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Neuronal in Medical News

St. Jude Scientists Discover a New Mechanism Controlling Neuronal Migration

Understanding how neurons migrate to their proper place during brain development will offer insights into how malfunctions in the machinery cause epilepsy and mental retardation MEMPHIS, Tenn., July 15 /PRNewswire-USNewswire/ -- The molecular machinery that helps brain cells migra...

Novel Photoconductive Cellular Depolarization Technology Reveals Insight Into Neuronal Growth, Guidance, and Regeneration

BOSTON, Jan. 30 /PRNewswire/ -- Neurosilicon's novel Photoconductive Stimulation Device (PSD) was highlighted in the recent scientific publication by Hung and Colicos titled, Astrocytic Ca2+ Waves Guide CNS Growth Cones to Remote Regions of Neuronal Activity. The article appearing in the November ...

Abbott Researchers Target Neuronal Nicotinic Receptors for Treatment of Pain and Cognition

Scientists to Present Data and Discuss Emerging Advances in Basic Research and Clinical Science at Neuroscience 2007 Satellite Symposium ABBOTT PARK, Ill., Nov. 1 /PRNewswire-FirstCall/ -- The human brain relies on chemicals called "neurotransmitters" that nerve cells use to communicate to ...

Low level of neuronal receptor linked to mild cognitive impairment and Alzheimer's disease

Results of a new study indicate a strong link between the loss of the neuronal receptor LR11and onset of mild cognitive impairment (MCI), often a harbinger of Alzheimer's disease. LR11, like all receptors, selectively receives and binds specific substances. Researchers found reduced levels of ...

Alternative Splicing in Neuronal Development

In the July 1st issue of G&D, Dr. Douglas Black (UCLA) and colleagues detail how alternative splicing is reprogrammed during neuronal development. Alternative splicing refers to the processing of an RNA transcript into different mRNA molecules by including some exons and excluding others. Spe...

Cocaine Exposure can Alter Neuronal Development in Zebrafish

Researchers from Boston University School of Medicine (BUSM) have shown that prenatal cocaine exposure in zebrafish (which share the majority of the same genes with humans) can alter neuronal development and acutely dysregulate the expression of circadian genes and those affecting melatonin signal...
Neuronal in Medical Technology

FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended Release for the Treatment of ADHD in Children and Adolescents

...atment of ADHD is not fully understood, preclinical research suggests this selective alpha-2A agonist strengthens working memory and prefrontal cortex neuronal firing.(6) This research supports the use of guanfacine for the treatment of ADHD.(6) Safety was also evaluated during these pivotal trials and...

Neuroscience Researcher Has Positive Message for International Alzheimer's Awareness Week, July 6 - 12: 'Even Though World Economy is Declining, Alzheimer's Research is Advancing'

...cium-overloaded neurons and thereby restore normal neuronal function." Underwood says Quincy's own stud...t cognitive function could be improved by lowering neuronal calcium concentrations. "We asked 83 healthy...memory, focus, and concentration by lowering their neuronal calcium," says Underwood. "We are very optimistic...

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

...y is a chronic neurological disease characterised by abnormal discharges of neuronal activity causing seizures. Clinically, these manifest as convulsions or jer..., preventing its return to the active state, and thereby reduces repetitive neuronal firing. The efficacy of ESL has been demonstrated in three randomised, plac...

More Gene Mutations Linked to Autism Risk

...rsity of Pennsylvania School of Medicine. "We identified additional autism susceptibility genes, many of which, as we previously found, belong to the neuronal cell adhesion molecule family involved in the development of brain circuitry in early childhood." He added that the team discovered many "private" gen...

CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders

...function and survival of several types of neurons. Both Alzheimer's disease and Huntington's disease involve the degeneration of certain neurons, and neuronal damage is also implicated in the peripheral neuropathies associated with diabetes, kidney disease, cancer chemotherapy and other conditions. In precl...

Shire Announces Study Results of the Effects of INTUNIV(TM) (Guanfacine) Extended Release on Secondary Measures in Children with ADHD and Oppositional Symptoms

...atment of ADHD is not fully understood, preclinical research suggests this selective alpha-2A agonist strengthens working memory and prefrontal cortex neuronal firing. This research supports the use of guanfacine for the treatment of ADHD. In pivotal clinical trials, safety data showed that adverse ev...
Neuronal in Medical Products

Free Activin AB ELISA Test

Description:...teins have been shown to affect the growth and differentiation of a number of cell types, including cultured rat anterior pituitary cells, gonadal and neuronal cell lines, and hematopoietic progenitor and erythroleukemia cells (2). Two binding proteins have been described for the Activins and Inhibins: Foll...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin A ELISA Test

