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Penicillin in Medical News

Pfizer's work on penicillin for World War II becomes a National Historic Chemical Landmark

The development of deep-tank fermentation by Pfizer which enabled the mass production of penicillin for use in World War II was designated a National Historic Chemical Landmark by the American Chemical Society (ACS) in a special ceremony in Brooklyn, N.Y., on June 12, 2008. The development o...

Research could put penicillin back in battle against antibiotic resistant bugs that kill millions

Research led by the University of Warwick has uncovered exactly how the bacterium Streptococcus pneumoniae has become resistant to the antibiotic penicillin. The same research could also open up MRSA to attack by penicillin and help create a library of designer antibiotics to use against a range o...

Patients often assume wrongly that they are allergic to penicillin

A team of researchers who reviewed medical literature on the accuracy of penicillin allergies has come out with a startling expose!!!! Nearly 80% of people who claim that they are allergic to penicillin actually are under the misconception that they are allergic to the drug. The researchers l...

School Closures May Not Be Necessary When Swine Flu Strikes

...r those people and a hardship on the families, working parents -- providing babysitters and so on for someone who has strep throat and is treated with penicillin and is ready to go back to school in a day or two." Beeber noted that it is relatively quick and easy to identify strep throat, however, and the fl...

Blue Cross and Blue Shield of Illinois Urges Constant Vigilance Against Growing Threat of Killer 'Superbug'

...biotic-resistant strain of the microorganism that causes "staph" infections, MRSA originally referred just to staph bacteria resistant to methicillin, penicillin and related antibiotics. Once considered under control, MRSA has rebounded to the point it's a huge health care headache all over the world. "Wh...

Group B Strep Screening Guidelines Sparing Newborns

... Greenberg explained. "It requires at least one and preferably two doses of penicillin more than four hours before delivery so it has time to have an effect." ...liver too quickly to benefit from antibiotics and women who are allergic to penicillin (although there are other treatment options for these women). There is ...

Omega-3 EPA: Treatment for a Heart Condition

... clots. Roxana would face the ongoing risk that a clot could form again. At the young age of 12 she was told that she would need a life-long course of penicillin (to prevent a relapse of the throat infection which brought on rheumatic fever) and aspirin (to thin the blood). Troubled at the idea of the asso...

Advanced Life Sciences Announces Posting of Briefing Documents for FDA Advisory Committee Meeting on Restanza(TM) (cethromycin)

...ing annually. Macrolides and penicillins are currently the front-line treatments for respiratory tract infections such as CAP. As macrolide and penicillin resistance grows and has the potential to cause more clinical failures, there is a need for new antibiotics with unique mechanisms of action that can ...

Sagent Pharmaceuticals Announces U.S. FDA Approval of Azithromycin for Injection

...eutical company. Strides manufactures pharmaceutical formulations in various dosage forms including sterile injectables with dedicated facilities for penicillin and penems, cephalosporins, oncolytics and lyophilized injectable products. The company also manufactures pharmaceutical formulations in oral dosage ...

Rep. Slaughter Reintroduces Bill to Help Fight Antibiotic Resistance Crisis by Combating Misuse of Antibiotics in Animal Agriculture

...n that holds the FDA accountable for conducting those reviews." The bill would review the safety when antibiotics important in human medicine, such as penicillin and tetracycline, are used as additives to animal feed. "More and more Americans are dying of superbug infections because antibiotic treatment h...
Penicillin in Medical Technology

Advanced Life Sciences Announces Outcome of FDA's Anti-Infective Drugs Advisory Committee Review of Restanza(TM) (cethromycin)

...ing annually. Macrolides and penicillins are currently the front-line treatments for respiratory tract infections such as CAP. As macrolide and penicillin resistance grows and has the potential to cause more clinical failures, there is a need for new antibiotics with unique mechanisms of action that can ...

