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Neuroendocrine in Medical News

Frost & Sullivan Recognizes Neotropix's Approach to the Treatment of Small Cell Lung Cancer and Neuroendocrine Cancers

Innovative Therapy Ensures Greater Patient Compliance, Improves Quality of Life MOUNTAIN VIEW, Calif., Jan. 13 /PRNewswire/ -- Based on its recent analysis of the biopharmaceuticals market, Frost & Sullivan recognizes Neotropix, Inc. with the 2009 U.S. Frost & Sullivan Award for ...

The small cell neuroendocrine carcinoma of the ampulla of vater

Ampullary small cell neuroendocrine carcinoma is extremely rare and has only been documented in few case reports and retrospective study. The patients with ampullary small cell neuroendocrine carcinoma usually presented after the age of 60 years, and a male predilection was observed. Only two case...

Avipaxin Is First Entrant in Medical Arsenal for Neuro-Endocrine-Immune Connection(C) Product and Testing Protocols

...tablished in 1999, is devoted to medical solutions that improve health by providing novel laboratory assessments and products in the emerging field of neuroendocrine Immunology (NEI). The company is research and education-focused and has a database that includes results from over 300,000 patients. ...

Delcath Systems Provides Update on Progress

...se Maximum Number of Centers Enrolling Patients to 28 Received Orphan Drug Designation for the Drug Melphalan for the Treatment of Patients with neuroendocrine Tumors. Accomplished Medical Device Executive Eamonn Hobbs Appointed President & CEO Cash as of June 30, 2009 at $8.9 Million Co...

The AGA Foundation awards grant to Dr. Michael Choi to further his research on carcinoid tumors

...t recipient of the Mary Terese Hartzheim Award for neuroendocrine Tumor Research. This new research award was create...vestigators interested in researching carcinoid or neuroendocrine tumors. Dr. Choi is an investigator at Massachuset...elopment, diagnosis and treatment of carcinoid and neuroendocrine tumors," said Sidney Cohen, MD, AGAF, chairman of ...

Patients with lower urinary tract symptoms more likely to suffer from metabolic syndrome

...ight and the prevalence in children has considerably increased. The possibility of pharmaceutically targeting the adipokine system, thus influencing a neuroendocrine pathway that might impact LUTS, is intriguing." ...

Depression May Lead to More Preemies Among Blacks

...said. "What some people experience by being black takes a toll on the physiological system, and over time, wear and tear that occurs across neural, neuroendocrine and immune systems as a result of chronic exposure to stressors lead to health disparities for blacks," Gavin said. "Some of this may manifest itself ...

Genomas Presents Drug-Specific Genetic Determinants of Statin Safety and Efficacy at the XV International Symposium on Atherosclerosis

..., CT) and the University of California, San Francisco . Researchers genotyped 384 SNPs (single nucleotide polymorphisms) from 222 cardiometabolic and neuroendocrine genes with a potential role in determining the safety and efficacy of statins. The study was funded in part by a grant from the National Institute of ...

KLRI Releases 3rd Annual Report On Year's Top Longevity Research Findings

...which increases oxidative stress, and a psychological test, which increases neuroendocrine stress, releasing inflammatory chemicals. Researchers will also look for any link between oxidative stress and neuroendocrine responses. Calorie restriction. Numerous studies have found that re...

Drug therapy reduces neuroblastoma tumor growth in pre-clinical investigation

...h." Vandetanib blocks a family of endothelial growth factors and receptors that promote tumor growth as well as the RET oncogene, which can signal neuroendocrine cells to develop into neuroblastoma cells. Although commonly used in treatment for neuroblastoma, CRA by itself does not have a significant impact aga...
Neuroendocrine in Medical Technology

Lexicon Presents Clinical Data on LX1032 for Carcinoid Syndrome at European Neuroendocrine Tumor Society Meeting

THE WOODLANDS, Texas, March 5 /PRNewswire-FirstCall/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX ), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, announced today that Dr. Philip Brown , senior vice president of clinical develop...

RAD001 Combined with Sandostatin LAR(R) Depot and as Monotherapy Controls Growth of Rare Pancreatic Neuroendocrine Tumors

- 82% of patients with pancreatic neuroendocrine tumors (NET) experienced clinical benefit when treated with daily RAD001 and monthly Sandostatin LAR Depot - 77% of patients with pancreatic NET experienced clinical benefit when treated with ...

