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PTC in Medical News

Quark Pharmaceuticals Announces the Presentation of Data Indicating Potential Utility of QPI-1002 in Chronic Kidney Disease at the RNA Interference Summit

... rats indicated excellent efficacy of the drug in reducing serum creatinine levels and ameliorating acute morphological damage to the kidney including ptc death. The data indicate that recurrent dosing of the drug concomitantly with monthly repetitive ischemic kidney insults minimizes the resulting kidn...

Smart Phones to be used by assisTek to Collect Patient-Reported Outcomes in a Large Multinational Clinical Trial

...with this capability. Participating in a clinical trial is a significant time commitment for patients, stated Dr. Temitayo Ajayi, Medical Director for ptc Therapeutics. "We believe it is beneficial to utilize state of the art technology, such as the assisTek Smart Phones to minimize the reporting b...

Also in the Jan. 27 JNCI

...three groups of people: 20 individuals with MNG that progressed to PTC; 284 ptc patients with no history of MNG; and 349 healthy individuals. Four of t...rkers to assess risk for MNG/PTC, through regular screening of relatives of ptc patients affected with MNG," the authors conclude. Contact: Winnie Lam, ...

Some Hiroshima Survivors at Thyroid Cancer Risk

...e may not have played a role in the development of ptc among patients who had the chromosomal rearrangeme... the disease. Hamatani noted that, among childhood ptc cases in particular, such chromosomal shifts are r...al changes, "needs to be confirmed with additional ptc patients in the future". In the meantime, Dr. A...

Defined Health Announces Final Speaker Roster and Agenda for Therapeutic Insight 2008

...Strategic Marketing * Professor Jutta Heim, PhD, Chief Scientific Officer, Basilea Pharmaceutica * Claudia Hirawat, SVP Corporate Development, ptc Therapeutics * Ginger S. Johnson, PhD, Vice President, Defined Health * Matthew W. Kalnik, PhD, VP, Business Development & Project Management, ...

Siemens Consortium to Construct Particle Therapy Center at the University Clinic of Schleswig-Holstein

...) As a competence center for tumor diseases, the ptc will be opening up new treatment possibilities for...facilities for applying particle therapy (PT), the ptc will also include a department for conventional ra...e started up at the beginning of 2012. "The Kiel ptc represents a milestone for medical engineering sol...

'Fluorescent' Retinal Cells Warn of Eye Disease

...o found that FA data more accurately described the degree of disease in each patient's eye as compared to the standard vision tests. The patients with ptc had FA values that averaged 60 percent greater in the eye that was more severely affected, the study said. By contrast, an age-matched control group h...

Drug fights cystic fibrosis

...ug status by the U.S. Food and Drug Administration for the treatment of Duchenne muscular dystrophy and CF, according to the biopharmaceutical company ptc Therapeutics, Inc. of South Plainfield, N.J. It works in an oral form. ...

Early detection critical in treating pediatric thyroid cancer

...thyroid hormones containing iodine. This type, the most common form of thyroid cancer in children, grows very slowly. The study also confirms that ptc is more prevalent in younger patients, compared with other age groups; these patients also had significantly larger tumors. However, the studys autho...

PTC Therapeutics Announces Additional $1.6 Million Grant from the Spinal Muscular Atrophy Foundation

...y SOUTH PLAINFIELD, N.J., Dec. 6 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC), a biopharmaceutical comp...l provide an additional $1.6 million in funding to ptc based upon completion of certain milestones. (Lo...smafoundation.org or call (646) 253-7100. About ptc Therapeutics, Inc. ...
PTC in Medical Technology

PTC Therapeutics Completes Enrollment of Pivotal Trial in Muscular Dystrophy

... SOUTH PLAINFIELD, N.J., Feb. 3 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC) today announced that it h...aken by clinical trial sites, advocacy groups, and ptc Therapeutics encouraged rapid identification of el...he first pivotal trial for ataluren. In addition, ptc is conducting an open-label, long-term safety stud...

PTC Announces Data Showing That PTC124 Causes Statistically Significant Improvements in Chloride Channel Function in Cystic Fibrosis Patients

...124 in CF," noted Dr. Campbell. "Our alliance with ptc and the development of PTC124 are key elements of ...xpedited development, evaluation, and marketing. ptc has an exclusive collaboration with Genzyme Corpor...C124 to include funding up to $25 million. About ptc Therapeutics, Inc. ...

PTC Therapeutics Announces Data Showing Six-Minute Walk Test Consistently Measures Ambulatory Function in Patients With Duchenne Muscular Dystrophy

... SOUTH PLAINFIELD, N.J., Sept. 30 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC) today announced promising...aid Langdon Miller, M.D., Chief Medical Officer of ptc Therapeutics, Inc. "We are hopeful that these data...me Corporation has an exclusive collaboration with ptc to develop and commercialize PTC124 outside the U....