(RED) to Launch New Way for People to Get Music in Their Lives; Weekly Delivery of Great Music Helps to Save Lives in Africa

...will generate enough money annually to provide a person living with HIV with antiretroviral treatment for one year. "Don MacKinnon just might be the penicillin the ailing music business needs. He is an innovator by nature and I have no doubt that some of the music software we are working on at (RED) will help...

FDA Approves MiddleBrook's Amoxicillin PULSYS for Pharyngitis/Tonsillitis in Adolescents and Adults

...nsure better first- line therapy compliance with a penicillin class of antibiotic." Clinical Trial Results Sum...ablet for a period of 10 days to 250 milligrams of penicillin dosed four times daily, for a total of one gram pe...actic) reactions have been reported in patients on penicillin therapy. These reactions are more likely to occur ...

Cepheid Launches New GeneXpert(R) Tests in Europe for Simultaneous, Rapid Detection of Staphylococcus Aureus and Methicillin Resistant Staphylococcus Aureus

...ally avoiding clinical false-positive MRSA results. While SA infections are generally treatable with common antibiotics, MRSA is resistant to numerous penicillin and cephalosporin antibiotics. "Staphylococcus aureus is a major cause of bloodstream infection, associated with substantial mortality and healthcar...

Arpida Announces Promising Results of "First-In-Man" Studies With AR-709

...umoniae is the most feared bacterium that causes pneumonia in the community setting. Since the first reports of Streptococcus pneumoniae resistance to penicillin in 1967, the number of multiple antibiotic resistant organisms has rapidly increased world-wide, reaching peaks of 80% in regions of some countries in...

Targanta Reports Improved Ability of Oritavancin to Stop Bacteria Growth In Vitro Compared With Other Glycopeptide Antibiotics

...eumonia. S. pneumoniae bacteria have been uniformly susceptible to penicillin in the past; however, as multi-drug resistant strains become more prevalent, first-line therapies such as penicillin are not always effective, and advanced agents are being explored t...

Cethromycin Achieves Primary Endpoint in Pivotal Phase 3 Pneumonia Clinical Trial

...ccurring annually. Macrolides and penicillins are currently the first-line treatments for respiratory tract infections such as CAP. As macrolide and penicillin resistance grows and has the potential to cause more clinical failures, there is a need for new antibiotics with unique mechanisms of action, which ca...
Penicillin in Medical Products

Allergen, Drugs, Penicillin V (minor)

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Allergen, Drugs, Penicillin G (major)

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Antibiotic Level, Penicillin

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

MRSA Latex Test for PBP2

Description:...istant S. aureus and methicillin resistant coagulase-negative staphylococci in only 15 minutes. The NEW, FDA cleared, MRSA Latex Kit for PBP2/ detects penicillin Binding Protein 2/ (PBP2/) in isolates of Staphylococcus aureus and coagulase-negative staphylococci. PBP2/ is a protein coded by the mecA gene and is...
Company:Hardy Diagnostics

Gentamicin Sulfate: Liquid

Description:...bosomes. Its suggested working concentration of 50 mg/L is generally non-toxic to viruses and mammalian cells, thereby making a gentler alternative to penicillin and steptomycin. While it is useful for treating persistent contaminants, it is also beneficial for extended virus and tissue culture studies due to t...
Company:CellGro by Mediatech

Gibco Penicillin-Streptomycin-Neomycin (PSN) Antibiotic Mixture (100X), liquid

Description:... Contains 5 mg of penicillin, 5 mg of streptomycin, and 10 mg of neomycin/ml utilizing penicillin G (sodium salt), streptomycin sulfate, and neomycin sulfate in 0.85% saline....
Company:Invitrogen

Penicillin Streptomycin Solution: 5,000 I.U. Penicillin, 5,000 g/mL Streptomycin

Description:... A combination of penicillin and streptomycin which is effective against most gram positive and gram neg...The sterile solutions are prepared in water at concentrations of 5,000 I.U. penicillin and 5,000 g/mL Streptomycin or 10,000 I.U. Penicillin/10,000 g/mL Streptomy...
Company:CellGro by Mediatech

