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A gene's first 'kiss' sets off that affair known as puberty

Puberty, that awkward phase when boys and girls are primed for their sexual reproductive years as men and women, appears to be triggered by the brain's own version of "It takes two to tango," whereby a signal literally gets turned on by a molecule that is produced by a gene aptly named KiSS-1. The couple ?a biochemical equivalent to Adam and Eve ?makes its sudden appearance in a region of...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

In a finding that broadens our insight intothe cause of certain kinds of UV-induced skin cancer, researchers atErasmus University Medical Center (Rotterdam, The Netherlands) haveemployed an evolutionarily ancient enzyme-repair system to identify theprincipal type of DNA damage responsible for the onset of skin-tumordevelopment. The researchers' findings also suggest that this enzymesystem m...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

Mount Sinai School of Medicine researchers demonstrated that a gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina. The study, which was fund...

Growth in the sea comes down to a struggle for iron

Scientists know that injecting iron into some major regions of the oceans can stimulate the growth of diatoms and other phytoplankton, but something odd occurs as these tiny marine plants continue to grow. They begin to starve in the midst of plenty, acting as though iron, an essential nutrient, still is in short supply. Why this happens is unclear, but the answer could be that iron sets off a ki...

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McCown's Woody Plant Basal Salt Mixture from Sigma-Aldrich

Description:Formula variant: With the macro- and micronutrients as described by Lloyd and McCown (1981). Suitab tst: plant cell culture tested...
Company:Sigma-Aldrich

Down Draft Work Station from Terra Universal, Inc.

Description:Ideal for chemical processing that requires downward flow of exhaust fumes. Powderful 1200 CFM blower draws fumes into sub-surface bonded charcoal filter for safe removal of organic vapors (final HEPA filter also available)....
Company:Terra Universal, Inc.

Brownlee Electrophysiology Amplifier Model 410 from AutoMate Scientific, Inc

Description:The Brownlee Precision Model 410 is a four-channel general purpose laboratory amplifier. It can be used to amplify small signals from sources which may have a large common-mode level and high frequency noise. Each channel consists of a high gain/low noise amplifier, an input coupling selector, a 2-pole lowpass filter, and an output offset control. A control knob sets the amplifier parameters and...
Company:AutoMate Scientific, Inc

Brownlee Electrophysiology Amplifier Model 440 with signal conditioner from AutoMate Scientific, Inc

Description:The Brownlee Precision Model 440 incorporates four channels of sophisticated amplifier and filter circuitry in a friendly easy-to-use instrument. Each channel consists of a high gain/low noise amplifier, an 8-pole Bessel lowpass filter, a highpass filter, a line notch filter, and output offset controls. A control knob sets the amplifier parameters and the values are displayed on a bright LED alph...
Company:AutoMate Scientific, Inc

ANTIGEN-DOWN ASSAY DILUENT from AbD Serotec

Description:Form: Ready to use Applications: ELISA...
Company:AbD Serotec

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Measuring siRNA-mediated knockdown of IL-8 mRNA

By Genospectra, Inc., 6519 Dumbarton Circle, Fremont, CA 94555. A critical step in siRNA-mediated gene expression knockdown studies is the validation of expression inhibition. The QuantiGene Reagent System and the Molecular Devices LMax II microplate luminometer were used to measure IL-8 mRNA in PMA-induced HeLa cells, following siRNA t...

Who owns software developed for your company?

Even when there is a written contract, the specifics of ownership of the intellectual property in the software are often no...

UW scientist wins Pew grant to study little-known immune cells

Jenny Gumperz, an assistant professor of medical microbiology and immunology, will receive $60,000 per year for the next four years from the Pew Charitable Trusts, an independent nonprofit organization that annua...

Rodney Dykehouse of Froedtert and Medical College of Wisconsin warns against tech for its own sake

For the CIO, implementing electronic medical r...

Housekeeping Genes: Universal Positive Controls in siRNA Knockdown Experiments

RNA interference is a powerful technique for geneknockdown experiments in academic research and animportant tool for target identification and target validationin therapeutic research. A growing number of different cell lines are us...

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Mutational meltdown

and decline of the population size, which leads to further accumulation of deleterious mutations. A population experiencing mutational...

Down syndrome

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Crowning glory of 2000!!! Cracking of the genetic code is top of tops

With the New Year elbowing out the old year it is time to reflect on the good old year and all the research work of 2000. And when we do that the first and foremost medical breakthrough, which comes to our mind, is the cracking of the genetic code. Almost all the top ten lists released by every one connected with the world of medicine features this remarkable feat in a prominent place and...

Cut down TV and video games and you have less aggressive children.

Have you ever wondered why your kids are so aggressive and almost impossible to handle at times? Then read on. World over there is increasing concern over the way the children of today are growing up. Even the West is getting desperate and looking for help. Things are no better in India. With the TV boom and the IT revolution, the kids seem to know all at a very young age and many parent...