Callisto Pharmaceuticals Completes Enrollment of Phase II Trial of Atiprimod in Neuroendocrine Cancer

NEW YORK, Sept. 20 /PRNewswire-FirstCall/ -- Callisto Pharmaceuticals, Inc. (Amex: KAL; FWB: CA4), a developer of new drug treatments in the fight against cancer and gastrointestinal disorders and diseases, announced today that complete enrollment of its Phase II clinical trial of Atiprimod to...

Lilly and New York City Mayor Michael R. Bloomberg Announce Lilly Agrees to be First Tenant of East River Science Park; Issue Urgent Call for Healthcare Reform that Protects Innovation and Jobs

...IMC-11F8 is expected to move into Phase III development by the end of 2009; Phase II testing of IMC-A12 has been expanded to include colorectal, neuroendocrine and lung cancers. Phase III studies of IMC-A12 are expected to begin in either late 2009 or early 2010; IMC-3G3 has recently moved into Phase I...

Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Receives Orphan Drug Designation From EMEA

...designation from the European Medicines Agency. About Carcinoid Syndrome Carcinoid syndrome is a chronic condition caused by metastatic neuroendocrine tumors that usually originate from the gastrointestinal tract. These tumors secrete large amounts of serotonin, which can cause a variety of symptoms...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

...ficant antitumor benefit in patients with advanced neuroendocrine tumors of the midgut - Early data show that...w treatments." Sandostatin LAR in metastatic neuroendocrine midgut tumors Data from the PROMID study (abstr...icant antitumor effect in patients with metastatic neuroendocrine tumors (NET) of the midgut(1). Sandostatin LA...

Dr. James F. Pingpank to Present at Leading Regional Therapies Conference

...phalan (MEL) Administered via Hepatic Arterial Infusion for Patients with Unresectable Hepatic Metastases from neuroendocrine Tumors (MNET) and Multi-institutional Clinical Trials in Regional Therapy for ...

RAD001 Phase II Trial Results Positive in Patients with Advanced Gastric Cancer After Failure of One or More Prior Treatments

...r cell division, cell metabolism and blood vessel growth. RAD001 is being studied in multiple cancer types including advanced kidney, breast and neuroendocrine tumors and lymphoma. Currently, RAD001 is under regulatory review in the US and Europe for the treatment of advanced renal cell carcinoma. The...

New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors

...r surgery in certain patients with newly diagnosed neuroendocrine tumors (NETs) EAST HANOVER, N.J., Jan. 13 /PR...ated antitumor benefit in patients with metastatic neuroendocrine tumors (NETs) of the midgut, according to interim ...cy of O ctreotide LAR in patients with metastatic neuroendocrine MID gut tumors). "Sandostatin LAR has a prov...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

...t approved in the EU in 2003. RAD001 is being evaluated as a single agent or in combination with existing therapies for renal cell carcinoma, neuroendocrine tumors, lymphoma, breast, gastric, lung and other cancers, as well as tuberous sclerosis. About LBH589 (panobinostat) Panobinostat (LBH...
Neuroendocrine in Medical Dictionary

VIPoma

...rows from certain cells ... VIPoma causes cells in the pancreas to produce high levels of a hormone called ... INTRODUCTION VIPomas are rare neuroendocrine tumors that secrete vasoactive ... Radiofrequency Ablation Has a Valuable Therapeutic Role in Metastatic VIPoma . ... VIPoma ... VIPoma is a ...

Prolactinoma

...uitary adenomas over-produce prolactin. What the treatments are and side effects. ... in most cases a prolactinoma can be treated with a ... The neuroendocrine Clinical Center offers detailed outpatient evaluation of all disorders affecting the endocrine function of the hypothalamus and pituitary gland, ....

Lung tumor

...urative." Robert ... PATHOLOGY OF TUMORS OF THE LUNG . Margaret M Grimes, MD. Surgical ... represents the most malignant end of the spectrum of neuroendocrine tumors of the lung ... ...

Larynx

...This is between the pharynx and the trachea. ... The larynx is the phonating mechanism that is specifically designed for voice production. ... neuroendocrine Tumors of the Larynx : Grand Rounds presentation from the Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medic...

