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Overcomes in Medical News
Penn researchers find targeted therapy combination overcomes treatment resistance in liver cancer
SAN DIEGO Researchers at the University of Pennsylvania School of Medicine and Abramson Cancer Center reported today at the annual meeting of the American Association for Cancer Research that combining two targeted therapies overcomes treatment resistance in liver cancer cell lines. The team is c...Drug-coated balloon overcomes in-stent restenosis
CHICAGO, Ill. (March 31, 2008) An angioplasty balloon coated with a drug that reduces renarrowing of the coronary arteries appears to be more effective than a drug-eluting stent in treating an unwanted build-up of tissue inside a bare-metal coronary stent. After six months, the newly expanded art...Gene Therapy Overcomes Heart Failure In Muscular Dystrophy
Researchers at the University of Pittsburgh have successfully treated heart failure in an animal model that is genetically //prone to develop a human muscular dystrophy. The article detailing this study is published in the Oct. 25 edition of the journal Circulation. The authors say that this is the......and partners have experienced -- that there are significant challenges in governing product data and that our break-through semantic technology easily overcomes those challenges," stated Barbara Mowry, president and CEO of Silver Creek Systems. "This recognition continues to reflect the uniqueness of...
...Solutions Manager at Brooks Instrument. "Each DLI vaporizer is easily customizable for every customer's unique application requirements and also overcomes the many operational limitations of conventional vaporizing technologies such as bubblers, or vapor draw systems, and flash vaporizers. Additionally, ...
...solved in solvents, which led to low tolerability and severe adverse effects in dogs. Paccal Vet uses a novel, non-toxic nanoparticle formulation that overcomes those challenges and provides a high level of water solubility. If approved, Paccal Vet would be one of the first cancer treatments specifically desi...
...create the highest insulating material in existence. Previously, aerogel had been difficult to adapt to most uses because of its fragility. Thermablok overcomes this by using a unique patented fiber to suspend a proprietary formula of aerogel so that it can be bent or compressed while still retaining its insul...
...ombating substance abuse. The kit is now available at a local Discount Drug Mart Store. Developed by Biotech Company Confirm BioSciences, the test overcomes the limitations of two- or three-day saliva or urine screenings that enable users to escape detection by avoiding drug use for a short period. It is a...
...ulmonary exercise testing has limited its utility and deprived physicians and their patients of much needed physiological information. Shape-HF™ overcomes these limitations. It provides objective data to the cardiologist right in the office or clinic. The test is easy on patients and the equipment is int...
ThinIdentity(TM) Announces Two New Board Members
... executives expressed to me their frustrations with current technology and the difficulties of full adoption by healthcare professionals. ThinIdentity overcomes these obstacles and will be a leader in the healthcare market helping to drive the "meaningful use" of Electronic Medical Records which in turn will r...Overcomes in Medical Technology
Alfacell Provides Shareholder Update
...didate that works in a manner similar to RNA interference (RNAi) through late-stage clinical trials. The product candidate, ONCONASE, is an RNase that overcomes the challenges of targeting RNA for therapeutic purposes while enabling the development of a new class of targeted therapies for cancer and other life...Ascenta Therapeutics Announces Multiple Presentations on AT-101 at 2009 ASCO Annual Meeting
...537; Publication only. Mechanism of Action/Pharmacokinetics Wang S, et al. AT-101 induces transcriptional up-regulation of Noxa and Puma and overcomes Mcl-1-mediated cancer cell resistance to apoptosis. Abstract # e14611; Publication only. Pitot H, et al. Analysis of a phase I pharmacokinetic ......herapy consistent with survival data we have previously generated in two independent Phase 2 trials. We also expect the data will show that picoplatin overcomes resistance in patients treated with current platinum-based chemotherapies. This would be a new use for a platinum chemotherapy agent. We are also cont...
Abbott and Enanta Initiate Phase 1 Clinical Trial on ABT-450 HCV Protease Inhibitor
... targeted against the Hepatitis C virus (HCV). Additionally, the company has created a new class of macrolide antibiotics, called Bicyclolides, which overcomes bacterial resistance. Antibacterial focus areas include superbugs, respiratory tract infections and intravenous and oral treatments for hospital and ...Alfacell Provides ONCONASE(R) NDA Submission Update
...didate that works in a manner similar to RNA interference (RNAi) through late-stage clinical trials. The product candidate, ONCONASE, is an RNase that overcomes the challenges of targeting RNA for therapeutic purposes while enabling the development of a new class of targeted therapies for cancer and other life......ced new clinical data that demonstrate PRT060128, the Company's novel anti-platelet drug that directly and reversibly inhibits the P2Y12 ADP receptor, overcomes high platelet reactivity (HPR) in patients who do not respond to clopidogrel (Plavix(R)). The results [Abstract #5603] were presented at the American ...
