, but Eastern Eur...

Helix BioMedix to Discuss Potential of Its Proprietary Peptides at the BIO International Convention

BOTHELL, Wash., April 18, 2007 /PRNewswire-FirstCall/ -- Helix BioMedix, Inc. today announced that Timothy Falla, Ph.D, Chief Scientific Officer, will present an update on the company's new generation of small molecule peptide (lipohexapeptide) technology at the BIO International Convention. The c...

Radius' Investigational Bone Anabolic Agent, BA058, Increased Bone Mineral Density (BMD) at Key Fracture Sites in Phase 2 Clinical Trial in Postmenopausal Osteoporosis

...m, PTHrP (parathyroid hormone-related protein) and its analogs are critical peptides for promoting new bone formation. Though they act through the same receptor... play an important role in regulating bone remodeling in adults. While both peptides have demonstrated the ability to increase bone mineral density and bone str...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

...lopment are based upon the company's discovery of replikins, a new group of peptides related to the rapid replication function in viral and other diseases. The ...and predictive tools are based on the company's discovery of a new group of peptides related to rapid replication called Replikins, whose increase in concentrat...

Raptor Pharmaceuticals Receives Notices of Allowance for Two NeuroTrans(TM) Patent Applications

...and generally cover the use of its proprietary RAP peptides in the delivery of diagnostic and therapeutic agen... minimally invasive way by conjugating them to RAP peptides engineered by Raptor. Hundreds of neurodegenerativ...rotect the use of our NeuroTrans(TM) CNS targeting peptides and the extensive range of potential uses of Neuro...
Peptides in Medical Products

ALS, Total ELISA Test

Description:...n vivo. However, ALS may also be capable of IGF-independent interaction with IGFBP-3 and as such modulate the binding capacity of IGFBP-3 for the IGF peptides [11]. Jones JI et al. Endocrin Rev 16:3-34, 1995 Rosenfeld RG et al. Recent Prog Horm Res 46:99-163, 1990 Shimesaki S et al. Prog Growth Factor...
Company:Diagnostic Systems Laboratories, Inc.

Dynabeads® MyOne™ Streptavidin T1

Features:... Low charged and neutral beads, optimal for binding of proteins, peptides and antibodies Their small but uniform size presents a high surface area per mg beads and a correspondingly high capacity for the target molecule Lo...
Company:Dynal Biotech, LLC
Peptides in Medical Definition

Thymocyte

...ptosis in thymocytes with a high affinity for self peptides or MHC. This eliminates cells which would direct i...rotein able to recognise short protein sequences ( peptides ) that are presented on MHC . During the double n...l thymocytes with a high affinity for binding self peptides presented on MHC class I or class II are induced t...
Peptides in Medical Dictionary

Total protein

...n plasma compared to serum. ... Total protein Western blots for proteomics, gene discovery, & protein functional ... Protein Kits. peptides and Blocking Peptides. Recombinant Proteins. Total ... ...

Kinins

..... ... biochemical compounds > amino acids, peptides and proteins > peptides > kinins ... Resources in kinins : No resour... stimulating the ... Kinins are vasodilatory peptides liberated from the protein precursor, kininogen,...

Antimicrobial

...MP action ... 8 Factors that determine the selectivity of antimicrobial peptides ... Antimicrobial Test Laboratories is a Microbiology Laboratory Spec...OST DEFENSE PEPTIDES. ANTIVIRAL ACTIVITY ... DEVELOPMENT OF ANTIMICROBIAL peptides FOR CLINICAL ... Modulation of host antimicrobial peptide (beta-def...
Peptides in Biological News

Frog peptides block HIV in lab study

In the human brain, cells talk to one another through the routine exchange of electrical signals. But when people fall into a deep sleep, the higher regions of the brain - regions that during waking hours are a bustling grid of neural dialogue - apparently lose their ability to communicate effectiv...

Alzheimer's disease drug treats traumatic brain injury, report GUMC researchers

... nerve cells after traumatic brain injury. This secondary injury can last months, if not years, resulting in large holes within brain tissue. Amyloid peptides are produced when a long brain protein known as the amyloid precursor protein (APP) is cut in two by the enzyme beta secretase, and then cut once agai...

