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Nonspecific in Medical News

Science Zeroes In on New Alzheimer's Drug Target

...ain the results of an earlier study, also by Tsai's group. It showed that a nonspecific HDAC inhibitor-type drug could improve cognitive function in a mouse model ...on that accompanies Alzheimer's disease, Tsai's group in 2007 found that a nonspecific HDAC inhibitor could restore learning ability and memory in the stricken mi...

Consumer Reports Survey Shows High Satisfaction for Physical Therapist Treatment of Back Pain

...tive disk disease. J Am Acad Orthop Surg. 2009; 17:102-111. 2) Macedo L, Maher C, Latimer J, McAuley J. Motor control exercise for persistent, nonspecific low back pain: A systematic review, Phys Ther . 2009; 89: 9-25. Physical therapists are highly-educated, licensed health care professionals who ...

Skin Woes Take Toll on U.S. Combat Troops

...of the study was that dermatitis, benign melanocytic nevus [noncancerous moles], malignant neoplasms [skin cancers], urticaria [hives], and a group of nonspecific diagnoses were the most common post-evacuation diagnoses in our study population," McGraw said. "These diagnoses are similar to the most common dermat...

3 clinical features identified to avoid misdiagnosis of TIAs

...eizures, for example symptoms take more than a minute to manifest themselves." The researchers found that a TIA was unlikely if a patient reported nonspecific symptoms, such as lightheadedness, tightness in the chest or stomach upset, along with the neurological dysfunction. A TIA was also unlikely if th...

Endoscopic ultrasound highly accurate in evaluating ambiguous radiographic findings of the pancreas

...ndoscopy (ASGE). Occasionally, patients who are asymptomatic or who have nonspecific symptoms, such as weight loss and abdominal pain, have subtle abnormal or i...P'' or "dilated PD" detected on a CT and/or MRI performed for evaluation of nonspecific symptoms, such as abdominal pain or weight loss. They also observed that an...

When Are Antibiotics for Lyme Disease Medically Necessary?

...ted patients may develop a bull's-eye rash. In the second stage, they may show multiple skin lesions that coincide with flu-like symptoms, followed by nonspecific muscular, skeletal, arthritic, neuralgic, psychiatric and even cardiac symptoms. "A diagnosis of Lyme disease should never be made based on initial ...
Nonspecific in Medical Technology

Appendicitis: Evolving Tools to Diagnose a Classic Disease

... Clinicians invariably order laboratory studies in cases of suspected appendicitis, where an elevated white blood cell count (WBC) is a classic but nonspecific feature. Only 80-85% of patients with appendicitis, however, have a WBC over 10K. A study with excellent sensitivity is serum C-reactive protein (CR...
Nonspecific in Medical Products

Esterase Stain, Nonspecific

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Anti-Thyroid Antibody (TA) Test Kit - Monkey Thyroid Substrate

Description:...t components include substrate slides, controls, conjugate, mounting medium, phosphate-buffered saline (PBS) and ZORBA-NS serum diluents to reduce the nonspecific fluorescence associated with some serum specimens....
Company:Inverness Medical Innovations

Autoantibody Screen (AAS) Test Kit - Rat Kidney/Stomach Substrate

Description:...t components include substrate slides, controls, conjugate, mounting medium, phosphate-buffered saline (PBS) and ZORBA-NS serum diluents to reduce the nonspecific fluorescence associated with some serum specimens....
Company:Inverness Medical Innovations

Anti-Nuclear Antibodies (ANA) Hep-2 Substrate

Description:...t components include substrate slides, controls, conjugate, mounting medium, phosphate-buffered saline (PBS) and ZORBA-NS serum diluents to reduce the nonspecific fluorescence associated with some serum specimens....
Company:Inverness Medical Innovations

Anti-Smooth Muscle Antibody (ASMA) Test Kit

Description:...t components include substrate slides, controls, conjugate, mounting medium, phosphate-buffered saline (PBS) and ZORBA-NS serum diluents to reduce the nonspecific fluorescence associated with some serum specimens....
Company:Inverness Medical Innovations

Anti-Mitochondrial Antibody (AMA) Test Kit

Description:...t components include substrate slides, controls, conjugate, mounting medium, phosphate-buffered saline (PBS) and ZORBA-NS serum diluents to reduce the nonspecific fluorescence associated with some serum specimens....
Company:Inverness Medical Innovations
Nonspecific in Medical Dictionary

Vulvovaginitis

...initis can affect women of all ages and is extremely common. ... Vulvovaginitis is inflammation or infection of the vulva and vagina. ... nonspecific vulvovaginitis can occur in girls with poor genital hygiene and is ... Vulvovaginitis can affect women of all ages and is extremely common...

Transfusion reaction

...uspected during blood administration, the safest ... Overview: Patients with acute blood loss or symptomatic anemia frequently ... These nonspecific symptoms also occur with a hemolytic transfusion reaction . ... Complete form HSC 7173 Report of Possible Transfusion Reaction and send t...

