Ovarian

BRCA1 causes ovarian cancer through indirect, biochemical route

Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical signals one ovarian cell sends to another, according to a team of researchers led by scientists at the USC/Norris Comprehensive Cancer Center and the Keck School of Medicine of the University of Southern California. Their work is being published in the March 29 issue of the journal Current Biology.</p...

Human Eggs Can Develop From Ovarian Surface Cells In Vitro

Research has shown for the first time that human eggs may develop directly from cultured ovarian surface epithelium (OSE) cells derived from adult human ovaries. Oocytes derived from the culture of OSE cells developed in vitro into mature eggs suitable for fertilization and development into an embryo. These findings, published today in the Open Access journal Reproductive Biology and Endocrinolog...

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

A newly identified gene expression profile could help predict how patients with advanced ovarian cancer will respond to chemotherapy treatment. Described in a study in the November 1, 2005 issue of The Journal of Clinical Oncology (JCO), the new findings further establish an important role for microarray gene profiling as a predictor of clinical outcome in ovarian cancer, and could eventually pro...

Mass. General study finds potential ovarian cancer stem cells

Massachusetts General Hospital (MGH) researchers have identified potential ovarian cancer stem cells, which may be behind the difficulty of treating these tumors with standard chemotherapy. Understanding more about the stem-like characteristics of these cells could lead to new approaches to treating ovarian cancer, which kills more than 16,000 U.S. women annually and is their fifth most common c...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

A molecular "off" switch packaged in a tiny sphere penetrates deeply into ovarian cancer tumor cells, stifling a troublesome protein and drastically reducing the size of tumors, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 15 edition of Clinical Cancer Research. The mouse model experiment, featured on the cover of the journal, demonstrates a poten...

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NeoClone gets $750K for ovarian cancer detection

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Ovarian cancer in relationship with Hormone therapy

A major US study has found that women who have taken postmenopausal oestrogens for ten years or more are at substantially greater risk of fatal ovarian cancer. The risk persists for many years after therapy is discontinued, researchers from the American Cancer Society report// in the Journal of the American Medical Association.The study followed 201,681 postmenopausal women from 1982 t...

Progestin protects against ovarian cancer

Ovarian cancer is the most common cancer among women. It accounts for about 4 percent of all cancers in women, with more than 23,000 new cases diagnosed in 2001. Progestin is the ingredient in oral contraceptive pills that provides the highest// level of protection against ovarian cancer. Analysis by the Duke Comprehensive Cancer Center of a 20-year-old study showed that the pill can help prevent...

Inherited gene important in ovarian cancer

A gene causes significant complications in ovarian cancer. A gene implicated in inherited ovarian cancer is more significant in the disease than previously realised. Up to 10 per cent of cases of ovarian cancer arise from a mutation in a gene called BRCA1.// In these cases, the woman usually has a strong family history of the disease. We know that BRCA1 prevents tumours from developing, although...

Blood test may identify ovarian cancer

Some 23,300 American women are expected to be diagnosed with ovarian cancer every year, and the disease is expected to cause 13,900 deaths. It accounts for 4 percent of all cancers among women. A simple blood test may be able to identify ovarian cancer at its earliest stage. Currently, around three-quarters of women with ovarian cancer are diagnosed in advanced stages of the disease, when they ha...

Exercise lowers Risk of Ovarian Cancer

Research says that women have yet another good reason to exercise regularly. We know that regular exercise is good for so many things. It reduces our risk of heart disease and stroke,// and it even reduces our stress levels. Now a new study says it's also good for reducing our risk of ovarian cancer. Right now screening tests for ovarian cancer are not very appropriate. That makes it...

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Ovarian Antibodies

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
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Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial

LONDON, 12 July 2007 - Cancer drug developer Antisoma plc(LSE: ASM, US OTC: ATSMY) today announces new data from its phaseII trial of ASA404 in recurrent, platinum-sensitive ovarian cancer.This trial compares patients receiving ASA404 plus chemotherapy(n=37) with patients receiving chemotherapy alone (n=38). The mainfindings are as follows: * There was no advantage in median time t...

Novelos Therapeutics Announces Encouraging Results in Ongoing Phase 2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care

NEWTON, Mass.--(BUSINESS WIRE)--Jun 18, 2007 - NovelosTherapeutics, Inc. (OTCBB: NVLT), a biopharmaceutical companyfocused on the development of therapeutics to treat cancer andhepatitis, today announced encouraging results in an ongoingDana-Farber/Partners Cancer Care (DF/PCC) Phase 2 trial of NOV-002in combination with carboplatin in platinum-resistant ovariancancer patients. To date, 10...

GSK'S Pazopanib Shows Positive Results in Patients with Advanced Renal Cell Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

CHICAGO, June 04, 2007 /PRNewswire/ -- GlaxoSmithKline todayannounced results from ongoing Phase II studies of pazopanib inadvanced or metastatic renal cell carcinoma (RCC), ovarian cancerand soft tissue sarcoma (STS). These trials were presented at the43rd Annual Meeting of the American Society of Clinical Oncology(ASCO) in Chicago. The results observed in these trials withpazopanib sup...

Kosan Presents Promising Phase 1 Data on Second-Generation Hsp90 Inhibitor, Alvespimycin, Showing Antitumor Activity in Refractory Breast and Ovarian Cancers at ASCO

Clinical Benefit Shown in 35% of HER2-Positive Metastatic BreastCancer Patients HAYWARD, Calif., June 04, 2007 /PRNewswire-FirstCall/ -- KosanBiosciences Incorporated presented data from a Phase 1 clinicaltrial showing that alvespimycin, its second-generation Hsp90inhibitor, demonstrated promising antitumor activity andtolerability in combination with trastuzumab (Herceptin(R)) inpatient...

Expression Genetics, Inc. Announces Successful Completion of Phase I Trial of Gene-Based IL-12 for Treatment of Ovarian Cancer

HUNTSVILLE, Ala., April 16, 2007 /PRNewswire/ -- ExpressionGenetics, Inc., announced today the completion of a Phase Iclinical study evaluating the Company's lead drug candidate,EGEN-001. The study, conducted at The University of Alabama atBirmingham and , evaluated the safety, tolerance, preliminaryefficacy, and biological activity of the EGEN-001 in 13 patientswith advanced recurrent e...

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Ovarian cysts

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Ovarian Cancer

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Ovarian hypofunction

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