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Neurogenic in Medical News

A New Approach In Treatment Neurogenic Detrusor Overactivity In Children

Many reports have dealt with the outcome of botulinum-a toxin (BTX-A) detrusor injections in patients with neurogenic or nonneurogenic detrusor overactivity. BTX-A detrusor injections have been described in adult// patients with neurogenic detrusor overactivity due to spinal cord injury. Rese...

UQ research finds speech disorders can be assessed from a distance

...idly and reliably assessed over the internet using a telerehabilitation application. "Having worked clinically with people living with an acquired neurogenic communication disorder, I saw how frustrating it was for both the person with the communication disorder and the clinician if access to these services...

Tengion to Present at 27th Annual JP Morgan Healthcare Conference

...discuss Tengion's completion of its Phase 2 clinical trial in patients with neurogenic bladder due to spina bifida and the company's plans for a Phase 3 trial of its Tengion Neo-Bladder Augment(R) in patients with neurogenic bladder, planned for initiation in the first half of 2009. Dr. Nichtberger...

Japanese encephalitis virus causes 'double trouble' to brain

...n," said Basu. He also went on to state, "The neurological and cognitive deficits in the JE survivors could be related to the drop in NPC cells in the neurogenic region of the brain called the subventricular zone". Neural stem/progenitor cells are the saviours of the brain following any insult or infection a...

JCI table of contents: June 20, 2008

...at activated TRPA1, suggesting that they might contribute to the airway damage that occurs in smoke-related diseases. TITLE: Cigarette smokeinduced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents AUTHOR CONTACT: Pierangelo Geppetti University of ...

Erectile Dysfunction a Strong Harbinger of Heart Trouble

...Dr. E. Scott Monrad, a professor of clinical medicine at Albert Einstein College of Medicine in New York City. "Neuropathy would interfere with the neurogenic responses feeding into proper erection," Monrad said. "And obstruction of blood flow into the arteries reduces the pressure needed to achieve erection...

Scientists obtain anticancer medicines from the elecampe, a wild plant growing in the Mediterranean

...gy Institute of the University of Granada have found out that the plant Dittirichia viscose, known as elecampe, can be used to obtain inhibitors of neurogenic vasodilatation, a significant progress in migraine and cancer treatments. The study, supervised by professors Mara del Mar Herrador and Alejandr...

Stem Cell Activity Deciphered in the Aging Brain

...and memory function in the elderly. One approach being explored is to treat older rats with drugs designed to mimic the action of compounds called neurogenic factors, which encourage stem cells in the brain to divide, Shetty said. The researchers also are grafting neural stem cells grown in culture dishes i...

Indore Surgeon Offers New Hope for Erectile Dysfunction

...t only cure penile problems, but "also lead to an answer for all incurable diseases in the future". "Impotency may be the result of psychogenic, neurogenic or hormonal factors. Vascular disease is one of the leading causes - 90 percent - of erectile dysfunction," Agarwal told IANS on telephone. "Sur...

Brain Swelling Key to Reducing Stroke Fatalities

...hanism in the brain is unclear. But in the skin, a similar process known as neurogenic inflammation is triggered by nerve cells. This results in increased leakine...ys. Blocking substance P reduces skin tissue oedema. “Until recently, neurogenic inflammation was not known to occur in the brain following injury. Our labo...
Neurogenic in Medical Technology

Unlikely Treatment Identified by BrainCells Neurogenesis Platform Improved Clinical Outcomes in Patients Suffering From Depression

... "BCI-952 was selected by our proprietary platform for the compound's neurogenic properties," said Jim Schoeneck, chief executive officer of BrainCells Inc....dictive screening platform, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successful clinical trials in a v...

Preclinical Data Demonstrate Ability to Regenerate an Entire Bladder With Tengion Neo-Bladder Replacement(TM)

...ducting three Phase 2 clinical trials of its Neo-Bladder Augment at 12 leading academic medical centers across the United States: one in children with neurogenic bladder due to spina bifida, one in adults with neurogenic bladder due to spinal cord injury and one in adult patients with overactive bladder (OAB) a...

