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Ovarian in Medical News

Many Opt for Surgery to Lower Breast, Ovarian Cancer Risk

Women with BRCA gene mutations often choose preventive measures, study finds FRIDAY, Aug. 7 (HealthDay News) -- Many women with a high risk of breast or ovarian cancer have surgery to remove their breasts or ovaries in order to reduce the likelihood of developing cancer, English resear...

'Suicide' Genes Help Slow Ovarian Tumor Growth in Mice

Treatment could be tested in women within 18 to 24 months, expert suggests THURSDAY, July 30 (HealthDay News) -- Treatment with "suicide" genes slowed ovarian tumor growth in mice and may one day offer a way to treat late-stage ovarian cancer in women, U.S. scientists say. Currently...

Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth

Potential late-stage ovarian cancer therapy; currently none available; Diphtheria-encoding genes delivered to tumor site by nanoparticles; Laboratory research; possible human trials about 18 months away Philadelphia (Vocus) July 29, 2009 -- Nanoparticle delivery of diph...

JNCI news brief: Antibody linked to chemotherapy drug inhibits ovarian cancer in lab

A novel anticancer agent, consisting of a monoclonal antibody linked to a chemotherapy drug, showed substantial antitumor activity in ovarian cancer cell lines and in mice, according to a study published online July 29 in the Journal of the National Cancer Institute . The agent, known as an im...

New Diagnostic Biomarker Test Shows Promise in Monitoring Ovarian Cancer

CHICAGO, July 22 /PRNewswire-FirstCall/ -- Ovarian malignancies are a leading cause of cancer death in women because they are usually detected in the late stages when the disease is incurable. Encouraging new research presented by Abbott today at the American Association for Clinical Ch...

Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding Trabectedin for Relapsed Ovarian Cancer

HORSHAM, Pa., July 15 /PRNewswire/ -- Based on the data presented today, the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) recommended that the combination of trabectedin when administered with DOXIL(R) (doxorubicin HCI liposome injection) did not provide a...

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Ovarian in Medical Technology

Cancer Treatment Centers of America(R) Studies Treatment That Aims Chemotherapy Directly at Ovarian Cancer Cells

Therapy targets folate receptors found on cancer cells otherwise resistant to standard chemo ZION, Ill., June 17 /PRNewswire-USNewswire/ -- Cancer Treatment Centers of America (CTCA) at Midwestern Regional Medical Center, a leading provider of innovative cancer care for patients living wi...

Oasmia: FDA Grants Paclical(R) Orphan Drug Designation for Ovarian Cancer in the USA

UPPSALA, Sweden, April 14 /PRNewswire-FirstCall/ -- Oasmia Pharmaceutical, Uppsala, Sweden, has been granted Orphan Drug designation by the USA FDA of Paclical(R) for the treatment of ovarian cancer. Orphan Drug designation can entail additional assistance from FDA to expedite and optimize dru...

Access Pharmaceuticals Announces Positive ProLindac(TM) Phase 2 Ovarian Cancer Clinical Trial Results

66% of evaluable heavily-pretreated patients in the high dose groups achieved disease stabilization. ProLindac was well tolerated overall. DALLAS, March 5 /PRNewswire-FirstCall/ -- ACCESS PHARMACEUTICALS, INC. (OTCBB: ACCP), announced today positive safety and efficacy results from its Ph...

Pivotal Data Published For First Biomarker Combination Test to Determine Risk of Ovarian Cancer in Women Who Present With Pelvic Mass

Article in Gynecologic Oncology Supports Use of Fujirebio Diagnostics' HE4 Test with CA125 for Risk Stratification of Women with Suspected Ovarian Cancer MALVERN, Pa., Jan. 26 /PRNewswire/ -- A pivotal clinical trial published in the January 2009 issue of the journal Gynecologic Oncology ...

Sunesis Pharmaceuticals Presents Clinical Trial Data of Voreloxin in Patients with Acute Myeloid Leukemia and Ovarian Cancer at the Chemotherapy Foundation Symposium

- Voreloxin Demonstrates Promising Clinical Activity in Patients with Difficult-to-Treat Cancers - SOUTH SAN FRANCISCO, Calif., Nov. 6 /PRNewswire-FirstCall/ -- Sunesis Pharmaceuticals, Inc. (Nasdaq: SNSS ) presented data from three clinical trials of the company's lead ...

