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Neurotransmitters in Medical News

Live recordings of cell communication

...her through vesicles - a nano-sized container loaded with neurotransmitter molecules. A vesicle fuses with the membrane surrounding a neuron, releases neurotransmitters into the surroundings that are detected by the next neuron in line. However, we still lack a more detailed understanding of how the fusion of vesicles...

Avipaxin Is First Entrant in Medical Arsenal for Neuro-Endocrine-Immune Connection(C) Product and Testing Protocols

...ction(C). Elevated pro-inflammatory cytokine levels lead to imbalances in neurotransmitter concentrations and raised hormone (cortisol) levels. neurotransmitters are responsible for people's mood, concentration, sleep, and other mental and emotional functions. Cytokine-induced neurotransmitter imbalances are re...

One step closer to an artificial nerve cell

... of "delivery electrode" that instead releases the neurotransmitters that brain cells use to communicate naturally. The...ea pigs. "The ability to deliver exact doses of neurotransmitters opens completely new possibilities for correcting ...sible to program the unit such that the release of neurotransmitters takes place as often or as seldom as required in o...

Boys May Feel a Genetic Pull Toward Gangs

... from more than 2,500 teens who participated in the National Longitudinal Study of Adolescent Health. The MAOA gene is believed to affect levels of neurotransmitters such as dopamine and serotonin that are related to mood and behavior, according to the study. Previous research found that the "warrior gene" is more ...

Neuromed Announces that Merck & Co., Inc. Terminates Research Collaboration and License Agreement for Compounds Targeting N-Type Calcium Channels

...ry of calcium into the neuron. When a pain signal is transmitted, the channel opens and the calcium concentration increases, triggering the release of neurotransmitters from synaptic vesicles, thereby sending the pain signal to the brain where it is perceived as pain. About Neuromed Neuromed is a privately h...

Brain Imaging Study Confirms Cognizin(R) Citicoline Boosts Mental Function; to be Presented at International Society of Sports Nutrition Annual Conference

... cell membranes and helping subjects maintain normal cognitive function as they age. It achieves these results by increasing the production of several neurotransmitters in the central nervous system, including acetylcholine, norepinephrine and dopamine. In the study, 16 subjects were randomly chosen to receive 50...

'Singing brains' offers epilepsy and schizophrenia clues

...is work with our medical colleagues. In particular, we hope that the study of gamma oscillation frequency will provide a new window into the action of neurotransmitters such as GABA and how their function is compromised in diseases such as epilepsy and schizophrenia." "We also believe that our findings could have i...

New System for Managing Sleep Disorders Aims to Improve Sleep Through Brain Chemistry

...tests for potential imbalances in the hormones and neurotransmitters that regulate sleep. This protocol enhances a clin...hanced non-invasive lab test that measures the key neurotransmitters and hormones in sleep biochemistry. The concentra... the profile. Other sleep-influencing hormones and neurotransmitters measured include cortisol, y-amino butyric acid (G...

Mind and Body Reunite as Premier Indianapolis Psychiatry Practice Adds Integrative Medicine

...on the interplay of hormones, nutrition and lifestyle on the balance of the neurotransmitters and the immune system. She is the recipient of Fort Wayne Newspaper's 2008 ...fect of nutrition and hormones on the brain chemistry. The body cannot make neurotransmitters without the appropriate building blocks." Dr. LaSalle's practice inclu...

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Commercial Availability of Savella(TM)

...es. Savella is a dual-reuptake inhibitor that, in-vitro, preferentially blocks the reuptake of norepinephrine with higher potency than serotonin, two neurotransmitters thought to a play a central role in the symptoms of fibromyalgia. Savella will be marketed by Forest and its licensor, Cypress Bioscience. Pierre Fabr...
Neurotransmitters in Medical Technology

Addrenex Pharmaceuticals Expands Product Pipeline by Licensing New Drug to Treat Narcolepsy

...overactive or improperly regulated adrenergic system, a group of hormones and brain chemical messengers known as neurotransmitters. These hormones and neurotransmitters regulate diverse physiologic functions such as stress, pain, sleep and blood pressure. Addrenex's lead products are Clonicel(R) for the treatmen...

