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Nephropathy in Medical News

Genentech/Roche's Lucentis and Eli Lilly's Ruboxistaurin Will Drive the Diabetic Retinopathy and Nephropathy Drug Markets

Longer Term Growth of Diabetic Neuropathy Market Will Be Driven by Launches of Disease-Modifying Therapies, According to a New Report from Decision Resources WALTHAM, Mass., Sept. 24 /PRNewswire/ -- Decision Resources, one of the world's leading research and advis...

Study compares strategies for BK virus nephropathy

For kidney transplant recipients with a serious complication called BK virus-associated nephropathy (BKVAN), promptly cutting back on anti-rejection drugs reduces the risk of losing the kidney (graft loss), according to a report in the November Clinical Journal of the American Society of Nephrolo...

Ruboxistaurin As A Novel Treatment For Diabetic Nephropathy

Recent research, which appears in the current issue of Diabetes Care, establishes Ruboxistaurin as a promising novel treatment that may improve upon established therapies for diabetic nephropathy//. Nephropathy is known to develop in 40% of people with type 2 diabetes and is the leadi...

Nutrition Guide For Diabetic Nephropathy

Diabetes is a chronic illness that requires continuing medical care and patient self-management education to prevent acute complications and to reduce the risk of long-term complications//. As the prevalence of diabetes continues to soar, primary care practitioners are confronted with an ever-incre...

Immunoglobulin Can Predict Some Diabetic Complications

...rdiovascular complications in people with type 1 diabetes who have diabetic nephropathy (DN) -- kidney damage caused by diabetes. The study included 139 patient...formation The MedlinePlus Medical Encyclopedia has more about diabetic nephropathy . -- Robert Preidt ...

PLC Medical Systems Announces Publication of Care Study Update

... in Renally Impaired Patients (CARE) Study determined that Contrast-Induced nephropathy (CIN) is associated with long-term adverse events, ranging from pulmonary e...r RenalGuard as a safe and effective prevention device for contrast induced nephropathy may not be completed in a timely fashion, if at all, or, if these clinical ...

PLC Systems Reports First Quarter 2009 Results

...rent clinical trial in Italy and the planned future U.S. clinical trial for RenalGuard as a safe and effective prevention device for contrast induced nephropathy may not be completed in a timely fashion, if at all, or, if these clinical trials are completed, they may not produce clinically significant or meanin...

PLC Systems Reports Fourth Quarter 2008 Results

...h the EU launch and in raising additional funding for the U.S. clinical trial to investigate the efficacy of RenalGuard in preventing Contrast Induced nephropathy (CIN)." Mr. Tauscher added, "Our core TMR business in the U.S. continues to provide a base level of revenues, primarily through kit sales and o...

New Test May Help Kidney Transplant Patients

...tered viral aggregates that form in the kidneys of people with polyomavirus nephropathy and are excreted in the urine. The researchers said the test takes three...Society of Nephrology . "An early and accurate diagnosis of polyomavirus nephropathy will result in a better understanding of the disease and ultimately improve...

FDA Puts Black-Box Warning on Bowel-Cleansing Drugs

...would now require a black-box warning on the oral sodium phosphate products Visicol and OsmoPrep, alerting consumers about the risk of acute phosphate nephropathy -- a type of severe kidney injury. "The FDA has received reports of 20 unique cases of kidney injury associated with the use of OsmoPrep," Dr. Joyc...
Nephropathy in Medical Technology

Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy

Trial to Evaluate Safety of CCL2-LPM for Inflammatory Kidney Disease SAN FRANCISCO, April 14 /PRNewswire/ -- Osprey Pharmaceuticals U.S.A., Inc. announced today that patient dosing has commenced in a Phase Ib clinical trial of the company's lead compound, CCL2-LPM, for the treatment of IgA ne...

Exelixis Reports Top-Line Results of the Phase 2 Trial of XL784 in Patients With Proteinuria Associated With Diabetic Nephropathy

- Data to be presented November 2 at the American Society of Nephrology Meeting - SOUTH SAN FRANCISCO, Calif., Oct. 16 /PRNewswire-FirstCall/ -- Exelixis, Inc. (Nasdaq: EXEL ) announced that a recently completed phase 2 trial of XL784 did not meet its primary end...