AEterna Zentaris Reaches 2nd Stage of Patient Recruitment for Phase 2 Trial in Ovarian Cancer with the Innovative LHRH Receptor Targeted Conjugate, AEZS-108

QUEBEC CITY, Oct. 2 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. (NASDAQ: AEZS ; TSX: AEZ), a global biopharmaceutical company focused on endocrine therapy and oncology, today reported that it has entered the second stage of patient recruitment for its Phase 2 trial in ovarian cancer with A...
Ovarian in Medical Products

Androstenedione EIA Test

Description:...rum androstenedione levels are also increased in polycystic ovary syndrome, ovarian stromal hyperthecosis, 3b-hydroxysteroid dehydrogenase deficiency, and othe... [3,5]. Elevated serum androstenedione levels may also occur in adrenal and ovarian virilizing tumors [3]. 1. Dorfman RI, Shipley RA: Androgens. John Wiley...
Company:Diagnostic Systems Laboratories, Inc.

Androstenedione RIA Test

Description:...rum androstenedione levels are also increased in polycystic ovary syndrome, ovarian stromal hyperthecosis, 3b-hydroxysteroid dehydrogenase deficiency, and othe... [3,5]. Elevated serum androstenedione levels may also occur in adrenal and ovarian virilizing tumors [3]. 1. Dorfman RI, Shipley RA: Androgens. John Wiley...
Company:Diagnostic Systems Laboratories, Inc.

Inhibin B ELISA Test

Description:...molecule, containing both the alpha and beta subunits, are bioactive, although the free subunit forms exist in circulation. Inhibins are secreted by ovarian granulosa cells in females and by testicular Sertoli cells in males [1]. Both inhibin A and inhibin B are produced in females, but in males inhibin B ...
Company:Diagnostic Systems Laboratories, Inc.

Inhibin A ELISA Test

Description:...molecule, containing both the alpha and beta subunits, are bioactive, although the free subunit forms exist in circulation. Inhibins are secreted by ovarian granulosa cells in females and by testicular Sertoli cells in males [1]. Both inhibin A and inhibin B are produced in females, but in males inhibin B ...
Company:Diagnostic Systems Laboratories, Inc.

MIS/AMH ELISA Test

Description:... MIS/AMH is produced by the Sertoli cells of the testis in the male, and by ovarian granulosa cells in the female. During embryonic development in males, secre...cal applications for a specific MIS/AMH assay include: the investigation of ovarian reserve and the perimenopausal transition in women; the detection and manag...
Company:Diagnostic Systems Laboratories, Inc.

Free Testosterone RIA Test

Description:...hirsutism in the presence or absence of polycystic ovarian disease [1,2,3]. In addition, free testosterone me..., 1986 Pugeat M, et al.: Androgens in polycystic ovarian syndrome. IN Tolis G, Bringer J, Chrousos GP (eds): Intraovarian regulators and polycystic ovarian syndrome. NY Academy of Sciences, New York, 1993, ...
Company:Diagnostic Systems Laboratories, Inc.
Ovarian in Medical Definition

Personalized medicine

...is BRCA mutations where the carrier can have an increased lifetime risk of 85% for developing a breast cancer or up to 40% increased risk of getting ovarian cancer. Now medications such as tamoxifen are being shown to reduce incidence of disease. The exciting news is that cancer predisposition genes and ...
Ovarian in Medical Dictionary

Virilization

... /vir·il·iza·tion/ (vir′′ĭ-lĭ-za'shun) ... virilization ... Virilization occurred three months after diagnosis of gastric cancer and the ovarian tumors. ... Virilization was absent at the time of the initial diagnosis. ... New Treatments for Hirsutism and Virilization , August 1, 2009 .....

Turner syndrome

... ... Turner syndrome results from a chromosomal abnormality. Girls with TS usually are shorter than average and infertile due to early loss of ovarian function. Turner syndrome is a chromosomal condition that alters development in females. ... This does not happen in most girls who have Turn...

Tissue

...e ... Multiple TFs work in concert to achieve tissue specificity. ... ovarian tissue transplantation information that can help make pregnancy a reality at nejm.org. ... offer to bank ovarian tissue of young patients with cancer, ... Preoperative irradiation fo...

Struma

...ictionary with audio pronunciations, thesaurus, Word of the Day, and word games. RESULT: The patients with struma ovarii constituted 1.0% of all ovarian ... Four percent of the germ cell tumors were calculated to be of struma ovarii (16/382) ... Струма е информационен сайт, който ежедневно пу...

