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PARP1 in Medical News

Targeting PARP1 Is Effective In Protecting HD Cells from Damage

According to a study conducted by the researchers at the MassGeneral Institute for Neurodegenerative Disease (MIND) it was found that inhibitor of an enzyme known as Poly //(ADP-ribose) polymerase (PARP1) is very effective in protecting Huntington’s disease affected cells from undergoing damage. ...

MDOUTLOOK(R) Quick Polls Report on Clinical Integration of Key Oncology Developments Following ASCO 2009

...er: High level of excitement surrounds the development of parp1 inhibitors BSI-201 and olaparib for the treatment of triple-negative breast cancer. Development of parp1 inhibitors is expected to double the amount of genetic screening for Breast...
PARP1 in Medical Technology

BiPar Sciences Expands Clinical Development of BSI-201, A Novel PARP Inhibitor, With Phase 2 Trial in Uterine Cancer

...identification of mixed mullerian tumors of the uterus as a target for its PARP inhibitor was the result of BiPar's ground-breaking work that assessed parp1 gene expression across all types of human cancers. Striking up- regulation of the PARP gene was a characteristic of cancer of female reproductive orga...
PARP1 in other areas

PARP1 - Wikipedia, the free encyclopedia

PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. ... "Entrez Gene: PARP1 poly (ADP-ribose) polymerase family, member 1" ...

PARP1 Gene - GeneCards | PARP1 Protein | PARP1 Antibody

Complete information for PARP1 gene (protein-coding), poly (ADP-ribose) polymerase 1 ... PARP1 Gene in genomic location: bands according to Ensembl, locations ...

Ensembl genome browser 55: H.sapiens - Gene summary - Gene: PARP1 ...

Gene: PARP1. Gene-based displays. Gene summary. Splice variants (4) Supporting evidence ... Gene: PARP1 (ENSG00000143799) ... PARP1 (HGNC (curated)) Synonyms ...

SNP linked to Gene PARP1(geneID:142) Via Contig Annotation

Database of Single Nucleotide Polymorphism ... SNP linked to Gene PARP1(geneID:142) Via Contig Annotation. rs# on all gene models to Batch Query ...

Poly (ADP-ribose) polymerase 1 (PARP1)

Cow protein-coding gene PARP1. Represented by 162 ESTs from 49 cDNA libraries. ... Bos taurus poly (ADP-ribose) polymerase 1 (PARP1), mRNA. P. X06987.1 ...

Role of Poly(ADP-Ribose)Polymerase in Chromatin Programming and ...

expression of inactive PARP1 protein has been implicated in ... functionally analyzed for influence on PARP1, using standard genetic approaches combined with ...
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