Gibco Antibiotic-Antimycotic (100X), liquid

Description:... Contains 10,000 units of penicillin (base), 10,000 g of streptomycin (base), and 25 g of amphotericin B/ml utilizing penicillin G (sodium salt), streptomycin sulfate, and amphotericin B as Fungizone Anti...
Company:Invitrogen

Gentamycin Sulfate: Powder

Description:...bosomes. Its suggested working concentration of 50 mg/L is generally non-toxic to viruses and mammalian cells, thereby making a gentler alternative to penicillin and steptomycin. While it is useful for treating persistent contaminants, it is also beneficial for extended virus and tissue culture studies due to t...
Company:CellGro by Mediatech

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Penicillin in Medical Dictionary

Strep throat

...throat , also known as Streptococcal pharyngitis or Streptococcal sore ... Conventional treatment of strep throat utilizing antibiotics like penicillin and ... ...

Ophthalmia Neonatorum

...od of study was ... Pseudo-gonococcal ophthalmia neonatorum . Paul AC, Varkki S, Mathews MS, Moses PD. ... Ophthalmia Neonatorum /diagnosis* penicillin Resistance ... Ophthalmia neonatorum : a chart review. Armstrong JH, Zacarias F, Rein MF. Cases of ophthalmia neonatorum diagnosed at Grady...

Drug allergies

...ety of South Africa (ALLSA) - Drug Allergy ... penicillin is the most common cause of a true Type I IgE medi...ergies cause minor skin rashes and hives. ... penicillin and related antibiotics are the most common caus...there is an allergic reaction to a medication. ... penicillin and related antibiotics are the most common caus...

Antibiotics

...ative of a natural substance, ... Some examples of penicillin antibiotics include penicillin V (PENVEE K, V-CILLIN) ... Antibiotics Greek...... Antibiotics have been in use since 1939 when penicillin was isolated, followed ... ... 3 Consequences ...

Antibiotic

...lution of antibiotic resistance of any previously susceptible bacterial ... The antibiotic age was ushered in with the accidental discovery of penicillin by ... Definition of antibiotic from the Merriam-Webster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and word games...
Penicillin in Biological News

Researchers describe 'implausible' chemistry that produces herbicidal compound

...how a compound is made may allow you to make an analog that can overcome that resistance," van der Donk said. "That's the game that's been played with penicillin for the last 40 years. Every time a bacterial strain becomes resistant to one penicillin, scientists tinker with the structure so that the organism is...

Duke software dramatically speeds enzyme design

...le, be possible to redesign any enzyme." That might include revamping the machinery that makes other workhorse enzymes in gramicidin's family, such as penicillin and vancomycin. Vancomycin is considered an antibiotic of last resort for patients infected by methicillin-resistant germs. And Donald's group has ...

Caltech researchers get first 3-D glimpse of bacterial cell-wall architecture

....--The bacterial cell wall that is the target of potent antibiotics such as penicillin is actually made up of a thin single layer of carbohydrate chains, linked t... the sacculus, Jensen notes, that is targeted by the antibiotic penicillin; penicillin blocks a bacterium's ability to grow and remodel the bag to fit it as the b...

American Chemical Society's Weekly PressPac -- Aug. 13, 2008

... http://www.acsannualreport.org/acsannualreport/2007 . Pfizer's work on penicillin becomes National Historic Chemical Landmark Pfizer's deep-tank fermentation a revolutionary process that enabled mass production of penicillin for use in World War II was designated a National Historic Chemical Landma...

American Chemical Society's Weekly PressPac -- July 23, 2008

... http://www.acsannualreport.org/acsannualreport/2007 . Pfizer's work on penicillin becomes National Historic Chemical Landmark Pfizer's deep-tank fermentation a revolutionary process that enabled mass production of penicillin for use in World War II was designated a National Historic Chemical Landma...