Description:...teins have been shown to affect the growth and differentiation of a number of cell types, including cultured rat anterior pituitary cells, gonadal and neuronal cell lines, and hematopoietic progenitor and erythroleukemia cells (2). Two binding proteins have been described for the Activins and Inhibins: Foll...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin B ELISA Test

Description:...teins have been shown to affect the growth and differentiation of a number of cell types, including cultured rat anterior pituitary cells, gonadal and neuronal cell lines, and hematopoietic progenitor and erythroleukemia cells (2). Two binding proteins have been described for the Activins and Inhibins: Foll...
Company:Diagnostic Systems Laboratories, Inc.

VisPath Analyzer (VPA)

Description:... important part of most general physical exams. Thats because eye movements and pupil responses are controlled by an extremely sensitive set of visual neuronal centers and pathways that are affected by many medical conditions. The VisPath Analyzer (VPA) provides pre-programmed visual stimuli and automates the...
Company:Visual Pathways, Inc.

Magnes 3600 WH

Description:...els and its full cortical coverage, provides the highest detector density available, along with high sampling rates, allowing study of a wide range of neuronal activity. The Magnes 3600 WH also allows a choice of detector configurations and can be equipped with radial magnetometers, axial gradiometers or a co...
Company:4-D Neuroimaging

ACE - REA Hypertension / Cardiac Evaluation, Cardiovascular 001-RK-ACD Angiotensin Converting Enzyme

Description:...e of this glycoprotein shows a single polypeptide chain, a polysaccharide residue and a zinc atom. ACE is present in many different cell types such as neuronal cells and renal proximal tubular cells, but is mostly found in endothelial cells. It is attached to the endothelial surface membrane by an anchor pept...
Company:ALPCO Diagnostics

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Neuronal in Medical Definition

Depolarization-induced suppression of inhibition

...ment (i.e. a 300-400 µm slice of brain, with intact axons and synapses) where a single neuron is "depolarized" (the normal −70 mV potential across the neuronal membrane is reduced, usually to −30 to 0 mV) for a period of 1 to 10 seconds. After the depolarization, inhibitory GABA mediated neurotransmission i...

Pathology

...s type IV - Gaucher's disease - Niemann-Pick disease - Farber disease - Fabry's disease - Metachromatic leukodystrophy - Krabbe disease neuronal ceroid lipofuscinosis ( Batten disease ) - Cerebrotendineous xanthomatosis - Cholesteryl ester storage disease ( Wolman disease ) Other li...
Neuronal in Medical Dictionary

Vesicles

... for... vesicle n. A small bladderlike cell or cavity. Anatomy. ... neuronal vesicles which occur in neuronal terminals in which acetylcholine is the transmitter. ... Vesicles - O...

Seizure

... An epileptic seizure is a transient symptom of excessive or synchronous neuronal activity in the brain. It can manifest as an alteration in mental state, tonic or clonic movements, convulsions, and various other psychic symptoms . ...

Seizures

... An epileptic seizure is a transient symptom of excessive or synchronous neuronal activity in the brain. It can manifest as an alteration in mental state, tonic or clonic movements, convulsions, and various other psychic symptoms . ...

Norepinephrine

...ds of sympathetic nerve fibres, where they serve as chemical mediators for conveying the nerve... ... (10(-6) M), consistent with stimulation of neuronal norepinephrine release. ... Norepinephrine . 8-Hydroxy-2-(di-n-propylamino )tetralin ... Learn about taking duloxetine (Cymbalta) to treat fibr...

Neuropathy

...y causes. ... kinds of peripheral neuropathy with many different ... Diabetic neuropathy . Diabetic retinopathy. Diabetes and pregnancy ... neuronal ischemia is a well-established characteristic of diabetic neuropathy . ... Neuropathy is a condition that causes tingling or numbness in cert...

Medial

...ings in Life. Neurons in the medial superior olive (MSO) are thought to encode interaural time ... Medial Superior Olive of the Big Brown Bat: neuronal Responses to Pure Tones, ... Whereas initial learning activated medial temporal structures, subsequent runs provoked circumscribed posterior ...
Neuronal in Biological News

Caltech scientists reveal how neuronal activity is timed in brain's memory-making circuits

PASADENA, Calif.Theta oscillations are a type of prominent brain rhythm that orchestrates neuronal activity in the hippocampus, a brain area critical for the formation of new memories. For several decades these oscillations were believed to be "in sync" across the hippocampus, timing the firing of...