...Hall A-B1, Poster Board B129 Wednesday, November 12 Poster Title: "Oral Dosing of PRT060128, a Novel Direct-acting, Reversible P2Y12 Antagonist overcomes High Platelet Reactivity in Patients Non-responsive to Clopidogrel Therapy" Paul A. Gurbel et al Time: 9:00 a.m. - 5:00 p.m. Hall A-B1, Poste...
...s targeted against the Hepatitis C virus (HCV). Additionally, the Company has created a new class of macrolide antibiotics, called Bicyclolides, which overcomes bacterial resistance. Antibacterial focus areas include superbugs, respiratory tract infections, and intravenous and oral treatments for hospital and ...
...didate that works in a manner similar to RNA interference (RNAi) through late-stage clinical trials. The product candidate, ONCONASE, is an RNase that overcomes the challenges of targeting RNA for therapeutic purposes while enabling the development of a new class of targeted therapies for cancer and other life...
Alfacell Announces ONCONASE(R) Distribution and Marketing Agreement with Megapharm for Israel
...didate that works in a manner similar to RNA interference (RNAi) through late-stage clinical trials. The product candidate, ONCONASE, is an RNase that overcomes the challenges of targeting RNA for therapeutic purposes while enabling the development of a new class of targeted therapies for cancer and other life...Overcomes in Medical Products
Chronos Granules Bone Graft Substitute
Description:...s bone graft substitute (beta-tricalcium phosphate). The use of Chronos is an advantageous alternative to bone harvesting. It shortens operative time, overcomes the limitations in quantity and quality of available bone graft and avoids donor site morbidity....Company:Synthes, Inc.
Finstruments 96 well washer and Cellwasher
Features:...d by user. Can be used with various plate types by adjusting height, onboard pump provides gentle dispensing and agitation. Perfect for cell washings, overcomes the limitations of gravity feed systems, comes with MTX Labs upgrade 2 liter supply reservoir(s), external pump and waste reservoir. Easy user mainten...Company:MTX Labs Inc.
Overcomes in Biological News
Meteorology student SOARS toward excellence, overcomes obstacles
VIRGINIA KEY, Fla. Roque Vinicio Cspedes, a junior at the University of Miami double majoring in Meteorology and Applied Mathematics, with a minor in Spanish, has been awarded a prestigious Significant Opportunities in Atmospheric Research and Science (SOARS) mentorship. SOARS is a paid summer re...Faster, more cost-effective DNA test for crime scenes, disease diagnosis
...sive and cumbersome for wide use. The scientists describe development and testing of a new PCR method, called the universal QProbe system, that overcomes these problems. Existing PCR processes require several "fluorescent probes" to seek out DNA. QProbe substitutes a single "fluorescent probe" that can ...... the ship's motion, only point into the sky for much of the time. A new thermal imager developed by Rheinmetall Defence Electronics, Bremen, Germany overcomes these challenges. The system, called FIRST Navy, was installed during Polarstern's last port call on a highly stabilized platform in the ship's crow's...
