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Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

Deficiencies in the ability of cells to repair damaged DNA are associated with an increased risk of breast cancer, according to a new study in the January 19 issue of the Journal of the National Cancer Institute. is the system of defenses designed to protect the integrity of the genome. Studies have suggested that deficiency...

DNA Recombination and Repair—A New Twist to RecA Function

Molecular motors harness the energy of ATP (or GTP, a related energy currency) and transform it into mechanical force. Well-known examples of motors include myosin and dynein, proteins that use ATP to ferry intracellular cargo along fibers made of actin or tubulin proteins. The ATP-dependent assembly of actin or tubulin fibers itself can work as a motor: for instance, the march of white blood cel...

Heart repair gets new muscle

Some organs in the human body deal with injury better than others. A flesh wound or muscle tear might hurt, but, assuming you are otherwise healthy, both will heal. The prognosis for a heart attack, on the other hand, is not so clear-cut. It has long been thought that cardiac cells (cardiomyocytes) lack the capacity for self-renewal and repair, impeding the chances of a full recovery from...

Nano-bumps could help repair clogged blood vessels

Biomedical engineers at Purdue University have shown that "vascular stents" used to repair arteries might perform better if their surfaces contained "nano-bumps" that mimic tiny features found in living tissues. The researchers already have shown in a series of experiments that bone and cartilage cells in petri dishes attach better to materials that possess smaller surface bumps than are f...

New understanding of DNA repair may pave way to cancer treatments

A Burnham Institute study has found that a protein known for its role in gene regulation has another important function, that of initiating DNA repair. The study, published in the May 27th edition of Molecular Cell, points to new targets for treatment of cancer. Ze'ev Ronai, Ph.D., Director of the Institute's Signal Transduction Program, and his colleagues found that the protein ATF2 ("Ac...

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Anti-Human sVCAM-1 / CD106 ELI-PAIR Kit Antibody, Unconjugated from Cell Sciences

Description:Human sVCAM-1/CD106 ELI-PAIR Kit...
Company:Cell Sciences

DNA Repair Sampler Kit from BD Biosciences Pharmingen

Description:DNA Repair Sampler Kit 10g each...
Company:BD Biosciences Pharmingen

Anti-Human sIL-2R / CD25 ELI-PAIR Kit Antibody, Unconjugated from Cell Sciences

Description:Human sIL-2R/CD25 ELI-PAIR Kit...
Company:Cell Sciences

Pair at Biology Technology

RT-PCR Primer Sets for Human and Mouse Mismatch Repair Genes

Stratagene Cloning Systems from the cDNAsequences of mismatch repair genes. These genes code for specialized proteinsthat participate in correcting areas of base mispairing in DNA. We have...

Genome Wide Profiling of Paired Cancerous and Normal Breast Tissues and Rapid Interpretation of Gene Expression Data

Microarrays offer a powerful means of studying human gene activity and thereby providing insight into cellular, molecular, and biological changes. Applied Biosystems has developed the Expression Array System, a complete system for gene expression studies. It includes Human Genome Survey Microarrays (utilizing fully curated transcript data...

DNA Damage and Repair - Quantification of Sub-Cellular Events Using Automated Confocal Imaging

Oxidative stress, radiation and other external insults have been shown to damage DNA molecules in cells derived from organisms as diverse as bacteria, yeast, drosophila, rodents and man (Friedberg et al. 2005). The presence of DNA damage may lead to cell cycle checkpoint arrest to allow time for DNA repair...

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Wobble base pair

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Pair at Biology Dictionary

Wobble base pair

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Mismatch repair

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Mispairing

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DNA repair

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Base pair

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Pair at Medicine News

Pesticide impairs male reproductive function

According to the May issue of the journal Epidemiology, high levels of DDT found in some Mexican workers suggest that pesticide can impair male reproductive function. The human body metabolises DDT to DDE. An international team of researchers took blood samples from 24 men aged 16 to 28 who had not been exposed to DDT in their work. In these men the high DDE levels correlated to low leve...

Sense of smell impaired in alcoholics

A study published in the March issue of the journal Alcoholism: Clinical and Experimental Research reported that alcohol abuse can dampen the sense of smell. Researchers from the University Clinics of Innsbruck studied the sense of smell in 30 alcoholics and 30 healthy people who were matched for age, gender and smoking status. They used "Sniffin' Sticks", which are pen-like devices that...

