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Osmotic in Medical News

FDA Approves SAMSCA(TM) (tolvaptan), the First and Only Oral Vasopressin Antagonist to Treat Patients With Clinically Significant Hypervolemic and Euvolemic Hyponatremia

...increase greater than 12 mEq/L/24 hours) can cause osmotic demyelination syndrome (ODS), resulting in dysarth...e of the patients in these studies had evidence of osmotic demyelination syndrome or related neurological seq...increase greater than 12 mEq/L/24 hours) can cause osmotic demyelination resulting in dysarthria, mutism, dys...

Neuromed Announces Exalgo(TM) (hydromorphone HCl) Extended-Release Tablets (CII) Meets Primary Efficacy Endpoint in Pivotal Phase 3 Trial

...ble in the U.S. are immediate release formulations, requiring dosing several times per day. Exalgo, if approved, will employ the OROS(R) PUSH-PULL(TM) osmotic delivery system designed to release hydromorphone at a controlled rate over an extended period of time. An identical formulation, under the trade name...

Medical Futures partners with Norgine for MOVIPREP(R) in Canada

...lable in North America. PROFERRIN(TM): A unique heme iron supplement that has higher absorption and lower side effects. PEGALAX(TM): osmotic laxative with electrolytes for the treatment of chronic constipation. SANVAR(R): somatostatin analogue for the treatment of esophageal varice...

Neuromed Completes Enrollment for Phase 3 Chronic Low Back Pain Clinical Trial of NMED-1077

...tions of hydromorphone marketed in the U.S. are immediate release, requiring dosing several times per day. NMED-1077 employs the OROS(R) PUSH-PULL(TM) osmotic delivery system to release hydromorphone at a controlled rate over an extended period. OROS(R) Hydromorphone has been approved in Germany and other Eu...

Sugar's Healing Powers

... to exert an antibacterial effect by lowering water activity; the desloughing and debridement that is achieved with the paste is in part related to an osmotic effect on necrotic tissue and in part to mechanical cleaning." From the Annals of the Royal College of Surgeons of England, Vol. 78, 1996, p. 82-85:...

How does sodium phosphate combined with bisacodyl affect small intestine?

...H, Sulzbach, Germany) as a preparation before CE. Sodium phosphate solution is poorly absorbable and impedes water absorption from the gut through the osmotic gradient. Bisacodyl changes the net absorption of sodium and water in the small bowel into a net secretion and accelerates small intestinal transit. ...
Osmotic in Medical Technology

Intarcia Therapeutics, Inc. Announces Completion of Enrollment of ITCA 650 Phase 1b Study for the Treatment of Type 2 Diabetes

... exclusive worldwide license to the DUROS delivery technology. The DUROS delivery technology consists of the DUROS device, a matchstick-size miniature osmotic pump that is inserted subcutaneously to provide continuous and consistent drug therapy, and proprietary formulation technology that maintains stabilit...

Baxter Initiates Phase III Trial for the Treatment of Alzheimer's Disease

...anaphylactic reaction. Immune Globulin Intravenous (Human) products have been reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, and death. Patients predisposed to acute renal failure include patients with any degree of pre-existing renal insufficiency, diabetes melli...

Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimer's Disease Announced

...been reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, and death. Patients predisposed to acute renal failure include p...been reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, and death. Patients predisposed to acute renal failure include p...

Baxter Presents Latest Clinical Trial Results of GAMMAGARD LIQUID Administered Subcutaneously

...anaphylactic reaction. Immune Globulin Intravenous (Human) products have been reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, and death. Patients predisposed to acute renal failure include patients with any degree of pre-existing renal insufficiency, diabetes melli...

Baxter and The Alzheimer's Disease Cooperative Study Group to Pursue a Phase III Study of Gammagard Liquid in Patients With Alzheimer's Disease

...een reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, and death. Patients predisposed to acute renal failure include ...een reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, and death. Patients predisposed to acute renal failure include ...

Aeolus Pharmaceuticals Announces Successful Completion of Multiple Dose Safety Study of AEOL 10150

... Subjects in the third cohort received a daily dose of 2 mg/kg delivered by osmotic infusion pump over 24 hours for 6.5 days. The safety results can be summa... subjects. The continuous delivery of compound by weight adjusted dosing by osmotic infusion pump appears to be an option for subsequent trials and will requir...
Osmotic in Medical Products

Model 4420 Colloid Osmometer

Description:... Model 4420 Colloid Osmometer. Rapid measurement of colloid osmotic (oncotic) pressure for the prediction of edema onset in clinical situations... simulate the role of the natural vascular membrane in the establishment of osmotic pressure responsible for water flow between interstitial fluid and blood....
Company:Wescor, Inc.

Handbook on Injectable Drugs, 13th Ed.

Features:..., and repackaging information Key product data including common sizes, strengths, volumes, and forms in which the drug is supplied. Also includes pH, osmotic value, and other important product information ...
Company:Skyscape, Inc.