U Alberta researcher in same group as Darwin and Hawking

...h that centers on the identification of antibiotic peptides in bacteria. Antibiotic peptides play an important role in food preservation and ma...e, such as combating hospital-acquired infections. peptides are 1,000 to 1 million times more active than conv...

Tips from the journals of the American Society for Microbiology

...al defense system shared by all animals, activates when the body responds to foreign pathogens at an early stage of infection. Cationic antimicrobial peptides (known for their antibacterial, antifungal, antiviral, antiprotozoal and antiseptic properties) are part of the innate immune response which kills mic...

American Society for Microbiology honors George Liu

...igation of the mechanism of immunologic tolerance in a model of autoimmunity. His novel concept that the low affinity of certain autoantigenic peptides could provide a basis for the existence of autoreactive T cells in humanshad an impact on the field of autoimmunity. Dr. Liu's research t...

Comprehensive genetic study paves way for new blood-pressure medicines

... role in the biosynthesis of glucorticoid hormones, which influence the metabolism of salt. In another area on chromosome 1p36 there are genes for two peptides with natrium-expelling effects. A lesser-known gene in this area, CLCN6, codes for a chloride canal in the neurons, which was not previously associate...
Peptides in Biological Technology

Separation of Peptides by Hydrophilic Interaction Chromatography Using TSKgel Amide-80

Authors: T.J. Higley, Tosoh Bioscience LLC, Tatsunari Yoshida, Tosoh Corporation Abstract: The TSKgel Amide-80 column provides excellent selectivity for separating peptides in hydrophilic interaction chromatography due to polar carb...

Structural Analysis of Glycosylated Peptides in Complex Mixtures with Ion Trap MSn

Structural Analysis of Glycosylated Peptides in Complex Mixtures with Ion Trap MS n Shiaw-Lin Wu, Pavel Bondarenko, Tom Shaler, Paul Shieh, and William S. Hancock Protein Glycosylation ...

Efficient Primary Structure Elucidation of Disulfide-bridged Peptides

The combination of Edman sequence analysis and electrospray tandem mass spectrometry provides accurate and detailed structural data of highlyknotted spider toxins Purpose The primary structure determination of disulfide bridged peptides...

Synthetech Reports First Quarter Fiscal 2010 Results

... cGMP ) in compliance with U.S. Food and Drug Administration ( FDA ) regulations. Our products support the development and manufacture of therapeutic peptides and peptidomimetic (peptide-like) small molecule drugs from early stages of a customer's clinical development through market launch and into commercia...

Shire plc: Core Portfolio of Products Delivers 20% Sales Growth

...et losses on discontinued Jerini businesses which were either divested or closed during the second quarter of 2009, the loss on divestment of Jerini's peptides business and the write-off of the fair value less costs to sell of assets previously classified as held for sale. FINANCIAL INFORMATION TAB...

Morphotek(R), Inc. and Cancer Innovations, Inc. Announce Evaluation and Option Agreement for Therapeutic Monoclonal Antibodies

...ation and possible development as we continue to grow our therapeutic antibody portfolio." "CII has developed several monoclonal antibodies, peptides and small molecules with potential applications in the treatment of cancer and neo-vascular disorders," said Toni Gray, President and CEO of CII. "Thi...
Peptides in Biological Products

Uniform 13C, 15N, Labeling of Peptides and Proteins new from rPeptide, LLC

Description: Request Info...
Company:rPeptide, LLC

Recombinant Expression of Peptides and Proteins: from rPeptide, LLC

Description: Request Info...
Company:rPeptide, LLC

QXL 520 C2 maleimide from AnaSpec

Description:...beling proteins, the single isomers are increasingly preferred for labeling peptides and nucleotides because they give better resolution in HPLC purification th...conjugation processes. 5-TAMRA is more often used than 6-TAMRA for labeling peptides and proteins. 6-TAMRA is predominately used for labeling nucleotides and se...
Company:AnaSpec

Rabbit Anti-Human Histone H3, phospho (Ser10 / Ser28) Polyclonal Antibody, Unconjugated from Lake Placid Biologicals

