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Nevirapine in Medical News

Prolonged nevirapine in breast-fed babies prevents HIV infection but leads to drug-resistant HIV

Babies born to HIV-positive mothers and given the antiretroviral drug nevirapine through the first six weeks of life to prevent infection via breast-feeding are at high risk for developing drug-resistant HIV if they get infected anyway, a team of researchers report. But the investigators hi...

Once-daily Nevirapine Has More Side-effects Than Twice-daily Dose

Once-daily nevirapine (Viramune) is associated with a higher risk of rash, leading to treatment discontinuation or interruption//, than twice-daily dosing of the drug, according to Canadian research published in the January edition of HIV Medicine. The investigators also found that individuals who ...

HIV Drug a Double-Edged Sword for Infants

... nevirapine protects during breast-feeding, but resistant dise...an. 18 (HealthDay News) -- The antiretroviral drug nevirapine may help prevent babies of HIV-positive mothers fr...available. Given the higher chance of a baby on nevirapine acquiring treatment-resistant HIV, the authors cal...

Researchers estimate lives lost due to delay in antiretroviral drug use for HIV/AIDS in South Africa

...er-to-child transmission prophylaxis program using nevirapine (an anti-AIDS drug) was not implemented, the autho...he paper, the government restricted use of donated nevirapine and blocked funds for more than a year from the Gl...gelheim announced in July 2000 that it would offer nevirapine free of charge for five years for the prevention o...

HIV Drug Might Spur Resistant Strains of Virus

...reast-feeding to prevent mom-to-baby transmission, nevirapine could have downside, study finds TUESDAY, Aug. 5 (HealthDay News) -- The drug nevirapine -- widely used in developing countries to prevent ...nt women in Zimbabwe who received a single dose of nevirapine when they went into labor. The women had received ...

Drug Regimen Prevents AIDS Transmission Via Breast Milk

...rol group, included a single dose of the AIDS drug nevirapine (Viramune) plus one week of treatment with the dru...Retrovir). The other regimens added daily doses of nevirapine or nevirapine as well as zidovudine until the age of 14 weeks. ...

Canadian Company Receives Final Tender Approval From Rwanda For Vital AIDS Drug

...ent simplify the process of getting urgently needed drugs to Africa. Apo Triavir is a combination of 300 mg Zidovudine, 150 mg Lamivudine and 200 mg nevirapine and was evaluated and approved under the provision of the CAMR by Health Canada. TriAvir fully conforms to all Health Canada regulations and requireme...

Drug Helps Prevent Breast-Feeding Moms From Passing on HIV

... 6 weeks of nevirapine greatly reduced infant infections in Africa, India...Feb. 6 (HealthDay News) -- The antiretroviral drug nevirapine greatly reduces the risk that HIV-infected mothers...rding to a study conducted in Africa and India. nevirapine is already in widespread use in developing countri...

Thomson Scientific Introduces a New Quarterly Report Identifying the 'Movers and Shakers' in the U.S. Generics Industry

...aragraph IV challenge on the drug oxaliplatin, Zhejiang Huahai Pharmaceutical Group Co Ltd, a Chinese company that has received tentative approval for nevirapine 200mg tablets under the President's Emergency Plan for Aids Relief (PEPAR) program, and GeneraMedix Pharmaceuticals Inc., an American company based in...

Overlooked Mutation Can Spur HIV Drug Resistance

...r), the first drug ever approved to fight HIV; and nevirapine (Viramune), one of a group of powerful antiretrovi...ll be least prone to resistance. In the case of nevirapine and other widely used RTIs, AIDS experts thought t...ate because it confers some level of resistance to nevirapine and zidovudine, which are drugs belonging to two d...
Nevirapine in Medical Technology

New Results From ARTEN Study of Nevirapine Plus Tenofovir and Emtricitabine (TDF/FTC) Versus Boosted Protease Inhibitor Regimen of Atazanavir/Ritonavir Plus TDF/FTC Revealed

CAPE TOWN, South Africa , July 20 /PRNewswire/ -- New data became available today at the 5(th) International AIDS Society Conference from ARTEN ( A tazanavir/ R itonavir on a background of T enofovir and E mtricitabine [Truvada(R)] versus N evirapine). ARTEN is an open-label, multi-c...

Boehringer Ingelheim Initiates NEwArT Study Comparing Viramune(R) (nevirapine) to a Ritonavir-Boosted Atazanavir-based Regimen in Treatment-Naive HIV Patients

...NEwArT trial may help patients and physicians better understand the role of nevirapine within today's evolving treatment strategies and provide more information o...ctor of the Orlando Immunology Center. The NEwArT (efficacy and safety of nevirapine compared With Atazanavir boosted with Ritonavir and a background of Truvada...
Nevirapine in Biological News

Efavirenz-based initial therapies associated with better outcomes in HIV-infected adults

... and death compared to patients taking nevirapine. nevirapine is the most frequently prescribed drug for patient...ment of International Health. "Patients started on nevirapine had an increased risk of virologic failure and dea...nucleoside reverse transcriptase inhibitor such as nevirapine or efavirenz in resource limited settings. Nearly ...

Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants

...to the start of the study, and all of the infants received a single dose of nevirapine and continuous zidovudine therapy after birth. At either two or five mon...fants' blood, the investigators observed high, inhibitory concentrations of nevirapine that were above those thought necessary to protect against HIV infection. D...
Nevirapine in Biological Technology

Ardea Presents Preclinical Data on Novel Next Generation Non-Nucleoside Reverse Transcriptase Inhibitors Demonstrating Potent Anti-HIV Activity Against Resistant Viruses

... in this series are potent against both wild-type and the most common NNRTI-resistant viruses and are more active than efavirenz (Sustiva(R), BMS) and nevirapine (Viramune(R), Boehringer-Ingelheim) against a broad panel of NNRTI-resistant clinical isolates. "Safer, better tolerated NNRTIs that also work again...

FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy

...in patients on INTELENCE treatment in V106I/M, V108I, Y188L, V189I, G190S/C and R356K. -- Cross-resistance to delavirdine, efavirenz, and/or nevirapine is expected after virologic failure with an INTELENCE-containing regimen. DUET-1 and -2 Tolerability In the DUET-1 and -2 studies, the most co...

A simple and rapid LC-MS/MS method for the simultaneous determination of nine antiretroviral drugs commonly used in Europe (protease Inhibitors and non-nucleoside reverse transcriptase inhibitors)

...ined using the proposed hardware configuration are summarized below. Figure 2 shows the structure of some of the drugs tested in this study. nevirapine is a NNRTI drug while the others belong to the PI group. MRM transitions for each of the measured analytes are listed in Figure 3. ...
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