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Neurotransmitter in Medical News

Webinar on June 25 to Focus on Opportunity for Treating Chronic Pain, Migraine and Muscle Spasticity Through Inhibition of Neurotransmitter Glutamate

TorreyPines Therapeutics' CEO Neil Kurtz, M.D., to Moderate Discussion Following Presentations by Tony Yaksh, Ph.D.; Jerome Goldstein, M.D.; and Alan J. Tuchman, M.D. LA JOLLA, Calif., June 20 /PRNewswire/ -- A Webinar hosted by TorreyPines Therapeutics, Inc. (Nasdaq:...

Estrogen also a potential neurotransmitter

According to a Johns Hopkins University behavioral neuroscientist evidence is mounting that estrogen, should also be thought of as a neurotransmitter when acting in the brain. // The study was funded by the National institute of mental health. In the same direction is an article by Gregory Ball,...

Live recordings of cell communication

...eases and mental disorders like e.g. depression. Nerve signals travel from one neuron to another through vesicles - a nano-sized container loaded with neurotransmitter molecules. A vesicle fuses with the membrane surrounding a neuron, releases neurotransmitters into the surroundings that are detected by the next neur...

Addrenex Pharmaceuticals Announces Licensing Agreement With Dream Pharma

...ulation. Addrenex Pharmaceuticals is based in Durham, N.C., on the edge of Research Triangle Park. The company's mission is to explore the impact that neurotransmitter regulation has on a variety of diseases and disorders. Addrenex identified adrenergic regulation as its initial research focus. Adrenergic dysregulati...

Avipaxin Is First Entrant in Medical Arsenal for Neuro-Endocrine-Immune Connection(C) Product and Testing Protocols

...use. These studies also revealed a decrease in the neurotransmitter norepinephrine and an increase in the neurotransmitter serotonin. Historically, neurotransmitters,...inflammatory cytokine levels lead to imbalances in neurotransmitter concentrations and raised hormone (cortisol) level...

Dementia induced and blocked in Parkinson's fly model

..., according to Galvin. Shaw's lab has linked sleep loss to changes in the dopaminergic system of the brain, the part of the brain that produces the neurotransmitter dopamine and is at the center of the damage caused by Parkinson's. "In healthy flies, sleep deprivation decreases dopamine receptor production and ...
Neurotransmitter in Medical Technology

TorreyPines Therapeutics to Host Webinar at 11 a.m. EDT Today on the Opportunity for Treating Chronic Pain, Migraine and Muscle Spasticity Through Inhibition of Neurotransmitter Glutamate

TorreyPines Therapeutics' CEO Neil Kurtz, M.D., to Moderate Discussion Following Presentations by Tony Yaksh, Ph.D.; Jerome Goldstein, M.D.; and Alan J. Tuchman, M.D. LA JOLLA, Calif., June 25 /PRNewswire/ -- A Webinar hosted by TorreyPines Therapeutics, Inc. (Nasdaq:...

Jazz Pharmaceuticals and UCB Announce Second Phase III Study of Sodium Oxybate in Patients With Fibromyalgia Meets Primary Endpoints

...b.com Notes to the editor About Sodium Oxybate Sodium oxybate is the sodium salt form of gamma-hydroxybutyrate, an endogenous neurotransmitter and metabolite of GABA. While the precise mechanism of action is unknown, the effects may be mediated in part through interaction with GABA(B) and GHB...

Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia

...nd will manage registrations accordingly. About Sodium Oxybate Sodium oxybate is the sodium salt form of gamma-hydroxybutyrate, an endogenous neurotransmitter and metabolite of GABA. While the precise mechanism of action is unknown, the effects may be mediated in part through interaction with GABA(B) and GHB...

Autism Studies Presented at Mid-Atlantic Research Consortium Meeting

...nedy Krieger Institute, presented the results of animal studies that shed light on how autism operates in humans. By altering the flow of serotonin, a neurotransmitter in the brain, Blue showed that mice behaved less socially, had impairments in fine motor functions and increased repetitive behaviors. The changed ani...

Key Protein May Lead to Faster Acting Anti-Depression Drugs

... was awarded the 2000 Nobel Prize in Medicine or Physiology, helped establish p11 as an important protein that regulates signaling in the brain by the neurotransmitter serotonin, which has long been linked to mood. Michael Stern Parkinson's Research Center scientists begun studying p11 because the serotonin system w...