Research: Popular Diabetes Medications Associated with Increase in Bone Fractures

...ong people with diabetes. The American Diabetes Association recommends ACE-I or ARB in diabetic patients with certain clinical conditions such as nephropathy or hypertension. Unfortunately, these agents are not frequently prescribed to many patients for whom treatment is indicated. In the Medco study, a f...

PLC Medical Systems to Demonstrate RenalGuard(R) at EuroPCR 2009

...plan to demonstrate how RenalGuard is used to help prevent Contrast-Induced nephropathy (CIN) in a patient with impaired renal function undergoing a Percutaneous C...r RenalGuard as a safe and effective prevention device for contrast induced nephropathy may not be completed in a timely fashion, if at all, or, if these clinical ...

RenalGuard(R) Pilot Safety Clinical Trial Data to be Presented at ACC 2009

...signed to test the safety of the RenalGuard System(TM) when used to provide high volume matched diuresis in patients at high risk for Contrast-Induced nephropathy (CIN) undergoing angiography. A total of 23 patients were enrolled in the study, which was completed in late 2007. The lead investigator for the tri...

PLC Systems Receives Full FDA Approval for Pivotal Study of RenalGuard(TM) in The U.S.

...rd System(TM) and associated therapy in the prevention of Contrast-Induced nephropathy (CIN). The FDA also approved PLC's request to expand their investi...ent in the trial will now include 406 patients. Contrast-Induced nephropathy Approximately seven million patients worldwide undergo intervent...

PLC Systems Defers Pivotal Study of RenalGuard(TM) in the U.S.

...PLC ) announced today that it will defer the commencement of the U.S. pivotal trial of its RenalGuard(TM) System in the prevention of Contrast-Induced nephropathy (CIN). The company continues to support the investigator-sponsored clinical trial now ongoing in Milan, Italy as well as the limited market launch of ...

New Study Shows BENICAR(R) (olmesartan medoxomil) Reverses Blood Vessel Damage Independent of Blood Pressure Lowering

...ucted at 200 sites in 20 countries involving 4,400 patients. Another study, titled "Olmesartan Reducing Incidence of End stage renal stage in diabetic nephropathy Trial," or ORIENT, targeting Japanese and Hong Kong Chinese patients, is investigating the suppressive effects of the drug against the progression of ...

Synvista Therapeutics Reports Results of Three Phase 2 Clinical Trials of SYI-2074 in Diabetic Patients with Cardiovascular Disease

... About Synvista Therapeutics Synvista Therapeutics is a biopharmaceutical company developing drugs to treat and prevent cardiovascular disease and nephropathy in people with diabetes. The Company believes it has identified several product candidates that represent novel approaches to some of the largest phar...

PLC Systems Announces Approval of First European Study to Evaluate RenalGuard(TM)

...nalGuard(TM) in the prevention of Contrast-Induced nephropathy (CIN) in high-risk patients undergoing catheteriza... be provided using RenalGuard. "Contrast-Induced nephropathy is a risky complication resulting from the use of ...deadly medical condition known as Contrast-Induced nephropathy (CIN). Patients undergoing image-guided procedures...
Nephropathy in Medical Products

ImmunoDip Test For Microalbuminuria

Description:...y for independent verification of these results. Early detection of low levels of urinary albumin allows early intervention in cases of Subclinical nephropathy in Diabetes and Hypertension. Microalbuminuria is now accepted as highly predictive of cardiovascular risk in hypertensive individuals....
Company:Diagnostics Chemicals Limited
Nephropathy in Medical Definition

Pathology

..., type 2 , coma , angiopathy , ketoacidosis , nephropathy , neuropathy , retinopathy ) - Hypoglycemia - ...on Hypertensive heart disease - Hypertensive nephropathy - Secondary hypertension - Renovascular hypert...| Focal segmental glomerulosclerosis | Diabetic nephropathy | IgA...
Nephropathy in Medical Dictionary

Nephropathy

Causes of nephropathy include administration of analgesics, xanthine oxidase ... Analgesic nephropathy · Renal osteodystrophy · Nephroptosis · Abderhalden ... Diabetic nephropathy , also known as Kimmelstiel-Wilson syndrome and intercapillary glomerulonephritis, is a progressive kid...

Reflux nephropathy

Reflux nephropathy , RN is a term applied when small and scarred kidneys are associated with vesico-ureteric reflux (VUR). CPN being the commonest cause, there are other causes including analgesic nephropathy and obstructive injury. Scarring is essential in developing RN... Reflux nephr...