Moving gene therapy forward with mobile DNA
...n with Zsuzsanna Iszvak and Zoltan Ivics and colleagues at the Max Delbrck Center in Berlin (Germany) have now developed a new non-viral approach that overcomes some of the limitations associated with viral vectors. Lessons from evolution Using the principles of evolution and natural selection, that wer...American Chemical Society Weekly PressPac -- April 15, 2009
...he necessity of a complex analytical apparatus. Serra and colleagues describe development and testing in laboratory rats of a wireless sensor that overcomes some of those drawbacks. The scientists used a variety of techniques including physiological stimuli and pharmacological treatments to raise or lowe...HIV dearms protective protein in cells
...s are tethered to the cell surface when they are in the process of leaving the cell and this prevents them from infecting other cells of the body. HIV overcomes this restriction by its protein Vpu by specifically counteracting this protective mechanism, which, interestingly, is effective against many types of ...Queen's researchers shine light on compact fluorescent bulb problems
.... The solutions emerged when John Lam, a PhD candidate working with Dr. Jain, developed a compact, simplified circuitry and controller design that overcomes the power problem while also meeting consumers' need for a dimmable, inexpensive CFL. "Understanding the significance of the problem motivated me to w...Mount Sinai Hospital researcher makes stem cell breakthrough
...e use of viruses to deliver the required genes, a method that carries the risk of damaging the DNA. Dr. Nagy's method does not require viruses, and so overcomes a major hurdle for the future of safe, personalized stem cell therapies in humans. "This research is a huge step forward on the path to new stem c...TECNALIA uses artificial vision to improve recycling of electronic scrap metal
...scrap metal from electronic waste based on a system of multispectral vision and incorporate it into the process of a recycling plant. This new machine overcomes the limitations of current, basically manual, methods which consume a large amount of manual labour and time and which are unable to separate metals w...UD research study to shed light on emerging seaborne pathogen
...osafety grant from the U.S. Department of Agriculture (USDA), is to home in on this emerging pathogen's virulence genes and determine how the organism overcomes its victim's immune system -- information that can then be used to combat, detect and prevent infection. The aquaculture industry loses millions of...Overcomes in Biological Technology
Junying Yu, Leading Stem Cell Researcher, Joins Cellular Dynamics International
...logically relevant models arising from non-human animal models or models that do not appropriately reflect the target population. iPS cell technology overcomes these obstacles and offers the promise of generating differentiated cell types from virtually any genetic background." Yu Leads iPS Cell Bre...LS9's UltraClean Diesel Exceeds United States & Brazilian Fuels Specifications
...the regulatory criteria needed for use in vehicles on American and Brazilian roads today. These tests also indicate that LS9 UltraClean™ Diesel overcomes key environmental and operational challenges associated with conventional diesel and biodiesel products. LS9 UltraClean™ Diesel offers signi...Cellular Dynamics International and Roche Expand Existing Cardiotoxicity Screening Agreement
...ns associated with current in vitro testing models that do not appropriately reflect the target cell population and physiology. Our iPSC technology overcomes these obstacles and offers the promise of generating differentiated cell types, even personalized cell types, from virtually any genetic background. W......ts as a barrier to cell division and proliferation. However, when Raf-1 physically interacts with Rb, it triggers a cascade of signals that eventually overcomes this barrier, thus inducing cellular proliferation. By preventing the interaction between Raf-1 and Rb and blocking the cell cycle, Debio 0928 creates...
Cappella Inc. Secures $17.3 Million Series C Investment
...ique peel-away delivery system. Both the stent and this delivery system were developed by Cappella Medical Devices Ltd. The unique delivery technology overcomes a number of delivery problems associated with existing nitinol stents, including reduced profile and improved placement accuracy over traditional deli......uous basis by means of the Company's proprietary Encapsulated Cell Technology (ECT) platform. Delivery via ECT bypasses the blood-retinal barrier and overcomes a major obstacle in the treatment of retinal disease. The two Phase 2 studies were multi-centered, randomized, double-masked, sham-controlled do...
...ulmonary exercise testing has limited its utility and deprived physicians and their patients of much needed physiological information. Shape-HF™ overcomes these limitations. It provides objective data to the cardiologist right in the office or clinic. The test is easy on patients and the equipment is int...
