Orphan

Tolera Therapeutics Granted Orphan Drug Designation for Organ Transplant Rejection Drug

KALAMAZOO, Mich., April 9 /PRNewswire/ -- Tolera Therapeutics, Inc., was granted orphan drug status by the United States Food and Drug Administration (FDA) for its initial lead candidate, TOL101, for prophylaxis of acute rejection of solid organ transplantation. TOL101 is a biologic protein that...

Frost & Sullivan to Host Analyst Briefing on the European Orphan Diseases Market: Niche-Busters - An Attractive Future?

LONDON, Jan. 26 /PRNewswire/ -- The Healthcare Group at Frost & Sullivan is pleased to announce its 2009 Quarterly Analyst Briefing Presentation on the European Orphan Diseases Market to be held on Thursday, 5 February, 2009 at 2 p.m. GMT. (Logo: http://www.newscom.com/cgi-bin/prnh/200...

Insmed and Premacure Announce European Orphan Designation for IPLEX(TM) in Retinopathy of Prematurity in Infants

RICHMOND, Va., Jan. 21 /PRNewswire-FirstCall/ -- Insmed Inc. (Nasdaq: INSM ), a developer of follow-on biologics and biopharmaceuticals, and Premacure AB, a biopharmaceutical company dedicated to the development of, diagnosis and prevention of complications in neonates due to premature birth, t...

Ikaria(R) Acquires North American Rights to LUCASSIN(R) From Orphan Therapeutics

- No Currently Approved Drugs to Treat Hepatorenal Syndrome Type 1 in U.S. - CLINTON, N.J. and LEBANON, N.J., Sept. 2 /PRNewswire/ -- Ikaria Holdings, Inc. and Orphan Therapeutics, LLC announced today that they have entered into an agreement under which Ikaria ...

Latona Announces the Acquistion of Patent Rights and Orphan Drug Status to Novel Late Stage Drug Compound for Juvenile and Adult Rheumatoid Arthritis

PHOENIX, April 24 /PRNewswire/ -- Latona Life Sciences Inc. (Latona) announced today that it has entered into two agreements for the acquisition of patent rights and orphan drug status to a novel late-stage drug, trademarked "Oralgam," for the treatment of Juvenile and Adult Rheumatoid Arthrit...

Biotest Pharmaceuticals Corporation Responds to Orphan Drug Act Announcement

BOCA RATON, Fla., March 27 /PRNewswire/ -- Biotest Pharmaceuticals Corporation, a leading developer of immunology biotherapeutic products, today responded to an announcement that a Hepatitis B Immune Globulin Intravenous (Human) product manufactured by another company has received Orphan Drug ...

Ocera Therapeutics Receives Orphan Drug Status for AST-120 for Pouchitis

Company to Present at 26th Annual JP Morgan Healthcare Conference SAN DIEGO, Jan. 7 /PRNewswire/ -- Ocera Therapeutics, Inc., a privately-held biopharmaceutical company focused on the development and commercialization of proprietary compounds to treat gastrointestinal and liver diseases, an...

Isis Announces ISIS 333611 Granted Orphan Drug Status for Treatment of ALS

CARLSBAD, Calif., Dec. 13 /PRNewswire-FirstCall/ -- Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ) announced today that the U.S. Food and Drug Administration (FDA) has granted orphan drug status to ISIS 333611 for the treatment of an inherited form of amyotrophic lateral sclerosis (ALS), commonly...

ViroPharma Receives European Orphan Drug Designation for CAMVIA(TM)

EXTON, Pa., Nov. 12 /PRNewswire-FirstCall/ -- ViroPharma Incorporated (Nasdaq: VPHM ) today announced that the Committee for Orphan Medicinal Products (COMP) of the European Medicines Agency (EMEA) has granted orphan drug designation for CAMVIA for the prevention of cytomegalovirus (CMV) dise...

FDA Grants Kiadis Pharma Lead Product ATIR Orphan Drug Designation

AMSTERDAM, The Netherlands, Nov. 6 /PRNewswire/ -- Kiadis Pharma announced today that its lead product ATIR has been granted orphan drug designation by the US Food and Drug Administration (FDA) as a therapy for immune reconstitution and prevention of Graft versus Host Disease (GvHD) following ...

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Orphan in Medical Technology

Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Receives Orphan Drug Designation From EMEA

THE WOODLANDS, Texas, July 21 /PRNewswire-FirstCall/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX ), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, announced today that it has received orphan d...

Cystic Fibrosis - Liposomal Tobramycin Receives Second Orphan Drug Designation Within Weeks

ZURICH, July 16 /PRNewswire/ -- An innovative treatment for infections of the respiratory tract in cystic fibrosis patients has received a second orphan drug designation in the US only weeks after a first designation was granted. The recent designation relates to Burkholderia cepacia pathogens...

