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PALB2 in Medical News

Mutation In PALB2 Elevates Risk of Cancer

Cancer is a complex and common disease caused by a combination of both genetic and environmental factors. Recent research shows that the constitutional mutation in PALB2 gene elevates the risk of breast cancer four-fold. // Previous studies have shown that genes are responsible for at lea...

'Personalized' genome sequencing reveals coding error in gene for inherited pancreatic cancer

...eatic cancer to locate a mutation in a gene called palb2 that is responsible for initiating the disease. T...midine. The research team then scanned for the palb2 gene in 96 other individuals with pancreatic cance...ic cancer. Three of them had coding errors in the palb2 gene that shortened the protein in a similar way. ...
PALB2 in Biological News

Gene elevating breast cancer risk also causes prostate cancer

...in Boston identified a novel BRCA2 binding factor, palb2 that regulates certain key functions of normal BRC...step was to set out to evaluate the newly detected palb2 gene as a potential heritable breast cancer suscep...ncer families. The same constitutional mutation in palb2 was observed in three families. It was later showe...
PALB2 in other areas

PALB2 - Wikipedia, the free encyclopedia

Partner and localizer of BRCA2, also known as PALB2, is a protein which in humans is encoded by the PALB2 gene.

PALB2 - partner and localizer of BRCA2 - Genetics Home Reference

Because PALB2 and BRCA2 help control the rate of cell growth and division, these ... breast cancer - associated with the PALB2 gene ...

PALB2 Gene - GeneCards | PALB2 Protein | PALB2 Antibody

Complete information for PALB2 gene (protein-coding), partner and localizer of BRCA2 ... PALB2 Gene in genomic location: bands according to Ensembl, locations ...

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PALB2 antibody (ab38742) | Abcam

PALB2 c... PALB2 (partner and localizer of BRCA2) was identified as a protein that ... PALB2 colocalizes with BRCA2 to nuclear foci. ...
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