American Chemical Society's Weekly PressPac -- July 16, 2008

... http://www.acsannualreport.org/acsannualreport/2007 . Pfizer's work on penicillin becomes National Historic Chemical Landmark Pfizer's deep-tank fermentation a revolutionary process that enabled mass production of penicillin for use in World War II was designated a National Historic Chemical Landma...

American Chemical Society's Weekly PressPac -- July 9, 2008

... http://www.acsannualreport.org/acsannualreport/2007 . Pfizer's work on penicillin becomes National Historic Chemical Landmark Pfizer's deep-tank fermentation a revolutionary process that enabled mass production of penicillin for use in World War II was designated a National Historic Chemical Landma...

American Chemical Society's Weekly PressPac -- July 2, 2008

... http://www.acsannualreport.org/acsannualreport/2007 . Pfizer's work on penicillin becomes National Historic Chemical Landmark Pfizer's deep-tank fermentation a revolutionary process that enabled mass production of penicillin for use in World War II was designated a National Historic Chemical Landma...

American Chemical Society's Weekly PressPac -- June 25, 2008

... http://www.acsannualreport.org/acsannualreport/2007 . Pfizer's work on penicillin becomes National Historic Chemical Landmark Pfizer's deep-tank fermentation a revolutionary process that enabled mass production of penicillin for use in World War II was designated a National Historic Chemical Landma...

American Chemical Society's Weekly PressPac -- March 19, 2008

...us prediction about the road ahead. Mitscher notes, for instance, that miracle drugs in the 1940s and 50s failed to live up to expectations. Though penicillin promised an end to infections worldwide in 1941, reports of resistant bacteria appeared only a year later. Significant clinical resistance is now know...
Penicillin in Biological Technology

Advanced Life Sciences Receives Complete Response Letter From FDA for Restanza(TM) (Cethromycin) in Community Acquired Pneumonia

...g annually. Macrolides and penicillins are currently the front-line treatments for respiratory tract infections such as CAP. As macrolide and penicillin resistance grows and has the potential to cause more clinical failures, there is a need for new antibiotics with unique mechanisms of action that can ...

Neogen's BetaStar(R) US Dairy Antibiotic Test Approved by FDA/NCIMS

...etaStar(R) US test detects dairy antibiotic residues in the beta-lactam group (i.e., penicillin, ampicillin, amoxicillin, cephapirin, cloxacillin, and penicillin G). BetaStar US is an extremely simple dipstick test that requires only minimal training and equipment to produce consistently accurate results. ...

MiddleBrook Pharmaceuticals Hires Key Commercial Team Members

...illin compared to immediate-release amoxicillin. Moxatag is intended to provide a lower treatment dose, once- daily alternative to currently approved penicillin and amoxicillin regimens for the treatment of adults and pediatric patients 12 years and older with tonsillitis and/or pharyngitis. For more informat...

Cepheid Molecular Diagnostic Test for MRSA and S. aureus Categorized 'Moderate Complexity' by FDA

...test time-to-result thereby improving patient management decisions." MRSA is a bacterium that has become resistant to multiple antibiotics including penicillin and cephalosporins. Current culture-based lab testing methods require 24 - 72 hours to determine if a skin or soft tissue infection is caused by MRSA ...

Cepheid Receives FDA Clearance for First Rapid On-Demand Molecular Diagnostic Test for MRSA and S. aureus

... to be the molecular platform of choice for the management of HAIs." MRSA is a bacterium that has become resistant to multiple antibiotics including penicillin and cephalosporins. Current culture-based lab testing methods require 48-72 hours to determine if a skin or soft tissue infection is caused by MRSA or...

Dragon announces new product launch; increase in annual production output capacity

...lexin is a first-generation cephalosporin antibiotic but its chemical composition makes it effective in treatment of patients that show sensitivity to penicillin drugs. Cefalexin is widely used to treat urinary tract infections, respiratory tract infections, skin and soft tissue infections. In support of stra...