PARI Pharma Reports Successful Phase Ib Clinical Results for Inhaled Liposomal Cyclosporine A and Gains FDA Orphan Drug Designation for the Prevention and Treatment of Bronchiolitis Obliterans

MONTEREY, Calif., June 2 /PRNewswire/ -- This month's Journal of Aerosol Medicine and Pulmonary Drug Delivery features positive Phase Ib clinical trial results for PARI Pharma's L-CsA, inhaled liposomal cyclosporine A. In May, PARI Pharma received Orphan Drug Designation from the Food and Drug Ad...

NeurogesX Receives FDA Orphan Drug Designation for Qutenza(TM) for Treatment of Postherpetic Neuralgia

Potential Seven Years Market Exclusivity in PHN Pending Product Approval SAN MATEO, Calif., June 2 /PRNewswire-FirstCall/ -- NeurogesX, Inc. (Nasdaq: NGSX ), a biopharmaceutical company focused on developing and commercializing novel pain management therapies, announced today that the Offic...

AIMSPRO is Awarded TGA Orphan Status for the Treatment of Amyotrophic Lateral Sclerosis

LONDON, June 1 /PRNewswire/ -- Privately owned UK biotech company Daval International Limited ( http://www.davalinternational.com ) has been informed by Australia's Therapeutic Goods Administration (TGA) that its innovative anti-inflammatory agent AIMSPRO(R) has been awarded Orphan Status for ...

AMT Receives EMEA Orphan Drug Designation for Acute Intermittent Porphyria

AMSTERDAM, May 28 /PRNewswire-FirstCall/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, announced today that the European Medicines Agency has granted Orphan Drug Designation to AMT's gene therapy product AMT-021 for the treatment of acute int...

Hyperion Therapeutics Receives Orphan Drug Designation for HPN-100 for the Treatment of Urea Cycle Disorders

- Company preparing to initiate phase III clinical trial - SOUTH SAN FRANCISCO, Calif. , May 5 /PRNewswire/ -- Hyperion Therapeutics, Inc. today announced that HPN-100 has received orphan product designation from the U.S. Food and Drug Administration for maintenance treatment of patients wit...

Cystic Fibrosis - Orphan Drug Designation for Innovative Treatment Against Lung Infections by Axentis Pharma AG

ZURICH, Switzerland, April 30 /PRNewswire/ -- An innovative treatment for infections of the respiratory tract in cystic fibrosis patients has received orphan drug designation in the US. Axentis Pharma of Zurich, Switzerland announced today that this sought-after designation has been granted to...

Oasmia: FDA Grants Paclical(R) Orphan Drug Designation for Ovarian Cancer in the USA

UPPSALA, Sweden, April 14 /PRNewswire-FirstCall/ -- Oasmia Pharmaceutical, Uppsala, Sweden, has been granted Orphan Drug designation by the USA FDA of Paclical(R) for the treatment of ovarian cancer. Orphan Drug designation can entail additional assistance from FDA to expedite and optimize dru...

Kiadis Pharma Receives Two Orphan Drug Designations for Reviroc(TM) From the FDA

AMSTERDAM, December 8 /PRNewswire/ -- Biopharmaceutical company Kiadis Pharma announces today that the U.S. Food and Drug Administration (FDA) has granted its product Reviroc(TM) Orphan Drug Designations (ODD) for the treatment of two types of Non-Hodgkin Lymphoma (NHL). One ODD has been granted f...

Orphan in Medical Products

A to Z Drug Facts

Description:... Containing more than 600 full drug monographs, plus abbreviated monographs for combination drugs, orphan drugs and AIDS drugs in development, A to Z Drug Facts provides up-to-date information on more than 5,000 drugs....
Company:Skyscape, Inc.

A to Z Drug Facts, 6th Edition

Features:... Rx, OTC, orphan, and investigational drugs A searchable index of Canadian drugs by Trade name Indications for labeled, unlabeled and orphan uses Side effects organized by body system Route/Dosage section organized by age, route and specific disease state or medical condition Precautions...
Company:Mobipocket.com

Orphan in Medical Dictionary

Toxocariasis

...caused by larvae of Toxocara canis (dog roundworm) and less ... National Organization for Rare Disorders is dedicated to helping people with rare, orphan diseases. Rarediseases. ... Toxocariasis is not limited to pet owners. ... Toxocariasis ... Toxocariasis is an infectious disease caused b...

