New approach to cancer: Find most tightly controlled genes
...s a "poised gene cassette" or PGC. "We view the pgc genes as an exciting new class of genes, in which ...fect on the tumor," Tan said. "This would make the pgc genes attractive targets." For example, a treatment targeting a pgc gene might only need to inhibit protein activity b...Why your fertility cells must have 'radio silence'
... to produce germ cells. Initially, Dr. Lasko said, they discovered that the pgc gene produced an RNA, but they did not believe it produced any proteins. Using current technology, Dr. Nakamura discovered that pgc does indeed produce a protein which regulates Transcription Elongation Fact...Poor Glycaemic Control In Hispanics With Diabetes Causes Severe Depression
... Hispanics with diabetes. "We found a steady increase in the probability of pgc with advancing categories of depression severity," according to Raz Gross, ...y true among patients with moderate-severe depression, where likelihood for pgc was more than three-fold higher compared to patients without depression," s...