MiddleBrook Pharmaceuticals Reports Fourth Quarter and Full Year 2007 Results

...MOXATAG compared to immediate-release amoxicillin. MOXATAG is intended to provide a lower treatment dose, once-daily alternative to currently approved penicillin and amoxicillin regimens for the treatment of adults and pediatric patients 12 years and older with tonsillitis and/or pharyngitis. About Keflex: ...

Strong Demand Pushes up Both Prices and Sales Volumes for Dragon's Main Products

...s (APIs), and has fast emerged as a powerful player in the global API market with an average growth rate exceeding 25%. Meanwhile, since the prices of penicillin intermediates still remain high, many customers have purchased cephalosporins as alternatives, which has further pushed up the demand for 7ACA product...

Advanced Life Sciences to Present Data from Selected Cethromycin Clinical Trials at the 45th Annual Meeting of the Infectious Diseases Society of America

...Halls G-H Session 051 "Antimicrobial Agents" -- Poster 442--A Phase 3 Comparative Study of the Safety & Efficacy of Cethromycin 150 mg QD and penicillin V 500 mg TID for the Treatment of Streptococcal Pharyngitis/Tonsillitis -- Poster 443--Assessment of the Pharmacokinetic Interaction between ...

The measurement of DNA condensation and mitochondrial changes during apoptosis and necrosis in cell based assays

... 5 µg/ml Transferrin, 5 µg /ml Selenium, 10 nM Dexamethasone, 2 % v/v fetal calf serum, 10 mM HEPES, 50 U/ml penicillin G, 50 µg/mlStreptomycin sulfate. All tissue culture reagents were obtained from Gibco BRL, UK unless otherwise st...
Penicillin in Biological Definition

Alexander Fleming

...lysozyme and isolated the antibiotic substance penicillin from the fungus Penicillium notatum . Bi...nderestimated. Fleming issued a publication about penicillin in the British Journal of Experimental Pathology i...Ernst Boris Chain developed a method of purifying penicillin to a form that was useful for medical treatment of...

Antibiotic

.... The first effective antibiotic discovered was penicillin . French physician Ernest Duchesne noted in his ...purify the compound (the beta-lactam ring in the penicillin molecule was not stable under the purification met...aureus , which could be treated successfully with penicillin in the 1940s and 1950s. At present, nearly all st...

Antibiotic resistance

...tic pressure. It was the first bacterium in which penicillin resistance was found -- in 1947, just four years ... faecium is another superbug found in hospitals: penicillin resistance was seen in 1983, vancomycin resistance...as penicillin-resistant gonorrhea . Resistance to penicillin substitutes is also known beyond S. aureus . By 1...

Enzyme

...ome form of energy Autolysin : general term for enzymes that cause cells to die Beta-galactosidase: See lactase. Beta-lactamase : breaks down penicillin , rendering those bacteria that produce beta-lactamase resistant Catalase : converts hydrogen peroxide to oxygen and water Chitinase : break...

Fungus

...g among the amoebae . Miscellaneous The seeds of many orchids require a fungus to germinate . Fungi of the genus Penicillium produce penicillin , the first antibiotic known to modern science. Many bacteria have since become resistant to penicillin, but it is still used against Streptococ...

Lysozyme

...ation in the lysozyme gene, which leads to accumulated lysozyme in several tissues (). History Alexander Fleming (1881-1955), who discovered penicillin , described lysozyme in 1922 (Fleming A. On a remarkable bacteriolytic element found in tissues and secretions. Proc Roy Soc Ser B 1922;93:306-17)...

Antibiotic resistance

...tic pressure. It was the first bacterium in which penicillin resistance was found -- in 1947, just four years ... faecium is another superbug found in hospitals: penicillin resistance was seen in 1983, vancomycin resistance...as penicillin-resistant gonorrhea . Resistance to penicillin substitutes is also known beyond S. aureus . By 1...

Mycology

... is the study of fungi , their genetic and biochemical properties, their taxonomy , and their use to humans as a source for medicinals (see penicillin ) and food ( beer , wine , cheese , edible mushrooms ), as well as their dangers, such as poisoning or infection . Mycology is closely related t...
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