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OIC in Medical Technology

Nektar Announces Positive Results from Phase 2 Study of Oral NKTR-118 in Patients with Opioid-Induced Constipation (OIC)

...s were written for opioids in 2007 in the United States alone. Currently, there are no oral drugs approved that are indicated to treat OIC. OBD and oic can significantly impact quality of life and increase healthcare utilization. 1. Panchal SJ, Muller-Schwefe P, Wurzelmann JI. Opioid-induce...

New England Journal of Medicine Publishes Results From a RELISTOR Phase 3 Clinical Study

... The clinical study showed that significantly more oic patients with advanced illness experienced bowel m...nstrate that RELISTOR has the potential to relieve oic effectively, but that it does so without interferi...y and safety of subcutaneous RELISTOR in relieving oic in patients with an advanced illness. Co-primary e...

Wyeth and Progenics Announce Preliminary Clinical Trial Results for RELISTOR Oral and Intravenous Formulations

...dministration approved RELISTOR subcutaneous injection for the treatment of oic in patients with advanced illness who are receiving palliative care, when r...e bromide injection) for subcutaneous use is indicated for the treatment of oic in patients with advanced illness receiving palliative care. Applications a...

NKTR-118 Shows Substantial Oral Bioavailability and Extended Half-Life in Phase 1 Clinical Data Presented at American Pain Society Meeting

...OIC. Stool softeners or laxatives may be ineffective for many patients with oic and they are often associated with side effects like diarrhea and stomach cramps. OBD and oic can significantly impact quality of life and increase healthcare utilizatio...

Nektar Commences Phase 2 Trial of NKTR-118 (oral PEG-naloxol) Evaluating Efficacy and Safety as Treatment for Opioid-Induced Bowel Dysfunction

...re excited to begin our Phase 2 clinical trial for oral NKTR-118 in OBD and oic patient settings," said Hoyoung Huh, M.D., Ph.D. Chief Operating Officer an... OBD. Stool softeners or laxatives may be inadequate for many patients with oic and often are associated with unwanted side effects such as bloating and cr...

Progenics and Wyeth Announce Positive Results from Three-Month Clinical-Extension Study of Subcutaneous Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Advanced Illness

... Symposium in St. Gallen, Switzerland. Eighty-two oic patients completed a placebo-controlled phase 3 st...red as needed, for up to three months. Forty-two oic patients received subcutaneous methylnaltrexone pr...ioid receptor antagonist that is designed to treat oic without interfering with pain relief. Currently, t...
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