Kyowa Hakko Kirin Announces Development Policy for Anti-Parkinson's Disease Drug KW-6002 (Istradefylline)

...s of this disease result from the progressive degeneration of certain nerve cells located in a specific area in the brain leading to a shortage of the neurotransmitter dopamine. This results in decreased activation of dopamine receptors in the brain which is thought to cause the motor symptoms. The symptoms of Parkin...
Neurotransmitter in Medical Definition

Depolarization-induced suppression of inhibition

...B1 receptors, which act presynaptically to reduce neurotransmitter release. Contents 1 History ...projection neurons to GABA , the main inhibitory neurotransmitter in the central nervous system. GABA is typicall...s thought to be due to a reduction in pre-synaptic neurotransmitter release for 2 reasons. 1) The magnitudes of sponta...
Neurotransmitter in Medical Dictionary

Vesicles

...nclosed sac that stores or transports substances within a cell. Vesicles form naturally because of the... In a neuron synaptic vesicles or neurotransmitter vesicles store various neurotransmitters that are released at the synapse. The release is regulated by a voltage-dependent calcium channel. Vesic...

Tryptophan

... reviews on the health benefits, biological functions, dietary sources, daily dosage, and side ... L Tryptophan is the precursor to Serotonin, a neurotransmitter in the brain, ... Tryptophan naturally converts to this neurotransmitter. ... Tryptophan is an essential amino acid that must be obtained th...

Serotonin

...l motility and is ... Discovered 32 years ago, serotonin has been found to be the most diverse ... Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter in the brain that ... The functions of serotonin are numerous and appear to involve control of ... Serotonin has been noted to produce an inhi...

Phenylalanine

...daily dosage, and side ... A brief description of how neurotransmitters actually work in the brain. ... Anhedonia Enantiomer Essential Amino Acids neurotransmitter Opioids Phenylalanine ... Phenylalanine forms part of your daily diet, and plays a certain role in maintaining your health, vitality and wellb...

Alcoholism

...lcoholism sound serious, that's because it is. ... The only indication of early alcoholism may be the unpleasant physical responses ... another neurotransmitter associated with alcoholism and other addictions. ... Alcoholism is drinking alcoholic beverages at a level that ... known common cause of alc...
Neurotransmitter in Biological News

Treating chronic pain, migraine & muscle spasticity through inhibition of neurotransmitter glutamate

LA JOLLA, CA, June 20, 2008 A Webinar hosted by TorreyPines Therapeutics, Inc. (NASDAQ: TPTX) at 11 a.m. EDT on June 25 will bring together industry experts to discuss the opportunity of treating chronic pain, migraine and muscle spasticity through the inhibition of the neurotransmitter glutamat...

Low levels of neurotransmitter serotonin may perpetuate child abuse across generations

Infant abuse may be perpetuated between generations by changes in the brain induced by early experience, research shows at the University of Chicago shows. A research team found that when baby rhesus monkeys endured high rates of maternal rejection and mild abuse in their first month of life, t...

Short stressful events may improve working memory

...prefrontal cortex, a key region that controls learning and emotion. Specifically, they demonstrated that acute stress increases transmission of the neurotransmitter glutamate and improves working memory. "Stress hormones have both protective and damaging effects on the body," said Zhen Yan, professor of physio...

Genetic marker linked to problem behaviors in adults with developmental disabilities

...odes monoamine oxidize A or MAOA. MAOA is involved in the regulation of the neurotransmitter serotonin, which is linked to appetite and mood, and the neurotransmitter and hormone norepinephrine, which is linked to the fight-or-flight response...

Promising new treatment for Alzheimer's suggested based on Hebrew University research

... be more protected from the devastating effects of the disease, since the mutated protein (the enzyme that is the product of the gene) breaks down the neurotransmitter acetylcholine at a slower rate than in those who have the normal gene. The result is that the carriers maintain higher levels of this neurotransmitter...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

...otransmitters and neuromodulators. Disturbances in neurotransmitter function are seen as the main cause of mental and ... specially tailored therapies to influence various neurotransmitter systems. The discovery of specific receptors in th...op drugs, which act on specific receptors within a neurotransmitter system. The pharmacological progress achieved in r...
Neurotransmitter in Biological Technology

Ceregene Receives Additional Grant From Michael J. Fox Foundation to Expand Long-Term Testing of CERE-120 Patients

...nts and gait, are caused by a loss of dopamine-containing nerve cells in the substantia nigra, which project their axons to the putamen. Dopamine is a neurotransmitter involved in controlling movement and coordination, so Parkinson's patients exhibit a progressive inability to initiate and control physical movements....

Inaugural Kavli Prize ceremony and symposia: Sept. 8-11 (Oslo, Norway)

...and function of neurogenesis in the adult mammalian brain" Eric Gouaux (Oregon Health & Science University, USA). Topic: "Structure and mechanism of neurotransmitter receptors and transporters" Sten Grillner (Karolinska Institute, Sweden). Topic: "Kavli Laureate Lecture" Thomas Jessell (Columbia University, USA...

