Prolonged nevirapine in breast-fed babies prevents HIV infection but leads to drug-resistant HIV
Babies born to HIV-positive mothers and given the antiretroviral drug nevirapine
through the first six weeks of life to prevent infection via breast-feeding are at high risk for developing drug-resistant HIV if they get infected anyway, a team of researchers report. But the investigators hi...
Once-daily Nevirapine Has More Side-effects Than Twice-daily Dose
(Viramune) is associated with a higher risk of rash, leading to treatment discontinuation or interruption//, than twice-daily dosing of the drug, according to Canadian research published in the January edition of HIV Medicine. The investigators also found that individuals who ...
HIV Drug a Double-Edged Sword for Infants
protects during breast-feeding, but resistant dise...an. 18 (HealthDay News) -- The antiretroviral drug nevirapine
may help prevent babies of HIV-positive mothers fr...available.
Given the higher chance of a baby on nevirapine
acquiring treatment-resistant HIV, the authors cal...
Researchers estimate lives lost due to delay in antiretroviral drug use for HIV/AIDS in South Africa
...er-to-child transmission prophylaxis program using nevirapine
(an anti-AIDS drug) was not implemented, the autho...he paper, the government restricted use of donated nevirapine
and blocked funds for more than a year from the Gl...gelheim announced in July 2000 that it would offer nevirapine
free of charge for five years for the prevention o...
HIV Drug Might Spur Resistant Strains of Virus
...reast-feeding to prevent mom-to-baby transmission, nevirapine
could have downside, study finds
TUESDAY, Aug. 5 (HealthDay News) -- The drug nevirapine
-- widely used in developing countries to prevent ...nt women in Zimbabwe who received a single dose of nevirapine
when they went into labor. The women had received ...
Drug Regimen Prevents AIDS Transmission Via Breast Milk
...rol group, included a single dose of the AIDS drug nevirapine
(Viramune) plus one week of treatment with the dru...Retrovir). The other regimens added daily doses of nevirapine
as well as zidovudine until the age of 14 weeks.
Canadian Company Receives Final Tender Approval From Rwanda For Vital AIDS Drug
...ent simplify the process of getting
urgently needed drugs to Africa.
Apo Triavir is a combination of 300 mg Zidovudine, 150 mg Lamivudine
and 200 mg nevirapine
and was evaluated and approved under the provision of
the CAMR by Health Canada. TriAvir fully conforms to all Health Canada
regulations and requireme...
Drug Helps Prevent Breast-Feeding Moms From Passing on HIV
... 6 weeks of nevirapine
greatly reduced infant infections in Africa, India...Feb. 6 (HealthDay News) -- The antiretroviral drug nevirapine
greatly reduces the risk that HIV-infected mothers...rding to a study conducted in Africa and India.
is already in widespread use in developing countri...
Thomson Scientific Introduces a New Quarterly Report Identifying the 'Movers and Shakers' in the U.S. Generics Industry
...aragraph IV challenge on the drug oxaliplatin, Zhejiang Huahai
Pharmaceutical Group Co Ltd, a Chinese company that has received tentative
approval for nevirapine
200mg tablets under the President's Emergency Plan
for Aids Relief (PEPAR) program, and GeneraMedix Pharmaceuticals Inc., an
American company based in...
Overlooked Mutation Can Spur HIV Drug Resistance
...r), the first drug ever approved to fight HIV; and nevirapine
(Viramune), one of a group of powerful antiretrovi...ll be least prone to resistance.
In the case of nevirapine
and other widely used RTIs, AIDS experts thought t...ate because it confers some level of resistance to nevirapine
and zidovudine, which are drugs belonging to two d...
Ardea Presents Preclinical Data on Novel Next Generation Non-Nucleoside Reverse Transcriptase Inhibitors Demonstrating Potent Anti-HIV Activity Against Resistant Viruses
... in this series are potent against both wild-type and the
most common NNRTI-resistant viruses and are more active than efavirenz
(Sustiva(R), BMS) and nevirapine
against a broad panel of NNRTI-resistant clinical isolates.
"Safer, better tolerated NNRTIs that also work again...
FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy
...in patients on INTELENCE treatment in V106I/M, V108I, Y188L, V189I, G190S/C and R356K. -- Cross-resistance to delavirdine, efavirenz, and/or nevirapine
is expected after virologic failure with an INTELENCE-containing regimen.
DUET-1 and -2 Tolerability
In the DUET-1 and -2 studies, the most co...
A simple and rapid LC-MS/MS method for the simultaneous determination of nine antiretroviral drugs commonly used in Europe (protease Inhibitors and non-nucleoside reverse transcriptase inhibitors)
...ined using the proposed hardware configuration are summarized below.
Figure 2 shows the structure of some of the drugs tested in this study. nevirapine
is a NNRTI drug while the others belong to the PI group. MRM transitions for each of the measured analytes are listed in Figure 3.