Secondary amenorrhea

... is lack of periods for 6 or more months in a woman who has ... Polycystic ovarian syndrome is a frequent cause of secondary amenorrhea . ... Amennor... is lack of periods for 6 or more months in a woman who has ... Polycystic ovarian syndrome is a frequent cause of secondary amenorrhea . ... ...

Prolapse

...ist, a ... Womens health issues including the menopause, endometriosis, ovarian cysts, infertility, weight loss, polycystic ovarian syndrome and ... Vaginal Prolapse ... Rectal prolapse occurs when...
Ovarian in Biological News

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

PHILADELPHIA Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research , a journ...

2 reproductive factors are important predictors of death from ovarian cancer

PHILADELPHIA Researchers from the Centers for Disease Control and Prevention (CDC) found that survival among women with ovarian cancer is influenced by age of menarche and total number of lifetime ovulatory cycles. This finding suggests that hormonal activity over the course of a woman's lifet...

Genetic factors implicated in survival gap for breast, ovarian or prostate cancer

NEW YORK (July 8, 2009) A new finding reveals that African-American patients with breast, ovarian, and prostate cancer tend to die earlier than patients of other races with these cancers, even when they receive identical medical treatment and when socioeconomic factors are controlled for. The fin...

Genetic testing for breast or ovarian cancer risk may be greatly underutilized

Although a test for gene mutations known to significantly increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, a new study finds that few women with family histories of these cancers are even discussing genetic testing with their physicians or other h...

Promising new treatment option for women with recurrent ovarian cancer

Combining the new drug trabectedin with pegylated liposomal doxorubicin provides clinical benefit to women with relapsed ovarian cancer, according to new results presented at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm. The combination, which importantly ...

TG2 identified as potential therapeutic target in chemo-resistant ovarian cancer

HOUSTON, TX Scientists from The University of Texas M. D. Anderson Cancer Center have found overexpression of tissue type transglutaminase (TG2) in ovarian cancer is associated with increased tumor cell growth and adhesion, resistance to chemotherapy and lower overall survival rates. When resea...

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Ovarian in Biological Technology

ImmunoVaccine Technologies Licenses Immunotope's Breast, Ovarian and Prostate Cancer Antigens

HALIFAX, NS, July 14 /PRNewswire/ - ImmunoVaccine Technologies Inc. (IVT), a vaccine development company, has entered into an agreement to exclusively license seven cancer antigens from Immunotope Inc., an antigen discovery company. These proprietary antigens specifically target breast, ovarian an...

NFGC Conducts Multi-Institutional Research Project in Ovarian Cancer

$500,000 will be invested in the first phase of this personalized medicine initiative TAMPA, Fla., April 24 /PRNewswire/ -- The National Functional Genomics Center , funded through an assistance agreement that is awarded and administered by the U.S. Army Medical Research & Materiel...

Vermillion Announces Notice of Issuance of U.S. Patent Covering Hepcidin as a Biomarker for Ovarian Cancer

- Discovery Could Lead to the Development of a Next-Generation Assay to Improve Diagnosis and Treatment of Ovarian Cancer - FREMONT, Calif., Feb. 12 /PRNewswire-FirstCall/ -- Vermillion, Inc. (OTC Bulletin Board: VRML), a molecular diagnostics company, today announced that the U.S. Patent Off...

First Patient Dosed in Phase 2 Clinical Trial of NKTR-102 in Ovarian Cancer

SAN CARLOS, Calif., Jan. 13 /PRNewswire-FirstCall/ -- Nektar Therapeutics (Nasdaq: NKTR ) announced today that dosing has started in a Phase 2 clinical trial of NKTR-102 in platinum-resistant ovarian cancer. Regulatory approvals have also been obtained and dosing will begin shortly in two a...

Telik Announces Top-Line Results From Assist-5 Trial of Telcyta(R) in Combination With Pegylated Liposomal Doxorubicin in Platinum Refractory and Resistant Ovarian Cancer

PALO ALTO, Calif., Oct. 29 /PRNewswire-FirstCall/ -- Telik, Inc. (Nasdaq: TELK ) today announced top-line results from an interrupted Phase 3 randomized study of Telcyta (canfosfamide HCL) in combination with pegylated liposomal doxorubicin (PLD) versus PLD alone in second-line therapy in pla...