Respect

...aOmer, the "Counting of ... How to Earn Your Wife's Respect . How to Respect Wildlife while Camping ... ... who has no parents; Verily he is an orphan who is deprived of knowledge and adab ( respect /etiquette) ... Respect for the distinguishing signs of Allah Ta'ala ... ...

Incontinentia Pigmenti

..... Incontinentia Pigmenti International Foundation ... Incontinentia Pigmenti is a genetic disease, rare and not well known, called an " orphan " desease. ... Welcome to Incontinentia Pigmenti France ... Overview: Incontinentia pigmenti (IP) is an X-linked dominant neurocutaneous ....

Elephantiasis

... to filaria is spread by the agency of mosquitoes, in whose ... National Organization for Rare Disorders is dedicated to helping people with rare, orphan diseases. Rarediseases.org ... Elephantiasis is a condition ... Elephantiasis is caused by obstruction of the lymphatic system, which ... Ele...

Cystinuria

...ed by excessive levels of an amino acid called cystine in ... National Organization for Rare Disorders is dedicated to helping people with rare, orphan diseases. ... Four subtypes of Cystinuria are recognized. ... ...

Adoption

...e. Facilitating in the adoption process for needy and minority children across the United States. Our international adoption agency places orphan children with forever families. ... CWA offers adoption programs in Bulgaria, China, Ethiopia, Guatemala, Kazakhstan, ... Nonprofit, nation-wide...

Orphan in Biological News

Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants

CLINTON, N.J., July 28 /PRNewswire/ -- Ikaria Holdings, Inc., a fully integrated critical care biotherapeutics company, announced today that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for inhaled carbon monoxide for use in the reduction of the incidence and...

Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants

CLINTON, N.J., July 28 /PRNewswire/ -- Ikaria Holdings, Inc., a fully integrated critical care biotherapeutics company, announced today that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for inhaled carbon monoxide for use in the reduction of the incidence and...

Sequella receives US and EU orphan drug status for SQ109 for the treatment of TB

ROCKVILLE, MD -- Sequella, Inc., a clinical-stage biopharmaceutical company focused on commercializing products to treat diseases of epidemic potential, announced today that the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) independently reviewed Sequella lead dr...

Virulizin granted orphan drug status in Europe

Leading marine scientists for the first time have assessed dolphin and porpoise populations around the world which are severely threatened by entanglement in fishing gear and recommended nine urgent priorities for action in a report commissioned by the World Wildlife Fund. These nine projects highl...

DuoCort: New chronotherapy for adrenal insufficiency

...en. DuoCort is developing an improved glucocorticoid replacement therapy for patients with adrenal insufficiency, a rare disease for which DuoCort has orphan drug designations in Europe and the USA. The new product, a once daily dual-release hydrocortisone oral tablet that comes in both 5 mg and 20 mg sizes...

International collaboration by scientists culminates in novel ion channels database

...l and patho-physiological properties of human, rat and mouse genes encoding in excess of 354 non sensory G protein-coupled receptors (GPCRs) including orphan receptors, 71 LGIC and 141 VGIC subunits. This set of genes is known to encompass a third of current drug targets and a significant proportion of li...

Duke, Harvard researchers to monitor bonobo reintroduction

...are and threatened bonobo ape will lead monitoring efforts after a group of orphan bonobos are returned to the wild in the Congo for the first time this month. On June 14 and 28, for the first time ever, a group of 18 orphan bonobos will be returned to the wild. "We'll be monitoring the social be...

NIH announces new program to develop therapeutics for rare and neglected diseases

...esearch (ORDR). "While Congress has previously taken important steps to help these patients, such as providing incentives for drug companies under the orphan Drug Act, this is the first time it is providing support for specific preclinical research and product development known to be major barriers prevent...

Master gene plays key role in blood sugar levels

...dies in O'Malley's laboratory in collaboration with researchers from Duke University Medical Center in Durham, N.C., revealed that SRC-2 works with an orphan nuclear receptor ROR alpha to affect the activity of the sugar-converting enzyme, glucose-6-phosphatase in the liver. The liver produces 90 percen...

Avoiding Spleen Removal for Cooley's Anemia SufferersAvoiding spleen removal for Cooley's anemia suf

...progressive iron overload occurs from increased gastrointestinal iron absorption. Despite its prevalence, Cooley's anemia (beta-thalassemia) is an orphan disease, of which studies are rare and not well-funded. Current disease management includes prenatal diagnosis, transfusion therapy, iron chelation an...

Orphan in Biological Technology

DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD

PRINCETON, N.J., Aug. 4 /PRNewswire-FirstCall/ -- DOR BioPharma, Inc., (OTC Bulletin Board: DORB) (DOR or the Company), a late-stage biopharmaceutical company, announced today that the Office of Orphan Products Development of the United States Food and Drug Administration (FDA) has granted Or...