Splinter hemorrhages

... Splinter hemorrhage is a nonspecific finding and can be associated with subacute ... endocarditis, probably 5 in every 6 patients won't have splinter hemorrhages . ... Spl...

RPR

... RPR is a three-letter abbreviation that can refer to: ... RPR test measures nonspecific antibodies that are produced when Treponema ... The Rally for the Republic, was a French right-wing political party. Originating from the Union of...

Prostatitis

...is Definition PROSTATITIS overview based on Edgar Cayce readings , Edgar Cayce Remedies ... PROSTATITIS ... The symptoms of prostatitis are nonspecific and mimic many other ... Prostatitis : Patient Oriented Information, Causes, diagnosis and treatment ... Prostatitis is a very common condi...

Polymyalgia rheumatica

... Giant cell arteritis and polymyalgia rheumatica are closely related disorders ... Patients with polymyalgia rheumatica usually have similar nonspecific systemic ... Up-to-the-minute news coverage of national, regional and international news enhanced with ... Questions To Ask Your Doctor About P...
Nonspecific in Biological News

Engineers create intelligent molecules that seek-and-destroy diseased cells

...the ability to target and localize the therapeutic effect, while minimizing nonspecific side effects," she said. Smolke will present the latest applications of ... function in response to those signals. "In a lot of therapies, you have nonspecific side effects or you're balancing the desired effect of the therapy on disea...

Saliva can help diagnose heart attack, study shows

...The device is the size of a credit card and can produce results in as little as 15 minutes. Many heart attack victims, especially women, experience nonspecific symptoms and secure medical help too late after permanent damage to the cardiac tissue has occurred, says John T. McDevitt, principal investigator and...

Biophysical Society announces winners of 2008 Student Travel Awards

...p 2 is Critical for GABAA Receptor Activation. Paula A. Vivas, University of Illinois at Chicago, New Insights into the Transition Pathway from nonspecific to Specific Complex of DNA with Escherichia coli Integration Host Factor. Irmgard Waldner-Scott, Institute of Biophysics and Nanosystems Resea...

Biocapture surfaces produced for study of brain chemistry

...g of the tethered neurotransmitters. The ideal spacing allows large molecules to recognize the functional groups of the small molecule while avoiding nonspecific binding to the surface itself." Because of their selectivity, these materials are suitable for a variety of investigations in biological systems. ...

New test helps identify hepatitis C patients at high risk of developing cirrhosis

... 10,000 U.S. deaths annually. But in the majority of people chronically infected with hepatitis C, the virus causes either no symptoms or vague, nonspecific ones. In around one-third of people chronically infected with the virus, the disease progression is slow and they may never develop cirrhosis, even...

Pittsburgh researchers discover that certain chemicals in the blood may indicate brain injury

...y syndrome, is often difficult even for experienced and astute physicians because caregivers rarely provide a history of trauma, children present with nonspecific symptoms such as vomiting, and the physical examination can be completely normal," said Dr. Berger, who also is an assistant professor of Pediatrics a...
Nonspecific in Biological Technology

Identification of Nonspecific Products Using Melt-Curve Analysis on the iCycler iQ Detection System, Rev A

Marni Brisson, Larissa Tan, Rob Park, and Keith Hamby, Bio-Rad Laboratories, Inc., 2000 Alfred Nobel Dr., Hercules, CA 94547 USA Introduction Real-time PCR* is a powerful and effective technique for accurate quantitation of DNA. Assays...

Study Finds Noninvasive Blood Test for Liver Fibrosis May Alleviate Need for Liver Biopsies for Some Patients with Chronic Hepatitis C

...es employ an algorithm that incorporates levels of nonspecific biomarkers as well as the patient's age and gender...pecific to liver fibrosis, with assessments of the nonspecific biomarkers bilirubin, gamma-glutamyl transferase (...on, and to compare it with two indices that employ nonspecific biomarkers, aspartate aminotranaminase (AST)-plate...

Tigris Pharmaceuticals Presents Results of Breast Cancer Research at AACR Annual Meeting

...lopment of this difficult to treat disease." About AFP-464 AFP-464, a Lysol prodrug of aminoflavone (AF), undergoes rapid conversion to AF by nonspecific plasma esterases. It has shown a unique pattern of growth inhibitory activity in the NCI's 60 tumor cell line screen, with breast, ovarian, lung and ...

New Independent Research Study Indicates That Cylex's ImmuKnow Test May Identify Kidney Transplant Patients at Risk for Early Acute Rejection

... first 90 days following kidney transplant. The authors of the Transplantation article conclude that pre-transplant assessment of donor-specific and nonspecific immune parameters with ImmuKnow "may identify recipients who can benefit from closer clinical and immunological surveillance to allow for tailored imm...

Glossary for The BioPharm Guide to Fermentation and Cell Culture

... antibody or antigen from a sample (from serum, for example) by adding the corresponding antigen or antibody to that sample. adsorption nonspecific adherence of substances in solution or suspension to cells or other particulate matter. adventitious agents Acquired, sporadic, a...

