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PPI in Medical News

Takeda's investigational PPI TAK-390MR demonstrated higher healing rates compared to lansoprazole

Combined results from two Phase 3 studies presented at the American College of Gastroenterology Annual Scientific Meeting (ACG) in Orlando, Fla., demonstrated that TAK-390MR resulted in higher healing rates than lansoprazole among patients with more severe grades of erosive esophagitis (EE). TAK-3...

Heartburn Drugs May Contribute to the Problem

... four weeks of placebo. Forty-four percent of individuals receiving the ppi reported acid-related symptoms after stopping the medication, compared wit...e sure that the conclusion can be carried over to patients who have started ppi therapy because of dyspeptic symptoms. A previous systematic review of rebo...

P&G Response to FDA Approval of Prevacid OTC(R) 24HR

...unter heartburn remedy in the U.S.," said Tim Brown - General Manager, P&G Personal Health Care North America. "Procter & Gamble built the OTC ppi market and since 2003, millions of consumers have made Prilosec OTC their frequent heartburn remedy of choice. We don't expect that to change given ou...

Video: Novartis Receives Approval From FDA to Market Prevacid(R) 24HR as First and Only OTC Proton Pump Inhibitor in Original Prescription Formulation

...e.com/mnr/prevacid/38457/ Once-daily Prevacid 24HR is the first OTC ppi approved in its original prescription formulation. It is the only ppi containing the active ingredient lansoprazole to be approved for OTC treatm...

Plavix, Heartburn Drugs May Be Risky Combination

...ns (SCAI), is that the combination of Plavix and a ppi increases the user's risk of heart attack, stroke ...x, Nexium, Prilosec and Prevacid, but not to newer ppi drugs such as Aciphex and Kapidex, it said. The...was 51 percent higher in those taking Plavix and a ppi than in those taking Plavix alone, Stanek said. ...

SCAI Statement on 'A National Study of the Effect of Individual Proton Pump Inhibitors on Cardiovascular Outcomes in Patients Treated with Clopidogrel Following Coronary Stenting: The Clopidogrel Medco Outcomes Study'

...on pump inhibitors (PPIs). In the study, patients taking clopidogrel and a ppi experienced a: 50% increase in the combined risk of hos... a PPI. The current study examined outcomes of patients taking common ppi medications including pantoprazole (Protonix), esomeprazole (Nexium), omepr...

Acid Reducers May Not Help All With Asthma

...pressing medications known as proton pump inhibitors (PPI). But a study in the April 9 issue of the New England Journal of Medicine repots that a ppi probably isn't going to help lessen wheezing in people with silent GERD. "Patients with asthma that is not adequately controlled with the usual ast...

Heartburn Sufferers Find Lasting Relief With TUMS(R) Dual Action

...mp inhibitors (PPIs). Despite high compliance with PPIs, the group of prescription heartburn drugs that reduce stomach acid production, 46% or more of ppi users experience breakthrough heartburn, or episodes of heartburn between doses, often at night. TUMS Dual Action can safely be taken to provide relie...

Blood Thinner, Heartburn Drugs May Be Risky After Heart Attack

...ix and also a lot of patients are being prescribed ppi medication just prophylactically to prevent a stom...oth clinicians and patients should look at why the ppi is being prescribed. It shouldn't be prescribed pr... because there might be an interaction between the ppi and Plavix," he said. A proton pump inhibitor s...

What is the most effective therapy for low-dose aspirin induced peptic ulcer?

... 1.9 and 1.9 2.3 in 8 and 16 patients receiving prevention therapy with a ppi and an H2RA, respectively. Both scores were significantly smaller than the ...r drugs (4.3 1.6). In the prospective study, 18 and 13 patients received a ppi and an H2RA, respectively. Endoscopic examinations revealed that the tissue...

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PPI in Medical Technology

Takeda's Investigational PPI TAK-390MR Demonstrated Higher Healing Rates Compared to Lansoprazole as the Severity of Erosive Esophagitis Grade Increased, a New Integrated Analysis Showed

TAK-390MR Data Presented at the American College of Gastroenterology Annual Meeting ORLANDO, Fla., Oct. 6 /PRNewswire/ -- Combined results from two Phase 3 studies presented at the American College of Gastroenterology Annual Scientific Meeting (ACG) in Orlando, Fla...

Research: Popular Diabetes Medications Associated with Increase in Bone Fractures

...mportant due to the increased risk of cardiovascular disease in people with diabetes. According to researchers, patients with diabetes who took a ppi and clopidogrel together experienced a 44 percent higher relative risk for a cardiovascular event than patients taking clopidogrel alone. Of those wh...

New Studies Show Popular Heartburn Medications Moderate the Effect of Taking Widely Prescribed Heart Drug

..., which together accounted for about 96 percent of ppi use in the study. Other PPI's, including rabeprazo...part of this research effort found that the use of ppi therapy in conjunction with clopidogrel increases ...38 percent; the annual cost for patients on both a ppi and clopidogrel was $6,061 as compared to $4,400 f...

