InteKrin Therapeutics Announces INT131 Phase 2a Results at the 2009 American Diabetes Association Annual Meeting
...rtive of INT131 acting as a selective modulator of ppargamma
in T2DM patients," remarked Dr Alex DePaoli, Chief...-TZD insulin sensitizer and selective modulator of ppargamma
(SPPARM). INT131 belongs to a unique, non-TZD che...lidated and robust insulin sensitizing efficacy of ppargamma
while minimizing the typical side effects seen wit...
Target for obesity treatment
...tep process: generalized cells first turn into transitional fat cells, then ppargamma
helps turn those transitional cells into fat cells. The ppargamma
gene actually produces two forms of its protein, called PPARgamma1 and PPAR...
PPARGamma in Biological News
Gut research yields new anti-cancer approach
...esearch. Furthermore, the new studies suggest that ppargamma
inhibitors act through some of the same mechanisms...
While studying whether compounds known to affect ppargamma
could play a role in inflammatory bowel diseases, ... Medical Center found that medium-to-high doses of ppargamma
inhibitor killed colorectal cancer cell lines. Des...
PPARGamma in Biological Products