Puros Allografts

Features:...peroxide (H2O2) wash. Destroys remaining proteins in the graft, minimizing the risk of graft rejection. Inactives any remaining viruses exposed during osmotic bath....
Company:Zimmer, Inc.
Osmotic in Medical Dictionary

Osmolality

... day to day. ... osmolality ( ′äzmə′lalədē ) ( chemistry ) The molality of an ideal solution of a nondissociating substance that exerts the same osmotic pressure as Serum osmolality is controlled partly by a hormone called antidiuretic hormone (ADH) ... When serum osmolality increases, AD...

Intracellular

...lar adj. Occurring or situated within a cell or cells: intracellular fluid. ... the main intracellular ion that maintains intracellular fluid osmotic ... Vacuole - Plays a role in intracellular digestion and the release of cellular waste products. ... the movement of intracellular organe...

Hypothalamus

...rview of the Hypothalamus . Afferent and Efferent Connections ... Functions of the Hypothalamus . Temperature Control and Its Dysfunction. Water and osmotic Balance ... The hypothalamus is the main neural control center (brain part that controls endocrine glands). The pituitary gland lies just be...

Albumin

... English dictionary and encyclopedia. ... lactalbumin - albumin occurring in milk ... Albumin makes a large contribution to plasma colloid osmotic pressure due to its ... Albumin is measured by its ability to bind to bromcresol green. ... Albumin is given directly into a vein (intraveno...
Osmotic in Biological News

Artificial cells, simple model for complex structure

...lic pathways occur more rapidly because the chemicals necessary for the next step would be located nearby. The application of heat, or a change in osmotic pressure can cause the separated materials to mix. However, upon cooling or reversion to the initial pressure, the materials again separate. "It s...

Microbot motors fit to swim human arteries

...d the automotive industry. Responses to this need have been just as diverse, with designs developed using electromagnetic, electrostatic, thermal and osmotic driving forces. Piezoelectric designs however have favourable scaling characteristics and, in general, are simple designs, which have provided an exc...

News tips from the Journal of Neuroscience

...prevent neurodegeneration, Thompson and Brenowitz infused caspase inhibitors unilaterally into HVC, a song nucleus of white-crowned sparrows, using an osmotic pump mounted in a backpack. HVC volume, soma size, and neuron number were greater in the infused nucleus than in the contralateral nucleus after testo...

Drought tolerance in potatoes

...ponsive genes are conserved across plant taxa, especially genes involved in osmotic adjustment, detoxification, and cell communication and signaling. Schaflei...and cell defense functions. Solute concentrations were increased, lowering osmotic potential, to induce uptake of water from drying soils. Increased expressi...

MIT applies engineering approach to studying biological pathways

...s. The pathway is activated when yeast cells are exposed to a change in the osmotic pressure of their environment, for example, when salt is added to their gro...e cell balances the extra salt outside the cell so water is no longer under osmotic pressure to leave the cell. In the short term, glycerol concentration is...

American scientist's research of life's first cells

...the RNA and the vesicle's membrane led to the emergence of certain basic cellular behaviors. For example, when the genome replicates inside a vesicle, osmotic pressure leads the vesicle to "steal" membrane from other, empty vesicles. This could be an example of Darwinian evolution, according to Chen. "Explor...
Osmotic in Biological Technology

$10,000 ISSAC Award for Innovation Presented to MIT PhD

... and rapidly expanding area of life-saving and life-enhancing technology. The award-winning device is designed to function like a pump, using osmotic pressure to release drugs into the bladder. The size of the device, which is made with silicone and nickel alloy wire, is about that of a paper clip a...

Intarcia Therapeutics, Inc. Presents ITCA 650 Phase 1b Study Results as a Late-Breaker at the American Diabetes Association 69th Scientific Sessions

...e 2 diabetes consists of DUROS continuous delivery of exenatide. The DUROS delivery technology comprises the DUROS device, a matchstick-size miniature osmotic pump that is inserted subcutaneously to provide continuous and consistent drug therapy, and proprietary formulation technology that maintains stabilit...

Intarcia Therapeutics, Inc. Announces Acceptance of ITCA 650 Phase 1b Study for Late-Breaker Presentation at the American Diabetes Association 69th Scientific Sessions

...e 2 diabetes consists of DUROS continuous delivery of exenatide. The DUROS delivery technology comprises the DUROS device, a matchstick-size miniature osmotic pump that is inserted subcutaneously to provide continuous and consistent drug therapy, and proprietary formulation technology that maintains stabilit...

Phase III Trial Begins for GAMMAGARD LIQUID Plus rHuPH20 in Primary Immunodeficiency Patients

...ylactic reaction. Immune Globulin Intravenous (Human) products have been reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, and death. Patients predisposed to acute renal failure include patients with any degree of pre-existing renal insufficiency, diabetes melli...