Iron is involved in prion disease-associated neuronal demise

Imbalance of iron homeostasis is a common feature of prion disease-affected human, mouse, and hamster brains, according to a new study by Dr. Neena Singh and colleagues at Case Western Reserve University School of Medicine, alongside collaborators from Creighton University. These findings, publish...

Chemist receives NIH funding to unravel tricks of neuronal wiring

Joshua Maurer, Ph.D., assistant professor of chemistry in Arts & Sciences, has received a four-year, $1,216,000 grant from the National Institute of Mental Health for research titled "Unraveling Development: New Materials for Understanding Neuronal Wiring." Maurer's long term objective is to d...

Claudin 11 stops the leaks in neuronal myelin sheaths

Devaux and Gow demonstrate how a tight junction protein called claudin 11 makes the neuronal myelin sheath a snug fit. The study will be published in the December 1, 2008 issue of the Journal of Cell Biology ( www.jcb.org ). Like the rubber coating on a copper wire, the myelin sheatha membran...

How neuronal activity leads to Alzheimer's protein cleavage

Amyloid precursor protein (APP), whose cleavage product, amyloid-b (Ab), builds up into fibrous plaques in the brains of Alzheimer's disease patients, jumps from one specialized membrane microdomain to another to be cleaved, report Sakurai et al. Although there is no definitive evidence that Ab ...

Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain

Research Highlights: Mechanism of action of compound found to induce neurotransmitter activity in brain cells The findings may lead researchers to develop potential novel therapies to treat Alzheimer's disease, amyotrophic lateral sclerosis, Huntingtons disease, epilepsy, stroke/ischemia, d...

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Neuronal in Biological Technology

Efficient RNAi-mediated gene silencing in neuronal cells using QIAGEN siRNA and TransMessenger Transfection Reagent*

Anna M. Krichevsky and Kenneth S. Kosik Center for Neurologic Diseases, Brigham and Womens Hospital, Harvard Medical School, Boston, MA, USA Genetic manipulations using neuronal cells are notoriousl...

Effectene Transfection Reagent provides efficient gene delivery to primary neuronal cell cultures

Jochen Meier, Ivonne Strmel, Radu Iosub, Sonja Schmidt, and Rosemarie Grantyn Developmental Physiology, Johannes Mller Institute, Humboldt University Medical School (Charit), Berlin, Germany Efficient deliv...

Oprah, Luke Skywalker and Maradona -- new study investigates how our brains respond to them

...in the areas they recorded from. Moreover, Professor Quian Quiroga found neurons responding to his own pictures and name, thus suggesting that such neuronal representations can be generated relatively fast, because he was unknown to the patient a day or two before the recording took place. Said Professo...

Biovista Inc. Announces Positive Efficacy Results in a Pre-Clinical Trial of its BVA-601 Repositioned Drug for Epilepsy

...sorder characterized by recurrent unprovoked seizures. These seizures may be transient signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain. Epilepsy is one of the world's oldest recognized conditions, affecting around 50 million people worldwide. Fear, discrimination...

Ten Top Latin American Scientists Named 2009 Pew Fellows in the Biomedical Sciences

...mon A. Jorquera, Ph.D. Laboratory of J. Troy Littleton, M.D., Ph.D. Massachusetts Institute of Technology neuronal communication Andres Klein, Ph.D. Laboratory of Matthew P. Scott, Ph.D. Stanford University ...

Novel Once Daily Anti-Epileptic Zebinix(R) Approved in the European Union

...th the resting state which means it is less likely to interfere with normal neuronal function (12). "A significant number of patients with partial-onset ...y is a chronic neurological disease characterised by abnormal discharges of neuronal activity causing seizures. Clinically, these manifest as convulsions or jer...
Neuronal in Biological Products

Anti-Glycine Transporter 2, Neuronal (GLYT2) Polyclonal Antibody, Unconjugated from CHEMICON

Description: Glycine Transporter 2, Neuronal (GLYT2). The antiserum has been tested on tissue sections from the central nervous system. The staining pattern obtained with AB1773 corresponds to the pattern described using in situ hybridization with probes to GLYT2 mRNA and to what has been described for glyciner...
Company:CHEMICON

Rat Frozen Neuronal Tissue Microarray from Zyagen Laboratories

Description: Zyagen tissue microarrays are derived from frozen embedded tissue blocks, which are subjected to rigorous quality control procedures to ensure the highest quality. Tissues of each array are manually assembled in one block, sectioned at a thickness of 7 microns and mounted on coated slides. Sections...
Company:Zyagen Laboratories

