NimbleGen

Baylor College of Medicine increases fleet of Roche Genome Sequencer FLX Systems to 10 instruments

...an gene parts, or exons, for sequence analysis, reducing the dependence on large-scale polymerase chain reaction. With this combination of 454 and nimblegen methods, we have an unprecedented ability to detect changes across the human genome, said Gibbs. The new Genome Sequencer FLX systems will also be...

NIH Awards Emory $3.6 Million for Schizophrenia Gene Research

... controls (individuals without schizophrenia) for CNV throughout the entire human genome. The new technology uses "DNA chips," manufactured by nimblegen Systems, Inc., that can compare DNA copy number differences in a reference genome to the genomes of the individuals being screened. Scientists can arr...

Effects of Multiple Copies of Genes on Disease Risk

... Washington University School of Medicine in St. Louis and the biotech firm nimblegen Systems Inc. have successfully tested a technique for identifying// newly r...idated many of them using other technologies." Graubert is working with nimblegen to conduct a follow-up analysis of gene copy number variation in the mouse ...

Genetics Of Mental Retardation

...c events. The researchers were able to pinpoint the region of the specific deletion using NimbleGen's high-resolution CGH microarrays. "The ability of nimblegen to rapidly generate custom-designed, high-density oligo arrays targeted to the specific chromosomal regions we were interested in provided us the key ...

NimbleGen in Medical Technology

Microarray Sequence Capture Speeds Large-Scale Resequencing of Targeted Genomic Regions

...esearchers at Baylor College of Medicine and Roche nimblegen Inc., a fully integrated part of Roche Applied Sci...icine, and the Environment (GME) conference, Roche nimblegen and 454 Life Sciences, working with Dr. Richard Gi...form the market for DNA sequence analysis." Roche nimblegen is a leading innovator, manufacturer, and supplier...

NimbleGen in Biological News

Rapid approach to identify influenza A virus mutations and drug resistance developed

...g," said Gerd Maass, Ph.D., CEO of Roche NimbleGen. GIS scientists used nimblegen arrays in a similar way during the SARS outbreak in 2003, to understand the...Gen's custom-developed microarrays: The first arrays developed by Roche nimblegen were designed, manufactured and shipped to Singapore just four days after t...

Microarray sequence capture speeds large-scale resequencing of targeted genomic regions

... Researchers at Baylor College of Medicine and Roche nimblegen Inc., a fully integrated part of Roche Applied Science, today have publishe...r Institutes Genomes, Medicine, and the Environment (GME) conference, Roche nimblegen and 454 Life Sciences, working with Dr. Richard Gibbs, professor and Direct...

Novel experiment documents evolution of genome in near-real time

.... Palsson's team used comparative genome sequencing technology developed by nimblegen Systems Inc., a Madison, WI-based biotech firm, to identify changes that oc...ubunits were determined with comparative genomic sequencing technology from nimblegen Systems, and further analyzed with technology from Sequenom Inc., a San Die...

NIAID researchers show how promising TB drug works

...roarray-based technique, called comparative genome sequencing, developed by nimblegen Systems, Inc. (Madison, WI). This was the first time the technique has been...ify a protein involved in TB drug resistance, notes Dr. Barry. Using the nimblegen technique, which effectively re-sequences the entire genome of the bacteriu...

Whole genome promoter mapping - Human Genome Project v2.0?

... Investigators from the University California, San Diego (UCSD) Branch of the Ludwig Institute for Cancer Research (LICR) and nimblegen Systems have developed an efficient method to identify thousands of regulatory sequences in the human genome, according to a study published today in ...

NimbleGen in Biological Technology

Genomics researcher Hood joins NimbleGen board

Madison, Wis. - Dr. Leroy Hood, a prominent molecular biologist and genomics researcher, has joined the board of directors of NimbleGen Systems , a Madison biotechnology firm. Hood, who is co-founder and president of the Seattle-based Institute for Systems Biology , will serve as chairman of...

Madison biotech NimbleGen files for IPO; one of states' best-funded firms

Madison, Wis. Providing few details, NimbleGen Systems announced on Friday afternoon that it has filed for an initial public offering. The share price and number of shares are yet to be determined. J.P. Morgan Securities is taking a lead role, with Thomas Weisel Partners, Leerink-Swann & Co...

IPO-bound NimbleGen traveling in fast company

Madison, Wis. - It has yet to turn a profit, and it operates in a biotech space where the competition is global in scope, but the decision by Madison research tool manufacturer NimbleGen Systems to file an initial public offering and raise up to $75 million is the latest bit of evidence that th...

California Grants SeqWright License to Operate as a Clinical Laboratory

...rtners on previously developed and validated assays. On a similar note, SeqWright has recently been named as an Authorized Service Provider for nimblegen Capture Arrays. These arrays enable whole-exome and custom-targeted enrichment of genomic DNA. The enriched genomic DNA can then be sequenced on one...

Conference Zeroes in on Homegrown Innovation - 20th Life Science & Venture Conference Full of High-Tech Insights

...rs, a product that fills a hole in the market, and the management team to make it happen. Baird already has invested in two Madison-area companies, nimblegen and TomoTherapy, that it believes fit the bill. We think they both have potentially revolutionary technology with a defensible IP position, said Pa...

Investors Pick Favorites at Life Science Conference

...ies in Wisconsin. NeoClone is probably more of a seed stage company. But nimblegen is probably a mezzanine-level investment. NeoClone produces monoclonal antibody products for the biotechnology and research markets, while nimblegen Systems, Inc. NimbleGen's technology facilitates microarrays of genome sequ...

Wisconsin company with SARS diagnostic role lands $13 million investment

... Madison, Wis. nimblegen , a Madison biotech firm that played a leading role in determining the orig...ontrol an epidemic, a very slow process that can take more than a week. But nimblegen developed a SARS-specific detection chip to help scientists determine where...

Stem-cell patent holders view of the California challenge

...expression of hES cells and of specific cell lineages derived from hES cells using gene chip arrays produced by NimbleGen, one of WARFs start-ups. The nimblegen technology developed at UW allows researchers to easily produce customized arrays for gene expression analysis. Dr. Thomson stated that it is his desi...

Cellular Dynamics hits market with UW research heavyweights

...lth. These novel drug screens promise to speed the development of many new safe and effective drugs." Bob Palay and his brother Tom are founders of nimblegen Systems, which also is a tenant in University Research Park. Other tenants include notable bioscience companies Third Wave Technologies, GenTel, OpGen...

Madison biochip research offers geneticists a big view through a small window

...unctions toward complex systems, complex pathways," said Stan Rose, CEO of nimblegen Systems . Headquartered in Madison, nimblegen links with University of Wisconsin to use and advance research in biochips....

More>>

NimbleGen in Biological Dictionary

Base modification

...tions in human disease ... Modified Nucleotides. CleanAmp™ Products. nimblegen Randomers. Products Index ... Base Modified Ribonucleoside Triphosphates. Catalog ... Modified Nucleotides. CleanAmp™ Products. nimblegen Randomers. Products Index ... Base Modified 2'-Deoxyribonucleoside Trip...