Penn researchers demonstrate a flexible, 1-step assembly of nanoscale structures

...n pillars spaced 2 μm apart on a square lattice. When exposed to the organic solvent toluene, PDMS gels swell by as much as 130 percent. As the osmotic pressure builds, the circular pores in the PDMS deform and eventually snap shut to relieve the stress, much as the joints in railways and bridges expa...

Study Suggests GAMMAGARD LIQUID May Target the Primary Pathway Involved in Alzheimer's Disease

...anaphylactic reaction. Immune Globulin Intravenous (Human) products have been reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, and death. Patients predisposed to acute renal failure include patients with any degree of pre-existing renal insufficiency, diabetes melli...
Osmotic in Biological Products

Tyrode's Salts from Sigma-Aldrich

Description:...o produce fully defined media, salt solutions still play an important role in tissue culture. A salt solution's basic function, to maintain the pH and osmotic balance in the medium and to provide the cells with water and essential inorganic ions, is as valuable today as when it was first developed a century ...
Company:Sigma-Aldrich

Dulbecco's Phosphate Buffered Saline (DPBS) from Sigma-Aldrich

Description:...nd can be divided into four principal functions: serves as an irrigating, transporting and diluting fluid while maintaining intra- and extracellular osmotic balance; provides cells with water and certain bulk inorganic ions essential for normal cell metabolism; combined with a carbohydrate, such as glu...
Company:Sigma-Aldrich
Osmotic in Biological Definition

Cytosol

...s the concentration of soluble molecules increases within the cytosol, an osmotic gradient builds up toward the outside of the cell. Water flows into the cel..., the tonoplast or the cell wall (if present), are used to counteract the osmotic pressure. Details The cytosol is 20% to 30% protein . Normal huma...

Diabetes mellitus

...esent with frank poorly controlled diabetes. Thirst develops because of osmotic effects — sufficiently high glucose (above the ' renal threshold ') ...n concomitant loss of water, causing an increase in blood osmolality . The osmotic effect of high glucose levels combined with the loss of water will eventual...

Dialysis

...also called dialysis solution), a solution comprised of a known amount of a glucose dissolved in water. The strength of this solution determines the osmotic gradient, and therefore the amount of water that diffuses out of the bloodstream. Common strengths of glucose are 0.5%, 1.5%, 2.5% and 4.25%. 1.5% is...

Diffusion

...l ventilation NaKATPase Nervous system Neurotransmitter Nitric oxide Nobel Prize in Physiology or Medicine Osmosis osmotic Quorum sensing Respiration Reverse osmosis Second messenger Semipermeable membrane SI derived unit Sintering ...

Eukaryote

...ormones are often produced in vesicles. In higher plants, most of a cell's volume is taken up by a central vacuole or tonoplast, which maintains its osmotic pressure. Mitochondria and plastids Mitochondria are organelles found in nearly all eukaryotes. They are surrounded by double membranes, t...

Kidney

...enle who described it in the early 1860s. The loop of Henle maintains an osmotic gradient set up as a countercurrent exchange to filter and concentrate g...sodium ion absorption in the convoluted tubule. Any rise or drop in blood osmotic pressure due to a lack or excess of water is detected by the hypothalamus ...
Osmotic in Biological Dictionary

Vessel cell

...10, 2003 ... stem cell clone" found in adult bone marrow regenerated blood vessels and ... Water tends to move into the cell because of the osmotic effect of the low ... Many individual cells can form a vessel that can be several centimeters long. ... ...

Turgor

...eria cells, determined by the water content of the vacuole, resulting from osmotic pressure, i.e. the hydrostatic pressure produced by a solution in a... S...Biology-Online.org dictionary. ... Related terms: turgor pressure. ... osmotic pressure is the pressure that must be applied to a ... It is the resulting ...

Proton-motive force

...ae of higher plants. Coupling of ... BioInfoBank Library :: Proton - Motive Force :: physiology :: On the estimation of proton gradient and osmotic volume in chloroplast membranes. Membrane potential ... What does PMF stand for? Definition of Proton motive force in the list of acronyms ...

Osmoregulation

... Osmoregulation is the active regulation of the osmotic pressure of an organism's fluids to maintain the homeostasis of the o...ain water by ... osmoregulation n. Maintenance of an optimal, constant osmotic pressure in the body of a living organism ... Blood sugar · Osmoregulation...

Lysis

... contents to spill out, often by viral, enzymic or osmotic mechanisms that compromise its integrity. A fluid containing the contents of... Cytolysis, or osmotic lysis , occurs when a cell bursts due to an osmotic imbalance that has caused excess water to move int...

Excretion

...itrogenous by-products of metabolism. Through excretion organisms control osmotic pressure—the balance between inorganic ions and water—and maintain acid-bas...milk, although not important to the mother, ... Nitrogen Excretion and osmotic Regulation ... first, a process technically known as excretion . Excretio...
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