Exiqon Announces Positive Clinical Data From EORTC Clinical Trial Showing Oncotech EDR Assay Predicts Resistance to Platinum-Based Therapy in Ovarian Cancer

VEDBAEK, Denmark, October 27 /PRNewswire-FirstCall/ -- The European Organization for Research and Treatment of Cancer (EORTC) has undertaken a multi-institutional prospective randomized clinical trial on 719 late stage epithelial ovarian cancer patients (named 55971). Results were announced to...
Ovarian in Biological Products

Sf21 Frozen Cells (Grace's Media) from Invitrogen

Description:... Sf21 cells derived from Spodoptera frugiperda ovarian cells are recommended for high-level production of recombinant proteins. Higher expression levels of some proteins are seen due to the larger cell si...
Company:Invitrogen

Sf9 Frozen Cells (Grace's Media) from Invitrogen

Description:... Sf9 cells derived from Spodoptera frugiperda ovarian cells (Sf21 cells) are commonly used to isolate and propagate recombinant AcMNPV viral stocks and to produce recombinant proteins....
Company:Invitrogen

Sf21 Cells (SFM Adapted) from Invitrogen

Description:... Adapted to Sf-900 II SFM.Sf21 Cells (IPLB-Sf21-AE) were isolated from Spodoptera frugiperda (Fall Armyworm) ovarian insect cells (1). The Sf21 cells are adapted to serum-free suspension culture in Sf-900 II SFM for transient or stable expression of recombinant prote...
Company:Invitrogen

HER2plus Control Slides from European Collection of Cell Cultures (ECACC)

Description:... progresterone receptor assays. The slides consist of paraffin wax sections of formalin fixed, breast cancer cell lines; MDA-MD-361, T47D, MCF and the ovarian cell line SKOV-3. This range of cell lines provides a gradation of HER2 protein level expression around the clinically significant range. When used ...
Company:European Collection of Cell Cultures (ECACC)
Ovarian in Biological Definition

Biotechnology

...ics . It can also refer to transgenic animals or transgenic plants , such as Bt corn. Genetically altered Mammalian cells, such as Chinese Hamster ovarian cells, are also widely used to manufacture pharmaceuticals. Another promising new biotechnology application is the development of plant-made pharmace...

Cancer

...ium , oral cancer , osteosarcoma - in bones , ovarian cancer , pancreatic cancer , prostate cancer , ...n much more likely to develop breast cancer and ovarian cancer . Some types of viruses can cause mutatio...component. Examples are: breast cancer and ovarian cancer in female carriers of BRCA1 tumors of...

Infertility

...n Hyperprolactinemia Hypopituitarism ovarian factors Polycystic ovary syndrome Anovulation Diminished ovarian reserve Luteal dysfunction Premature menopause Gonadal dysgenesis ( Turner syndrome ) ovarian tumor Tubal/peritoneal factors Endometrio...
Ovarian in Biological Dictionary

Viral oncogene

...cogene homolog. KRAS1. KRAS2 ... ... leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) ... oncogene ; ovarian ; progression ; protein ; proto- oncogene ; ... Human protein-coding gene MYB. Represented by 97 ESTs from 52 ... Homo sapiens c-myb gene fo...

Proteomics

...rkshop on Proteomics . ... The term ' proteomics ' carries with it the connection to genomics and the ... A fast-tracked paper on a possible new ovarian cancer screening tool by Lance Liotta , M.D., Ph.D., National Cancer Institute (NCI), and Emanuel Petricoin, M.D. ... Agilent provides targeted...

Ovulation

... Ovulation is the process in the menstrual cycle by which a mature ovarian follicle ruptures and discharges an ovum that participates in reproduction. Ovulation also occurs in the estrous cycle of other female mammals, wh...

Ovary

...leased from one ovary . ... Get information on ovarian cancer symptoms, diagnosis, tests, staging, rese...is about the size of an almond. ... Learn about ovarian cysts symptoms including pelvic or abdominal pain. ... What is the ovary and what are ovarian cysts? What causes...

Minisatellite

... HRAS Minisatellite Alleles and Cancer Susceptibility. HRAS Mutations in Bladder Cancer ... JN, et al. The HRAS1 minisatellite locus and risk of ovarian cancer. ... This provides evidence that minisatellite conversion and crossover arise by a ... MS31 (D7S21) is a highly variable minisatellit...

Mature ovum

...ary. ... the woman will next release a mature ovum is estimated on ... Definition of matured in the Financial Dictionary - by Free ... Mature ovarian Teratoma Containing Malignant Elements. Mature ovum . Mature ovum . Mature ovum ... ovum usage examples. Usage example using the word ...
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