FDA Approves PRISTIQ(TM) for the Treatment of Adult Patients with Major Depressive Disorder

... potentially life-threatening serotonin syndrome may occur when EFFEXOR XR is coadministered with other drugs that may affect the serotonergic neurotransmitter systems. Concomitant use of EFFEXOR XR with MAOIs is contraindicated. If concomitant use of EFFEXOR XR with an SSRI, SNRI, or a triptan is cli...

Addrenex Pharmaceuticals Reaches Milestone with Filing of NDA for First Product, CloniBID, to Treat Hypertension

...arch Triangle Park. The company was formed in 2006 by a practicing physician and a drug development expert with the mission to explore the impact that neurotransmitter regulation has on a variety of diseases and disorders. Addrenex identified adrenergic regulation as its initial research focus. Adrenergic dysregulati...

Amarin Signs Agreement to Acquire Ester Neurosciences

... field of acetylcholinesterase ("AChE"), developed by Professor Hermona Soreq of the Hebrew University of Jerusalem. AChE is a degrading enzyme of the neurotransmitter acetylcholine, the imbalance of which plays a central role in a range of currently incurable and highly debilitating neurodegenerative conditions. The...

Anavex advances drug candidate for treatment of Alzheimer's disease

...loned and shown to be distinct from any known receptor class. In the CNS, they are involved in the modulation of neurotransmitter receptor function, neurotransmitter release and response, as well as memory and learning processes, demonstrating potential neuroprotective and anti-amnesic properties. The modulatory ac...
Neurotransmitter in Biological Products

Rabbit Anti-Glutamate receptor 1, phospho (Ser845) Polyclonal Antibody, Unconjugated from GeneTex

Description:... Polyclonal Phosphorylated Anti-GluR1 Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainate receptors that are...
Company:GeneTex

Rabbit Anti-GluR4 Antibody, Unconjugated from Lab Vision

Description:... Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oli...
Company:Lab Vision

Superfusion System, Raiteri's Method from myNeuroLab.com

Description:...es. Synaptosomes are concentrated in the synaptic bouton. Synaptosomes may be centrifuged and isolated from other cellular debris. Abnormalites in neurotransmitter release have been proposed in many pathological condtions. Conditions of release may be studied in isolated synaptosome preparations.The Superfusion ...
Company:myNeuroLab.com
Neurotransmitter in Biological Definition

Neurotransmitter

Neurotransmitters are chemicals that are used to relay, amplify and modulate electrical signals between a presynaptic and a postsynaptic neuron . A chemical is classified as a neurotransmitter if it respects the following conditions: It is synthesized endogenously It is available ...

Diffusion

... topics List of physics topics Mass transfer Materials science Mechanical ventilation NaKATPase Nervous system neurotransmitter Nitric oxide Nobel Prize in Physiology or Medicine Osmosis Osmotic Quorum sensing Respiration Reverse osmosis ...

Enzyme

...ic acid to tetrahydrofolic acid DNA gyrase : catalyzes the negative supercoiling of prokaryotic DNA Glutamate decarboxylase : synthesizes the neurotransmitter GABA in the brain Glutathione peroxidase : protects cells by converting hydrogen peroxide to water Isomerase : all those enzymes which conve...

Ion channel

...s of nerve and muscle, and the voltage-gated calcium channels that control neurotransmitter release in pre-synaptic endings . Ligand-gated channels open in re...nclude the "nicotinic" Acetylcholine receptor , AMPA receptor and other neurotransmitter -gated channels. Cyclic nucleotide-gated channels , Calcium-activate...

Muscle

...ed by the nerves , the motor nerves and motoneurons in particular. All skeletal muscle and many smooth muscle contractions are facilitated by the neurotransmitter acetylcholine . Muscles and muscular activity account for most of the body's energy consumption. Muscles store energy for their own use in the f...

Nervous system

...hin the nervous system occurs by two primary mechanisms: Within neuronal nerve fibers by way of action potentials Between neurons by way of neurotransmitter diffusion across synapses . Vertebrate nervous systems The nervous systems of vertebrate animals are often divided into a central nervo...
Neurotransmitter in Biological Dictionary

Neurotransmitter

Chemical structure of D-aspartic acid, a common amino acid neurotransmitter . ... Drugs targeting the neurotransmitter of such systems affects the whole system; ... neurotransmitter n. A chemical substance, such as acetylcholine or dopamine, that transmits nerve impulses across a ... ...

Membrane transporter

...e . Transport proteins are integral membrane proteins; that is... The dopamine transporter is a membrane -spanning protein that binds the neurotransmitter dopamine; DAT provides the primary mechanism through which dopamine is cleared from synapses, transporting dopamine from the synapse into... Dis...

Epinephrine

... Epinephrine is a hormone and neurotransmitter that participates in the "fight or flight" response of the sympathetic nervous system. It is a catecholamine, a sympathomimetic monoamine p...
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