Mission Pharmacal Launches CitraNatal(R) Assure Prescription Prenatal Vitamin

... some women reduce severe nausea or vomiting during pregnancy(6). It also helps the body maintain blood glucose levels, metabolize proteins, formulate neurotransmitters for normal nerve cell communication and makes hemoglobin to carry oxygen to tissues(7). Pregnant women may experience improved comfort with C...

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Positive Results of Phase III Study of Milnacipran for the Management of Fibromyalgia

...ipran Milnacipran is a dual-reuptake inhibitor that preferentially blocks the reuptake of norepinephrine with higher potency than serotonin, two neurotransmitters thought to play a central role in the symptoms of fibromyalgia. Milnacipran is being developed for fibromyalgia in the United States jointly by Fores...

CeNeRx BioPharma Initiates Phase II Clinical Trial of Its Novel Antidepressant Agent Tyrima(TM)

...Similar to the mechanism of conventional monoamine oxidase A inhibitors (MAOI), the triple-action mechanism of Tyrima elevates the levels of three key neurotransmitters (serotonin, norepinephrine and dopamine) that positively affect mood and anxiety, compared to the one or two neurotransmitters addressed by most curre...

CeNeRx BioPharma Finalizes Plans to Initiate Phase II Trials for Its Novel Antidepressant Agent Tyrima(TM) Using Innovative Brain Imaging Study

...icacy as we move Tyrima into Phase II trials." Like conventional MAOI agents, the triple-action mechanism of Tyrima elevates the levels of three key neurotransmitters (serotonin, norepinephrine and dopamine) that positively affect mood and anxiety. In contrast, most current antidepressant drugs affect only a single ...

GlaxoSmithKline Announces New Drug Application and Phase III Results for Rezonic(TM)/Zunrisa(TM) (Casopitant)

...tional product and has not yet received approval from any regulatory agency. About NK-1 Receptor Antagonists and CINV Two key pathways and two key neurotransmitters are associated with CINV. The central pathway is activated by substance P and mediated by neurokinin (NK-1) receptors that are highly concentrated in ...

CeNeRx BioPharma Announces Successful Completion of Phase l Clinical Program for Novel Antidepressant Agent Tyrima(TM)

...ase ll program in the second quarter of 2008." Like conventional MAOI agents, the triple-action mechanism of Tyrima elevates the levels of three key neurotransmitters (serotonin, norepinephrine and dopamine) that positively affect mood and anxiety. In contrast, most of the current leading antidepressant drugs affect...

Milnacipran Demonstrated Significant Improvement in Pain and the Core Symptoms of Fibromyalgia Syndrome, Data Show

...n Milnacipran is a unique dual-reuptake inhibitor, which preferentially blocks the reuptake of norepinephrine with higher potency than serotonin, two neurotransmitters known to play an essential role in regulating pain and mood. It has been approved for the treatment of depression in over 32 countries, with real-worl...

New Study: Pine Bark Extract Boosts Nitric Oxide (NO) Production

... activity and build when subjected to regular elevated labor. "This study suggests that when taking Pycnogenol(R), more NO is provided in response to neurotransmitters allowing for better expansion of arteries to carry more blood. This process serves to meet the enhanced oxygen demand of the performing muscle and avo...

DOV 21,947 Demonstrates Significant Body Weight and BMI Reductions in Drug- Compliant Subjects in Phase Ib Clinical Study

...le at the end of 2008. About DOV 21,947 Clinical research indicates that co-administrating drugs that, in combination, inhibit reuptake of the three neurotransmitters most closely linked to depression - serotonin, norepinephrine and dopamine - can produce greater overall efficacy than currently marketed antidepressa...
Neurotransmitters in Medical Dictionary

Vesicles

...bstances within a cell. Vesicles form naturally because of the... In a neuron synaptic vesicles or neurotransmitter vesicles store various neurotransmitters that are released at the synapse. The release is regulated by a voltage-dependent calcium channel. Vesicles are essential for... vesicle n. ...

Phenylalanine

... phenylalanine , with reviews on the health benefits, biological functions, dietary sources, daily dosage, and side ... A brief description of how neurotransmitters actually work in the brain. ... Anhedonia Enantiomer Essential Amino Acids Neurotransmitter Opioids Phenylalanine ... Phenylalanine forms part...

