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Pazopanib in Medical News

NEW DATA FOR PAZOPANIB - GSK'S LATEST INVESTIGATIONAL ANTI-CANCER AGENT - SHOWS PROMISE ACROSS MULTIPLE CANCERS

Two Phase II studies demonstrated potential for pazopanib as a single agent treatment for early stage non-small cell lung cancer and advanced renal cell cancer: -- In patients with stage I-III non-small cell lung cancer, 86 percent of patients who received pazopanib monotherapy exper...

Drug That Targets Vasculature Growth Attacks Aggressive Thyroid Cancer, Mayo Clinic Researchers Report

...ifferentiated thyroid cancer treated with the drug pazopanib either stopped growing, or quickly shrank. T...d any effective therapies for such patients." pazopanib is an experimental agent that is also being studie...the growth and spread of tumors. The proteins that pazopanib targets include vascular endothelial growth factor...

Drug that targets vasculature growth attacks aggressive thyroid cancer

...ifferentiated thyroid cancer treated with the drug pazopanib either stopped growing, or quickly shrank. The...had any effective therapies for such patients." pazopanib is an experimental agent that is also being studie...the growth and spread of tumors. The proteins that pazopanib targets include vascular endothelial growth factor...

Research Findings on Nine GlaxoSmithKline Cancer Compounds to be Presented at ASCO 2009

...clude First Presentation of Phase III Progression Free Survival Results for pazopanib in Kidney Cancer LONDON and PHILADELPHIA, May 11 /PRNewswire/ -- G... ORAL PRESENTATION: "A randomized, double-blind Phase III study of pazopanib in treatment naive and cytokine-pretreated patients with advanced renal cel...

NYP/Weill Cornell physician-scientists present latest cancer findings at ASCO meeting

...oration with the MD Anderson Cancer Center. Preoperative treatment with pazopanib (GW786034), a multikinase angiogenesis inhibitor in early-stage non-small c...hly effective for the treatment of early-stage non-small cell lung cancer. pazopanib works by blocking the action of vascular endothelial growth factor receptor...

GlaxoSmithKline Presents Innovative Neuroscience Pipeline

... (US) Promacta (hep c) Wellbutrin XR (EU) Rotarix (US) Tykerb (H&N cancer) Tykerb + pazopanib (IBC) Before year-end, GSK will submit a regulatory filing to the FDA for Promacta, its first-in-class,...

Pazopanib Shows Positive in Advanced Renal Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

...announced results from ongoing Phase II studies of pazopanib in advanced or metastatic renal cell carcinoma (RC...Chicago. The results observed in these trials with pazopanib support further investigations. Pazopanib ...ntaining regimen). All patients received 800 mg of pazopanib taken orally, once-daily during a 12 week lead-in ...
Pazopanib in Medical Technology

GSK'S Pazopanib Shows Positive Results in Patients with Advanced Renal Cell Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

CHICAGO, June 04, 2007 /PRNewswire/ -- GlaxoSmithKline today announced results from ongoing Phase II studies of pazopanib in advanced or metastatic renal cell carcinoma (RCC), ovarian cancer and soft tissue sarcoma (STS). These trials were presented at the 43rd Annual Meeting of the American Socie...

US Oncology Affiliated Physicians Make a Strong Showing in ASCO Proceedings

...te-resistant prostate cancer (mCRPC)-preliminary results; Biomarker analysis and final results of a phase II renal cell carcinoma trial with pazopanib (GW786034), a multi-kinase angiogenesis inhibitor; A multicenter, prospective Phase II trial of sorafenib in patients (Pts) with metastatic ...

New Data Offers Insights Into the Potential Role for TYKERB(R) (Lapatinib) in Non-Cytotoxic Chemotherapy-Based Treatment Regimens

...w blood vessels (angiogenesis).(7) Lapatinib and pazopanib in HER2-positive advanced or metastatic breast can...Y, JUNE 1, 2008; 9:30 - 9:45 AM (CDT) TYKERB and pazopanib separately target the HER2 and VEGF pathways. This... 36.2 percent of patients treated with TYKERB plus pazopanib experienced disease progression versus 38.9 percen...

GlaxoSmithKline Reports Further Progress of Oncology Portfolio

...15 am - 9:30 am, E-Hall D1 Randomized study of pazopanib + lapatinib vs. lapatinib alone in patients with H...ults of a phase II renal cell carcinoma trial with pazopanib (GW786034), a multi-kinase angiogenesis inhibitorD...l Cell Lung Cancer Preoperative treatment with pazopanib (GW786034) a multikinase angiogenesis inhibitor in...

New Study Shows Doxorubicin Plus Paclitaxel Followed by Weekly Paclitaxel as Adjuvant Therapy for High Risk Breast Cancer Warranted in Place of Doxorubicin Plus Cyclophosphamide Followed by Paclitaxel

...ne in patients with myelodysplastic syndromes -- Thomas Hutson, D.O., PharmD, Associate Chair, GU Cancer, US Oncology Research: pazopanib (PAZ, GW786034) in pts w/ metastatic Renal Cell Carcinoma (RCC): Interim results of a PH II Randomized Discontinuation Trial (RDT) ...
Pazopanib in Biological Technology

33rd ESMO Congress in Stockholm, 12-16 September 2008

...xamine the benefits of customising lung cancer treatment based on mutations in the epidermal growth factor receptor (EGFR) gene. Phase II trial of pazopanib before surgery in early lung cancer (Embargoed until Monday, 15 September 2008, 10:45 CEST) Pazopanib, a new oral angiogenesis inhibitor, has demo...
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