PTC Therapeutics Announces $25 Million Award From Cystic Fibrosis Foundation Therapeutics for Development of PTC124

...cystic fibrosis (CF) caused by nonsense mutations. ptc will receive up to $25 million from CFFT in suppor... "We are pleased to expand our collaboration with ptc Therapeutics on the development of the therapy PTC...aging data from the Phase 2a studies indicate that ptc may become a very important drug for the treatment...

PTC Therapeutics Announces Data from Additional Clinical Studies of PTC124 in Cystic Fibrosis Confirming Activity

...nd PRAGUE, Czech Republic, June 12 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC) today announced promising...c disorders may provide clinical benefits. About ptc Therapeutics Inc. ptc is a biopharmaceutical company focused on the disc...

PTC Therapeutics Announces Data Supporting Cough Frequency as a New Outcome Measure in Evaluating Treatments for Cystic Fibrosis

...- SOUTH PLAINFIELD, N.J., May 21 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC) today announced new data ... dystrophy (DMD) and cystic fibrosis (CF). About ptc Therapeutics Inc. ptc is a biopharmaceutical company focused on the disc...

PTC Therapeutics Announces Initiation of Phase 2b Registration-Directed Clinical Trial of PTC124 in Duchenne/Becker Muscular Dystrophy

... SOUTH PLAINFIELD, N.J., April 23 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC), today announced the init...5 meters or approximately 80 yards in six minutes. ptc expects to enroll a total of 165 patients at appro... of the cases of CF are due to nonsense mutations. ptc believes that PTC124 is potentially applicable to ...

PTC Therapeutics Announces Publication of Preclinical Data in PNAS

...l SOUTH PLAINFIELD, N.J., Feb. 4 /PRNewswire/ -- ptc Therapeutics, Inc. today announced the publication...www.newscom.com/cgi-bin/prnh/20010919/PTCLOGO ) ptc has catalogued over 2,400 distinct genetic disorde...etween the University of Alabama at Birmingham and ptc Therapeutics. "These preclinical data further de...

PTC Therapeutics Presents Encouraging Phase 1 Results of its Novel VEGF Inhibitor, PTC299, at 30th Annual San Antonio Breast Cancer Symposium

...ented Stuart W. Peltz, Ph.D., President and CEO of ptc Therapeutics, Inc. "PTC299 is an example of the ut...lar endothelial growth factor, or VEGF, in tumors. ptc discovered PTC299 through PTC's proprietary GEMS (...o official endorsement should be inferred. About ptc Therapeutics, Inc. ...

PTC Therapeutics Announces Additional Results from Phase 2 Study of PTC124 in Duchenne Muscular Dystrophy

... SOUTH PLAINFIELD, N.J., Oct. 18 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC), a biopharmaceutical comp...duce ribosomal read through of normal stop codons. ptc is currently conducting Phase 2 clinical trials of...of the cases of DMD are due to nonsense mutations. ptc believes that PTC124 is potentially applicable to ...
PTC in Biological News

PTC124 shows activity in cystic fibrosis; Phase 2 proof-of-concept data published in Lancet

...ity Hospital in Jerusalem, Israel and sponsored by ptc Therapeutics (PTC). Patients with CF lack adequ...se of CF. We are continuing to work together with ptc and the broader CF medical community to support th...z, Ph.D., President and Chief Executive Officer of ptc Therapeutics. "Based on these results, we intend ...

'Fluorescent' cells give early warning for eye disease

...r visible signs appear. The women in the study were newly diagnosed with ptc and had not yet received treatment. According to standard tests they had g...r the six women and the age-matched control group. All of the patients with ptc had higher FA values in the eye that was more severely affected. In fact, F...

Presence of gene mutation helps guide thyroid cancer treatment

...tute. Most patients diagnosed with thyroid cancer have small, localized ptc but may receive aggressive treatment because their risk of recurrence and d...n 24.1 percent of patients with follicular variant PTC. In conventional ptc and follicular variant PTC, the mutation was significantly associated with ...

Research updates 65-year-old genetic discovery

...ity to a bitter compound known as phenylthiocarbamide (PTC) was mapped in human genes. "That gene was found to be controlling whether you can taste ptc or not," says Stone, an associate professor in ASU's School of Human Evolution and Social Change in the College of Liberal Arts and Sciences. "We d...

