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Neurite in Medical News

USC researchers identify key mechanism that regulates the development of stem cells into neurons

...l stem cells and neurons are unclear, Lu notes. Ryk functions as a receptor of Wnt proteins required for cell-fate determination, axon guidance and neurite outgrowth in organisms. Researchers at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC analyzed sections of th...

New Mount Sinai research tracks effects of addictive drugs on brain

...on the human brain. Researchers have just published the new breakthrough study, Design Logic of a Cannabinoid Receptor Signaling Network that Triggers neurite Outgrowth, in the latest issue of Science on May 16th, 2008. The research findings give us a new window into the brain, helping us to better unde...

Researchers Map Paths Governing Neuron Function

...egulated by a complex protein network that control neurite outgrowth. The formation of neurites is the fir...goal is to identify unique proteins that cause the neurite to sprout and differentiate. We also want to understand the underlying signals that guide neurite formation and migration in response to directional...

Neurotransmitters in biopolymers stimulate nerve regeneration

...esults in a biomaterial that successfully promotes neurite growth, which is necessary for victims of central ...ylcholine was chosen because it is known to induce neurite outgrowth and promote the formation and strengthen...ia sprouted at least 20 neurites and then measured neurite length and...

2007 EURYI: 20 researchers to receive Nobel Prize-sized awards in Helsinki

...igenetic mechanisms in learning processes, age related cognitive decline and neurodegenerative diseases Dr. Karl Gademann (Switzerland) - Directing neurite outgrowth through synthetic natural products Dr. Sonia Garel (France) - Wiring the forebrain: roles and mechanisms of tangential cell migration in ...

Nanomedicine Gives the Way for Nerve Cell Regeneration

... "By providing mechanical tension to the regrowing axon, we may be able to enhance the regenerative axon growth in vivo". This mechanically induced neurite outgrowth may provide a possible method for bypassing the inhibitory interface and the tissue beyond a CNS related injury. Using optic nerve and spina...
Neurite in Medical Technology

Cogane Data Presented at ‘11th International Congress of Parkinson’s Disease and Disorders’

...inducer that readily crosses the blood brain barrier. In pre-clinical studies, Cogane(tm) stimulates the release of neuronal growth factors, increases neurite outgrowth and protects against neuronal degeneration. Importantly, Cogane(tm) also reverses the decrease of neuronal growth factors and reverses dopam...

Research Documents Scalable Production, Survival Following Engraftment and Positive Impact on Cardiac Function in Infarcted Rats for Geron's Human Embryonic Stem Cell-Based Therapeutic for Heart Failure

...splantation into rats with acute spinal cord injuries, GRNOPC1 stimulated extensive remyelination of neurons, improved neuronal survival and increased neurite outgrowth in damaged areas of the cord. This resulted in improved hind-limb locomotor activity. Geron scientists presented additional studies showin...
Neurite in Biological News

Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age

...functions. The hippocampus plays an important role in memory and learning. The study, "Exercise enhances the proliferation of neural stem cells and neurite growth and survival of neuronal progenitor cells in dentate gyrus of middle-aged mice," was carried out by Chih-Wei Wu, Ya-Ting Chang, Lung Yu, Hsiun-...

Researchers reveal types of genes necessary for brain development

... algorithms to help streamline the analysis of the thousands of images created in the process. The analysis revealed unexpected, essential roles in neurite outgrowth for genes representing a wide range of functional categories including signaling molecules, enzymes, channels, receptors, and cytoskeletal p...

MIT IDs proteins key to brain function

...w neurites form could eventually lead to therapies involving stimulation of neurite growth, said Gertler. You could use these insights to help repair injuri... but the researchers were surprised to find that they are also critical for neurite formation, Gertler said. Ena/VASP proteins are located in the tips of a...

News tips from the Journal of Neuroscience

... Spontaneous Astrocytic Ca 2+ Oscillations and neurite Growth Kazunori Kanemaru, Yohei Okubo, Kenzo Hi...ations in cultured astrocytes and the promotion of neurite growth. Their results reveal a role for the membra...evoked astrocytic Ca 2+ transients did not affect neurite outgrowth. The messenger was not diffusible becaus...

