PLoS

Stemedica Medical Team Cautions Patients About Stem Cell Therapy & Comments on PLoS Medicine Article

Stemedica provides its observations and comments to the media regarding the PLoS Medicine article published online February 17, 2009. The PLoS Medicine article describes a patient who developed "brain tumors" (glioneuronal neoplasms) after undergoing repeated transplants of "fetal...

Carnegie Mellon develops innovative method to detect genetic causes of complex diseases

...ziness and tightness of the chest and others to lung physiology. Some of these traits are highly correlated with each other, Xing and Kim noted in the plos Genetics article, which suggests a common genetic basis. Their technique takes advantage of these tightly correlated traits by analyzing them jointly....

Key Factors Define 'Prolonged Grief'

...gnostic criteria. In the study appearing online Aug. 3 in the journal plos Medicine , researchers from Dana-Farber Cancer Institute in Boston develope... -- Kevin McKeever SOURCE: plos Medicine , news release, Aug. 3, 2009 ...

Genes key to staph disease severity, drug resistance found hitchhiking together

...found the gene for the toxin traveling with a genetic component of Staphylococcus that controls resistance to antibiotics. The study, now online in plos Pathogens , shows for the first time that genetic factors that affect Staphylococcus virulence and drug resistance can be transferred from one strai...

Gene Found for Age-Related Cataract

... can clump together and cause the eye lens to become cloudy, resulting in obscured vision, according to the study in the July 31 issue of the journal plos Genetics . The international group of researchers, including a team from Case Western Reserve University in Cleveland, have identified several muta...

Neuronal survival and axonal regrowth obtained in vitro

...MC have just developed a strategy that could promote neuronal regeneration after injury. The in vitro studies have just been published in the journal plos ONE . Repair of the central nervous system and restoration of voluntary motor activity through axonal re-growth has long been considered impossible ...

PLoS in Medical Technology

Technique for Rapidly Reprogramming Adult Cells Into Stem Cells Published in PLoS Biology

- Technology In-Licensed by Stem Cell Sciences From University of Cambridge - ("Stem Cell Sciences", "SCS", "the Company") CAMBRIDGE, England, Oct. 24 /PRNewswire/ -- Stem Cell Sciences plc (AIM: STEM, ASX: STC), a company focused on the commercialisation of stem cells and stem cell ...

More Gene Mutations Linked to Autism Risk

...ere transmitted in some, but not all, of the affected individuals in families. The findings were published in the June 26 edition of the journal plos Genetics . By further refining the genetic landscape of ASDs, the current study expands the findings of two large autism gene studies published i...

In Rare Disorder, a Familiar Protein Disrupts Gene Function

...he National University of Colombia, in Bogota, Colombia. Liu et al, "Transcriptional dysregulation in NIPBL and cohesin mutant human cells," plos Biology , published online, May 26, 2009. About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1...

Taking Folic Acid for a Year Before Pregnancy May Reduce Risk of Preterm Birth

...ar before they become pregnant may cut their risk of having a premature baby by half, according to research published this week in the online journal, plos Medicine. The study links pre-conceptional folate supplementation of at least one year to reduced early premature delivery rates of 50 to 70 perc...

Scientists Discover a Role for the Growth Factor TGF-beta in Maintaining Health of Retinal Blood Vessels

...ause retinal dysfunction. These findings, published in the April 2 issue of plos ONE, may have an important impact on the prevention and treatment of diseas... vessel structure and function. According to Walshe, the goal of the plos ONE study was to determine if TGF-beta plays a role in keeping blood vessel...

New Study Shows Cloning from Dried Cells Now Possible

...unced that cloning with freeze-dried cells is possible for the first time, according to new study findings in the August issue of the research journal plos One. The company's patented IMT freeze-drying technology was used in the study. Cloning starts when an egg without genetic material is injected with...

PLoS in Medical Definition

Social medicine

... Social Medicine Evolve, and Where Is It Heading?" plos Med 3(10): e399. DOI: 10.1371/journal.pmed.0030399...riographical essay. J Hist Sociol 1: 90–106. The plos Medicine Editors, Stonington S, Holmes SM (2006) Social medicine in the twenty-first century. plos Med 3(10): e445. DOI: 10.1371/journal.pmed.0030445...