Membranous nephropathy

Membranous glomerulonephritis (MGN) is a slowly progressive disease of the kidney affecting mostly patients between ages of 30 and 50 years, usually Caucasian. Membranous nephropathy is a kidney disorder which involves changes and ... Membranous nephropathy is caused by thickeni...

IgA nephropathy

IgA nephropathy is a form of glomerulonephritis . This should not be confused with Buerger's disease, an unrelated condition. What are the major symptoms of IgA Nephropathy ? What other side effects or symptoms does IgA Nephropathy have? ... How does one get IgA Nephropathy ...

Analgesic nephropathy

Analgesic nephropathy is injury to the kidney caused by analgesic medications such as aspirin, phenacetin, and paracetamol. The term usually refers to damage induced by excessive use of combinations of these medications,... Explains how daily use of analgesics over long periods may ...

Nephrosis

...r is a cancerous tumor of the kidney. This tumor occurs in children. ... Nephrosis . Polycystic kidney disease. Post-streptococcal GN. Reflux nephropathy ... Penn State Children's Hospital provides world class care and services to patients. ... However, in most children, we still don't know why ne...

Kidney Diseases

...c, and might include feeling generally unwell and experiencing a reduced... (Redirected from Kidney disease ) Jump to: navigation, search ... nephropathy refers to damage to or disease of the kidney . An older term for this is nephrosis. ... The kidneys play a critical role in health. When some...

Kidney disease

... and might include feeling generally unwell and experiencing a reduced... (Redirected from Kidney disease ) Jump to: navigation, search ... nephropathy refers to damage to or disease of the kidney . An older term for this is nephrosis. ... The kidneys play a critical role in health. When so...

Interstitial nephritis

...nterstitial nephritis is a kidney disorder in which the spaces between the ... to a drug (acute interstitial allergic nephritis ) Analgesic nephropathy ... ...
Nephropathy in Biological News

Enzyme involved in inflammatory bowel disease discovered at Penn State College of Medicine

...he meprin proteases. With colleagues from the National Institutes of Health, she found a linkage between the meprin gene and vulnerability to diabetic nephropathy in Pima Indians in the southwestern United States. "These types of transitional research that provide sound basic understanding of a disease proce...

Researchers may have found why women have an edge on salt-sensitive hypertension

...curs in some patients taking powerful new ETA antagonists, which are in use for pulmonary hypertension and under study for conditions such as diabetic nephropathy and uncontrolled hypertension. These antagonists block the action of ETA receptors which are believed to raise blood pressure and help reshape blood v...

Joslin discovers signs of residual islet cell function in people with long-term type 1 diabetes

...uration of type 1 diabetes 57 years. The data collected so far show that individuals who have survived 50 years or more have a greatly reduced risk of nephropathy and retinopathy. ...

Genetically engineered animals help in scientific research that may benefit children

...ped us to decide which molecules to study, or which might be interesting targets for drug development in human chronic kidney disease." Obstructive nephropathy or obstructive uropathy, the kidney disease on which this animal model is based, is frequently found in children and is the first cause of end-stage r...

New type of rejection blocker protects kidneys after transplant

...ing both the intensive and less intensive belatacept regimens compared to cyclosporine patients. Another indicator of kidney health, chronic allograft nephropathy (scarring of the kidney), also was lower at 12 months among patients receiving either of the belatacept regimens. Patients in all treatment groups...
Nephropathy in Biological Technology

Astellas Receives FDA Approval for Use of Prograf(R) (Tacrolimus) in Conjunction With Mycophenolate Mofetil (MMF) in Kidney Transplant Recipients

... is suspected or diagnosed, immediate reduction of immunosuppression is advised. Activation of latent viral infections, including BK virus-associated nephropathy and JC virus-associated progressive multifocal leukoencephalopathy (PML), has also been reported. These viral infections may lead to serious, includin...

Pharmalink AB Completes Phase II Clinical Study With Renal Disease Drug Nefecon(R)

... World Congress of Nephrology 2009, 22-26 May in Milan (Smerud et al, Enteric Budesonide Ameliorates Albuminuria and Glomerular Filtration Rate in IgA nephropathy Patients) and at the satellite meeting, IgA Nephropathy, 26-28 May in Stresa, Italy. "It is very gratifying to have completed this important st...