Catecholamines

...e, breathing ... catecholamines Catecholamines comprise important neurotransmitters and hormones , of which the main ones are dopamine , noradrenaline cat...f amines derived from catechol that have important physiological effects as neurotransmitters and hormones and Describes how catecholamine testing is used, when c...
Neurotransmitters in Biological News

Study shows enzyme builds neurotransmitters via newly discovered pathway

The study, which was directed by Scripps Research Professor Benjamin Cravatt, Ph.D., is being published in the September 8 issue of The Journal of Biological Chemistry. The new study describes a pathway-different than the one previously suggested-for the biosynthesis of neurotransmitter lipids, N...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

...king, learning, memory or emotion is mediated by a large number of chemical neurotransmitters and neuromodulators. Disturbances in neurotransmitter function are seen as ...insons disease (Pachter et al., 2006). In studying how the brain cells, neurotransmitters and neuropeptides interact and communicate with the rest of the body, resea...

UBC researchers develop new method to study gambling addictions

..." the study finds that gambling decisions can be impaired or improved with drugs that affect brain dopamine and serotonin levels suggesting that these neurotransmitters may moderate gambling behaviour. "For most individuals, gambling is enjoyable and harmless, but for others, it is as destructive as being addicted ...

Drug prevents seizure progression in model of epilepsy

...sing compound for treatment in epilepsy patients. While most anticonvulsants currently used to treat epilepsy work to directly inhibit the activity of neurotransmitters that causes seizures, few compounds interact with specific ion channels, especially potassium channels. The researchers believe that targeting the...

Translating the conversation between the brain and blood vessels

...said. New work underway Dr. Schreihofer's laboratory has identified neurotransmitters that are at work in the brain stem that regulate sympathetic nervous activity. neurotransmitters relay signals from one nerve cell to another, allowing nerve cells to 'talk...

Tiny but toxic: MBL researchers discover a mechanism of neurodegeneration in Alzheimer's disease

...he "fast axonal transport" system inside the neuron, Brady found. This transport system has motor proteins that move various kinds of cargo (including neurotransmitters and the associated protein machinery for their release) from place to place in the neuron on microtubule tracks. Brady's findings are complemented...

'Neurological work-arounds' offer hope to people with monoamine-related disorders

...y also be able to compensate for problems with key neurotransmitters such as serotonin and dopamine. This finding may o...heir brain cells to be unable to release monoamine neurotransmitters such as serotonin and dopamine. Fruit flies were u...nvenient for genetic experiments and have a set of neurotransmitters that is nearly identical to that of humans. And as...

Protein that regulates hormones critical to women's health found in pituitary

...rogue protein" that plays a role in the release of neurotransmitters and hormones in the brain. The scientists foun... membranes of small sacs, or vesicles, filled with neurotransmitters and hormones within nerve terminals. When an elect...iggers the spilling out of the vesicle's contents neurotransmitters and hormones so they can act on other cells. ...

Pitt research identifies new target in brain for treating schizophrenia

...e activity in the orbitofrontal cortexa brain region responsible for cognitive activity such as decision makingcould be triggered by the two different neurotransmitters linked to schizophrenia: dopamine and glutamate. Brain activity was then normalized both by established antipsychotic medications that regulate only d...

Brain-nourishing molecule may predict schizophrenia relapse

...BDNF levels on a more even keel. About a dozen older schizophrenia medications and a handful of new ones adjust the activity level of a variety of neurotransmitters in the brain, Dr. Pillai says. Animal studies have shown the drugs have a differing impact on BDNF as well. Most initially improve the level then, wit...
Neurotransmitters in Biological Technology

Addrenex Pharmaceuticals Licenses New Compound to Sciele Pharma for the Treatment of Hypertension and Other Potential Indications

...arget specific subtypes of the alpha-2 receptor. Alpha-2 receptors are present throughout the brain and body. They bind with adrenergic hormones and neurotransmitters such as adrenalin and noradrenalin to control a wide range of physiological functions. Malfunctions in the alpha-2 receptor pathway have been implicat...

Knee brace generates electricity from walking

... access to electricity. And the scientists say similar mechanisms could be built into prosthetic knees other implantable devices such as pacemakers or neurotransmitters that today require a battery, and periodic surgery to replace that battery. "A future energy harvester might be implanted along with such a device ...

