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PDZ in Medical News

A Detail Analysis of Head and Neck Cancer

...ular interactions and can be used in the potential treatment that could prevent both pathways from being initiated. Inside the LARG segment there is a pdz domain which when introduced into the tumor cell, it binds up all available CD44 and EGFR, leaving them unavailable to initiate the deadly twin molecu...

Researchers Identify Sipa 1 Gene, Responsible For Cancer Metastasis

...o threonine substitution in a protein-protein interaction domain known as a pdz domain. Sipa1 is a mitogen inducidble gene that encodes a GTPase acti...ly been found to interact with the water channel aquaporin 2 (AQP2), by its pdz domain, so the authors used AQP2 to see if the Alanine to threonine substit...
PDZ in Biological News

'Disordered' amino acids may really be there to provide wiggle room for signaling protein

...ions of the protein are comprised of two so-called pdz domains components well known to scientists as an...nveniently fits into a cleft on the surface of the pdz domains, but assumes a helical structure, which is...enable the protein to work. That is, it allows the pdz binding module to "bite" its own ezrin-binding tai...

Arbor Vita presents new data on cancer diagnostic at EUrogin

...rvical Cancer Programs Johannes Schweizer, Ph.D., presented results of a prototype rapid cervical cancer diagnostic test that was designed using AVC's pdz discovery platform. This E6 strip test, now in development, detects the E6 oncoprotein produced by the human papillomavirus (HPV), the principal cause...

Arbor Vita and WRAIR sign CRADA for traumatic brain injury collaboration

...NA-1 is an investigational compound that targets a pdz protein and is in clinical trials for the treatmen...as a novel drug development strategy targeting the pdz family of proteins critical elements that organiz...any signaling pathways in cells. The disruption of pdz interactions provides a means to control specific ...

Arbor Vita rapid H5N1 flu diagnostic presented at ICEID meeting

...rotein (NP). Antigen capture is mediated through a pdz protein, which binds the C-terminal region of the ...NS1 protein differs for each influenza sub-type, a pdz protein with high affinity to NS1 protein of H5 st...the role of the capture antibody is performed by a pdz protein, which provides superior specificity and b...
PDZ in Biological Technology

Dr. Linda McAllister Joins Arbor Vita Corporation as Vice President of Diagnostics

...a management team, and to help translate the company's elegant and powerful pdz biology from research to the clinic," stated Linda McAllister, M.D., Ph.D. ...agnostics addressing disease through a new family of targets, PDZ proteins. pdz proteins are critical elements that organize and regulate many signaling pa...
PDZ in Biological Products

Mouse Anti-PSD-95, PDZ Domain Monoclonal Antibody, Unconjugated, Clone K28/86.2 from Upstate

Description: Anti-PSD-95, clone K28/86.2, PDZ Domain GenBank Accession Number : NM_007864 Immunogen : GST fusion to residues 77-299 of human-PSD-95 (PDZ Domain) Formulation: 0.01M Tris pH 7.4, 0.075M NaCl containing 0.05% sodium azide Quality Assurance: routinely evaluated by immunoblot on rat brain microsoma...
Company:Upstate

Rabbit Anti-Mint3 Polyclonal Antibody, Unconjugated from ABR-Affinity BioReagents

Description:...ct with munc-18. Mint3 has been found to interact with the Alzheimers Disease-related amyloid precursor protein (APP) and does so through its PTB and pdz domains. It has been suggested that mint3 links APP to other transport machinery components, thereby regulating it transport, endocytosis, and metabo...
Company:ABR-Affinity BioReagents
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(Date:4/17/2015)... WA (PRWEB) April 17, 2015 ERGO-Pedic ... cushions is introducing two new products to help a ... low back pain relief are the second most common ... our first product, designed specifically to help relieve sitting ... Comfort Cushion, and thousands of happy customers later, we ...
(Date:4/17/2015)... April 17, 2015 Alcohol and Violence ... (NCADD) notes that drinking and driving has been the ... the same time, the link between alcohol and crime ... abuse and violence and sexual assault, and their relationship ... the NCADD, 5.3 million adults in America were drinking ...
(Date:4/17/2015)... “We have seen healing, a lot of healing, ... said Chaplain Shawn Kafader of Friendship Village. “People have ... anything to contribute have created beautiful pieces of art.” For ... therapy program that was launched to benefit residents of the ... of the Art Institute in Chicago, worked as an intern ...
(Date:4/17/2015)... In Defense of Christians (IDC) Executive Director ... April 15th, the European Parliament joined its voice with ... Armenian Genocide, “paying tribute, on the eve of the ... Armenian victims who perished in the Ottoman Empire.” ... this timely and needed recognition of a tragic episode ...
(Date:4/17/2015)... 17, 2015 Representatives Jim Himes (D-CT) ... Treatment Act HR 1849 in congress on April 16, ... treatment for patients with the genetic disease. , ... would be the first to create a federally led ... of hereditary hemorrhagic telangiectasia. This would effectively prevent premature ...
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(Date:4/1/2015)... , Apr. 1, 2015  NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market, ... Wocket smart wallets is underway to early access pre-order ... group includes usage at retail outlets including Walmart, Target, ... Users report Wocket was accepted at all outlets and ...
(Date:3/26/2015)... 2015 The Granite Club, ... athletic club, today announced it has implemented a state-of-the-art ... movement for members and staff, while restricting access to ... we selected FST,s IMID Access system because it has ... members and staff, in addition to unparalleled security," said ...
(Date:3/23/2015)... BOSTON, Mass , March 23, 2015 SoundView ... shipment of NXT-ID,s (NASDAQ: NXTD ) Wocket smart wallet. SoundView ... world user feedback on their experience with the Wocket in ... experience at CVS, Whole Foods and other retailers, making both ... Kris Tuttle also says, "If the company meets ...
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