Insulinoma

...pancreas that produces too much insulin. ... much insulin production is about as common as insulinoma . ... Insulinoma . An insulinoma is a neuroendocrine tumor deriving mainly from pancreatic islet ... In patients with insulinoma , the ratio rises during fasting. ... Insulinoma Information from...

Immune response

...ruses in order to better understand how it ... Sleep deprivation alters neuroendocrine and immune responses . > Immune system activation and neuroendocrine responses alter sleep. ... Todar's Online Textbook of Bacteriology co...

Hypothalamus

...rols endocrine glands). The pituitary gland lies just below the hypothalamus . ... The hypothalamus and pituitary together are known as the neuroendocrine system of the body. ... brain cells in the hypothalamus produce hormones (such as ... All the colored parts below are the separate segments of t...

Glucagonoma

...er health-related topics at LIVESTRONG.COM, the definitive daily health, fitness, and lifestyle destination... Overview: A glucagonoma is a rare neuroendocrine tumor with nearly exclusive ... In 75-80% of cases, the glucagonoma starts in malignant form, and in 50% of ... Country-specific prevalence ...

Carcinoid tumor

... Carcinoid is a slow-growing type of neuroendocrine tumour, originating in the cells of the neuroendocrine system. Carcinoid tumors produce the va... related neuro-endocrine neoplasms. ... Prognosis. neuroendocrine Tumors . Specific Tumor Locations ... xxxxx...

Carcinoid syndrome

...likely to have a separate cancer ... The Caring for Carcinoid Foundation (CFCF) provides a wealth of ... Carcinoid Syndrome - Mayo Clinic. neuroendocrine Tumors - Dana-Farber Cancer Institute ... Important It is possible that the main title of the report Carcinoid Syndrome is not the name you ex...
Neuroendocrine in Biological News

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

SALT LAKE CITY University of Utah researchers and their colleagues have identified the gene that is mutated in a hereditary form of a rare neuroendocrine tumor called paraganglioma (PGL). The gene, called hSDH5, is required for activation of an enzyme complex that plays a critical role in the che...

Pre-pregnancy depressed mood may heighten risk for premature birth

...actors. "What some people experience by being black takes a toll on the physiological system, and over time wear and tear that occurs across neural, neuroendocrine and immune systems as a result of chronic exposure to stressors lead to health disparities for blacks. Some of this may manifest itself in premature ...

NIH funds research center for women's reproductive health at Einstein

...ynecology and women's health, and of medicine; and Alex Polotsky, M.D., assistant professor of obstetrics & gynecology and women's health. "IGF-I and neuroendocrine Regulation of Female Reproductive Function"Anne Etgen, Ph.D., professor of neuroscience, of psychiatry and behavioral sciences, and of pediatrics; and...

Major NSF grant boosts UNH research on hormonal genomics

...ome a model for analysis of several systems, including the evolution of the neuroendocrine regulation of reproduction. For neuroendocrine studies, the availability of the lamprey genome, mapped in 2005, offers ric...

European Multidisciplinary Conference on Thoracic Oncology

...mplications Heterogeneity of locally advanced lung cancer and its implications for treatment Chemoradiotherapy and new developments in radiotherapy neuroendocrine tumors, mesothelioma and thymoma Individualized therapy based on tumor features Elderly and co-morbid patients Future developments in multidiscipli...

New and unexpected mechanism identified how the brain responds to stress

...uroscience and professor of Psychiatry at Laval University. "I was fascinated when I learned of this work. It has not been clear till now how the neuroendocrine stress response was activated by external stressors. Bains' work shows a complex, yet elegant solution, involving a switch from inhibition to excitat...

Depression during pregnancy can double risk of preterm delivery

...ging evidence that depression during early pregnancy may interfere with the neuroendocrine pathways and subsequently placental function. The placenta and neuroendocrine functions play an important role in maintaining the health of a pregnancy a...

As rates rise, researchers find better way to identify melanoma

...gy and Laboratory Medicine at URMC. Xu and his colleagues have previously published studies of IMP-3 as a potential therapeutic target for high grade neuroendocrine carcinomas. ...

Pioneers in small RNA research to present at UD symposium, April 16

... winners: Walter Gilbert at Harvard and H. Robert Horvitz at MIT. In addition to microRNA and RNA interference, Ruvkun's research interests include neuroendocrine control of metabolism, aging and molting, as well as microbial diversity. Ruvkun has written more than 100 research papers and has several issued a...