Forest and Cypress Announce Submission of New Drug Application for Milnacipran for the Treatment of Fibromyalgia Syndrome

... Milnacipran is a unique dual-reuptake inhibitor, which preferentially blocks the reuptake of norepinephrine with higher potency than serotonin, two neurotransmitters known to play an essential role in regulating pain and mood. It has been approved for a non-pain condition in over 50 countries, with real-world comme...

Development of an NK2 neuropeptide receptor binding assay using LEADseeker Multimodality Imaging System

...idely distributed throughout the central and peripheral nervous system where they act via G protein-coupled receptors (NK1, NK2, and NK3 receptors) as neurotransmitters and neuromodulators. They are also considered key mediators in the communication between neurons (particularly sensory neurons) and effector cells (e....
Neurotransmitters in Biological Definition

Amino acid

...of the plant hormone ethylene . In addition to amino acids for protein synthesis, there are other biologically important amino acids, such as the neurotransmitters glycine , GABA and glutamate , as well as carnitine (used in lipid transport within a cell ), ornithine , citrulline , homocysteine , hyd...

Biological psychology

... may be looked at as a hybrid of neuroscience and psychology . Practitioners of biological psychology may use their knowledge of the brain , from neurotransmitters to the cerebral cortex to treat their patients. Others may use this knowledge to search for biological causes for common mental illnesses, such as ...

Brain

...s in the brain and throughout the body by sending various chemicals called neurotransmitters across gaps known as synapses . Small invertebrates such as insects may...h the new techniques of electrodes and the electroencephalogram (EEG). neurotransmitters were discovered and investigated by a number of scientists, including Otto...

Enzyme

...ses : all those enzymes that can eliminate a group from a molecule to form a double bond and vice versa. Monoamine oxidase (MAO): oxidize certain neurotransmitters and biologically active amines NADH dehydrogenase : the first complex in the electron transfer chain , transferring electrons from NADH to c...

Neuron

...ctrical excitation along the axon. Arrival of an action potential at the tip of an axon triggers the release of neurotransmitter at a synaptic gap . neurotransmitters can either stimulate or suppress (inhibit) the electrical excitability of a target cell. An action potential will only be triggered in the target cell...

Neuroscience

...ary to, or may replace, the top-down approach of psychology . The concern of neuroscience includes such diverse topics as the operation of neurotransmitters at the synapse ; the biological mechanisms that underlie learning (both declarative learning and motor learning ); how genes contribute...

Neurotransmitter

... neurotransmitters are chemicals that are used to relay, amplify an...s showTocToggle("show","hide") 1 Types of neurotransmitters 2 Mechanism of action 3 Post-synaptic effect 4 Specific actions 5 Common neurotransmitters 6 See also 7 External links T...

Signal transduction

...rane . Several "signaling molecules", such as the neurotransmitters that allow nerve cells to communicate across s...t only cells in the vicinity of the emitting cell. neurotransmitters represent an example. Autocrine signals affe...blood vessels . Regulation of exocytosis of neurotransmitters . Cellular immune response . Resea...

Selective serotonin reuptake inhibitor

...ls. The neuron that sends the information releases neurotransmitters (with serotonin among them) into that gap. The neurotransmitters are then recognized by receptors on the surface ...tion, in turn, relays the signal. About 10% of the neurotransmitters are lost in this process, the other 90% are releas...

Synapse

...this interface, the membranes of the two cells flank each other across a slender gap, the narrowness of which enables signalling molecules known as neurotransmitters to pass rapidly from one cell to the other by diffusion . This gap is sometimes called the synaptic cleft. Such synapses are asymmetric both in st...
Neurotransmitters in Biological Dictionary

Second messenger

...of second messenger signaling for use in models of ... The second messenger information algorithms are part of a larger model which ... How neurotransmitters Activate Second Messenger Systems. Stephen M. Stahl, M.D., Ph.D. ... intracellular second messenger that carries the information from the ... ...

Neurotransmitter

...r n. A chemical substance, such as acetylcholine or dopamine, that transmits nerve impulses across a ... The neurotransmitter chemical then ... neurotransmitters After Galvani had shown, in 1742, that electrical stimulation of the nerve to the muscle of a frog's leg caused the muscle to Neurotransmitte...
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