Nile Therapeutics Announces Focus on CD-NP for Acute Heart Failure and Termination of 2NTX-99 Program

...NTX-99 suggests potential utility in a range of atherosclerotic, thrombotic, and microvascular diseases, including intermittent claudication, diabetic nephropathy and pulmonary arterial hypertension. About Nile Therapeutics Nile Therapeutics, Inc. is a clinical-stage biopharmaceutical company that devel...

Synvista Therapeutics Announces Progress in Phase 2 Clinical Trial Program for Alagebrium

...linical candidate for interfering with A.G.E.-related sclerosis and fibrosis of the heart, kidney and other tissues leading to heart failure, diabetic nephropathy and other disorders. It is a proprietary A.G.E. crosslink breaker that is designed to function unlike any previously developed pharmaceutical agents t...

Synvista Therapeutics Announces Initiation of the BREAK Study of Alagebrium for Diastolic Heart Failure

...s of the heart, kidney and other tissues leading to heart failure, diabetic nephropathy and other disorders. It is a proprietary A.G.E. crosslink breaker that func...al company developing drugs to treat and prevent cardiovascular disease and nephropathy in people with diabetes. The Company believes it has identified several pro...

Synvista Therapeutics to Present at Acumen BioFin Rodman & Renshaw 5th Annual Global Healthcare Conference

...-2074) in cardiovascular diseases, alagebrium in heart failure and diabetic nephropathy and progress on the company's Haptoglobin diagnostic test. He will also pro...al company developing drugs to treat and prevent cardiovascular disease and nephropathy in people with diabetes. The Company believes it has identified several pro...

Synvista Therapeutics Increases Commercial Focus by Appointing David C. Tantillo Senior Director of Marketing and Sales

... About Synvista Therapeutics Synvista Therapeutics is a biopharmaceutical company developing drugs to treat and prevent cardiovascular disease and nephropathy in people with diabetes. The Company believes it has identified several product candidates that represent novel approaches to some of the largest phar...

PLC Systems to Host First Quarter Conference Call on May 15, 2008

...oval to commence a U.S. pivotal trial to study the effectiveness of its RenalGuard Therapy and RenalGuard System in the prevention of Contrast-Induced nephropathy (CIN). RenalGuard Therapy is designed to reduce the toxic effects that contrast media can have on the kidneys. This therapy is based on the theory tha...

Synvista Therapeutics Highlights Newly Published Data Demonstrating the Value of Haptoglobin Genotype Testing In People with Diabetes

... About Synvista Therapeutics Synvista Therapeutics is a biopharmaceutical company developing drugs to treat and prevent cardiovascular disease and nephropathy in people with diabetes. The Company believes it has identified several product candidates that represent novel approaches to some of the largest phar...

Exelixis Announces Full Year and Fourth Quarter 2007 Financial Results

...op XL784. Based on encouraging data from a subgroup analysis, the compound may nevertheless have potential to benefit patients with diabetic nephropathy and we are actively pursuing ways to monetize this asset. -- Extended our research collaboration agreement with Bristol-Myers Squibb Compa...
Nephropathy in Biological Definition

Diabetes mellitus

...ction and gangrene , sometimes requiring limb amputation , see below nephropathy (due to microangiopathy ) which can lead to renal failure Larg...al control of hypertension plays a pivotal role in preventing both diabetic nephropathy and cardiovascular disease. There is emerging solid evidence that full-b...

Insulin

...lindness (from proliferative diabetic retinopathy ), toehr vascular damage, nerve damage from diabetic neuropathy , or kidney failure from diabetic nephropathy . These studies have demonstrated beyond doubt that, if it is possible for a patient, so-called intensive insulinotherapy is superior to conventi...

Kidney

...high cholesterol. kidney tumors Wilms tumor Renal cell carcinoma Renal failure (acute and chronic) Glomerulonephritis Diabetic nephropathy Lupus nephritis Dialysis and kidney transplants Generally, one can live fine with just one kidney. If both kidneys do not function proper...
Nephropathy in Biological Dictionary

Telomere

..... Identification of a specific telomere terminal transferase activity in Tetrahymena extracts" ... Telomere length and progression of diabetic nephropathy in patients with type 1 diabetes. ... Telomere dysfunction provokes regional amplification and deletion ... Negative regulator of telomere ...
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