Study further expands understanding of leptin's role in brain neurocircuitry
...n leptin sensitivity is restored to a tiny area of pomc
neurons in the brain's hypothalamus, a group of mi...jorbaek. "We hypothesized that, in both cases, the pomc
neurons were involved."
To test their hypothesi...electively re-express leptin receptors only in the pomc
neurons. When leptin receptor activity was restore...
Serotonin the Answer for Anti-Obesity Treatment
...-phen and other serotonin-inciting drugs on both normal and genetically engineered lean and obese mice. They found that serotonin's dual regulation of pomc
and AgRP neurons is necessary to promote weight loss. ‘The finding increases the understanding of the molecular circuitry that controls body weight in...
POMC in Biological News
Killer carbs -- Monash scientist finds the key to overeating as we age
...in that we are hungry. When we are full, a set of neurons known as POMC's kick in.
"However, free radicals created naturally in the body attack the pomc
neurons. This process causes the neurons to degenerate overtime, affecting our judgement as to when our hunger is satisfied," Dr Andrews said.
'Guardian of the genome' protein found to underlie skin tanning
... is split apart. They also knew that the amount of pomc
within cells rises sharply when they're exposed to UV rays. But they didn't know what caused the pomc
One possibility was p53. When Fi...is colleagues examined the section of the gene for pomc
that promotes production of the protein, they foun...
An essential regulator of body weight revealed
... the arcuate nucleus. The first of these, known as pomc
(pro-opiomelanocortin) neurons, send signals to ot...the brain to reduce appetite. Mice with defects in pomc
neurons eat excessively and become obese.
The ...ators of feeding behavior, acting in opposition to pomc
neurons to stimulate appetite. But genetic experim...
POMC in Biological Products
Pro-OpioMelanoCortin (POMC) ELISA Kit from IDS Ltd
Description:...ertebrates studied, including those "living fossils", the lungfish. The IDS pomc
ELISA measures "ACTH precursors" (i.e. measures both pomc
and pro-ACTH equally) in plasma samples, and provides an invaluable tool to...
POMC in Biological Dictionary
...rst gene. ... A number of genes are now known to be polycistronic , that is, they produce more than one protein. ... Polycistronic genes such as pomc
make the genome very ... ...