Description:... Antibody specific for phosphorylattion of histone H3 that occurs during mitosis. Rabbit polyclonal serum. Antigen: Synthetic peptides derived from histone H3, phosphorylated at serines 10 or 28...
Company:Lake Placid Biologicals

Rabbit Anti-Coronin / CORO1C Polyclonal Antibody, Unconjugated from IMGENEX

Description:... Polyclonal Antibody to Coronin / CORO1C This antibody was developed against synthetic peptides corresponding to amino acids 407-420 of human CORO1C....
Company:IMGENEX

PhastGel DNA Silver Staining Kit from GE Healthcare, formerly Amersham Biosciences

Description:... PhastGel DNA Silver Staining Kit, 1. Select from homogeneous and gradient polyacrylamide gels.Separate proteins and peptides on denaturing, native, and isoelectric focusing gels.Save time and improve reproducibility with precast gels, buffer strips, and staining kits.Achieve...
Company:GE Healthcare, formerly Amersham Biosciences
Peptides in Biological Definition

Alpha helix

...It was first postulated by Linus Pauling , Robert Corey , and Herman Branson in 1951 based on the known crystal structures of amino acids and peptides and Pauling's prediction of planar peptide bonds . The amino acids in an α helix are arranged in a helical structure, about 5 wide. Eac...

Amino acid

...are biochemical building blocks. They form short polymer chains called peptides or polypeptides which in turn form structures called proteins . Twent...found together with unsaturated amino acids in lantibiotics (antibiotic peptides of microbial origin). 1-Aminocyclopropane-1-carboxylic acid ( ACC ) is a sm...

Biopolymer

... A biopolymer is a polymer found in nature. Starch , proteins and peptides , and DNA and RNA are all examples of biopolymers, in which the monomer units, respectively, are sugars , amino acids , and nucleic acids . The...

Helper T cell

... cell proliferates and differentiates into activated T H cells and memory T H cells. Activated T H cells secrete cytokines , proteins or peptides that stimulate other lymphocytes ; the most common is interleukin-2 (IL-2), which is a potent T cell growth factor. Activated, proliferating T H...

Hormone

...atecholamines and thyroxine . Peptide hormones consist of chains of amino acids. Examples of small peptide hormones are TRH and vasopressin . peptides composed of scores or hundreds of amino acids are referred to as proteins. Examples of protein hormones include insulin and growth hormone. Steroid...

Immune system

...ls that kill virally-infected cells, contain surface-mounted receptors that they use to determine if a given cell is virally infected by reading the peptides displayed on its MHC molecules. During their development, T cells are tested for self-reactivity. If a given cell contains receptors that bind st...
Peptides in Biological Dictionary

Peptides

Peptides are short polymers formed from the linking, in a defined order, of α-amino acids. The link between one amino acid residue and the next is known as an amide bond or a peptide bond. Antimicrobial peptides are an evolutionarily conserved component of the innate immune response...

Spliceosome

... The spliceosome is comprised of five small nuclear RNAs (snRNAs)—U1, U2, U4, U5, ... In determining the list of spliceosome proteins, we used peptides that ... Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disci...

Signal Sequence

...effective secretion ... Signal peptide A signal peptide is a short (3-60 amino acids long) peptide chain ... sources refer to signal peptides as only the pre- sequence that targets the ... The signal sequence is immediately cleaved from the polypeptide once it has been ... This s...

Seminiferous tubules

... seminiferous tubules at specific stages of the spermatogenic. cycle. ... of seminiferous tubules in vitro (Niemi & Kormano 1965) ... peptides on seminiferous tubules . G C Harris and H D Nicholson ... seminiferous tubule contractility ... seminiferous tubules in vitro (Niemi &am...

Reducing agent

.... Solution and solid-phase reducing agents , such as TCEP, DTT, mercaptoethanol and mercaptoethylamine, for reduction of disulfide-containing peptides and proteins. ... is a potent, water-soluble, odorless reducing agent that is a popular alternative to DTT ... Crosslinking and Protein Modifi...

Proteins

.... Proteins , from the Greek proteios, meaning first, are a class of organic ... Proteins are generally regarded as beneficial, ... Continue to peptides & Proteins ... You've probably heard that proteins are important nutrients that help ... Proteins are worker molecules that are necessary...
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