Role of microRNA identified in thyroid cancer

...eed cause some people to be more likely to develop ptc than others, the mutations may not occur often eno...ble. They hypothesized that any predisposition to ptc might be more reasonably linked to a more subtle, ...f malignant tissue from 15 patients diagnosed with ptc and compared them with normal appearing tissue adj...
PTC in Biological Technology

Genzyme Corporation and PTC Therapeutics Announce Collaboration on Small Molecule for Genetic Diseases

- Potential New Treatment Paradigm, PTC124 - CAMBRIDGE, Mass. and SOUTH PLAINFIELD, N.J., July 17 /PRNewswire- FirstCall/ -- Genzyme Corporation (Nasdaq: GENZ ) and PTC Therapeutics, Inc. (PTC) today announced an exclusive global collaboration to develop and commercialize PTC124...

PTC Therapeutics Initiates Phase 2 Clinical Trial of PTC299 in Patients with Neurofibromatosis Type 2

... SOUTH PLAINFIELD, N.J., July 27 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC) today announced the initi...aid Langdon Miller, M.D., Chief Medical Officer of ptc Therapeutics. "We are hopeful that the novel mech...matosis Research Program. About PTC299 ptc 299 is a novel, orally administered small-molecule...

PTC Therapeutics Receives $2.6 Million in Government Grants

... SOUTH PLAINFIELD, N.J., June 15 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC) today announced the recei... Office of Orphan Products Development has awarded ptc a four-year, $1.6 million grant towards its ongoin...z, Ph.D., president and Chief Executive Officer of ptc Therapeutics. "Obtaining peer-reviewed grant awar...

PTC Therapeutics Appoints Clare Kennedy as Vice President of Commercial Operations

... SOUTH PLAINFIELD, N.J., June 1 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC) today announced that Clar...s. Kennedy is also a Registered Nurse. About ptc Therapeutics, Inc. ptc is a biopharmaceutical company focused on the disc...

Follica Appoints Drug Development and Dermatology Veteran, William D. Ju, as Chief Executive Officer

...g dermatology. Prior to joining Follica, he was chief operating officer at ptc Therapeutics, a privately-held biopharmaceutical company. In that position...ge commercialization company. Since 2003 while he was there, Dr. Ju helped ptc triple in size, complete a $50 million Series E round, and enter into a par...

PTC Therapeutics and Spinal Muscular Atrophy Foundation Announce $8.5 Million Small Molecule Development Collaboration

...INFIELD, N.J. and NEW YORK, May 12 /PRNewswire/ -- ptc Therapeutics, Inc. (PTC) and the Spinal Muscular A...s." "The extension of our collaboration with ptc reflects substantial progress to date," said Meg W...of death among infants and toddlers." About ptc Therapeutics, Inc. ...

Stephen H. Friend, MD, PhD to Keynote at Defined Health's 9th Annual Therapeutic Insight Conference

...dustry issues and trends in oncology, pain, COPD, biologics and frailty in aging: John Babiak, PhD, SVP, Discovery Technologies, ptc Therapeutics, Inc. Karen Bernstein , PhD , Chairman & Editor-in-Chief, BioCentury Maria Paola Chiesi, PhD , Corporate Ma...

PTC124 Shows Promising Activity in Cystic Fibrosis; Phase 2 Proof-of-Concept Data Published in the Lancet

...ity Hospital in Jerusalem, Israel and sponsored by ptc Therapeutics (PTC). (Logo: http://www.newscom.c...rse of CF. We are continuing to work together with ptc and the broader CF medical community to support th...z, Ph.D., President and Chief Executive Officer of ptc Therapeutics. "Based on these results, we intend t...

Human Genome Sciences Appoints David P. Southwell to its Board of Directors

...Dartmouth College. Mr. Southwell serves as Chairman of the Board of Directors for BioSphere Medical, Inc. and is a member of the Board of Directors of ptc Therapeutics, Inc. He is also Chairman of the Tuck School of Business MBA Advisory Board and a member of the Tuck School of Business "Investing for Ex...

Genzyme Reports Strong Second-Quarter Growth

...ndard of care for severely ill patients whose needs cannot be addressed by current therapies. -- Genzyme also formed a collaboration this month with ptc Therapeutics to develop and commercialize PTC124, a novel oral therapy under development initially for Duchenne muscular dystrophy and cystic fibrosis...
PTC in Biological Dictionary

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...omoter site ) Also found in: Medical, ... Welcome To Promoter Heaven ptc Site ! Paid To Click Ads worth $1 to $5 ... Copyright © 2008 Promoter Heaven ptc Site . Site By Premiere-PTC-Network ... Platinum KeyWords will help y...

Frameshift Mutation

...clusively in MSI-H colorectal cancer cell ... The frameshift mutations observed in the affected genes are expected to generate ... Although ptc formation in frameshift mutation -derived mRNAs and their subsequent ... A site dedicated to ... Typically, a frameshift mutation in a tra...
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