Providence-Based NABsys, Inc., Announces $4 Million Equity Financing
...whole-genome DNA sequencing has remained far too expensive, slow, and inaccurate to be used in clinical care. NABsys' electronic, solid-state approach overcomes these limitations. "The technological advantages that the NABsys platform enjoys, namely electronic detection, the use of all solid-state materia...Xspray Expands to Meet Pharma's Interest in its Ground-Breaking Particle Production Technology
...dge solution for pharmaceutical particle production based on supercritical fluid technology. The Company's RightSize Particle Manufacturing Technology overcomes many of the drawbacks of traditional micronization and is well suited to demanding applications. As well as offering all the advantages of earlier sup...New imaging technique reveals the atomic structure of nanocrystals
... CHAMPAIGN, Ill. A new imaging technique developed by researchers at the University of Illinois overcomes the limit of diffraction and can reveal the atomic structure of a single nanocrystal with a resolution of less than one angstrom (less than one hundre...Overcomes in Biological Products
ViraPower UbC Lentiviral Gateway Expression Kit from Invitrogen
Description:...y mammalian cell types and experimental situations create challenges for standard transfection experiments. The ViraPower Lentiviral Expression System overcomes these challenges with efficient...Company:Invitrogen
ViraPower Lentiviral Packaging Mix from Invitrogen
Description:...y mammalian cell types and experimental situations create challenges for standard transfection experiments. The ViraPower Lentiviral Expression System overcomes these challenges with efficient viral deliver...Company:Invitrogen
293FT Cell Line from Invitrogen
Description:...s and experimental situations create challenges for standard transfection and other viral transduction systems. ViraPower Lentiviral Expression System overcomes these challenges by efficiently transduci...Company:Invitrogen
pLenti6/V5 Directional TOPO Cloning Kit from Invitrogen
Description:...s and experimental situations create challenges for standard transfection and other viral transduction systems. ViraPower Lentiviral Expression System overcomes these challenges by efficiently transduci...Company:Invitrogen
GenomeLab GeXP Genetic Analysis System from Beckman Coulter
Description:...Analysis System provides high-throughput, quantitative gene expression analysis via scalable, multiplexed PCR*. The systems patented priming strategy overcomes the biases that limit standard multiplexed PCR analysis to just a few genes at a time. GenomeLab GeXP delivers more genes per reaction and more sampl...Company:Beckman Coulter
MIDAS TRAQ System with 4000 Q TRAP LC/MS/MS System from Applied Biosystems
Description:...iomarker prediction, profiling, and discovery experiments to assays for biomarker verification and validation. The workflow for biomarker verification overcomes the need for separate methods development, including protein or peptide standards, for each potential biomarker. Quantitatively Validate Candidate ...Company:Applied Biosystems
Extracti-Gel D Detergent Removing Gel AffinityPak Columns from Pierce Biotechnology, Inc.
Description:...he gel matrix, where they interact with a specially developed ligand capable of removing them from solution Low exclusion limit of the base support overcomes the possibility of nonspecific binding by not permitting larger macromolecules to enter the gel; detergent is extracted with high efficiency without f...Company:Pierce Biotechnology, Inc.
MicroBeta Filtermat-96 Harvester from PerkinElmer
Description:...ire harvesting process. No more overfilling, no tedious programming steps, and you can segregate hot and cold waste. And, FilterMates short fluid path overcomes the problems of dissociation, clogging, and contamination. Key Features: Speed and simplicity are the primary strengths of the FilterMate Harvester. ...Company:PerkinElmer
Overcomes in Biological Dictionary
...isms of resistance for characterized tet and otr genesa ... Distribution of tet resistance genes among gram-negative bacteriaa ... PTK 0796 overcomes tet resistance mechanisms in gram-positive bacteria as ... status of tet susceptibility of the test organisms, mutational resistance to PTK ...
...n microarrays by performing in vitro synthesis of the target proteins from their DNA templates. This method of synthesizing protein microarrays overcomes the many obstacles... Protein arrays are rapidly becoming established as a powerful means to detect ... The objective behind protein array...
... dissolved in a "mobile phase" through a stationary phase, which separates the analyte to... Affinity chromatography is a method that overcomes this limitation by exploiting ... affinity chromatography and their complementary ligands are listed in Table 1. ... What is Affinity chroma...
...n microarrays by performing in vitro synthesis of the target proteins from their DNA templates. This method of synthesizing protein microarrays overcomes the many obstacles... Protein arrays are rapidly becoming established as a powerful means to detect ... The objective behind protein array...
... dissolved in a "mobile phase" through a stationary phase, which separates the analyte to... Affinity chromatography is a method that overcomes this limitation by exploiting ... affinity chromatography and their complementary ligands are listed in Table 1. ... What is Affinity chroma...
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[1] Roche Announces Shipments of New Supplies of Children's Tamiflu in the U.S. [0] Antidepressants May Change Your Personality[1] Orion Health Participates in International Forum to Break Down Barriers for Health Information Exchange[0] The Dignity Memorial(R) Network Honors Four Individuals Who Gave the Gift of Life Through Organ and Tissue Donation[1] Genetic variations indicate risk of recurrence, secondary cancer among head and neck cancer patients
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