Invasion of the brain tumors

... mechanisms underlying this invasive behavior. They identified the neurotrophin receptor p75NTR, which normally functions during development to induce neurite outgrowth and promote neuronal cell death, as an important regulator of glioma invasion. The researchers present the first evidence that this neurotro...

Widely used iron nanoparticles exhibit toxic effects on neuronal cells

...n the concentration of nanoparticles led to the production of two neurites per cell, and a 10-fold increase of that concentration resulted in only one neurite per cell. Additionally, neurites produced in response to the growth factor in the presence of iron oxide nanoparticles were less well formed and also ...

Engineers improve plastic's potential for use in implants by linking it to biological material

.... "We can apply an electric field to this synthetic material and enhance neurite repair," said Schmidt. The newly gained ability to attach proteins to polyp... factors could also be linked to this plastic wrapping, further stimulating neurite regeneration. Working with Schmidt and Belcher, the paper's lead authors...
Neurite in Biological Technology

Otonomy Introduces Scientific Advisory Board

...SDSU audiology doctoral programs. His research focuses on the development, damage, survival and regeneration of hair cells, regulation of survival and neurite extension in cochlear neurons, as well as the biology of middle ear inflammation, tissue growth and recovery during otitis media. Dr. Ryan completed p...

Medivation Presents New Data on Dimebon's Novel Mechanism of Action

...wo key aspects of brain cell function: it promoted neurite outgrowth and it preserved mitochondrial function ...in an oral presentation, entitled "Dimebon Induces neurite Outgrowth and Stabilization in the Setting of Cell...on induced a statistically significant increase in neurite outgrowth from cortical, hippocampal and spinal co...

An Image-Based Assay of Endothelial Cell Tube Formation as a Model of Angiogenesis

...e flatness even before the image was analyzed. Image analysis was conducting using the new BD Tube Formation Module, an advanced development of the BD neurite Outgrowth Module (Cat. No. 346203). The algorithm thresholds the cells from the background and identifies a number of features including, the total le...

Neurite outgrowth cell-by-cell analysis using the IN Cell Developer Toolbox

... Key words: neurite outgrowth • cell-by-cell • fluorescent i...bull; IN Cell Developer Toolbox neurite extension, or neurite outgrowth, plays a fundamental role in embryonic d...

The Bio-Rad Silver Stain, Rev E

...tting, Proc Natl Acad Sci USA 82, 47174721 (1985) 35. Kligman D and Marshak DR, Purification and characterization of a neurite extension factor from bovine brain, Proc Natl Acad Sci USA 82, 71367139 (1985) 36. Kondo I et al., Genetic analysis of human lymp...

Reagents for Up and Down-Regulation of miRNA Activity in Mammalian Cells

... the cells transfected with the miR-31 inhibitor become elongated and display thin membrane protrusions similar in appearance to neurite outgrowths (Figure 5, left inset). The negative control data was identical to the nontransfected control (Figure 5, right inset). Additiona...

Setting up a kinase profiler with IMAP

...A. Mishima, M. Hagiwara, M. Sano, K. Hayashi, T. Inoue, K. Naito, T. Toshioka, H. Hidaka. Inhibition of forskolininduced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase,...

Efficient RNAi-mediated gene silencing in neuronal cells using QIAGEN siRNA and TransMessenger Transfection Reagent*

... Caceres, A., Muatinoem J., and Kosik, K. (1992) Suppression of MAP2 in cultured cerebellar macroneurons inhibits minor neurite formation. Neuron. 9, 607. Transfection Reagent Selector Kit Handbook * Data excerpted from...

Efficient DNA transfection of primary CNS neurons using TransMessenger Transfection Reagent

...en thin neurites are clearly visible. The neurite network is intact and the neurons are wel...-MAP2 antibodies reveals a well-developed neurite network and brightly stained somata, indi...ted and GFP fluorescence is seen in their neurite network and somata. " Excellent Morpholog...
Neurite in Biological Products

BD Pathway 435 confocal bioimager from BD Biosciences - Bioimaging

Description:...r simplifies the process of high-content cellular analysis. The system enables a broad array of fluorescence-based biological applications* such as neurite outgrowth analysis, angiogenesis, protein translocation, colocalization, cell cycle, and 3-dimensional cellular exploration. The BD Pathway 435 is ide...
Company:BD Biosciences - Bioimaging
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