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Pak1 in Medical News

Identified Protein To Inhibit Cell Migration

... CIB1 plays a prominent role in the activation of pak1 and potentially may be another important player in...regulation of this kinase. The other activators of pak1 include relatives of the notorious Ras family of t...ing the role that CIB1 plays in cell migration and pak1 activation, the authors used a new method known as...
Pak1 in Biological News

A step forward in virology

...ach one of the suspected proteins to examine their function,and narrowed the vast number of proteins down to 140 potential culprits. The enzyme kinase pak1 turned out to be an especially helpful citizen of Troy. Without PAK1, the pathogens trick did not work and the cell did not form any evaginations. ...

Fox Chase researchers discover a method for clamping down on a cancer-promoting enzyme

...now identified a molecule capable of shutting down pak1 before the enzyme becomes active. Previous studies have linked pak1 activity with breast cancer and have shown the enz...e molecule is capable of blocking signaling by the pak1 pathway. Previous work suggested that hyperact...

Protein found that slows hepatitis C growth in liver cells

...ition to presenting the researchers?discovery that pak1 controls the rate at which hepatitis C virus repli...er describes the biochemical pathways that lead to pak1 activation and the specific mechanisms by which pak1 interferes with the ability of hepatitis C to hija...

Pak1 expression increases tamoxifen resistance in breast cancer patients

...iversity in Malmö, Sweden, and colleagues examined pak1 expression in 403 premenopausal women with breast ...ent. The authors examined whether tumor levels of pak1 were associated with the women's chances of breast...xifen therapy. The authors found that increased pak1 expression was associated with increased resistanc...

UNC scientists discover new role for protein as fundamental inhibitor of cell movement

... "CIB1 plays a prominent role in the activation of pak1 and potentially may be another important player in...his kinase," she added. The other activators of pak1 include relatives of the notorious Ras family of t...s different from these GTPases. "CIB1 activates pak1 before Rac and Cdc42," said Dr. Leslie V. Parise, ...
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(Date:4/23/2014)... "simple and accessible detection methods that can rapidly ... of a single cell inside that population has ... Chang Lu. , In the Royal Society of ... announced that he and his coworkers have developed ... of a protein ( Chem. Sci. , 2014, ...
(Date:4/23/2014)... are often displayed in the popular Swedish children,s ... of high-sugar foods. A new study from the ... in children,s TV programmes as well as the ... and weight status. , Steingerdur Olafsdottir,s doctoral thesis ... popular Swedish children,s TV show Bolibompa. Healthy foods ...
(Date:4/23/2014)... led by a researcher from the Cancer Science Institute ... Singapore has identified the cancer specific stem cell which ... of developing new drugs for the treatment of this ... group, led by Dr Chan Shing Leng, Research Assistant ... that a cancer-specific variant of a cell surface protein, ...
(Date:4/23/2014)... in the journal Oncotarget , explored tumour ... or their own DNA signatures within the same ... design effective, targeted treatment strategies. , Firstly they ... and either the KRAS or BRAF mutation. Secondly, ... EGFR gene mutation have that specific mutation present ...
(Date:4/23/2014)... Alzheimer,s disease has been a rapidly evolving pursuit ... latest crook in the research road, scientists have ... proteins associated with the disease. The report, which ... , could have important implications for developing novel ... colleagues explain that for years, research has suggested ...
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(Date:4/23/2014)... ravens form different types of social relationships they ... form strict dominance relations. From a cognitive perspective, understanding ... in daily social life ("knowing who is nice or ... with each other sets the stage for "political" maneuvers ... study have been published in the scientific journal ...
(Date:4/23/2014)... Los Angeles, London (April 23, 2014). "I think one can ... energy pathwayas well as doing everything else that we canthen ... says Tom Wigley, one of the world,s foremost climate researchers, ... Scientists , published by SAGE. Refusing to take significant action ... will eventually be needed to address the problem, Wigley explains ...
(Date:4/22/2014)... team of Yale researchers will lead a five-year, $3 ... rain events is affecting the transport of dissolved organic ... they say could alter the chemical composition and water ... With funding from the National Science Foundation,s MacroSystems Biology ... across the watershed, which begins in Canada and runs ...
Breaking Biology News(10 mins):Ravens understand the relations among others 2Is nuclear power the only way to avoid geoengineering? 2Connecticut River watershed study will assess impacts of extreme rain events 2Connecticut River watershed study will assess impacts of extreme rain events 3
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