BrainCells Inc. Initiates Phase 2 Clinical Trial with BCI-540 for Depression with Anxiety

...our understanding of the power of neurogenesis coupled with our proprietary neurogenic platform technology to identify a strong portfolio of clinical candidates, ...dictive screening platform, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successful clinical trials in a v...

Tengion Launches Third Phase 2 Clinical Trial of Regenerated Human Bladder

...on of enrollment of a Phase 2 clinical trial of the Neo-Bladder Augment for neurogenic bladder due to spina bifida and the initiation of a Phase 2 clinical trial of the Neo-Bladder Augment for neurogenic bladder due to spinal cord injury. According to The World Journal of Urol...

Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ

...ter clinical trial of its neo-bladder construct, derived from a patient's own cells. The U.S.-based study is being conducted in 10 adult patients with neurogenic bladder due to spinal cord injuries. Neurogenic bladder is a condition that can occur due to spinal cord injury and may lead to kidney failure and inc...
Neurogenic in Medical Products

Cook® Continence Cuff

Description:... Used for temporary control of male urinary incontinence due to surgery or neurogenic disorder. Supplied non-sterile. Reusable. Intended for single patient use only....
Company:Cook Urological
Neurogenic in Medical Dictionary

Vasodilation

... peristalsis and sphincter of Oddi ... This vasodilation was persistent in the presence of both prazosin ... Nitrosyl factors mediate active neurogenic hindquarter vasodilation in the conscious rat. ... Learn about the prescription medication Tiazac (Diltiazem Hcl), drug uses, dosage, side...

Sphincter

...xplains overactive bladder, detrusor- sphincter dyssynergia, and urine retention, and discusses the symptoms, causes, diagnosis, and treatment of neurogenic bladder. PARIS, FRANCE (UroToday.com) - Dr. Koelbl began the last presentation of the ... Ultrasonographic sphincter volume correlated with the ...

Pulmonary edema

... of Pulmonary Edema including risks, what to expect and when to call the doctor ... Pulmonary Edema . WHAT YOU SHOULD KNOW ... INTRODUCTION neurogenic pulmonary edema (NPE) is an increase in pulmonary interstitial and alveolar fluid due to, and usually developing rapidly after, acute central ...

Neurogenic bladder

... neurogenic bladder refers to dysfunction of the urinary b...atient information resource. ... Risk factors for neurogenic bladder include various birth ... Up-to-t...ernational news enhanced with audio and video ... neurogenic bladder can occur at any age, but ... ...

Nephrogenic Diabetes Insipidus

...Nephrogenic Diabetes Insipidus . ... related disorder called central or neurogenic diabetes insipidus . ... The Diabetes Insipidus Foundation, Inc. ......enic diabetes insipidus is much more common than ... Nephrogenic and neurogenic Diabetes Insipidus (AVPR2) Mental ... Nephrogenic diabetes ins...

Muscle biopsy

...are awake and the area being ... Open biopsy involves a small incision through the skin and into the muscle , so ... Muscle biopsy : ... neurogenic changes in muscle biopsy ... Muscle biopsy shows the presence of scattered necrotic fibers, myophagocytosis, ... An open biopsy involves...

Edema

...cause edema of the legs. ... Edema can occur nearly anywhere in the body. ... Clinical manifestations and diagnosis of edema in adults ... neurogenic pulmonary edema . Overview of heavy ... Article: Sporadic in utero generalized edema caused by mutations in the... Edema . Return to top. Or...

Bladder

...xplains overactive bladder , detrusor-sphincter dyssynergia, and urine retention, and discusses the symptoms, causes, diagnosis, and treatment of neurogenic bladder . Our physician's scope of practice incorporates all areas of urology. ... Cancer of the bladder is the fourth most common cancer amo...
Neurogenic in Biological News

Drug-proof zebrafish reveal secrets of addiction

...fically known for their involvement in brain development. Even more interestingly, as the authors demonstrate, several of these genes are expressed in neurogenic domains of the adult fish brain these are domains where neurons are generated from neural stem cells during adulthood. According to the researchers, ...

Ex vivo neural stem cell expansion

...(Memorial Sloan-Kettering Cancer Center) and colleagues lend new mechanistic insight into the effective generation of neural stem cells outside of the neurogenic niche. Their upcoming paper demonstrates that the polycomb group protein, Bmi-1, maintains forebrain neural stem cell self-renewal. Overexpression ...