Omega-3 fatty acids impair immunity

Taking large amounts of omega-3 fatty acids may be unwise for those with weakened immunity.Researchers at the University of Missouri, Columbia, have been studying omega-3s for many years now and know that one of their effects is to damp down inflammation. That's why fish oils - rich in omega-3s - often benefit those with arthritis, a painful inflammatory condition of the joints. Yet the i...

Clotting Protein plays a role in nerve repair

According to a new study, fibrin, a protein that helps form blood clots, may also be involved in regulating the repair of nerve damage. The discovery could lead to new strategies for repairing diseases of the nervous system, such as multiple sclerosis, although the research is still on the basic science level.// In multiple sclerosis, the slow destruction of myelin--the thin, protecti...

Heart may pull Cells from Body to Self-repair

According to researchers, after analysis of cells in men with transplanted hearts from female donors, the proof is the piling up that the heart may be able toregenerate itself at least somewhat by recruiting cells from elsewhere in the body.// Traditionally, it was thought that once cells were damaged or dead, they could not be replaced or repaired by the heart. By looking at the Y chr...

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Meniscal Repair/Suture Instruments

Description:For universal arthroscopic meniscal repair/suture. Uses double-armed, single-throw sutures....
Company:Innomed, Inc.

Zone Specific® II Meniscal Repair System

Description:A complete system of cannulas, needles and rasps specifically designed for inside-out meniscal repair procedures....
Company:Linvatec Corporation (now ConMed)

RapidLoc Meniscal Repair System

Description:The RapidLoc Meniscal Repair System is a second-generation "all-inside" system that offers several advantages over current systems including "inside-out" suture repair techniques and current "all-inside" rigid implants. This system is quick, simple, reproducible, reliable, and flexible in many ways, all while decreasing iatrogenic morbidity....
Company:DePuy Mitek

34670x Bagolini's Striated Lenses Pair

Description:Bagolini's striated lenses consists of 2 circular lenses in a metal frame with tabs for use by the examiner....
Company:Richmond Products, Inc.

A PAIR OF BANGOLINI LENSES No. 2

Description:A finely parallel striated (scratched) clear plastic membrane encapsulated between glass plates....
Company:Sussex Vision

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Pair at Medicine Technology

New Study Suggests no Significant Impairment in Middle-of-the-Night Balance, Mobility or Memory in Older Adults Using Ramelteon

SAN DIEGO, May 22, 2007 /PRNewswire/ -- A new study presentedtoday showed that ramelteon did not impair middle-of-the-nightbalance, mobility or memory performance in older adults withinsomnia, relative to placebo. This study also demonstrated, as inprevious studies, that patients treated with zolpidem did haveimpaired performances on these measures, as compared to placebo.The results of...

AGI Dermatics Data Shows the 8 Oxo-Guanine Repair Enzyme OGG1 Encapsulated in Liposomes, Reduces MMP-1 and TNF-alpha in UV Irradiated Skin Cells

Clinical Data Presented at the Society for InvestigativeDermatology FREEPORT, N.Y., May 16, 2007 /PRNewswire-FirstCall/ -- AGIDermatics today announced new clinical research that the8-oxo-guanine DNA glycosylase (OGG1) encapsulated in liposomesenhances DNA repair and reduces MMP-1 and TNF-alpha in UVirradiated skin cells. The data was presented at the 68th AnnualMeeting of the Society fo...

Sangamo BioSciences Announces Presentation of ZFP Therapeutic Data From Nerve Regeneration Program at American Society for Neural Therapy and Repair Meeting

Statistically Significant Improvements in Function in Spinal CordInjury Model With ZFP TF Treatment RICHMOND, Calif., May 03, 2007 /PRNewswire-FirstCall/ -- SangamoBioSciences, Inc. announced today the presentation of preclinicaldata from its ZFP Therapeutic(TM) program in nerve regeneration atthe Fourteenth Annual Conference of the American Society for NeuralTherapy and Repair. The data...

Data Show SuperGen's Multi-Targeted Tyrosine Kinase Inhibitor Suppresses Critical Double-Stranded DNA Repair Protein, Rad51

Other Presentations at AACR Highlight Progress in SuperGen'sOncology-Focused Pre-Clinical Pipeline LOS ANGELES, April 19, 2007 /PRNewswire-FirstCall/ -- SuperGenInc. today announced that MP470, its multi-targeted tyrosine kinaseinhibitor, suppresses the Rad51 protein, a critical component ofdouble- stranded DNA repair in cancer cells as part of a series ofpresentations at the 2007 America...

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Vision impairment

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Tendon repair

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Speech impairment

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Pectus excavatum repair

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Hernia repair

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