PLoS in Medical Dictionary

Gene

...n receptor-related protein 4) mouse homolog has similarity to the low density lipoprotein receptor family, however, it does not bind very ... plos Genetics is an open-access ... Similarly, in human muscle, a gene expression profile of aging was found to ... changes in gene expression levels...

Amnion

... Amnion :: The pregnancy and long-term neurodevelopmental ... Mesh-terms: Amnion ; Animals; Basement Membrane; Cells, Cultured; Collagen : ... plos ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. ... Rupture of amnion is thought to be associated with a ...

PLoS in Biological News

The first impact factor for PLoS Biology ?13.9

The open-access journal PLoS Biology has been assessed by Thomson ISI to have an impact factor of 13.9*, which places PLoS Biology among the most highly cited journals in the life sciences. This is an outstanding statistic for a journal less than two years old, from a new publisher promoting a new ...

Rodent size linked to human population and climate change

...ty and climate change. The finding is reported by Oliver Pergams, UIC research assistant professor of biological sciences, in the July 31 issue of plos One . Pergams said that such size-and-shape changes in mammals, occurring around the world in less than a century, are quite substantial. He had...

E-Noses: Testing their mettle against fly noses

...hat are independent of each other and human engineers haven't yet worked out how to do this. "These results, published today in the science journal plos ONE , will help in the design of better e-noses and help us understand better how biological systems work," Dr Trowell said. Bio-benchmarking approa...

1 in 6 health workers won't report in flu pandemic -- study by Ben-Gurion U. researchers

...ers will not report for work in a pandemic flu emergency, regardless of the severity. The study,just published in the peer-reviewed online journal plos ONE , as conducted among 1,835 public health workers in Minnesota, Ohio and West Virginia from November 2006 to December 2007. "We found belief ...

Vaccine blocks malaria transmission in lab experiments

...ife cycle and necessary for continued transmission of malaria from mosquitoes to humans. The study is published in the July 22 edition of the journal plos ONE . "Development of a successful transmission-blocking vaccine is an essential step in efforts to control the global spread of malaria. In our s...

Warming climate threatens California fruit and nut production

...Girvetz, who is now a postdoctoral research associate at the University of Washington, Seattle. Their study will appear July 22 in the online journal plos ONE . The study is the first to map winter chill projections for all of California, which is home to nearly 3 million acres of fruit and nut trees ...

PLoS in Biological Technology

Practice makes perfect -- motor memory possible for neuroprosthetic control

...ctice must eventually modify the performer's nervous system so that stable motor memories of the physical actions are formed. In this week's issue of plos Biology , new research reveals that macaque monkeys can achieve a kind of consolidation of motor memory when using a neuroprosthetic device to complet...

UCSF researchers help crack parasite genome, identify drug leads

...line at www.nature.com . The second paper, published July 14, 2009 in " plos Neglected Tropical Diseases " and online at www.plosntds.org , documents t...ment of Pathology, who co-authored both papers and was senior author on the plos paper on the compound discovery work. The current drug also is not ideal as...

Novel method predicts impact of a covert anthrax release

...the Health Protection Agency's Microbial Risk Assessment group. The method, described in an article published April 10 in the open-access journal plos Computational Biology , predicts where the most critically affected areas will be following the release of this highly pathogenic agent, which may ena...

febit First to Offer Newly Published Mouse Genome on a Chip for DNA/RNA Detection and Enrichment

...ll-established model for the study of human disease and mammalian development. At the end of May 2009, D.M. Church et al. published in the journal plos Biology a complete, high-quality genome assembly that contains over 139 Mb more of novel sequence compared to previously available mouse genome drafts...

Preclinical Proof-of-Concept Studies Published for Novavax Seasonal Influenza Virus-Like-Particle Vaccine

...nducted by scientists from the University of Pittsburgh , Center for Vaccine Research and Novavax, was published in the June 24, 2009 online issue of plos ONE. The vaccine contains three VLPs mixed together in a single formulation; each made up of the hemagglutinin (HA), neuraminidase (NA) and matrix 1 ...