Rat Paraffin Neuronal Tissue Microarray from Zyagen Laboratories

Description: Zyagen tissue microarrays are derived from Paraffin embedded tissue blocks, which are subjected to rigorous quality control procedures to ensure the highest quality. Tissues of each array are manually assembled in one block, sectioned at a thickness of 5 microns and mounted on coated slides. Sectio...
Company:Zyagen Laboratories

Mouse Frozen Neuronal Tissue Microarray from Zyagen Laboratories

Description: Zyagen tissue microarrays are derived from frozen embedded tissue blocks, which are subjected to rigorous quality control procedures to ensure the highest quality. Tissues of each array are manually assembled in one block, sectioned at a thickness of 7microns and mounted on coated slides. Sections ...
Company:Zyagen Laboratories

Human BMP-5 ELISA development Kit, DuoSet Economy Pack from R&D Systems

Description:...te the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. Similar to other TGF-beta family proteins, BMPs are highly conserved across animal species. This DuoSet ELISA Development kit contains the bas...
Company:R&D Systems

rNeural Stem Cell (rNSC)Kit from AlphaGenix, Inc.

Description:... Rat neural stem cell kits are intended for the in vitro growth and commitment to neuronal and glial lineage differentiation, of cultured fetal rat neural stem and progenitor cells expanded using FGF-2....
Company:AlphaGenix, Inc.
Neuronal in Biological Definition

Down syndrome

... from a peroxide damage. Some scientists believe that the treatment of Down syndrome neurons with free radical scavengers can substantially prevent neuronal degeneration . Oxidative damage to neurons results in rapid brain aging similar to that of Alzheimer's disease . Another chromosome 21 gene that...

Long-term potentiation

...ted protein kinase cascade in hippocampal long term potentiation". J Biol Chem 272 (31), 19103-6. PMID 9235897 ^ Sweatt JD (2001) "The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory". J Neurochem 76 (1), 1-10. PMID 11145972 ...

Memory

...y . It may be that short-term memory is supported by transient changes in neuronal communication, whereas long-term memories are maintained by more stable and... specific brain regions. Learning and memory are attributed to changes in neuronal synapses . Related topics Amnesia Long-term potentiat...

Mitochondrion

...form of ATP , mitochondria play an important role in many important metabolic tasks, such as: Apoptosis Glutamate -mediated excitotoxic neuronal injury Cellular proliferation Regulation of the cellular redox state Heme synthesis Steroid synthesis Heat production (enabling ...

Mitochondrion

...form of ATP , mitochondria play an important role in many important metabolic tasks, such as: Apoptosis Glutamate -mediated excitotoxic neuronal injury Cellular proliferation Regulation of the cellular redox state Heme synthesis Steroid synthesis Heat production (enabling ...

Nervous system

...dary cells involved in nourishment and structural support. Rapid signalling within the nervous system occurs by two primary mechanisms: Within neuronal nerve fibers by way of action potentials Between neurons by way of neurotransmitter diffusion across synapses . Vertebrate nervous sy...
Neuronal in Biological Dictionary

Transgenic

...... CWRU Transgenic Mice and Knockout Mice: Transgenic Core Facility ... The Roth lab developed transgenic mice in which activity of specific neuronal ... [ANDi, the first transgenic Rhesus monkey, carries the gene for a green ... cumbersome technique is not likely to lead to transgenic huma...

Neuroscience

...f the Society of Neuroscience . Nature Neuroscience offers a unique mix of opinion and reviews alongside top ... Selective targeting of specific neuronal populations is crucial to neuroscience . ... Monthly review journal from Nature Publishing Group that publishes peer-reviewed articles providing a...

Motor neuron

...mer's a-z list > motor neuron disease definition ... MOTOR NEURON DISEASES ... Degenerating motor neurons contain ubiquitin-positive neuronal and glial ... This causes motor neuron loss by an unkown mechanism. ... Spasticity is found with upper motor neuron injuries and manifests ...

Hyperpolarization

...olarization are discussed in the following places at Britannica. Assorted References function in nervous systems ( in nervous system (anatomy): The neuronal membrane ) ...of the plasma membrane has a negative charge compared to the outside, the neuron is said to be polarized. Any change in membrane pot...

Glial cells

... inflammation, glial cells "get excited and work against the ... The phenotypic distinction of radial glial cells from the more specialized neuronal ... glial cells with the classical Golgi method alone was ... A hallmark of glial cells is their pronounced ability to migrate. ... Glial ...

Dendrite

...t this article or section be merged with Dendrite (metal) ... What is a dendrite ? The Isothermal Dendritic Growth ... ... how the properties of neuronal dendrites and neural circuits contribute to ... recordings from axons and dendrites , and recording from multiple ... Definition of dendrite ...
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