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Nucleoli in Biological News

Researchers solve piece of large-scale gene silencing mystery

...f rRNA genes, they could potentially slow the growth rate of tumor cells and thereby slow the progression of diseases like cancer. In cancer cells, nucleoli are conspicuously large because of a dramatic increase in the transcription of rRNAs, which in turn leads to an increase in the production of ribosome...

Regulating the nuclear architecture of the cell

...es for ribosomal DNA were normally located in the heterochromatin, multiple nucleoli appeared in the nucleus. Mutations in another pathway, that of RNA in...rpen and Peng found that Drosophila with mutant dcr-2 genes showed multiple nucleoli and other symptoms of heterochromatin deregulation, just as Su(var)3-9 muta...
Nucleoli in Biological Technology

Cylene Pharmaceuticals Initiates Phase II Clinical Trial of Quarfloxin (CX-3543) in Patients With Carcinoid/Neuroendocrine Tumors

...ers arising from neural crest cells. "Quarfloxin (CX-3543) is a small molecule that disrupts a protein:rDNA complex that forms in the abnormal nucleoli of cancer cells, thereby selectively inducing apoptotic cell death in cancers," said Dr. William Rice, President and Chief Executive Officer of Cylene...
Nucleoli in Biological Definition

Cell nucleus

...(Drawing is based on ER images.) Inside the nucleus is one or several nucleoli surrounded by a fibrous matrix called the nucleoplasm . The nucleoplasm i...e regions of DNA that constitute heterochromatin vary between cell types. nucleoli are densely-stained structures at which ribosome subunits are assembled. ...

Nucleoplasm

...romosomes contain information encoded in DNA attached to proteins called histones and are usually arranged in to a dense network called chromatin. nucleoli are granular structures which make ribonucleic DNA (rDNA) and assemble it with proteins. ...

Meiosis

...omes, as well as the polar migration of centrioles , the dispersion of the nucleoli and nuclear envelope and the formation of the spindle fibres (including the...e compared to telophase I. In this prophase we see the disappearance of the nucleoli and the nuclear envelope again as well as the shortening and thickening of ...
Nucleoli in Biological Dictionary

Nucleoli

The nucleolus is a non-membrane bound structure composed of protein and nucleic acids found within the nucleus. The ribosomal RNA is transcribed within the nucleolus. The nucleolus ultrastructure can be visualized through an... Nucleoli appear sharply demarcated within the surrounding ...

Nucleolar organizer

...olar organizer region associated (Ag ... In recent years, nucleolar organizer region (NOR) scores have been explored for ... Silver-binding nucleoli and nucleolar organizer regions in FNAC of the breast. ... Nucleolar , organizer ,biological ,biology dictionary,biology terminology,biology ...
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(Date:10/18/2014)... a sample of patients with undiagnosed, suspected genetic conditions, ... with a higher molecular diagnostic yield than traditional molecular ... JAMA . The study is being released to coincide ... , Exome sequencing, which sequences the protein­coding region of ... material present in a cell or organism), has been ...
(Date:10/17/2014)... German . To ... treating overdoses, doctors are often limited to supportive therapy such ... a combination of drugs involved. So what can be done ... pills? ETH professor Jean-Christophe Leroux from the Institute of Pharmaceutical ... this question. "The task was to develop an agent that ...
(Date:10/16/2014)... thinking on how the bowel lining develops and, in ... cancer starts. , The researchers produced evidence that stem ... that are a feature of the bowel lining, and ... development, a controversial finding as scientists are still divided ... technologies, Dr Chin Wee Tan and Professor Tony Burgess ...
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