Novel method predicts impact of a covert anthrax release

...the Health Protection Agency's Microbial Risk Assessment group. The method, described in an article published April 10 in the open-access journal plos Computational Biology , predicts where the most critically affected areas will be following the release of this highly pathogenic agent, which may ena...

PLoS in Biological Definition

Antibody

...hysiology (4 th ed.). Brooks/Cole. ISBN 0534421741 External links Lymphomation: Immunoglobulins How Lymphocytes Produce Antibody plos primer: V(D)J Recombination and the Evolution of the Adaptive Immune System ...

Digital organism

...a home page Physis home page Tierra home page Darwinbots home page Further reading O'Neill, B. (2003). Digital Evolution. plos Biology 1 , 011-014. Wilke, C.O. & Adami, C. (2002). The biology of digital organisms. Trends in Ecology and Evolution 17 , 528-532. ...

Endosymbiont

...inium. Andrew C. Baker, Annual Review of Ecology, Evolution, and Systematics 2003 34, 661-689 Obligate bacterial endosymbionts in insects: plos Biology Primer- Endosymbiosis: lessons in conflict resolution http://www.plosbiology.org/plosonline/?request=get-document&doi=10.1371/journal.pbi...

Endosymbiont

...inium. Andrew C. Baker, Annual Review of Ecology, Evolution, and Systematics 2003 34, 661-689 Obligate bacterial endosymbionts in insects: plos Biology Primer- Endosymbiosis: lessons in conflict resolution http://www.plosbiology.org/plosonline/?request=get-document&doi=10.1371/journal.pbi...

Genomics

...motif gene therapy genetic engineering structural genomics List of omics topics in biology Sources and external links plos Primer: Comparative Genomics "The Human Genome Issue" Nature , February 15 , 2001 , no. 6822 Genomics Online Database - http://wit.integrat...

Proteasome

...latory particle is attached to each end of the 20S core particle via its base. Some of the subunits in the base are ATPases . External links plos Primer: The Proteasome and the Delicate Balance between Destruction and Rescue The Yeast 26S Proteasome with list of subunits and pictures Pic...

PLoS in Biological Dictionary

Untranslated RNA

...inding proteins with 5′- or 3′- untranslated regions (UTRs) of mRNA. ... Tumor suppression by RNA from the 3′ untranslated region of α ... plos Medicine is an open-access, peer-reviewed medical journal that publishes outstanding human studies that ... the 5′- untranslated RNA of the ... ...

Transposon mapping

...on which spans nucleotides 15215 to 15681 on the transposon map . ... an intact chromosome-borne transposon Tn916 delta E. Cloned segments ... plos Genetics ... global mapping approach for identifying transposon locations ... apply this method to mapping bacterial transposon insertion si...

Synapomorphy

...e establishment of homology qua synapomorphy ... qua synapomorphy , i.e. as similarity due to common ancestry, on the basis of available ... plos ONE: an inclusive, peer-reviewed, open-access resource from the ... Alternative 1: The stem-cell system is a synapomorphy of Acoela and Rhabditophor...

Suberin

...rin . suberin synonyms. suberin usage examples and suberin quotes. ... suberin definition. su·berin (so̵̅o̅′bər in, so̵̅o̅ ber′in) noun ... plos Genetics is an open-access ... Furthermore, these changes in suberin and water transport were associated with ... Higher suberin content within ma...

Sub-cloning

...s .. Software .. FTP. sub - cloning and protein purification ... sub - cloning and protein purification in E. coli. 1. Sub - cloning . ... plos ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC ... Sub - cloning vector-derived fragments requires the donor fragment to be ...

Satellite RNA

... II dependant transcripts of abundant centromeric ... This alpha satellite RNA is required for the association of kinetochore proteins ... plos ONE: an inclusive, peer-reviewed, open-access resource from the ... This alpha satellite RNA is required for the association of kinetochore pro...