QIAGEN Fast Cycling PCR Kit

...tes specific primertemplate annealing and simultaneously reduces nonspecific annealing (Figure 3). Amplification of nonspecific products, primer-dimer formation, and background smear are minim...
Nonspecific in Biological Products

Peroxide Block for Image Analysis from ScyTek Laboratories

Description:... This reagent has been developed for use with immunohistochemical (IHC) techniques for the reduction of nonspecific background staining due to endogenous peroxidase. Traditional methods describe blocking peroxidase with hydrogen peroxide. This reagent employs hydr...
Company:ScyTek Laboratories

DeStreak Reagent from GE Healthcare, formerly Amersham Biosciences

Description:... DeStreak Reagent, 1 ml. Improves reproducibility and quality of 2-D gels by preventing streaking.Eliminates extra spots caused by nonspecific oxidation of proteins.Stabilizes proteins throughout entire 2-D runs, ensuring simplified, well-resolved protein patterns.Ideal for both analytical a...
Company:GE Healthcare, formerly Amersham Biosciences

StabilGuard Biomolecule Stabilizer from SurModics, Inc.

Description:...tains the activity of antibodies and other biomolecules that are absorbed or immobilized to solid substrates, by stabilizing biomolecules and blocking nonspecific binding sites. The shelf-life of StabilGuard Biomolecule Stabilizer is 3 years when stored at 4C. Product samples available upon request....
Company:SurModics, Inc.

UltraLink Immobilized NeutrAvidin from Pierce Biotechnology, Inc.

Description:... When nonspecific binding is a problem in your application, Pierce o...de a biotin-binding protein with exceptionally low nonspecific binding properties. NeutrAvidin does not contain c...idin, NeutrAvidin has no carbohydrate, eliminating nonspecific binding problems due to sugars. No interaction ...
Company:Pierce Biotechnology, Inc.

Macro-Prep High Q Support, 500 ml from Bio-Rad

Description:...mer matrix allows high flow rates at moderate pressures, while the macroporous beads enhance access to ionic sites, and the hydrophilic matrix reduces nonspecific binding. Macro-Prep High Q support is a high-capacity strong anion exchanger with very high flow rates and resolution. It has Cl- as the counterion; n...
Company:Bio-Rad

GeneChoice TEMPase II DNA Polymerase from GeneChoice, Inc.

Description:... • Heat activated • Eliminates nonspecific products due to inactivity at room temperature • Excellent specificity allows extension through DNA regions which contain repeats and seconda...
Company:GeneChoice, Inc.
Nonspecific in Biological Definition

Polymerase chain reaction

...ues A more recent method which excludes a temperature cycle, but uses enzymes, is helicase-dependent amplification . A style of PCR that reduces nonspecific primer annealing is Touchdown PCR . Real-Time PCR is a quantative PCR technique. Uses of PCR PCR can be used for a broad variety of exp...
Nonspecific in Biological Dictionary

Trans-splicing

...cing model predicts that the downstream portion of ... There are large numbers of trans - splicing applications, each governed by the ... Such nonspecific trans - splicing can be used to identify alternative splice sites, ... ...

Streptavidin

...n monomer is composed of ... Streptavidin biotin-binding protein immobilized to agarose beads, UltraLink ... Streptavidin generally has less nonspecific binding than avidin (from chicken ... Streptavidin products that produce high quality results. ... to avidin, streptavidin has no carbohydra...

Repressor

...its physical properties. ... Lac Repressor Binding to DNA. for the Atlas of Macromolecules in Protein Explorer ... 1OSL: Lac repressor bound to nonspecific DNA 18-mer. ... The Repressor is an armored personnel carrier, used by the Adeptus Arbites and ... Retrieved from "http://wh40k.lexicanum.com /wi...

Nuclease

...ure of ... Nuclease and protease tests are also performed with the test component at a ... Micrococcal Nuclease (S7 Nuclease ) is a relatively nonspecific ... nuclease -free ... The nuclease as a model for protein folding, Molec. Cell. Biochem., 23, ... Nuclease BAL-31 exonuclease degrades bo...

Lac repressor

...tor, and an operator.... Lac Repressor Binding to DNA. for the Atlas of Macromolecules in Protein Explorer ... 1OSL: Lac repressor bound to nonspecific DNA 18-mer. ... Lac repressor Lac Repressor molecule more details... The lac repressor is a DNA-binding protein which inhibits the ...

Brachial

...inct plexus disorder ... Idiopathic brachial neuritis is a well defined clinical condition that most ... MRI of the left brachial plexus showed nonspecific signal abnormality with T2 ... Brachial plexus injury — Comprehensive overview covers diagnosis, treatment of this potentially ... Newborns can s...
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(Date:7/8/2015)... 2015  Trovagene, Inc. (NASDAQ: TROV ), ... the launch of a study that aims to ... (PCM) technology for predicting response to treatment in ... of the novel immunotherapy agents Yervoy® (ipilumumab), a ... The 50-patient study will be led by researchers ...
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