American Lung Association Study to be Published in the 'New England Journal of Medicine' Finds Prescription Heartburn Medication Does Not Control Asthma Symptoms as Previously Thought

...quality of life. GER documented by pH probe studies in 40% of participants with absent or minimal symptoms did not identify a subgroup benefiting from ppi treatment. Serious adverse events were fewer with esomeprazole than placebo (11 vs. 17). Conclusion: Despite a high prevalence of asymptomatic ...

TAP Pharmaceutical Products Inc. Announces Phase 3 TAK-390MR Data Demonstrating Higher Overall Healing Versus Lansoprazole in Patients with Erosive Esophagitis

...W) annual meeting in San Diego. "The innovative dual delayed release technology delivers TAK-390MR in two separate releases, which is a first in the ppi class and makes TAK-390MR a very interesting potential future treatment option," said Dr. David Peura, professor of medicine, University of Virginia H...

Additional Data From Satraplatin SPARC Phase 3 Trial Presented at European Association of Urology Congress

...sent pain intensity (PPI) and analgesic score. The ppi score was defined according to the McGill-Melzack ...equal to 2 point reduction in the patients' weekly ppi score from baseline and maintenance of the two poi...were evaluable for pain response if their baseline ppi score was greater than or equal to one and had com...

Liponex Inc. Reports Further Analysis of CRD5 Phase I/II Clinical Trial Data

...n of gastric acid and reduce the acidity of the stomach. Patients that took ppi regularly during the trial showed an increased CRD5 efficacy with a mean HD...e, President and CEO of Liponex. "These results, particularly the impact of ppi on CRD5 efficacy, support our ongoing preclinical studies and guide our str...

New England Journal of Medicine Publishes New Data on Gardasil, Merck's Cervical Cancer Vaccine

...-- Month 36 196 59.7 (48.5, 73.5) 193 4.8 (4.4, 5.2) ---------------------------------------------------------------------- * The ppi population consisted of individuals who received all 3 vaccinations within pre-defined day ranges, did not have major deviations from the study pr...

Data Published in The Lancet Show Gardasil was 100 Percent Effective in Preventing High-Grade Vulvar and Vaginal Lesions Caused by HPV Types 16 and 18

...-- Month 36 196 59.7 (48.5, 73.5) 193 4.8 (4.4, 5.2) ---------------------------------------------------------------------- * The ppi population consisted of individuals who received all 3 vaccinations within pre-defined day ranges, did not have major deviations from the study pr...

Additional Efficacy Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at Annual Meeting of American Urological Association

...sent pain intensity (PPI) and analgesic score. The ppi score was defined according to the McGill-Melzack ...equal to 2 point reduction in the patients' weekly ppi score from baseline and maintenance of the two poi...were evaluable for pain response if their baseline ppi score was greater than or equal to one and had com...
PPI in Biological Technology

Canadian Government Announces Funding for Leading Biotechnology Firm's Project

...DTC) are pleased to announce that a project led by ppi will be receiving up to $5,565,063 in funding from...- for conversion into renewable sources of energy. ppi has discovered a family of technologies called Enh... biofuel conversion technologies will be driven by ppi trait improvements have the potential to offer the...

FDA Approves KAPIDEX(TM) (Dexlansoprazole) delayed release capsules for the Treatment of GERD

..." said Alan MacKenzie, president and CEO, Takeda Pharmaceuticals North America. "KAPIDEX is a new, innovative treatment option in the well-established ppi market." PPIs work by reducing acid production by turning off many of the acid pumps in the stomach. KAPIDEX contains two types of enteric-coated...

Leading Canadian Scientist to speak at UN Climate Change Conference

... yield losses normally attributed to adverse climactic conditions. As well, ppi is developing optimized feedstock technologies that directly increase non-f... convertibility into cellulosic ethanol and renewable bioproducts. ppi has licensed its breakthrough Yield Protection Technology(R) to some of the...

Performance Plants Establishes U.S. Biofuels Facility

...artered in Kingston, Ontario, Canada, it has Research and Development facilities in Kingston, Ontario, Saskatoon, Saskatchewan and Waterloo, New York. ppi has developed a suite of weatherproofing traits including its breakthrough Yield Protection Technology(R) (YPT(R)) which has been licensed to companie...

Ranbaxy and AstraZeneca Reach Agreement in Esomeprazole Patent Litigation

...rom the impact of GERD amongst patients. Felodipine is a calcium antagonist for the treatment of hypertension and angina. Omeprazole was the first ppi and is used for the short-term treatment of acid-related diseases. Ranbaxy Pharmaceuticals Inc. (RPI) based in Jacksonville, Florida, is a wholly ow...

Bluestar Silicones Introduces Three New Soft and Durable Liquid Silicone Rubber Products

...althcare Market Manager. "Now with these new products, molders can achieve both softness and strong physicals, with tear and elongation as high as 170 ppi and 1090%, respectively. This opens the door to a much broader range of applications in the healthcare arena." The superior tear strength and easy p...

Schering-Plough Announces Filing of U.S. Application for OTC ZEGERID(R)

...ERID (omeprazole/sodium bicarbonate) prescription products in both 20 mg and 40 mg dosage strengths of omeprazole for the U.S. prescription market for ppi products. Product Description ZEGERID(R) (omeprazole/sodium bicarbonate) contains omeprazole, a proton pump inhibitor (PPI), and sodium bicarbonat...

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