Micromet Receives European Orphan Drug Designation for Treatment of Acute Lymphoblastic Leukemia with BiTE Antibody Blinatumomab

BETHESDA, Md., Aug. 3 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI ), a biopharmaceutical company developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases, today announced that it has received Orphan Drug Designation from the Europ...

Berlin Heart Inc. Receives FDA Orphan Product Development Grant

THE WOODLANDS, Texas, June 17 /PRNewswire/ -- Berlin Heart Inc. today announced it has been awarded an Orphan Product Development Grant by the FDA, to support the ongoing Investigational Device Exemption (IDE) study of the EXCOR(R) Pediatric Ventricular Assist Device (VAD). Dr. Christopher Alm...

Delcath Systems Granted Third Orphan Drug Designation

NEW YORK, June 2 /PRNewswire-FirstCall/ -- Delcath Systems, Inc. (Nasdaq: DCTH ), a medical technology company testing its proprietary treatment method for primary and metastatic cancers to the liver, announced today that the United States Food and Drug Administration ("FDA") granted Delcath's a...

Tolera Therapeutics Granted Orphan Drug Designation for Organ Transplant Rejection Drug

KALAMAZOO, Mich., April 9 /PRNewswire/ -- Tolera Therapeutics, Inc., was granted orphan drug status by the United States Food and Drug Administration (FDA) for its initial lead candidate, TOL101, for prophylaxis of acute rejection of solid organ transplantation. TOL101 is a biologic protein that...

FDA Approves Orphan Drug Status for Revolutionary Cancer Drug for Children

LOS ANGELES, Oct. 20 /PRNewswire/ -- The Cure Our Children Foundation, a nonprofit charitable foundation dedicated to children, announced today that the U.S. Food and Drug Administration (FDA) has approved the Orphan Drug Designation of the foundation's unique drug product for children with Ew...

EMEA Grants Kiadis Pharma Lead Product ATIR(TM) Orphan Drug Designation

AMSTERDAM, September 22 /PRNewswire/ -- Kiadis Pharma announced today that its lead product ATIR(TM) has been granted orphan drug designation (ODD) by the European Medicines Agency (EMEA) for the prevention of acute Graft versus Host Disease (GvHD) following an allogeneic bone marrow transplan...

FDA Grants Epeius Biotechnologies' Rexin-G a Third Orphan Drug Designation, This Time for the Treatment of Soft Tissue Sarcomas

SAN MARINO, Calif., July 9 /PRNewswire/ -- Epeius Biotechnologies Corporation today announced that Rexin-G has been granted Orphan Drug Designation by the U.S. Food and Drug Administration (FDA) for the treatment of all soft tissue sarcomas. This latest approval is the third clinical indicatio...

Epeius Biotechnologies' Tumor-Targeted Rexin-G Receives FDA Orphan Drug Designation for the Treatment of Osteosarcoma

SAN MARINO, Calif., July 8 /PRNewswire/ -- Epeius Biotechnologies Corporation today announced that Rexin-G has been granted Orphan Drug Designation by the U.S. Food and Drug Administration (FDA) for the treatment of osteosarcoma. Based on several criteria, including the rarity, seriousness, an...

Raptor Pharmaceuticals Corp. Receives FDA Orphan Drug Designation for Cysteamine in Huntington's Disease

Potential Efficacy in Huntington's Disease Already Demonstrated NOVATO, Calif., June 9 /PRNewswire-FirstCall/ -- Raptor Pharmaceuticals Corp. ("Raptor" or the "Company") (OTC Bulletin Board: RPTP), today announced that the U.S. Food and Drug Administration ("FDA") has granted orphan drug d...

Orphan in Biological Dictionary

Intergenic DNA

...iseases, symptoms, treatments, and other medical and health issues. ... of DNA , Intergenic ... Eukaryotic intergenic DNA This article is an orphan , as few or no other articles link to it. ... the Wikipedia article "Eukaryotic intergenic DNA ". Read more ... Intergenic region summary with...

Hydrolysis

...compound by reaction with water, such as the dissociation of a dissolved salt or the catalytic conversion Hydrolysis constant This article is an orphan , as few or no other ... generalized form, the hydrolysis constant can be described ... base hydrolysis constant? ... Hydrolysis is a chemi...

Antisense

...e ESTs are depicted in white. ... Antisense custom design and synthesis for specific gene silencing, using superior results. ... Genta Obtains orphan Drug Designation for C-Myb Antisense ... We have evaluated the specificity and the variation in activity against human immunodeficiency viru...