Chemicals used as fire retardants could be harmful, UC-Riverside researchers say

... be compromised by PBDEs and PCBs. This summer, the three researchers reported in Toxicological Sciences that PBDEs, like PCBs, can disrupt the neuroendocrine system, which regulates the secretion of hormones such as those responsible for body water regulation and cardiovascular function. At present, one ...
Neuroendocrine in Biological Technology

Lexicon Initiates Phase 2 Clinical Trial of LX1032 in Patients With Carcinoid Syndrome

...signation from the U.S. Food and Drug Administration. About Carcinoid Syndrome Carcinoid syndrome is a chronic condition caused by metastatic neuroendocrine tumors that usually originate from the gastrointestinal tract. These tumors secrete large amounts of serotonin, which can cause a variety of symptoms...

Delcath Systems Granted Third Orphan Drug Designation

... drug melphalan for the treatment of patients with neuroendocrine tumors. (Logo: http://www.newscom.com/cgi-bi...h doses of the drug melphalan for the treatment of neuroendocrine tumors metastatic to the liver. The trial is trea...lanoma. High dose melphalan, for the treatment of neuroendocrine tumors, is an indication that we have aggressively...

Cardiovascular Side Effects of Pioglitazone and Rosiglitazone Linked to Vascular and Energy Pathways by Genomas Clinical Study

...ng either pioglitazone or rosiglitazone. A total of 222 cardiometabolic and neuroendocrine genes were selected and a physiogenomic analysis was performed. For BMI, th...diabetic care, we can assess that genes in interlocking cardiometabolic and neuroendocrine pathways can be integrated into a PhyzioType System, a multi-gene array and...

Delcath Adds University of Pittsburgh Medical Center to Phase III Trial

...o lead the trial at Pittsburgh as we complete enrollment in this study, and explore other viable options for its use, including colorectal metastasis, neuroendocrine metastasis and primary liver cancer." Richard L. Taney, President and CEO of Delcath commented, "Dr. Pingpank has continued his commitment ...

CISBIO Bioassays Launches Chromoa(TM) Chromogranin A ELISA Kit

...l laboratories for the detection and monitoring of neuroendocrine tumors. Chromoa is a highly-sensitive, monoclona... identify increased protein levels in serum when a neuroendocrine tumor is present in the human body. The most common neuroendocrine tumors affect the adrenal gland, the pancreas and ...

/C O R R E C T I O N -- Rosetta Genomics Ltd/

...on-small cell lung cancer, lung cancer vs. thymoma, and carcinoid vs. other neuroendocrine tumors. - Identified specific microRNAs that are markers to differentiate...on-small cell lung cancer, lung cancer vs. thymoma, and carcinoid vs. other neuroendocrine tumors. - Identified specific microRNAs that are markers to differentiate...

Rosetta Genomics Reports First Quarter 2008 Financial Results

...ll cell lung cancer vs. small-cell lung cancer, neuroendocrine tumors vs. non-small cell lung cancer, lung cancer vs. thymoma, and carcinoid vs. other neuroendocrine tumors. - Identified specific microRNAs that are markers to differentiate between primary liver and brain tumors and metastases to these organs. -...

Rosetta Genomics Reports Fourth-Quarter and Full-Year 2007 Financial Results

...ing in lung cancer: primary vs. metastases, neuroendocrine tumors vs. - non-small cell lung cancer, lung cancer vs. thymoma, and carcinoid vs. other neuroendocrine tumors. - Identified specific microRNAs that are markers to differentiate between primary liver and brain tumors and metastases to these organs. -...

EntreMed Presents Interim Results for Phase 2 Carcinoid Tumor Study

...with this combination." About Carcinoid Tumors Carcinoids are tumors of neuroendocrine origin. Approximately 85% of carcinoid tumors develop in the gastrointestin...herapy offers limited benefit to patients with metastatic carcinoid tumors. neuroendocrine tumors are known to be highly vascularized, suggesting the use of antiangio...

Lexicon Files Investigational New Drug Application for LX1032 as a Potential Treatment for Carcinoid Syndrome

...es severe diarrhea and abdominal discomfort. Carcinoid tumors are a type of neuroendocrine tumor and, according to the American Cancer Society, about 11,000 to 12,000 neuroendocrine tumors and neuroendocrine cancers are diagnosed each year in the United States. About 10% of people w...
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