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Nucleotides in Medical News

Scientists Decode HIV Genome

...A rather than double-stranded DNA. Information encoded in RNA is more complex. The HIV RNA genome is huge, composed of two strands of almost 10,000 nucleotides each. Previously, scientists had managed to model only small regions of the HIV RNA genome. In this study, University of North Carolina at Chapel H...

Drug Might Restore Sense of Smell

...reviously discovered that people with hyposmia had reduced levels of cyclic nucleotides in their saliva and nasal mucous, and that treatment with theophylline had ...this growth factor and restored some of the sense of smell. These cyclic nucleotides are growth factors for olfactory (related to smell) and other neural tissue...

The GenoMEL project identifies a new region of the genome associated with the risk of melanoma

...nd Dr. Josep Malvehy are the only Spanish authors of this article. Single-nucleotide polymorphisms (SNPs) are small variations in the sequence of nucleotides that make up DNA and can be associated with many genetic diseases. The study published in Nature Genetics performs an exhaustive search for SNPs in ...

RNA snippet suppresses spread of aggressive breast cancer

...s laboratory, screened patient breast cancer samples for microRNAs with potential roles in metastasis. MicroRNAs are single strands of RNA about 21-23 nucleotides long. Within a cell, a single microRNA can fine-tune the expression of dozens of genes simultaneously. This capability could be particularly important...

Ovarian Cancer Breakthrough Heralds New Era of Treatment

...ity news release. In the study, researchers decoded four granulosa cell tumors using "next generation" sequencing machines that decode billions of nucleotides at rapid speed and new computer techniques to quickly assemble the data. While most types of cancer, including ovarian cancers, have a broad range ...

Abbott Annual Meeting Highlights Outstanding 2008 Results, Continued Strong Outlook

...(Abbott's proprietary niacin extended-release) and simvastatin. Similac Advance EarlyShield(TM), an infant formula with a blend of prebiotics, nucleotides and antioxidants to support a baby's natural immune system. It uses a new SimplePac(TM) package that has a one-hand grip, hinged lid and scoop in the...
Nucleotides in Medical Products

DyNA Quant™ 200 Fluorometer

Features:... Quantitates DNA selectively in the presence of protein, RNA and nucleotides with the Hoechst 33258 assay Measures DNA accurately from 10 ng/ml to 5 µg/ml, final assay concentration Detects down to 1 ng of DNA in 3 ...
Company:GE Healthcare
Nucleotides in Medical Dictionary

Smooth tongue

...h tongue of the aged] [Article in French] Rodesch P. Mesh Terms: ... Tongue Diseases*/etiology. Tongue Diseases*/pathology. Substances: Adenine nucleotides ... Tongue problems - Overview, Tongue problems include pain, swelling, or a change in how the tongue looks. ... Papillae are lost, causing ...

Proximal

...stic ... ... end, would be redirected to the 5'- proximal region of the template, guided by a ... the duplex, with a preference for 3'- proximal nucleotides within the body TRS. ... proximal . Definition from Wiktionary, a free dictionary. Jump to: navigation, search ... Retrieved from "http://en.wikt...

Adenoviruses

...es in Reptiles ... Adenoviruses and Yellow Fungus (ReptileRooms) Bearded Dragon Diseases (Yahoo!Groups Email List) ... Total genome 30000-42000 nucleotides long. ... two adenoviruses ... human adenoviruses . porcine adenovirus 3 ... ... human adenoviruses cause ... The role of adenoviruses in...
Nucleotides in Biological News

New tool isolates RNA within specific cells

... Health and HHMI. Cleary's group built its tool with the enzyme uracil phosphoribosyltransferase (UPRT), a nucleotide salvage enzyme that prepares nucleotides for incorporation into newly synthesized RNA. By altering the nucleotide analog 4-thiouracil, the UPRT enzyme caused RNA to become tagged with thioura...

Penn biologists discover how 'silent' mutations influence protein production

...orescent protein by as much as 250-fold, without changing the properties of the protein. Codon bias, the probability that one codon of three adjacent nucleotides will code for one amino acid over another, was previously thought to be the cause for protein expression variance, but it did not correlate with gene ...

New therapeutic strategy could target toxic protein in most patients with Huntington's disease

...s written with four letters, A, C, T, and G, which stand for the four nucleotides, adenosine, cytidine, thymidine, and guanosine. The pattern of these nucleotides dictates which protein is encoded by a given gene. DNA in the nucleus is transcribed as messenger RNA, which leaves the nucleus and begins making prot...