Chinese Students Affected By Unknown Flu

Around 400 Chinese students belonging to Henan University of Science and Technology at Luoyang, suffered from high fevers and were rushed for treatment. The nature of the high fever is suspected to be of unknown flu virus, reports foodconsumer.org. // Reporters can still see a couple of ambulances waiting on the university campus to respond to any emergency needs. It remains u...

Hormone treatment helps obese people slim down

Treatment with leptin, a natural hormone that helps control body weight, could help many overweight people slim down. Discovered in 1994, leptin is normally produced by fat cells and is believed to provide a signal about the amount of body fat to the body's energy-regulation system. // Leptin treatment has already helped people who completely lack the hormone because of a genetic muta...

Early Clue to Down Syndrome

Down syndrome, also known as trisomy 21, is a chromosomal disorder occurring in roughly one in every 800 live births. The condition produces varying degrees of mental retardation and a range of physical deformities, including a small nose and thick neck, which are detectable more or less in early pregnancy. Detecting Down syndrome early in pregnancy could be as plain as the nose on the ba...

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Full Handle Laseredge Crescent Blade Knife, angled bevel down

Description:Full Handle Laseredge Crescent Blade Knife, angled bevel down. Blade tip dimension: 12.7 mm x 2.0 mm x 3.8 mm....
Company:Bausch & Lomb Storz

Sandown chair

Description:Sandown chair, with hydraulic lift, sliding headrest and armrests with glides. Black vinyl....
Company:Clement Clarke International

Blair-Brown Skin Graft Knife

Description:165 mm long blade. 17 mm wide blade. Overall length 305 mm, 12.0 inches. Note: Has Marcks attachment for right and left-hand cutting to any thickness up to .035 inches (.89 mm). For thicker grafts or split graft. Marcks attachment can be easily removed for free-hand cutting....
Company:Bausch & Lomb Storz

Blair-Brown Blade Only

Description:Disposable. For use with the N4086....
Company:Bausch & Lomb Storz

Brown Nucleus Cracker

Description:Brown nucleus cracker with straight shaft allows cracking with minimal loss of viscoelastic, thereby, maintains anterior chamber depth and prevents peripheral extension of capsulorhexis. Accomplished with a design that keeps cross point of instrument in wound, blocking outflow of viscoelastic. Available with 1.5 mm x 1.2 mm paddle style tips....
Company:Duckworth & Kent Ltd.

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RTA 402 Shown to Protect Animals Against Toxicities of Standard Cancer Treatments

IRVING, Texas--(BUSINESS WIRE)--Jun 29, 2007 - ReataPharmaceuticals, Inc. today announced the presentation of newpreclinical data showing their lead anti-cancer agent, theSynthetic Triterpenoid RTA 402, is effective at protecting againstcommon toxicities caused by traditional cancer treatments. Thisdata was presented at the annual meeting of the MultinationalAssociation of Supportive Care i...

Gabapentin Shown Effective for Fibromyalgia Pain

BETHESDA, Md., June 11, 2007--New research supported by theNational Institutes of Healths National Institute of Arthritis andMusculoskeletal and Skin Diseases (NIAMS) shows that theanticonvulsant medication , which is used for certaintypes of seizures, can be an effective treatment for the pain andother symptoms associ...

Breaking Multi-Center Study: Masimo SET Pulse Oximetry Technology Shown to Significantly Lower Instances of Severe Retinopathy of Prematurity in Extremely Low Birth Weight Infants

Study released at the Pediatric Academic Societies' Annual MeetingThis Month in Toronto Shows That Switching to Masimo SET PulseOximetry Technology Can Reduce the Risk Associated with ROP by 40% IRVINE, Calif., May 30, 2007 /PRNewswire/ -- Masimo, theinventor of Pulse CO-Oximetry and Read-Through Motion and LowPerfusion pulse oximetry, reported that a new independent studypresented at the...

CEL-SCI'S CEL-1000 Shown to Significantly Enhance Immune Response Against Avian Flu Antigen in Animals

VIENNA, Va., May 23, 2007 /PRNewswire-FirstCall/ -- CEL-SCICORPORATION announces that CEL-1000 increased the immune responseagainst H5 avian influenza antigen in combination with MAS-1, awater-in-oil adjuvant delivery system. These findings werepresented on May 23, 2007 by Dr. Daniel Zimmerman, Senior VicePresident of Research, Cellular Immunology at CEL-SCI at theAmerican Society of Mic...

MIV Therapeutics Announces Renowned Researcher to Detail Milestone Pre-Clinical Results at Prominent International Conference EuroPCR 2007

ATLANTA--(BUSINESS WIRE)--May 22, 2007 - MIV Therapeutics(OTCBB:MIVT) (FWB:MIV), a leading developer of next generationbiocompatible coatings and advanced drug delivery systems forCardiovascular stents and other implantable medical devices, ispleased to announce that results from an animal trial comparing itsproprietary polymer free Hydroxyapatite-coated drug-elutingcardiovascular stent to...

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