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OKT3 - Wikipedia, the free encyclopedia

OKT3 is an immunosuppressant drug given to reduce acute rejection in transplant patients. A major milestone in the prevention of acute allograft rejection was achieved with the development of the mAb OKT3, the first mAb to be approved for clinical use in humans.

OKT3 definition - Medical Dictionary definitions of popular medical ...

Online Medical Dictionary and glossary with medical definitions ... OKT3 acts by blocking the function of T cells which play a major role in acute graft rejection. ...

OKT3 Tissue PI

with ORTHOCLONE OKT3 must be ... administration of any dose or course of ORTHOCLONE OKT3. ... OKT3 Sterile Solution is a homogeneous, reproducible antibody ...

OKT3: Heart Transplant Surgery Patient Guide

OKT3 may be used right after your transplant, if your kidneys are not ... OKT3 may be also used to treat moderate to severe rejection episodes ...

Anaphylactoid Reaction to Muromonab-CD3...: Discussion

Discussion: Muromonab-CD3 (OKT3), a murine IgG2a antibody directed against the T3 (CD3) complex on mature lymphocytes, triggers adverse immune reactions.

Immunosuppressive Therapies in Organ Transplantation: Muromonab CD-3 (OKT3)

Muromonab CD-3 (OKT3): Until tolerance, the success of organ transplantation will depend on skillful use of poweful immunosuppressive agents.
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