Malaria parasite zeroes in on molecule to enhance its survival, team finds

...ism takes up nutrients from the environment and converts them to energy and the molecular building blocks that cells use to grow. Amino acids, sugars, nucleotides and vitamins are all metabolites. To conduct the study, the team used a mass spectrometry-based method developed in the neighboring laboratory of J...

Study: Fluid buildup in lungs is part of the damage done by the flu

...ucing and replication machinery of the cell. Those nucleotides then bind to receptors of other cells in a series ...ver the lungs and cell surfaces, you release these nucleotides and generate fluid so you can cough up the bacteri... earlier research to block the generation of these nucleotides to prove the fluid clearance mechanism behind a di...

Tailor-made recombinant proteins in mammals

...se, into the nonstandard amino acid residue formylglycine. "Formyl" is another name for a simple aldehyde group. "So all we had to do was clone the nucleotides encoding those six residues from the sulfatase sequence into the DNA of the target protein we want to produce, at the site corresponding to where we w...
Nucleotides in Biological Technology

DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies

...can accurately model the large variety of modified nucleotides that are added to or replace DNA and RNA sequences...ining the unique features of kinetics and modified nucleotides with its existing OMP™ (Oligonucleotide Mode...mulate and design assays that incorporate modified nucleotides within the OMP™ program. Modifieds™ c...

New cow genome sequence released

...th independent genetic maps, and a more complete representation of cow genes, than alternative assemblies. The new assembly places some 150 million nucleotides (6%) more DNA sequence data onto chromosomes than the other draft assembly currently available, BosTau4.0 from the Baylor College of Medicine (BCM4). ...

Molecular sleuths track evolution through the ribosome

...970s, he and his colleagues found consistent differences in the sequence of nucleotides that spell out the RNA of the ribosome in bacteria and archaea. These "mole...e the assembly of new proteins. The researchers analyzed the sequence of nucleotides (the building blocks of RNA) and amino acids (the building blocks of protei...

Pacific Biosciences Raises $100 Million to Fund Commercial Product Development

...he field of DNA sequencing. The first is the SMRT(TM) chip, which enables observation of individual fluorophores against a dense background of labeled nucleotides by maintaining a high signal-to-noise ratio. The second are phospholinked nucleotides, which produce a completely natural DNA strand through fast, acc...

Pacific Biosciences Acquires Single Molecule Sequencing Technology from LI-COR Biosciences

...it has acquired "sequencing by incorporation" technology from LI-COR Biosciences of Lincoln Nebraska. Sequencing by incorporation generally identifies nucleotides in a DNA sequence based upon synthesis of a complementary DNA strand. The technology acquired from LI-COR broadens Pacific Biosciences' existing intel...

Microchip Biotechnologies, Inc. Collaborating With Stanford University on Developing a Front End Microfluidic-Based Sample Preparation System for Pyrosequencing Platforms

...den. Pyrosequencing relies on the bioluminometric real-time detection of inorganic pyrophosphate (PPi) that is released on successful incorporation of nucleotides during DNA synthesis. About Microchip Biotechnologies Microchip Biotechnologies Inc. is an early-stage privately-held company located in Dublin, C...
Nucleotides in Biological Products

QXL 520 C2 maleimide from AnaSpec

Description:...ns, the single isomers are increasingly preferred for labeling peptides and nucleotides because they give better resolution in HPLC purification that is often requ... labeling peptides and proteins. 6-TAMRA is predominately used for labeling nucleotides and sequencing nucleic acids. Minimum Purity: 95%. Abs (max): 547 nm; Em (m...
Company:AnaSpec

EDTA, 0.5 M solution from GE Healthcare, formerly Amersham Biosciences

Description:... EDTA, 0.5 M solution, 100 ml. Ethylene diaminetetraacetic acid.Sterile, nuclease-free. Category: nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Company:GE Healthcare, formerly Amersham Biosciences

X-Gal from GE Healthcare, formerly Amersham Biosciences

Description:...o-3-indolyl-b-d-galactoside.Histochemical substrate for b-galactosidase, used in blue/white screening.Store at -20 C. Protect from moisture. Category: nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Company:GE Healthcare, formerly Amersham Biosciences

3-O-Methylguanosine 5-Triphosphate, Sodium from GE Healthcare, formerly Amersham Biosciences