Stress may make you itch

...sts that stress may activate immune cells in your skin, resulting in inflammatory skin disease. The related report by Joachim et al., "Stress-induced neurogenic Inflammation in Murine Skin Skews Dendritic Cells towards Maturation and Migration: Key role of ICAM-1/LFA-1 interactions," appears in the November is...

UT Southwestern researchers create molecule that nudges nerve stem cells to mature

...as completely serendipitous that we uncovered this neurogenic [nerve-creating] small molecule," Dr. Hsieh said. "I think it's one of the most powerful neurogenic small molecules on the planet. In theory, this mol...nto non-nerve cells and was more potent than other neurogenic substances in stimulating nerve-cell development. ...

Trainor Lab characterizes gene essential for prenatal development of nervous system

...ion in the spinal cord by coupling progression through the cycle of cell division with differentiation of neural cells by direct activation of two key neurogenic determinants, Neurod and p27Kipl. We were excited to uncover, for the first time, multiple functional roles for a Cux-like homeodomain transcript...

Jefferson urologists studying regenerated neo-bladder to help spinal cord injury patients

...ells. To participate in the study, a patient must be 18 to 65 years of age, have had a spinal cord injury for more than a year and diagnosed with a neurogenic bladder that is not adequately responding to medical therapy. The urologist first performs a biopsy on the patient to retrieve the cells. The cells...

Stem cell activity deciphered in the aging brain

...and memory function in the elderly. One approach being explored is to treat older rats with drugs designed to mimic the action of compounds called neurogenic factors, which encourage stem cells in the brain to divide, Shetty said. The researchers also are grafting neural stem cells grown in culture dishes i...
Neurogenic in Biological Technology

BrainCells Inc. Appoints Philip Jochelson, M.D. Chief Medical Officer and Jason Levin Chief Business Officer

... drug candidates based on what we know about their neurogenic properties from our platform that enables us to co...ze complex pharmacology, and image and measure the neurogenic process. Philip and Jason are top caliber people t...m, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successf...

BrainCells Inc. Appoints David E. Thompson to Its Board of Directors

...ing and operations will be a great asset to us as we continue to expand our neurogenic platform technology and to explore potential strategic collaborations." ... effects. BCI-540 was in-licensed from Mitsubishi Pharma (MPC) based on its neurogenic properties and in previous studies was shown to be well tolerated in more t...

Neuralstem Fills Key Product Development Position

...urrently targeting diseases and injuries of the spinal cord for its first human trials, including ALS and Paraplegia. The company has also developed neurogenic and neuroprotective small molecule compounds targeted at treating depression. For further information, please visit http://www.neuralstem.com . Cau...

REVISED: BrainCells Inc. Expands Series B Financing to $50 Million

...ary platform technology to identify the compound's neurogenic profile, which is comparable to antidepressants on...unmet needs, we find BCI's ability to leverage its neurogenic screening technology to identify and develop new t...m, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successf...

BrainCells Inc. Expands Series B Financing to $50 Million

...ary platform technology to identify the compound's neurogenic profile, which is comparable to antidepressants on...unmet needs, we find BCI's ability to leverage its neurogenic screening technology to identify and develop new t...m, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successf...

Tengion Announces European Orphan Drug Designation for Neo-Bladder Augment

...ficant clinical benefit to those patients with spina bifida who suffer from neurogenic bladder and warrant surgical intervention for their condition. "We are ex...e Neo-Bladder Augment's potential to significantly improve the treatment of neurogenic bladder in spina bifida patients -- a critically underserved patient popula...

BrainCells Inc. Completes $30 Million Initial Closing of Series B Financing

...adult human brain produce new brain tissue, including neurons. With its predictive screening platform, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successful clinical trials in a variety of CNS indications. For more information, visit http://www.braincel...

Preclinical Efficacy Data Demonstrate Ability of Tengion's Neo-Bladder Augment to Restore Bladder Function

...eo-Bladder Augment: one in pediatric patients with neurogenic bladder due to spina bifida, and the other in adult patients with neurogenic bladder due to spinal cord injuries." The purpose...eo-Bladder Augment: one in pediatric patients with neurogenic bladder due to spina bifida, and the other in adul...
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