Description:... 3'-O-Methylguanosine 5'-Triphosphate, Sodium, 1 umol. Category: nucleotides & Enzymes & Biochemicals, Nucleotides, Additional Nucleotide Products....
Company:GE Healthcare, formerly Amersham Biosciences

EGTA from GE Healthcare, formerly Amersham Biosciences

Description:... EGTA, 10 g. Ethylene glycol-O,O-bis-[2-amino-ethyl]-N,N,N,N,-tetraacetic acid.Assay: > 99.0%. Category: nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Company:GE Healthcare, formerly Amersham Biosciences

EGTA from GE Healthcare, formerly Amersham Biosciences

Description:... EGTA, 50 g. Ethylene glycol-O,O-bis-[2-amino-ethyl]-N,N,N,N,-tetraacetic acid.Assay: > 99.0%. Category: nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Company:GE Healthcare, formerly Amersham Biosciences
Nucleotides in Biological Definition

Anticodon

... An anticodon is a unit made up of three nucleotides which play an important role in various DNA cycles, including RNA translation . It is, specifically, the group of nucleotides on a strand of tRNA that is complementary to specific codons on a stran...

Bioinformatics

...enome of dozens of organisms, within billions of nucleotides . These programs can compensate for mutations (ex...f thousands of small DNA fragments (each about 600 nucleotides long). The ends of these fragments overlap and, al...ulatory sequences within a genome. Not all of the nucleotides within a genome are genes. Within the genome of hi...

Biopolymer

...mino acid residues as they occur from the amino terminus to the carboxylic acid terminus. The convention for a nucleic acid sequence is to list the nucleotides as they occur from the 5' end to the 3' end of the polymer chain , where 5' and 3' refer to the numbering of carbons around the ribose ring which pa...

BLAST

...s similar to a subsequence in the database. In typical usage, the query sequence is much smaller than the database, e.g., the query may be 1 thousand nucleotides while the database is several billion nucleotides. To define what it means for two subsequences to be "similar", BLAST uses the Smith-Waterman algo...

Genetic code

...o acid; it is said to be two-fold degenerate if only two of four possible nucleotides at its third position specify the same amino acid. In two-fold degenerate codons, the equivalent third position nucleotides are always either two purines (A/G) or two pyrimidines (C/T). The dege...

Bioinformatics

...enome of dozens of organisms, within billions of nucleotides . These programs can compensate for mutations (ex...f thousands of small DNA fragments (each about 600 nucleotides long). The ends of these fragments overlap and, al...ulatory sequences within a genome. Not all of the nucleotides within a genome are genes. Within the genome of hi...
Nucleotides in Biological Dictionary

Wobble base pair

... In molecular biology, a wobble base pair is a non-Watson-Crick base pairing between two nucleotides in RNA molecules. The four main wobble base pairs are guanine-uracil, inosine-uracil, inosine-adenine, and inosine-cytosine . The thermodynamic st...

Uracil

...; Uracil News <== Genetics101 News ... The nucleotide derivatives of uracil perform important functions in cellular ... Since the uracil nucleotides contain only ribose and not deoxyribose, UTP is the ... ...

Transposon mapping

...oson maps that are used for DNA sequencing. ... Chromosome Mapping . DNA Transposable Elements. Software ... ... to a 466-bp region which spans nucleotides 15215 to 15681 on the transposon map . ... an intact chromosome-borne transposon Tn916 delta E. Cloned segments ... PLoS Genetics ... global ...

Transcription start site

...s ... from the transcription start site to just ... Transcription Factors Transcription factors are protein complexes that help RNA ... nucleotides upstream from the transcription start site (T is the nucleotide ... Transcription Binding Tools. Transcription Start Site Predict...

Termination codon

...nitions ... About Us | Privacy Policy | Site Map. August 5, 2009. home > termination codon definition ... A codon is a triplet of adjacent nucleotides in mRNA that ... from the AUG codon to the termination codon , establishes the protein that is to be synthesized. ... ... the ribosome enc...

Tandem repeat sequences

... terminal repeat , SINEs, LINEs) · Genomic island · Alu sequence ... A short tandem repeat (STR) in DNA occurs when a pattern of two or more nucleotides are repeated and the repeated sequences are directly adjacent to each other. The pattern can range in length from 2 to 10 base pairs (bp) n in a g...
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